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Luis Concha-Marambio

r&d department
H-index:23
Citation Count:3,099

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Regulatory endorsement for the application of α-synuclein seed amplification assay as a susceptibility and risk biomarker for clinical trials targeting synucleinopathies

α-突触核蛋白种子扩增试验作为针对突触核蛋白病的易感性和风险生物标志物的临床研究适用性监管认可

Journal of Parkinsons Disease
IF5
2026-07-240
PRE
Diane Stephenson; Luis Concha-Marambio; Tom Lanz; Kalpana Merchant; Kathrin Brockmann; Nicholas King; Laura Carrillo; Anne Pedata; Harsha Kocherla; Samantha J Hutten;
Seed amplification of MSA alpha-synuclein aggregates preserves the biological and structural properties of brain-derived aggregates

MSA α-突触核蛋白聚集物的种子扩增保留了脑源性聚集物的生物学和结构特性

Nature Communications
IF15.7
2025-12-100
OA
Fei Wang; Victor Banerjee; Carla Barria; Santiago Ramirez; Tyler Allison; Damian Gorski; Haley Evans; Quynh Nguyen; Danielle Harrison; Rabab Al-Lahham; Nicole De Gregorio Carbonell; Michelle Pinho; Sanne Kaalund; Jonas Folke; Susana Aznar; Luis Concha-Marambio; Mohd Ishtikhar; Venkata KPS Mallampalli; Sandra Pritzkow; Mohammad Shahnawaz; Matthew L. Baker; Irina Serysheva; Claudio Soto
Comparison of Two α-Synuclein Seed Amplification Assays for Discrimination of Parkinson Disease and Atypical Parkinsonism

两种α-突触核蛋白种子放大检测法的比较：用于区分帕金森病和非典型帕金森综合征

Movement Disorders
IF7.6
2025-08-200
OAAI
Marcello Rossi PhD; Carly M. Farris MSc; Simone Baiardi MD, PhD; Giulia Giannini MD, PhD; Franco Magliocchetti MSc; Luisa Sambati MD, PhD; Yihua Ma MSc; Erica Vittoriosi MSc; Giovanna Calandra-Buonaura MD, PhD; Luis Concha-Marambio PhD; Piero Parchi MD, PhD
Staged Screening Identifies People with Biomarkers Related to Neuronal Alpha-Synuclein Disease
ANNALS OF NEUROLOGY
IF7.7
2024-12-240
OAAI
Brown, Ethan G.; Chahine, Lana M.; Siderowf, Andrew; Gochanour, Caroline; Kurth, Ryan; Marshall, Micah J.; Caspell-Garcia, Chelsea; Brumm, Michael C.; Stanley Jr, Craig E.; Korell, Monica; Mcmahon, Bridget; Kuhl, Maggie; Fabrizio, Kimberly; Heathers, Laura; Concha-Marambio, Luis; Soto, Claudio; Chowdhury, Sohini; Coffey, Christopher S.; Foroud, Tatiana M.; Simuni, Tanya; Marek, Kenneth; Tanner, Caroline M.; Parkinson Progression Marker Initiative
Association of CSF α-synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer's Disease Neuroimaging Initiative study

CSF α-突触核蛋白种子扩增检测阳性与疾病进展和认知下降的关联: 一项纵向阿尔茨海默病神经影像学倡议研究

ALZHEIMERS & DEMENTIA
IF11.1
2024-10-200
OA
Tosun, Duygu; Hausle, Zachary; Thropp, Pamela; Concha-Marambio, Luis; Lamoureux, Jennifer; Lebovitz, Russ; Shaw, Leslie M.; Singleton, Andrew B.; Weiner, Michael W.; Blauwendraat, Cornelis
Neuronal alpha-Synuclein Disease integrated staging system performance in PPMI, PASADENA, and SPARK baseline cohorts

PPMI，帕萨迪纳和SPARK基线队列中的神经元 α-突触核蛋白疾病综合分期系统性能

NPJ PARKINSONS DISEASE
IF8.2
2024-09-270
OAAI
Dam, Tien; Pagano, Gennaro; Brumm, Michael C.; Gochanour, Caroline; Poston, Kathleen L.; Weintraub, Daniel; Chahine, Lana M.; Coffey, Christopher; Tanner, Caroline M.; Kopil, Catherine M.; Xiao, Yuge; Chowdhury, Sohini; Concha-Marambio, Luis; Dibiaso, Peter; Foroud, Tatiana; Frasier, Mark; Jennings, Danna; Kieburtz, Karl; Merchant, Kalpana; Mollenhauer, Brit; Montine, Thomas J.; Nudelman, Kelly; Seibyl, John; Sherer, Todd; Singleton, Andrew; Stephenson, Diane; Stern, Matthew; Soto, Claudio; Tolosa, Eduardo; Siderowf, Andrew; Dunn, Billy; Simuni, Tanya; Marek, Kenneth; Parkinsons Progression Markers Initiative, Caroline
Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial
NATURE MEDICINE
IF50
2024-06-203
OAAI
Eijsvogel, Pepijn; Misra, Pinaki; Concha-Marambio, Luis; Boyd, Justin D.; Ding, Shuang; Fedor, Lauren; Hsieh, Yueh-Ting; Sun, Yu Shuang; Vroom, Madeline M.; Farris, Carly M.; Ma, Yihua; de Kam, Marieke L.; Radanovic, Igor; Vissers, Maurits F. J. M.; Mirski, Dario; Shareghi, Ghazal; Shahnawaz, Mohammad; Singer, Wolfgang; Kremer, Philip; Groeneveld, Geert Jan; Yu, Hui Jing; Dodart, Jean-Cosme
Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort

行为神经病学尸检队列中脑脊液 α-突触核蛋白种子扩增试验的临床病理相关性

ALZHEIMERS & DEMENTIA
IF11.1
2024-03-277
OAAI
Samudra, Niyatee; Fischer, D. Luke; Lenio, Steven; Lago, Argentina Lario; Ljubenkov, Peter A.; Rojas, Julio C.; Seeley, William W.; Spina, Salvatore; Staffaroni, Adam M.; Tablante, Jonathan; Wekselman, Fattin; Lamoureux, Jennifer; Concha-Marambio, Luis; Grinberg, Lea T.; Boxer, Adam L.; VandeVrede, Lawren
Investigating alpha-synuclein co-pathology in Alzheimer's disease bymeans of cerebrospinal fluid alpha-synuclein seed amplification assay

通过脑脊液 α-突触核蛋白种子扩增测定研究阿尔茨海默氏病中的 α-突触核蛋白共病理

ALZHEIMERS & DEMENTIA
IF11.1
2024-02-0714
OA
Bellomo, Giovanni; Toja, Andrea; Paoletti, Federico Paolini; Ma, Yihua; Farris, Carly M.; Gaetani, Lorenzo; Salvadori, Nicola; Chiasserini, Davide; LidiaWojdala, Anna; Concha-Marambio, Luis; Parnetti, Lucilla
Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays
MOLECULAR NEURODEGENERATION
IF17.5
2023-04-0119
OAAI
Bellomo, Giovanni; Paciotti, Silvia; Concha-Marambio, Luis; Rizzo, Domenico; Wojdala, Anna Lidia; Chiasserini, Davide; Gatticchi, Leonardo; Cerofolini, Linda; Giuntini, Stefano; De Luca, Chiara Maria Giulia; Ma, Yihua; Farris, Carly M.; Pieraccini, Giuseppe; Bologna, Sara; Filidei, Marta; Ravera, Enrico; Lelli, Moreno; Moda, Fabio; Fragai, Marco; Parnetti, Lucilla; Luchinat, Claudio
Accurate Detection of α-Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson's Disease in the DeNovo Parkinson (DeNoPa) Cohort
MOVEMENT DISORDERS
IF7.6
2023-02-1336
OAAI
Concha-Marambio, Luis; Weber, Sandrina; Farris, Carly M.; Dakna, Mohammed; Lang, Elisabeth; Wicke, Tamara; Ma, Yihua; Starke, Maritta; Ebentheuer, Jens; Sixel-Doering, Friederike; Muntean, Maria-Lucia; Schade, Sebastian; Trenkwalder, Claudia; Soto, Claudio; Mollenhauer, Brit

Research Directions

The data has not been retrieved yet.
C
Claudio Soto
H-index:89Papers:366Citations:3.0万
C
Carly M. Farris
H-index:12Papers:30Citations:1,718
Y
Yihua Ma
H-index:10Papers:32Citations:1,226
S
Sandra Pritzkow
H-index:16Papers:36Citations:3,117
F
Fabio Moda
H-index:33Papers:139Citations:3,574
S
Samantha J. Hutten
H-index:32Papers:54Citations:3,760
U
Un Jung Kang
H-index:66Papers:195Citations:1.3万
K
Kalpana Merchant
H-index:48Papers:155Citations:7,625
D
Davide Chiasserini
H-index:40Papers:145Citations:6,067
C
Chelsea Caspell‐Garcia
H-index:32Papers:76Citations:4,924