Not logged in Structure-Based Discovery of Potent and Selective Small-Molecule α5β1 Integrin Inhibitors for Asthma Therapy Beresis, Richard; Sundaram, Aparna; Jo, Hyunil; Adler, Marc; Wang, Zheng; Mcintosh, Joel; Yeon, Seul Ki; Huang, Qiuya; Ngo, Grace; Sheppard, Dean; Degrado, William F. Share Save
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Myeloid-mesenchymal crosstalk drives ARG1dependent profibrotic metabolism via ornithine in lung fibrosis Yadav, Preeti; Ortega, Javier Gomez; Dabral, Prerna; Tamaki, Whitney; Chien, Charles; Chang, Kai-Chun; Biswas, Nivedita; Pan, Sixuan; Nilsson, Julia; Yin, Xiaoyang; Bhattacharyya, Aritra; Boostanpour, Kaveh; Jujaray, Tanay; Wang, Jasper T.; Tsukui, Tatsuya; Molina, Christopher J.; Auyeung, Vincent C.; Sheppard, Dean; Li, Baosheng; Maishan, Mazharul; Taenaka, Hiroki; Matthay, Michael A.; Muramatsu, Rieko; Maliskova, Lenka; Ghosh, Arnab; Eckalbar, Walter L.; Molofsky, Ari B.; Tamaki, Stanley J.; Bivona, Trever G.; Abate, Adam R.; Wagner, Allon; Pillai, Satish K.; Wolters, Paul J.; Tharp, Kevin M.; Bhattacharya, Mallar Share Save
Targeting TGFβ-mediated B cell suppression enhances anti-PD-1 efficacy in glioblastoma Hou, David; Wang, Si; Castro, Brandyn A.; Katz, Joshua L.; Dapash, Mark; Arrieta, Victor A.; Vazquez-Cervantes, Gustavo, I; Wan, Hanxiao; Billingham, Leah K.; Du, Rebecca; Murphy, Alina R.; Lopez-Rosas, Aurora; Han, Yu; Patel, Ronit, V; Chia, Tzu-Yi; Dmello, Crismita C.; Zhang, Peng; Sheppard, Dean; Sonabend, Adam M.; Miska, Jason M.; Lesniak, Maciej S.; Heiland, Dieter Henrik; Lee-Chang, Catalina Share Save
Pharmacologic inhibition of IRE1α-dependent decay protects alveolar epithelial identity and prevents pulmonary fibrosis in mice Auyeung, Vincent C.; Steinberg, Tavienne L.; Olivier, Alina; Suzuki, Luka; Moreno, Mary E.; Khan, Imran S.; Downey, Michael S.; Thamsen, Maike; Guo, Lu; Maly, Dustin J.; Backes, Bradley J.; Sheppard, Dean; Papa, Feroz R. Share Save
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Dual aVß8 Integrin and PD-1 Blockade Overcomes TGFβ-Mediated B-Cell Suppression to Enhance Anti-Tumor Immunity Hou, David; Wang, Si; Castro, Brandyn A.; Katz, Joshua L.; Dapash, Mark; Arrieta, Victor A.; Vazquez-Cervantes, Gustavo, I; Wan, Hanxiao; Billingham, Leah K.; Du, Rebecca; Murphy, Alina R.; Lopez-Rosas, Aurora; Han, Yu; Patel, Ronit, V; Chia, Tzu-Yi; Dmello, Crismita C.; Zhang, Peng; Sheppard, Dean; Sonabend, Adam M.; Miska, Jason M.; Lesniak, Maciej S.; Heiland, Dieter Henrik; Lee-Chang, Catalina Share Save
Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity McKinsey, Gabriel L.; Santander, Nicolas; Zhang, Xiaoming; Kleemann, Kilian L.; Tran, Lauren; Katewa, Aditya; Conant, Kaylynn; Barraza, Matthew; Waddell, Kian; Lizama, Carlos O.; La Russa, Marie; Koo, Ji Hyun; Lee, Hyunji; Mukherjee, Dibyanti; Paidassi, Helena; Anton, E. S.; Atabai, Kamran; Sheppard, Dean; Butovsky, Oleg; Arnold, Thomas D. Share Save
ATF4 drives regulatory T cell functional specification in homeostasis and obesity Wang, Ke; Farrell, Andrea; Zhou, Enchen; Qin, Houji; Zeng, Zixuan; Zhou, Kailun; Rocha, Karina; Zhang, Dinghong; Wang, Gaowei; Atakilit, Amha; Sheppard, Dean; Lu, Li-Fan; Jin, Chunyu; Ying, Wei Share Save
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An in vivo screening platform identifies senolytic compounds that target p16 INK4a+fibroblasts in lung fibrosis Lee, Jin Young; Reyes, Nabora S.; Ravishankar, Supriya; Zhou, Minqi; Krasilnikov, Maria; Ringler, Christian; Pohan, Grace; Wilson, Chris; Ang, Kenny Kean-Hooi; Wolters, Paul J.; Tsukui, Tatsuya; Sheppard, Dean; Arkin, Michelle R.; Peng, Tien Share Save
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Challenges and Opportunities for Commercializing Technologies in the Pulmonary Arena An Official American Thoracic Society Report Vukmirovic, Milica; Benam, Kambez H.; Rose, Jason J.; Turner, Scott; Magin, Chelsea M.; Lagares, David; Cohen, Alan H.; Kaminski, Naftali; Hirota, Jeremy A.; Maher, Toby M.; Konigshoff, Melanie; Mallampalli, Rama K.; Sheppard, Dean; Tarran, Robert; Gomer, Richard H.; Kenyon, Nicholas J.; Morris, David; Hobbie, Silke; Raju, S. Vamsee; Petrache, Irina; Watkins, Timothy; Kumar, Rishav; Lam, Wilbur A.; Sherer, Todd; Hecker, Louise Share Save
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints Yin, Zhuoran; Rosenzweig, Neta; Kleemann, Kilian L.; Zhang, Xiaoming; Brandao, Wesley; Margeta, Milica A.; Schroeder, Caitlin; Sivanathan, Kisha N.; Silveira, Sebastian; Gauthier, Christian; Mallah, Dania; Pitts, Kristen M.; Durao, Ana; Herron, Shawn; Shorey, Hannah; Cheng, Yiran; Barry, Jen-Li; Krishnan, Rajesh K.; Wakelin, Sam; Rhee, Jared; Yung, Anthony; Aronchik, Michael; Wang, Chao; Jain, Nimansha; Bao, Xin; Gerrits, Emma; Brouwer, Nieske; Deik, Amy; Tenen, Daniel G.; Ikezu, Tsuneya; Santander, Nicolas G.; Mckinsey, Gabriel L.; Baufeld, Caroline; Sheppard, Dean; Krasemann, Susanne; Nowarski, Roni; Eggen, Bart J. L.; Clish, Clary; Tanzi, Rudolph E.; Madore, Charlotte; Arnold, Thomas D.; Holtzman, David M.; Butovsky, Oleg Share Save
An immune-based tool platform for in vivo cell clearance Zhang, Jieqiong; Tsukui, Tatsuya; Wu, Xiumin; Brito, Alyssa; Trumble, John Maxwell; Caraballo, Juan C.; Allen, Greg M.; Zavala-Solorio, Jose; Zhang, Chunlian; Paw, Jonathan; Lim, Wendell A.; Geng, Jiefei; Kutskova, Yuliya; Freund, Adam; Kolumam, Ganesh; Sheppard, Dean; Cohen, Robert L. Share Save
An integrated cell atlas of the lung in health and disease Sikkema, Lisa; Ramirez-Suastegui, Ciro; Strobl, Daniel C.; Gillett, Tessa E.; Zappia, Luke; Madissoon, Elo; Markov, Nikolay S.; Zaragosi, Laure-Emmanuelle; Ji, Yuge; Ansari, Meshal; Arguel, Marie-Jeanne; Apperloo, Leonie; Banchero, Martin; Becavin, Christophe; Berg, Marijn; Chichelnitskiy, Evgeny; Chung, Mei-i; Collin, Antoine; Gay, Aurore C. A.; Gote-Schniering, Janine; Kashani, Baharak Hooshiar; Inecik, Kemal; Jain, Manu; Kapellos, Theodore S.; Kole, Tessa M.; Leroy, Sylvie; Mayr, Christoph H.; Oliver, Amanda J.; von Papen, Michael; Peter, Lance; Taylor, Chase J.; Walzthoeni, Thomas; Xu, Chuan; Bui, Linh T.; De Donno, Carlo; Dony, Leander; Faiz, Alen; Guo, Minzhe; Gutierrez, Austin J.; Heumos, Lukas; Huang, Ni; Ibarra, Ignacio L.; Jackson, Nathan D.; Murthy, Preetish Kadur Lakshminarasimha; Lotfollahi, Mohammad; Tabib, Tracy; Talavera-Lopez, Carlos; Travaglini, Kyle J.; Wilbrey-Clark, Anna; Worlock, Kaylee B.; Yoshida, Masahiro; van den Berge, Maarten; Bosse, Yohan; Desai, Tushar J.; Eickelberg, Oliver; Kaminski, Naftali; Krasnow, Mark A.; Lafyatis, Robert; Nikolic, Marko Z.; Powell, Joseph E.; Rajagopal, Jayaraj; Rojas, Mauricio; Rozenblatt-Rosen, Orit; Seibold, Max A.; Sheppard, Dean; Shepherd, Douglas P.; Sin, Don D.; Timens, Wim; Tsankov, Alexander M.; Whitsett, Jeffrey; Xu, Yan; Banovich, Nicholas E.; Barbry, Pascal; Duong, Thu Elizabeth; Falk, Christine S.; Meyer, Kerstin B.; Kropski, Jonathan A.; Pe'er, Dana; Schiller, Herbert B.; Tata, Purushothama Rao; Schultze, Joachim L.; Teichmann, Sara A.; Misharin, Alexander, V; Nawijn, Martijn C.; Luecken, Malte D.; Theis, Fabian J.; Chen, Yuexin; Hagood, James S.; Agami, Ahmed; Horvath, Peter; Lundeberg, Joakim; Marquette, Charles-Hugo; Pryhuber, Gloria; Samakovlis, Chistos; Sun, Xin; Ware, Lorraine B.; Zhang, Kun Share Save
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