Not logged in Population pharmacokinetics of weight-based compared with fixed dosing of CAP256V2LS, a broadly neutralizing antibody for HIV prevention in women Mahomed, Sharana; Beliveau, Martin; Heredia-Ortiz, Roberto; Osman, Farzana; Letsoalo, Marothi; Garrett, Nigel; Gengiah, Tanuja N.; Archary, Derseree; Wang, Jennifer; Narpala, Sandeep; Castro, Mike; Serebryannyy, Leonid; Carlton, Kevin; Koup, Richard A.; Moore, Penny L.; Morris, Lynn; Karim, Quarraisha Abdool; Karim, Salim S. Abdool Share Save
Resistance mutations that distinguish HIV-1 envelopes with discordant VRC01 phenotypes from multi-lineage infections in the HVTN703/HPTN081 trial: implications for cross-resistance Cohen, Paula; Lambson, Bronwen E.; Mkhize, Nonhlanhla N.; Moodley, Chivonne; Yssel, Anna E. J.; Moyo-Gwete, Thandeka; York, Talita; Gwashu-Nyangiwe, Asanda; Ndabambi, Nonkululeko; Thebus, Ruwayhida; Juraska, Michal; Decamp, Allan C.; Williamson, Brian D.; Magaret, Craig A.; Gilbert, Peter B.; Westfall, Dylan; Deng, Wenjie; Mullins, James I.; Morris, Lynn; Williamson, Carolyn; Moore, Penny L. Share Save
Population shift in antibody immunity following the emergence of a SARS-CoV-2 variant of concern Bhiman, Jinal N.; Madzorera, Vimbai Sharon; Mkhize, Qiniso; Scheepers, Cathrine; Hermanus, Tandile; Ayres, Frances; Makhado, Zanele; Moyo-Gwete, Thandeka; Crowther, Carol; Singh, Beverley; Fortuin, Mirriam; Marinda, Edmore; Jooste, Sean; Zuma, Khangelani; Zungu, Nompumelelo; Morris, Lynn; Puren, Adrian; Simbayi, Leickness; Moyo, Sizulu; Moore, Penny L. Share Save
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High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials ( vol 14 , 8299 , 2023) Reeves, Daniel B.; Mayer, Bryan T.; DeCamp, Allan C.; Huang, Yunda; Zhang, Bo; Carpp, Lindsay N.; Magaret, Craig A.; Juraska, Michal; Gilbert, Peter B.; Montefiori, David C.; Bar, Katharine J.; Cardozo-Ojeda, E. Fabian; Schiffer, Joshua T.; Rossenkhan, Raabya; Edlefsen, Paul; Morris, Lynn; Mkhize, Nonhlanhla N.; Williamson, Carolyn; Mullins, James I.; Seaton, Kelly E.; Tomaras, Georgia D.; Andrew, Philip; Mgodi, Nyaradzo; Ledgerwood, Julie E.; Cohen, Myron S.; Corey, Lawrence; Naidoo, Logashvari; Orrell, Catherine; Goepfert, Paul A.; Casapia, Martin; Sobieszczyk, Magdalena E.; Karuna, Shelly T.; Edupuganti, Srilatha Share Save
Prevention efficacy of the broadly neutralizing antibody VRC01 depends on HIV-1 envelope sequence features Juraska, Michal; Bai, Hongjun; deCamp, Allan C.; Magaret, Craig A.; Li, Li; Gillespie, Kevin; Carpp, Lindsay N.; Giorgi, Elena E.; Ludwig, James; Molitor, Cindy; Hudson, Aaron; Williamson, Brian D.; Espy, Nicole; Simpkins, Brian; Rudnicki, Erika; Shao, Danica; Rossenkhan, Raabya; Edlefsen, Paul T.; Westfall, Dylan H.; Deng, Wenjie; Chen, Lennie; Zhao, Hong; Bhattacharya, Tanmoy; Pankow, Alec; Murrell, Ben; Yssel, Anna; Matten, David; York, Talita; Beaume, Nicolas; Gwashu-Nyangiwe, Asanda; Ndabambi, Nonkululeko; Thebus, Ruwayhida; Karuna, Shelly T.; Morris, Lynn; Montefiori, David C.; Hural, John A.; Cohen, Myron S.; Corey, Lawrence; Rolland, Morgane; Gilbert, Peter B.; Williamson, Carolyn; Mullins, James I. Share Save
High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials Reeves, Daniel B.; Mayer, Bryan T.; Decamp, Allan C.; Huang, Yunda; Zhang, Bo; Carpp, Lindsay N.; Magaret, Craig A.; Juraska, Michal; Gilbert, Peter B.; Montefiori, David C.; Bar, Katharine J.; Cardozo-Ojeda, E. Fabian; Schiffer, Joshua T.; Rossenkhan, Raabya; Edlefsen, Paul; Morris, Lynn; Mkhize, Nonhlanhla N.; Williamson, Carolyn; Mullins, James I.; Seaton, Kelly E.; Tomaras, Georgia D.; Andrew, Philip; Mgodi, Nyaradzo; Ledgerwood, Julie E.; Cohen, Myron S.; Corey, Lawrence; Naidoo, Logashvari; Orrell, Catherine; Goepfert, Paul A.; Casapia, Martin; Sobieszczyk, Magdalena E.; Karuna, Shelly T.; Edupuganti, Srilatha Share Save
Pharmacokinetic serum concentrations of VRC01 correlate with prevention of HIV-1 acquisition Seaton, Kelly E.; Huang, Yund; Karuna, Shelly; Heptinstall, Jack R.; Brackett, Caroline; Chiong, Kelvin; Zhang, Lily; Yates, Nicole L.; Sampson, Mark; Rudnicki, Erika; Juraska, Michal; deCamp, Allan C.; Edlefsen, Paul T.; Mullins, James I.; Williamson, Carolyn; Rossenkhan, Raabya; Giorgi, Elena E.; Kenny, Avi; Angier, Heather; Randhawa, April; Weiner, Joshua A.; Rojas, Michelle; Sarzotti-Kelsoe, Marcella; Zhang, Lu; Sawant, Sheetal; Ackerman, Margaret E.; McDermott, Adrian B.; Mascola, John R.; Hural, John; McElrath, M. Julianna; Andrew, Philip; Hidalgo, Jose A.; Clark, Jesse; Laher, Fatima; Orrell, Catherine; Frank, Ian; Gonzales, Pedro; Edupuganti, Srilatha; Mgodi, Nyaradzo; Corey, Lawrence; Morris, Lynn; Monte, David; Cohen, Myron S.; Gilbert, Peter B.; Tomaras, Georgia D. Share Save
Neutralization profiles of HIV-1 viruses from the VRC01 Antibody Mediated Prevention (AMP) trials Mkhize, Nonhlanhla N.; Yssel, Anna; Kaldine, Haajira; van Dorsten, Rebecca T.; Davis, Amanda S.; Beaume, Nicolas; Matten, David; Lambson, Bronwen; Modise, Tandile; Kgagudi, Prudence; York, Talita; Westfall, Dylan H.; Giorgi, Elena E.; Korber, Bette; Anthony, Colin; Mapengo, Rutendo E.; Bekker, Valerie; Domin, Elizabeth; Eaton, Amanda; Deng, Wenjie; DeCamp, Allan; Huang, Yunda; Gilbert, Peter B.; Gwashu-Nyangiwe, Asanda; Thebus, Ruwayhida; Ndabambi, Nonkululeko; Mielke, Dieter; Mgodi, Nyaradzo; Karuna, Shelly; Edupuganti, Srilatha; Seaman, Michael S.; Corey, Lawrence; Cohen, Myron S.; Hural, John; McElrath, M. Juliana; Mullins, James I.; Montefiori, David; Moore, Penny L.; Williamson, Carolyn; Morris, Lynn Share Save
Safety and pharmacokinetics of escalating doses of neutralising monoclonal antibody CAP256V2LS administered with and without VRC07-523LS in HIV-negative women in South Africa (CAPRISA 012B) : a phase 1, dose-escalation, randomised controlled trial Mahomed, Sharana; Garrett, Nigel; Capparelli, Edmund, V; Osman, Farzana; Mkhize, Nonhlanhla N.; Harkoo, Ishana; Gengiah, Tanuja N.; Mansoor, Leila E.; Baxter, Cheryl; Archary, Derseree; Yende-Zuma, Nonhlanhla; Samsunder, Natasha; Carlton, Kevin; Narpala, Sandeep; McDermott, Adrian B.; Doria-Rose, Nicole A.; Moore, Penny L.; Morris, Lynn; Karim, Quarraisha Abdool; Mascola, John R.; Karim, Salim S. Abdool Share Save
Functional HIV-1/HCV cross-reactive antibodies isolated from a chronically co-infected donor Pilewski, Kelsey A.; Wall, Steven; Richardson, Simone I.; Manamela, Nelia P.; Clark, Kaitlyn; Hermanus, Tandile; Binshtein, Elad; Venkat, Rohit; Sautto, Giuseppe A.; Kramer, Kevin J.; Shiakolas, Andrea R.; Setliff, Ian; Salas, Jordan; Mapengo, Rutendo E.; Suryadevara, Naveen; Brannon, John R.; Beebout, Connor J.; Parks, Rob; Raju, Nagarajan; Frumento, Nicole; Walker, Lauren M.; Fechter, Emilee Friedman; Qin, Juliana S.; Murji, Amyn A.; Janowska, Katarzyna; Thakur, Bhishem; Lindenberger, Jared; May, Aaron J.; Huang, Xiao; Sammour, Salam; Acharya, Priyamvada; Carnahan, Robert H.; Ross, Ted M.; Haynes, Barton F.; Hadjifrangiskou, Maria; Crowe Jr, James E.; Bailey, Justin R.; Kalams, Spyros; Morris, Lynn; Georgiev, Ivelin S. Share Save
Enhanced neutralization potency of an identical HIV neutralizing antibody expressed as different isotypes is achieved through genetically distinct mechanisms Moyo-Gwete, Thandeka; Scheepers, Cathrine; Makhado, Zanele; Kgagudi, Prudence; Mzindle, Nonkululeko B.; Ziki, Rutendo; Madzorera, Sharon; Manamela, Nelia P.; Ayres, Frances; Lambson, Bronwen E.; Richardson, Simone I.; Morris, Lynn; Moore, Penny L. Share Save
Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies Scheepers, Cathrine; Kgagudi, Prudence; Mzindle, Nonkululeko; Gray, Elin S.; Moyo-Gwete, Thandeka; Lambson, Bronwen E.; Oosthuysen, Brent; Mabvakure, Batsirai; Garrett, Nigel J.; Karim, Salim S. Abdool; Morris, Lynn; Moore, Penny L. Share Save
Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition Gilbert, Peter B.; Huang, Yunda; deCamp, Allan C.; Karuna, Shelly; Zhang, Yuanyuan; Magaret, Craig A.; Giorgi, Elena E.; Korber, Bette; Edlefsen, Paul T.; Rossenkhan, Raabya; Juraska, Michal; Rudnicki, Erika; Kochar, Nidhi; Huang, Ying; Carpp, Lindsay N.; Barouch, Dan H.; Mkhize, Nonhlanhla N.; Hermanus, Tandile; Kgagudi, Prudence; Bekker, Valerie; Kaldine, Haajira; Mapengo, Rutendo E.; Eaton, Amanda; Domin, Elize; West, Carley; Feng, Wenhong; Tang, Haili; Seaton, Kelly E.; Heptinstall, Jack; Brackett, Caroline; Chiong, Kelvin; Tomaras, Georgia D.; Andrew, Philip; Mayer, Bryan T.; Reeves, Daniel B.; Sobieszczyk, Magdalena E.; Garrett, Nigel; Sanchez, Jorge; Gay, Cynthia; Makhema, Joseph; Williamson, Carolyn; Mullins, James I.; Hural, John; Cohen, Myron S.; Corey, Lawrence; Montefiori, David C.; Morris, Lynn Share Save
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Alloimmunity to Class 2 Human Leucocyte Antigens May Reduce HIV-1 Acquisition - A Nested Case-Control Study in HIV-1 Serodiscordant Couples Suchard, Melinda S.; Martinson, Neil; Malfeld, Susan; de Assis Rosa, Debbie; Mackelprang, Romel D.; Lingappa, Jairam; Hou, Xuanlin; Rees, Helen; Delany-Moretlwe, Sinead; Goldfein, Hadassa; Ranchod, Heena; Coetzee, David; Otwombe, Kennedy; Morris, Lynn; Tiemessen, Caroline T.; Savulescu, Dana M. Share Save
High-Throughput B Cell Epitope Determination by Next-Generation Sequencing Walker, Lauren M.; Shiakolas, Andrea R.; Venkat, Rohit; Liu, Zhaojing Ariel; Wall, Steven; Raju, Nagarajan; Pilewski, Kelsey A.; Setliff, Ian; Murji, Amyn A.; Gillespie, Rebecca; Makoah, Nigel A.; Kanekiyo, Masaru; Connors, Mark; Morris, Lynn; Georgiev, Ivelin S. Share Save
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