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A rare variant in GPR156 associated with depression in a Mennonite pedigree causes habenula hyperactivity and stress sensitivity in mice Millera, Bradley R.; Gonzaga-Jaureguic, Claudia; Brigattie, Karlla W.; de Jonga, Job; Breeseg, Robert S.; Ko, Seungyeon; Puffenbergere, Erik G.; Van Houtc, Cristopher; Younge, Millie; Lunah, Victor M.; Staplesc, Jeffrey; First, Michael B.; Gregoirea, Hilledna J.; Dworka, Andrew J.; Pefanisg, Evangelos; Mccarthyc, Shane; Brydges, Susannah; Rojasg, Jose; Yec, Bin; Stahlc, Eli; Di Gioiac, Silvio Alessandro; Hena, Rene; Elwoodi, Kevin; Rosoklijaa, Gorazd; Lic, Dadong; Mellisg, Scott; Careyi, David; Crollg, Susan D.; Overtonc, John D.; Macdonaldg, Lynn E.; Economidesc, Aris N.; Shuldinerc, Alan R.; Chuhmaf, Nao; Rayportf, Stephen; Aminj, Najaf; Kushnera, Steven A.; Haberg, Nicole Alessandri-; Markx, Sander; Strauss, Kevin A. Share Save
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Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings Chim, Shek Man; Howell, Kristen; Dronzek, John; Wu, Weizhen; Van Hout, Cristopher; Ferreira, Manuel A. R.; Ye, Bin; Li, Alexander; Brydges, Susannah; Arunachalam, Vinayagam; Marcketta, Anthony; Locke, Adam E.; Bovijn, Jonas; Verweij, Niek; De, Tanima; Lotta, Luca; Mitnaul, Lyndon; LeBlanc, Michelle; Carey, David J.; Melander, Olle; Shuldiner, Alan; Karalis, Katia; Economides, Aris N.; Nistala, Harikiran Share Save
Characterization of flare-ups and impact of garetosmab in adults with fibrodysplasia ossificans progressiva: a post hoc analysis of the randomized, double-blind, placebo-controlled LUMINA-1 trial Keen, Richard; Dahir, Kathryn M.; McGinniss, Jennifer; Sanchez, Robert J.; Mellis, Scott; Economides, Aris N.; Di Rocco, Maja; Orcel, Philippe; Roux, Christian; Tabarkiewicz, Jacek; Bachiller-Corral, Javier; Cheung, Angela M.; Al Mukaddam, Mona; Mohammadi, Kusha; Gu, Jing; Srinivasan, Dushyanth; Trotter, Dinko Gonzalez; Eekhoff, E. Marelise W.; Kaplan, Frederick S.; Pignolo, Robert J. Share Save
Genetic risk factors for COVID-19 and influenza are largely distinct Kosmicki, Jack A.; Marcketta, Anthony; Sharma, Deepika; Di Gioia, Silvio Alessandro; Batista, Samantha; Yang, Xiao-Man; Tzoneva, Gannie; Martinez, Hector; Sidore, Carlo; Kessler, Michael D.; Horowitz, Julie E.; Roberts, Genevieve H. L.; Justice, Anne E.; Banerjee, Nilanjana; Coignet, Marie V.; Leader, Joseph B.; Park, Danny S.; Lanche, Rouel; Maxwell, Evan; Knight, Spencer C.; Bai, Xiaodong; Guturu, Harendra; Baltzell, Asher; Girshick, Ahna R.; McCurdy, Shannon R.; Partha, Raghavendran; Mansfield, Adam J.; Turissini, David A.; Zhang, Miao; Mbatchou, Joelle; Watanabe, Kyoko; Verma, Anurag; Sirugo, Giorgio; Ritchie, Marylyn D.; Salerno, William J.; Shuldiner, Alan R.; Rader, Daniel J.; Mirshahi, Tooraj; Marchini, Jonathan; Overton, John D.; Carey, David J.; Habegger, Lukas; Reid, Jeffrey G.; Economides, Aris; Kyratsous, Christos; Karalis, Katia; Baum, Alina; Cantor, Michael N.; Rand, Kristin A.; Hong, Eurie L.; Ball, Catherine A.; Siminovitch, Katherine; Baras, Aris; Abecasis, Goncalo R.; Ferreira, Manuel A. R. Share Save
Skeletal phenotype amelioration in mucopolysaccharidosis VI requires intervention at the earliest stages of postnatal development Hwang-Wong, Elizabeth; Amar, Gabrielle; Das, Nanditha; Zhang, Xiaoli; Aaron, Nina; Gale, Kirsten; Rothman, Nyanza; Fante, Massimo; Baik, Andrew; Bhargava, Ajay; Fricker, Arun; Mcalister, Michelle; Rabinowitz, Jeremy; Lees-Shepard, John; Nannuru, Kalyan; Economides, Aris N.; Cygnar, Katherine D. Share Save
Garetosmab in fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial Di Rocco, Maja; Forleo-Neto, Eduardo; Pignolo, Robert J.; Keen, Richard; Orcel, Philippe; Funck-Brentano, Thomas; Roux, Christian; Kolta, Sami; Madeo, Annalisa; Bubbear, Judith S.; Tabarkiewicz, Jacek; Szczepanek, Malgorzata; Bachiller-Corral, Javier; Cheung, Angela M.; Dahir, Kathryn M.; Botman, Esmee; Raijmakers, Pieter G.; Mukaddam, Mona Al; Tile, Lianne; Portal-Celhay, Cynthia; Sarkar, Neena; Hou, Peijie; Musser, Bret J.; Boyapati, Anita; Mohammadi, Kusha; Mellis, Scott J.; Rankin, Andrew J.; Economides, Aris N.; Trotter, Dinko Gonzalez; Herman, Gary A.; O'Meara, Sarah J.; Delgizzi, Richard; Weinreich, David M.; Yancopoulos, George D.; Eekhoff, E. Marelise W.; Kaplan, Frederick S. Share Save
Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis Zhou, Sirui; Sosina, Olukayode A.; Bovijn, Jonas; Laurent, Laetitia; Sharma, Vasundhara; Akbari, Parsa; Forgetta, Vincenzo; Jiang, Lai; Kosmicki, Jack A.; Banerjee, Nilanjana; Morris, John A.; Oerton, Erin; Jones, Marcus; LeBlanc, Michelle G.; Idone, Vincent; Overton, John D.; Reid, Jeffrey G.; Cantor, Michael; Abecasis, Goncalo R.; Goltzman, David; Greenwood, Celia M. T.; Langenberg, Claudia; Baras, Aris; Economides, Aris N.; Ferreira, Manuel A. R.; Hatsell, Sarah; Ohlsson, Claes; Richards, J. Brent; Lotta, Luca A. Share Save
Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice Adam, Rene C.; Pryce, Dwaine S.; Lee, Joseph S.; Zhao, Yuanqi; Mintah, Ivory J.; Min, Soo; Halasz, Gabor; Mastaitis, Jason; Atwal, Gurinder S.; Aykul, Senem; Idone, Vincent; Economides, Aris N.; Lotta, Luca A.; Murphy, Andrew J.; Yancopoulos, George D.; Sleeman, Mark W.; Gusarova, Viktoria Share Save
Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors Kotsaris, Georgios; Qazi, Taimoor H. H.; Bucher, Christian H. H.; Zahid, Hafsa; Poehle-Kronawitter, Sophie; Ugorets, Vladimir; Jarassier, William; Boerno, Stefan; Timmermann, Bernd; Giesecke-Thiel, Claudia; Economides, Aris N. N.; Le Grand, Fabien; Vallecillo-Garcia, Pedro; Knaus, Petra; Geissler, Sven; Stricker, Sigmar Share Save
Antibodies to sclerostin or G-CSF receptor partially eliminate bone or marrow adipocyte loss, respectively, following vertical sleeve gastrectomy Li, Ziru; Qiu, Kevin; Zhao, Jingtong; Granger, Katrina; Yu, Hui; Lewis, Alfor G.; Myronovych, Andriy; Toure, Mouhamadoul H.; Hatsell, Sarah J.; Economides, Aris N.; Seeley, Randy J.; MacDougald, Ormond A. Share Save
Conditional activation of Akt in adult skeletal muscle induces rapid hypertrophy Lai, KMV; Gonzalez, M; Poueymirou, WT; Kline, WO; Na, EQ; Zlotchenko, E; Stitt, TN; Economides, AN; Yancopoulos, GD; Glass, DJ Share Save
A neuronal action of sirtuin 1 suppresses bone mass in young and aging mice Luo, Na; Mosialou, Ioanna; Capulli, Mattia; Bisikirska, Brygida; Lin, Chyuan-Sheng; Huang, Yung-Yu; Shyu, Peter T.; Guo, X. Edward; Economides, Aris; Mann, J. John; Kousteni, Stavroula Share Save
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Germline Mutations in CIDEB and Protection against Liver Disease Verweij, N.; Haas, M. E.; Nielsen, J. B.; Sosina, O. A.; Kim, M.; Akbari, P.; De, T.; Hindy, G.; Bovijn, J.; Persaud, T.; Miloscio, L.; Germino, M.; Panagis, L.; Watanabe, K.; Mbatchou, J.; Jones, M.; LeBlanc, M.; Balasubramanian, S.; Lammert, C.; Enhorning, S.; Melander, O.; Carey, D. J.; Still, C. D.; Mirshahi, T.; Rader, D. J.; Parasoglou, P.; Walls, J. R.; Overton, J. D.; Reid, J. G.; Economides, A.; Cantor, M. N.; Zambrowicz, B.; Murphy, A. J.; Abecasis, G. R.; Ferreira, M. A. R.; Smagris, E.; Gusarova, V; Sleeman, M.; Yancopoulos, G. D.; Marchini, J.; Kang, H. M.; Karalis, K.; Shuldiner, A. R.; Della Gatta, G.; Locke, A. E.; Baras, A.; Lotta, L. A. Share Save
Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1 Aykul, Senem; Huang, Lily; Wang, Lili; Das, Nanditha M.; Reisman, Sandra; Ray, Yonaton; Zhang, Qian; Rothman, Nyanza; Nannuru, Kalyan C.; Kamat, Vishal; Brydges, Susannah; Troncone, Luca; Johnsen, Laura; Yu, Paul B.; Fazio, Sergio; Lees-Shepard, John; Schutz, Kevin; Murphy, Andrew J.; Economides, Aris N.; Idone, Vincent; Hatsell, Sarah J. Share Save
Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit Jaaro-Peled, Hanna; Kumar, Sunil; Hughes, Dalton; Sumitomo, Akiko; Kim, Sun-Hong; Zoubovsky, Sandra; Hirota-Tsuyada, Yuki; Zala, Diana; Bruyere, Julie; Katz, Brittany M.; Huang, Beverly; Flores, Rafael; Narayan, Soumya; Hou, Zhipeng; Economides, Aris N.; Hikida, Takatoshi; Wetsel, William C.; Deisseroth, Karl; Mori, Susumu; Brandon, Nicholas J.; Tanaka, Motomasa; Ishizuka, Koko; Houslay, Miles D.; Saudou, Frederic; Dzirasa, Kafui; Sawa, Akira; Tomoda, Toshifumi Share Save
Defining phenotype reversibility in lysosomal disease: Leveraging a COIN model in mucopolysaccharidosis type VI (MPS VI) Hwang-Wong, Elizabeth; Amar, Gabrielle; Das, Nanditha; Zhang, Xiaoli; Rothman, Nyanza; Calafati, Philip; Aaron, Nina; Gale, Kirsten; Fante, Massimo; Lees-Shepard, John; Nannuru, Kalyan; Baik, Andrew; Economides, Aris; Cygnar, Katherine Share Save
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