David D. Eisenstat - Publications, H-index & Citations

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David D. Eisenstat

university of alberta

46H-index

264Paper Count

8.8KCitation Count

Published Papers 85

Publication Date

Targeting mutant p53 in cancer: from mechanistic insights to therapeutic strategies

CELLULAR & MOLECULAR BIOLOGY LETTERS

IF10.2

2026-03-31

OAAI

H. Helena Wu; Sarah Leng; David D. Eisenstat; Consolato Sergi; Roger Leng

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The Reliability of Measuring Muscle Cross-Sectional Area in Children Undergoing Treatment for Musculoskeletal Sarcoma

journal of cachexia, sarcopenia and muscle

IF0

2026-02-12

OAAI

Claire Laurie; Leo Donnan; Catherine L. Granger; Alicia J. Spittle; David D. Eisenstat; Timothy Cain; Nisarg Mehta; Christopher Godfrey; Tara L. FitzGerald

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Precision Immunotherapy for Paediatric High-Grade Glioma: PDGFRα CAR T Cells Show Potent Activity in a Rare Patient-Derived Model

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Davenport, Alexander; Wang, Stacie; Wimmer, Verena; Watson, Katherine; Nouri, Yasmin; Quang, Dong Anh; Eisenstat, David; Jenkins, Misty

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Integrated clinical and molecular landscape of disseminated pediatric low-grade glioma

Neuro-Oncology

IF13.4

2025-10-21

PREAI

Adrian B Levine; Julie Bennett; Prabhumallikarjun Patil; Ian Burns; Robert Siddaway; Cyril Li; Joseline Haizel-Cobbina; Mansuba Rana; Richard Yuditskiy; Andrew Son; Yoshiko Nakano; Palak Patel; I-Chen Ho; Michelle Ku; Alexander T Lyons; José E Velázquez Vega; Matthew J Schniederjan; Craig Erker; Chantel Cacciotti; Mariarita Santi; Ernest J Nelson; Sylvia Cheng; Christopher Dunham; Bev Wilson; Karina Black; Frank Van Landeghem; Liana Nobre; David D Eisenstat; Ana S Guerreiro Stücklin; Annette Weiser; Valerie Larouche; Panagiota Giannakouros; Adriana Fonseca; Lane Williamson; Igor L Fernandes; Ashley S Plant-Fox; Adam Fleming; Shawde Campbell; Naureen Mushtaq; Syed Ibrahim Bukhari; Khurram Minhas; Richard T Graham; Scott Raskin; Filip Jadrijevic-Cvrlje; Louise Ludlow; Mary V Macneil; Jean M Mulcahy-Levy; Samantha Demarsh; Kohei Fukuoka; Kai Yamasaki; Tomonari Suzuki; Fumiharu Ohka; Atsufumi Kawamura; Yoshiki Arakawa; Takashi Ishihara; Fumiyuki Yamasaki; Jordan R Hansford; Amanda Luck; Maclean P Nasrallah; Helen Toledano; Roaya M Masoud; Alvaro Lassaletta; Luis Blasco-Santana; John-Paul Kilday; Alisa Talianski; Caroline Davies; James Johnston; Andrew T Hale; Peter B Dirks; James T Rutka; Michael C Dewan; Uri Tabori; Cynthia E Hawkins

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Pediatric Early Rehabilitation in ACute Lymphoblastic LEukemia (PEACE): A Proof-of-Concept Study of an Enhanced Hybrid Delivery Format (Trial Protocol)

REHABILITATION ONCOLOGY

IF0.9

2025-10-01

PREAI

Ospina, Paula A.; Fisher, Sara; Wilson, Beverly A.; Pritchard, Lesley; Eisenstat, David D.; Tandon, Puneeta; McNeely, Margaret L.

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Targeting p53 for immune modulation: Exploring its functions in tumor immunity and inflammation

CANCER LETTERS

IF10.1

2025-05-01

PREAI

Wu, Helena; Leng, Sarah; Eisenstat, David D.; Sergi, Consolato; Leng, Roger

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The ParClusterers Benchmark Suite (PCBS): A Fine-Grained Analysis of Scalable Graph Clustering

PROCEEDINGS OF THE VLDB ENDOWMENT

IF3.3

2025-04-07

PREAI

Yu, Shangdi; Shi, Jessica; Meindl, Jamison; Eisenstat, David; Ju, Xiaoen; Tavakkol, Sasan; Dhulipala, Laxman; Lacki, Jakub; Mirrokni, Vahab; Shun, Julian

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Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage

CELL DEATH DISCOVERY

IF7

2025-04-02

OAAI

Abuetabh, Yasser; Wu, H. Helena; Al Yousef, Habib; Persad, Sujata; Schlosser, Mary-Pat; Eisenstat, David D.; Sergi, Consolato M.; Leng, Roger

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Multidimensional, integrative profiling identifies BCL2L1 methylation as a predictor of MCL1 dependency in pediatric malignancies

JCI INSIGHT

IF6.1

2025-01-23

OAAI

Adjumain, Shazia; Daniel, Paul; Sun, Claire Xin; Bradshaw, Gabrielle; Chew, Nicole J.; Tsui, Vanessa; Lee, Hanbyeol; Loi, Melissa; Zhukova, Nataliya; Habarakada, Dilru; Yoel, Abigail; Vaghjiani, Vijesh G.; Game, Shaye; Ludlow, Louise E.; Neeman, Naama; Sweet-Cordero, E. Alejandro; Eisenstat, David D.; Cain, Jason E.; Firestein, Ron

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IDH-mutant gliomas in children and adolescents - from biology to clinical trials

FRONTIERS IN ONCOLOGY

IF3.3

2025-01-06

OAAI

Evans, Louise; Trinder, Sarah; Dodgshun, Andrew; Eisenstat, David D.; Whittle, James R.; Hansford, Jordan R.; Valvi, Santosh

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REGULATION OF CELL FATE IN PAEDIATRIC HIGH-GRADE GLIOMA BY THE HOMEOBOX TRANSCRIPTION FACTOR DLX2

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Furst, Liam; Roussel, Enola; Leung, Ryan; George, Ankita; Li, Jason; Best, Sarah; Whittle, James; Cain, Jason; Firestein, Ron; Faux, Maree; Eisenstat, David

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If you build it, they will come: the convergence of funding, research and collaboration in paediatric brain cancer clinical trials

MEDICAL JOURNAL OF AUSTRALIA

IF8.5

2024-11-07

OAAI

Hansford, Jordan; Valvi, Santosh; de Boer, Jasper; McCowage, Geoff; Govender, Dinisha; Kirby, Maria; Ziegler, David; Manoharan, Neevika; Hassall, Timothy; Wainwright, Brandon; Alvaro, Frank; Wood, Paul J.; Eisenstat, David; Quang, Dong Anh Khuong; Jenkins, Misty; Dun, Matthew; Laughton, Stephen J.; Endersby, Raelene; Dodgshun, Andrew; Gottardo, Nicholas

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PRIMARY LEPTOMENINGEAL MEDULLOBLASTOMA: A SINGLE-SITE RETROSPECTIVE STUDY OF 5 CASES

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Wells, Olivia; Bhatia, Kanika; Campbell, Marty; Hansford, Jordan R.; Sullivan, Michael; Williams, Molly; Mignone, Cristina; D'Arcy, Colleen; Eisenstat, David D.; Khuong-Quang, Dong-Anh

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PREDICTING EARLY DEATH IN DIFFUSE MIDLINE GLIOMA

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Moloney, Sam; Carruthers, Vickyanne; Davis, Melissa J.; Bhuva, Dharmesh D.; Mignone, Cristina; Singh, Susan; Gardiner, Rebecca E.; Valvi, Santosh; Eisenstat, David D.; Hansford, Jordan R.

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LINKING CELL FATE DETERMINATION IN THE EMBRYONIC FOREBRAIN TO PEDIATRIC HIGH-GRADE GLIOMA

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Furst, Liam M.; Roussel, Enola M.; Leung, Ryan F.; George, Ankita M.; Firestein, Ron; Faux, Maree C.; Eisenstat, David D.

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INTEGRATED CLINICAL AND MOLECULAR CHARACTERIZATION OF 200 DISSEMINATED PEDIATRIC LOW-GRADE GLIOMAS

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Levine, Adrian; Bennett, Julie; Li, Cyril; Rana, Mansuba; Yuditskiy, Richard; Ho, I-Chen; Haizel-Cobbina, Joseline; Hansford, Jordan; Luck, Amanda; Ludlow, Louise; Eisenstat, David; Toledano, Helen; Masoud, Roaya; Fukuoka, Kohei; Yamasaki, Kai; Nakano, Yoshiko; Mushtaq, Naureen; Minhas, Khurram; Bukhari, Syed Ibrahim; Stuecklin, Ana Guerreiro; Weiser, Annette; Jadrijevic-Cvilje, Filip; Fleming, Adam; Campbell, Shawde; Cacciotti, Chantel; Erker, Craig; van Landeghem, Frank; Wilson, Bev; Black, Karina; MacNeil, Mary; Cheng, Sylvia; Dunham, Chris; Larouche, Valerie; Giannakouros, Panagiota; Fonseca, Adriana; Williamson, Lane; Plant-Fox, Ashley; Levy, Jean Mulcahy; Demarsh, Samantha; Vega, Jose Velazquez; Patil, Prabhumallikarjun; Nasrallah, MacLean; Santi-Vicini, Mariarita; Nelson, Ernest; Graham, Richard; Raskin, Scott; Fernandes, Igor; Dewan, Michael; Tabori, Uri; Hawkins, Cynthia

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The Landscape of Pediatric High-Grade Gliomas: The Virtues and Pitfalls of Pre-Clinical Models

BIOLOGY-BASEL

IF3.5

2024-06-07

OAAI

Furst, Liam M.; Roussel, Enola M.; Leung, Ryan F.; George, Ankita M.; Best, Sarah A.; Whittle, James R.; Firestein, Ron; Faux, Maree C.; Eisenstat, David D.

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Precision-guided treatment in high-risk pediatric cancers

NATURE MEDICINE

IF50

2024-06-06

OAAI

Lau, Loretta M. S.; Khuong-Quang, Dong-Anh; Mayoh, Chelsea; Wong, Marie; Barahona, Paulette; Ajuyah, Pamela; Senapati, Akanksha; Nagabushan, Sumanth; Sherstyuk, Alexandra; Altekoester, Ann-Kristin; Fuentes-Bolanos, Noemi A.; Yeung, Veronica; Sullivan, Ashleigh; Omer, Natacha; Diamond, Yonatan; Jessop, Sophie; Battaglia, Lauren; Zhukova, Nataliya; Cui, Louise; Lin, Angela; Gifford, Andrew J.; Fleuren, Emmy D. G.; Dalla-Pozza, Luciano; Moore, Andrew S.; Khaw, Seong-Lin; Eisenstat, David D.; Gottardo, Nicholas G.; Wood, Paul J.; Tapp, Heather; Alvaro, Frank; McCowage, Geoffrey; Nicholls, Wayne; Hansford, Jordan R.; Manoharan, Neevika; Kotecha, Rishi S.; Mateos, Marion K.; Lock, Richard B.; Tyrrell, Vanessa; Haber, Michelle; Trahair, Toby N.; Cowley, Mark J.; Ekert, Paul G.; Marshall, Glenn M.; Ziegler, David S.

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Management of patients with diffuse intrinsic pontine glioma in Australia and New Zealand: Australian and New Zealand Children's Haematology/Oncology Group position statement

MEDICAL JOURNAL OF AUSTRALIA

IF8.5

2024-05-03

OAAI

Valvi, Santosh; Manoharan, Neevika; Mateos, Marion K.; Hassall, Timothy E. G.; Ziegler, David S.; McCowage, Geoffrey B.; Dun, Matthew D.; Eisenstat, David D.; Gottardo, Nicholas G.; Hansford, Jordan R.

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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-02-06

OAAI

Duchatel, Ryan J.; Jackson, Evangeline R.; Parackal, Sarah G.; Kiltschewskij, Dylan; Findlay, Izac J.; Mannan, Abdul; Staudt, Dilana E.; Thomas, Bryce C.; Germon, Zacary P.; Laternser, Sandra; Kearney, Padraic S.; Jamaluddin, M. Fairuz B.; Douglas, Alicia M.; Beitaki, Tyrone; McEwen, Holly P.; Persson, Mika L.; Hocke, Emily A.; Jain, Vaibhav; Aksu, Michael; Manning, Elizabeth E.; Murray, Heather C.; Verrills, Nicole M.; Sun, Claire Xin; Daniel, Paul; Vilain, Ricardo E.; Skerrett-Byrne, David A.; Nixon, Brett; Hua, Susan; de Bock, Charles E.; Colino-Sanguino, Yolanda; Valdes-Mora, Fatima; Tsoli, Maria; Ziegler, David S.; Cairns, Murray J.; Raabe, Eric H.; Vitanza, Nicholas A.; Hulleman, Esther; Phoenix, Timothy N.; Koschmann, Carl; Alvaro, Frank; Dayas, Christopher, V; Tinkle, Christopher L.; Wheeler, Helen; Whittle, James R.; Eisenstat, David D.; Firestein, Ron; Mueller, Sabine; Valvi, Santosh; Hansford, Jordan R.; Ashley, David M.; Gregory, Simon G.; Kilburn, Lindsay B.; Nazarian, Javad; Cain, Jason E.; Dun, Matthew D.

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Research Directions