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A candidate antibody drug for prevention of malaria Williams, Katherine L.; Guerrero, Steve; Flores-Garcia, Yevel; Kim, Dongkyoon; Williamson, Kevin S.; Siska, Christine; Smidt, Pauline; Jepson, Sofia Z.; Li, Kan; Dennison, S. Moses; Mathis-Torres, Shamika; Chen, Xiaomu; Wille-Reece, Ulrike; Macgill, Randall S.; Walker, Michael; Jongert, Erik; King, C. Richter; Ockenhouse, Christian; Glanville, Jacob; Moon, James E.; Regules, Jason A.; Tan, Yann Chong; Cavet, Guy; Lippow, Shaun M.; Robinson, William H.; Dutta, Sheetij; Tomaras, Georgia D.; Zavala, Fidel; Ketchem, Randal R.; Emerling, Daniel E. Share Save
Framework Mutations of the 10-1074 bnAb Increase Conformational Stability, Manufacturability, and Stability While Preserving Full Neutralization Activity Kerwin, Bruce A.; Bennett, Chelsey; Brodsky, Yan; Clark, Rutilio; Floyd, J. Alaina; Gillespie, Alison; Mayer, Bryan T.; McClure, Megan; Siska, Christine; Seaman, Michael S.; Seaton, Kelly E.; Shaver, Jeremy; Tomaras, Georgia D.; Yates, Nicole L.; Ketchem, Randal R. Share Save
A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma Smith, Dirk; Helgason, Hannes; Sulem, Patrick; Bjornsdottir, Unnur Steina; Lim, Ai Ching; Sveinbjornsson, Gardar; Hasegawa, Haruki; Brown, Michael; Ketchem, Randal R.; Gavala, Monica; Garrett, Logan; Jonasdottir, Adalbjorg; Jonasdottir, Aslaug; Sigurdsson, Asgeir; Magnusson, Olafur T.; Eyjolfsson, Gudmundur I.; Olafsson, Isleifur; Onundarson, Pall Torfi; Sigurdardottir, Olof; Gislason, David; Gislason, Thorarinn; Ludviksson, Bjorn Runar; Ludviksdottir, Dora; Boezen, H. Marike; Heinzmann, Andrea; Krueger, Marcus; Porsbjerg, Celeste; Ahluwalia, Tarunveer S.; Waage, Johannes; Backer, Vibeke; Deichmann, Klaus A.; Koppelman, Gerard H.; Bonnelykke, Klaus; Bisgaard, Hans; Masson, Gisli; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel F.; Johnston, James A.; Jonsdottir, Ingileif; Stefansson, Kari Share Save
Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity-Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor-Binding Enhancement Henne, Kirk R.; Ason, Brandon; Howard, Monique; Wang, Wei; Sun, Jeonghoon; Higbee, Jared; Tang, Jie; Matsuda, Katherine C.; Xu, Ren; Zhou, Lei; Chan, Joyce C. Y.; King, Chadwick; Piper, Derek E.; Ketchem, Randal R.; Michaels, Mark Leo; Jackson, Simon M.; Retter, Marc W. Share Save
ADAM8 as a drug target in pancreatic cancer Schlomann, Uwe; Koller, Garrit; Conrad, Catharina; Ferdous, Taheera; Golfi, Panagiota; Garcia, Adolfo Molejon; Hofling, Sabrina; Parsons, Maddy; Costa, Patricia; Soper, Robin; Bossard, Maud; Hagemann, Thorsten; Roshani, Rozita; Sewald, Norbert; Ketchem, Randal R.; Moss, Marcia L.; Rasmussen, Fred H.; Miller, Miles A.; Lauffenburger, Douglas A.; Tuveson, David A.; Nimsky, Christopher; Bartsch, Jorg W. Share Save
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In Vivo Crystallization of Human IgG in the Endoplasmic Reticulum of Engineered Chinese Hamster Ovary (CHO) Cells Hasegawa, Haruki; Wendling, John; He, Feng; Trilisky, Egor; Stevenson, Riki; Franey, Heather; Kinderman, Francis; Li, Gary; Piedmonte, Deirdre Murphy; Osslund, Timothy; Shen, Min; Ketchem, Randal R. Share Save
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A Central Nervous System-Restricted Isoform of the Interleukin-1 Receptor Accessory Protein Modulates Neuronal Responses to Interleukin-1 Smith, Dirk E.; Lipsky, Brian P.; Russell, Chris; Ketchem, Randal R.; Kirchner, Jacqueline; Hensley, Kelly; Huang, Yangyang; Friedman, Wilma J.; Boissonneault, Vincent; Plante, Marie-Michele; Rivest, Serge; Sims, John E. Share Save
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