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Satoshi Koyama

massachusetts general hospital

41H-index
286Paper Count
6.8KCitation Count
Published Papers 106
Publication Date
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A Bayesian framework for longitudinal EHR and genetic discovery
errNature
IF48.5
err2026-07-15
err0
errOAAI
errSarah M. Urbut; Yi Ding; Tetsushi Nakao; Satoshi Koyama; Anika Misra; Xilin Jiang; Achyutha Harish; Leslie Gaffney; Whitney E. Hornsby; Jordan W. Smoller; Alexander Gusev; Pradeep Natarajan; Giovanni Parmigiani
errShare
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Exome-wide association study of blood lipids in 1,158,017 individuals from diverse populations
errNature Genetics
IF29
err2026-05-25
err0
errOAAI
errSatoshi Koyama; Zhi Yu; Seung Hoan Choi; Sean J. Jurgens; Margaret Sunitha Selvaraj; Derek Klarin; Jennifer E. Huffman; Shoa L. Clarke; Selena K. Zhang; Michael N. Trinh; Akshaya Ravi; Jacqueline S. Dron; Catherine Spinks; Ida Surakka; Aarushi Bhatnagar; Kim Lannery; Whitney Hornsby; Scott M. Damrauer; Kyong-Mi Chang; Julie A. Lynch; Themistocles L. Assimes; Philip S. Tsao; Daniel J. Rader; Kelly Cho; Gina M. Peloso; Patrick T. Ellinor; Yan V. Sun; Peter W. F. Wilson; Pradeep Natarajan
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An integrated germline and somatic genomic model for coronary artery disease
errNature Communications
IF15.7
err2026-03-26
err0
errOAAI
errXiong Yang; Min Seo Kim; Xinyu Zhu; Md Mesbah Uddin; Tetsushi Nakao; So Mi Jemma Cho; Satoshi Koyama; Tingfeng Xu; Laurens F. Reeskamp; Rufan Zhang; Zhaoqi Liu; Yunga A; Paul S. de Vries; Ramachandran S. Vasan; Eric Boerwinkle; Alanna C. Morrison; Bruce M. Psaty; Russell P. Tracy; Susan R. Heckbert; Michael H. Cho; Jeong H. Yun; Nicholette D. Palmer; Donald W. Bowden; Joanne M. Murabito; Daniel Levy; Nancy L. Heard-Costa; George T. O’Connor; Lewis C. Becker; Brian G. Kral; Lisa R. Yanek; Laura M. Raffield; Bertha Hidalgo; Jerome I. Rotter; Stephen S. Rich; Kent D. Taylor; Wendy S. Post; Charles Kooperberg; Alexander P. Reiner; Braxton D. Mitchell; Sharon L. R. Kardia; Jennifer A. Smith; Patricia A. Peyser; Lawrence F. Bielak; Dong Keon Yon; Hong-Hee Won; Donna K. Arnett; Albert V. Smith; Stacey B. Gabriel; Patrick T. Ellinor; Pradeep Natarajan; Minxian Wang; Akl C. Fahed
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Genomic, phenomic and geographic associations of leukocyte telomere length in the United States
errNature Genetics
IF29
err2026-03-01
err0
errOAAI
errNakao, Tetsushi; Koyama, Satoshi; Truong, Buu; Uddin, Md Mesbah; Misra, Anika; Patel, Aniruddh P.; Bhatnagar, Aarushi; Viscosi, Victoria; Vlasschaert, Caitlyn; Bick, Alexander G.; Nelson, Christopher P.; Codd, Veryan; Samani, Nilesh J.; Hornsby, Whitney; Ellinor, Patrick T.; Natarajan, Pradeep
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Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction
errNature Genetics
IF29
err2025-12-19
err0
errOAAI
errAeron M. Small; Ta-Yu Yang; Shinsuke Itoh; Sébastien Thériault; Line Dufresne; Ryo Kurosawa; Issei Komuro; Koichi Matsuda; Ha My T. Vy; Eric H. Farber-Eger; Lauren Lee Shaffer; Kristin M. Boulier; Kristin M. Corey; Megan E. Ramaker; Fabien Laporte; Jean-Jacques Schott; Solena Le Scouarnec; Sasha A. Singh; Abhijeet R. Sonawane; Harry A. Smith; Nicholas Rafaels; Jonas Ghouse; Anna A. Raja; Sisse R. Ostrowski; Erik Sørensen; Christina Mikkelsen; Ole B. Pedersen; Christian Erikstrup; Henrik Ullum; Gardar Sveinbjornsson; Daniel F. Gudbjartsson; Erik Abner; Jiwoo Lee; Andrea Ganna; Ulrike Nowak-Göttl; Sarah Finer; Johannes Schumacher; Carlo Maj; Baravan Al-Kassou; Georg Nickenig; Teresa Trenkwalder; Martina Dreβen; Markus Krane; Markus M. Nöthen; Marta R. Moksnes; Ben M. Brumpton; Stacey Knight; Kirk U. Knowlton; Lincoln Nadauld; Radek Debiec; Muntaser D. Musameh; Peter S. Braund; Christopher P. Nelson; Tomasz Czuba; Olle Melander; Margaret Sunitha Selvaraj; Satoshi Koyama; Rohan Bhukar; Yunfeng Ruan; Johan Ljungberg; Scott M. Damrauer; Michael G. Levin; Andre Franke; Klaus Berger; Christian T. Ruff; Giorgio E. M. Melloni; Frederick K. Kamanu; Kaoru Ito; Ron Do; Ruth J. F. Loos; Heribert Schunkert; Quinn S. Wells; Svati H. Shah; Thierry Le Tourneau; David Messika-Zeitoun; Christopher Gignoux; Henning Bundgaard; Susanna C. Larsson; Karl Michaëlsson; Hilma Holm; Anna Helgadottir; Tonu Esko; David A. van Heel; Patrick Mathieu; Nilesh J. Samani; J. Gustav Smith; Stefan Söderberg; Daniel J. Rader; Nicholas A. Marston; Marc S. Sabatine; Bogdan Pasaniuc; Kelly Cho; Peter W. F. Wilson; Christopher J. O’Donnell; Kari Stefansson; Yohan Bossé; Elena Aikawa; James C. Engert; Gina M. Peloso; Pradeep Natarajan; George Thanassoulis
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errSave
Multitrait analyses identify genetic variants associated with aortic valve function and aortic stenosis risk
errNature Genetics
IF29
err2025-12-19
err0
errOAAI
errShinwan Kany; Joel T. Rämö; Cody Hou; Sean J. Jurgens; Shaan Khurshid; Victor Nauffal; Jonathan W. Cunningham; Emily S. Lau; Satoshi Koyama; Jennifer E. Ho; Jeffrey E. Olgin; Sammy Elmariah; Aarno Palotie; Mark E. Lindsay; Patrick T. Ellinor; James P. Pirruccello
errShare
errSave
Genetics and context for precision health in Greater Boston
errNature Communications
IF15.7
err2025-11-26
err0
errOAAI
errSatoshi Koyama; Ying Wang; Kaavya Paruchuri; Md Mesbah Uddin; So Mi J. Cho; Sarah M. Urbut; Yang Sui; Akl C. Fahed; Himani Kamineni; Sara Haidermota; Whitney E. Hornsby; Robert C. Green; Mark J. Daly; Benjamin M. Neale; Patrick T. Ellinor; Jordan W. Smoller; Susan A. Slaugenhaupt; Matthew S. Lebo; Elizabeth W. Karlson; Alicia R. Martin; Pradeep Natarajan
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errSave
Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population
errNature Communications
IF15.7
err2025-11-03
err0
errOAAI
errNobuyuki Enzan; Kazuo Miyazawa; Satoshi Koyama; Ryo Kurosawa; Hirotaka Ieki; Hiroki Yoshida; Fumie Takechi; Masashi Fukuyama; Ryosuke Osako; Kohei Tomizuka; Xiaoxi Liu; Kouichi Ozaki; Yoshihiro Onouchi; Koichi Matsuda; Yukihide Momozawa; Hiroyuki Aburatani; Yoichiro Kamatani; Takanori Yamaguchi; Hiroshi Akazawa; Koichi Node; Patrick T. Ellinor; Michael G. Levin; Scott M. Damrauer; Benjamin F. Voight; Jacob Joseph; Yan V. Sun; Chikashi Terao; Toshiharu Ninomiya; Issei Komuro; Kaoru Ito
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Population-scale Analysis Reveals Germline Loss of SERPING1 (C1-Inhibitor) is a Polyphenotypic Thrombotic Disorder
errBlood Advances
IF7.1
err2025-10-06
err0
errOAAI
errAlfonso Rodriguez Espada; Amelia K. Haj; Sean J. Jurgens; Harish Eswaran; Linda Sundler Bjorkman; Justine Ryu; Sharjeel Chaudry; Satoshi Koyama; Xin Wang; Seung Hoan Choi; Simone Sanna-Cherchi; Aleena Banerji; Joel T. Rämö; Patrick T. Ellinor; Steven P. Grover; Pavan K. Bendapudi
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Coagulation factor XII haploinsufficiency is protective against venous thromboembolism in a population-scale multidimensional analysis
errNature Communications
IF15.7
err2025-09-01
err0
errOAAI
errAmelia K. Haj; David S. Paul; Sean J. Jurgens; Harish Eswaran; Lu-Chen Weng; Justine Ryu; Alfonso Rodriguez Espada; Sharjeel Chaudhry; Louis M. Feingold; Kristen Burke; Satoshi Koyama; Xin Wang; Joyce Francis; Seung Hoan Choi; Nigel Mackman; Wolfgang Bergmeier; Alex Burgin; Joel T. Rämö; Patrick T. Ellinor; Steven P. Grover; Pavan K. Bendapudi
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errSave
Genomic Drivers of Coronary Artery Disease and Risk of Future Outcomes After Coronary Angiography
errJAMA NETWORK OPEN
IF9.7
err2025-01-21
err1
errOAAI
errSupriami, Kelvin; Urbut, Sarah M.; Tello-Ayala, Jose R.; Unlu, Ozan; Friedman, Samuel F.; Abou-Karam, Roukoz; Koyama, Satoshi; Uddin, Md Mesbah; Pomerantsev, Eugene; Lu, Michael T.; Honigberg, Michael C.; Aragam, Krishna G.; Doshi-Velez, Finale; Patel, Aniruddh P.; Ellinor, Patrick T.; Fahed, Akl C.
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Genetic Predisposition to Low-Density Lipoprotein Cholesterol and Incident Type 2 Diabetes
errJAMA CARDIOLOGY
IF14.1
err2025-01-15
err0
PREAI
errRavi, Akshaya; Koyama, Satoshi; Cho, So Mi Jemma; Haidermota, Sara; Hornsby, Whitney; Ellinor, Patrick T.
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errSave
Loss of function in protein Z (PROZ) is associated with increased risk of ischemic stroke in the UK Biobank
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2025-01-01
err0
PREAI
errHaj, Amelia K.; Ryu, Justine; Jurgens, Sean J.; Chaudhry, Sharjeel; Koyama, Satoshi; Wang, Xin; Choi, Seung Hoan; Hou, Cody; Sanna-Cherchi, Simone; Anderson, Christopher D.; Ellinor, Patrick T.; Bendapudi, Pavan K.
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Effects of Nutritional Support with a Leucine-Enriched Essential Amino Acid Supplement on Body Composition, Muscle Strength, and Physical Function in Stroke Patients Undergoing Rehabilitation
errNUTRIENTS
IF5
err2024-12-11
err0
errOAAI
errNakagawa, Naoki; Koyama, Satoshi; Maruyama, Keisuke; Maruyama, Jun-Ichi; Hasebe, Naoyuki
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Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience (NOV, 10.1038/s41588-024-01975-5, 2024)
errNATURE GENETICS
IF31.8
err2024-12-04
err0
errOAAI
errJurgens, Sean J.; Raemoe, Joel T.; Kramarenko, Daria R.; Wijdeveld, Leonoor F. J. M.; Haas, Jan; Chaffin, Mark D.; Garnier, Sophie; Gaziano, Liam; Weng, Lu-Chen; Lipov, Alex; Zheng, Sean L.; Henry, Albert; Huffman, Jennifer E.; Challa, Saketh; Ruehle, Frank; Verdugo, Carmen Diaz; Juarez, Christian Krijger; Kany, Shinwan; van Orsouw, Constance A.; Biddinger, Kiran; Poel, Edwin; Elliott, Amanda L.; Wang, Xin; Francis, Catherine; Ruan, Richard; Koyama, Satoshi; Beekman, Leander; Zimmerman, Dominic S.; Deleuze, Jean-Francois; Villard, Eric; Tregouet, David-Alexandre; Isnard, Richard; Boomsma, Dorret I.; de Geus, Eco J. C.; Tadros, Rafik; Pinto, Yigal M.; Wilde, Arthur A. M.; Hottenga, Jouke-Jan; Sinisalo, Juha; Niiranen, Teemu; Walsh, Roddy; Schmidt, Amand F.; Choi, Seung Hoan; Chang, Kyong-Mi; Tsao, Philip S.; Matthews, Paul M.; Ware, James S.; Lumbers, R. Thomas; van der Crabben, Saskia; Laukkanen, Jari; Palotie, Aarno; Amin, Ahmad S.; Charron, Philippe; Meder, Benjamin; Ellinor, Patrick T.; Daly, Mark; Aragam, Krishna G.; Bezzina, Connie R.
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Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience
errNATURE GENETICS
IF31.8
err2024-11-21
err1
errOAAI
errJurgens, Sean J.; Raemoe, Joel T.; Kramarenko, Daria R.; Wijdeveld, Leonoor F. J. M.; Haas, Jan; Chaffin, Mark D.; Garnier, Sophie; Gaziano, Liam; Weng, Lu-Chen; Lipov, Alex; Zheng, Sean L.; Henry, Albert; Huffman, Jennifer E.; Challa, Saketh; Ruehle, Frank; Verdugo, Carmen Diaz; Krijger Juarez, Christian; Kany, Shinwan; van Orsouw, Constance A.; Biddinger, Kiran; Poel, Edwin; Elliott, Amanda L.; Wang, Xin; Francis, Catherine; Ruan, Richard; Koyama, Satoshi; Beekman, Leander; Zimmerman, Dominic S.; Deleuze, Jean-Francois; Villard, Eric; Tregouet, David-Alexandre; Isnard, Richard; Boomsma, Dorret I.; de Geus, Eco J. C.; Tadros, Rafik; Pinto, Yigal M.; Wilde, Arthur A. M.; Hottenga, Jouke-Jan; Sinisalo, Juha; Niiranen, Teemu; Walsh, Roddy; Schmidt, Amand F.; Choi, Seung Hoan; Chang, Kyong-Mi; Tsao, Philip S.; Matthews, Paul M.; Ware, James S.; Lumbers, R. Thomas; van der Crabben, Saskia; Laukkanen, Jari; Palotie, Aarno; Amin, Ahmad S.; Charron, Philippe; Meder, Benjamin; Ellinor, Patrick T.; Daly, Mark; Aragam, Krishna G.; Bezzina, Connie R.
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Integrative proteomic analyses across common cardiac diseases yield mechanistic insights and enhanced prediction
errcardiovascular research
IF10.8
err2024-11-21
err0
errOAAI
errSchuermans, Art; Pournamdari, Ashley B.; Lee, Jiwoo; Bhukar, Rohan; Ganesh, Shriienidhie; Darosa, Nicholas; Small, Aeron M.; Yu, Zhi; Hornsby, Whitney; Koyama, Satoshi; Kooperberg, Charles; Reiner, Alexander P.; Januzzi, James L.; Honigberg, Michael C.; Natarajan, Pradeep
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Sex Influences Effects on Atherosclerosis in TET2-related Clonal Hematopoiesis of Indeterminate Potential and on Interleukin-1β Inhibition in Mice
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errVromman, Amelie; Nakao, Tetsushi; Fang, Shi; Dreyfuss, Jonathan; Pan, Hui; Vellarikkal, Shamsudheen; Gomes, Mariana Janini; Carter, Paul; Moscavitch, Samuel; Uddin, Md Mesbah; Cho, Mi; Xue, Liying; Honigberg, Michael; Paruchuri, Kaavya; Koyama, Satoshi; Zou, Roger; Ganesh, Shriienidhie; Zekavat, Seyedeh; Vlasschaert, Caitlyn; Sellar, Rob; McConkey, Marie; Yu, Zhi; Tesmenitsky, Yevgenia; Sausen, Grasiele; Shvartz, Eugenia; Wong, Waihay; Ruvkun, Victoria; Folco, Eduardo; Sukhova, Galina; Bick, Alexander; Ebert, Benjamin; Gupta, Rajat; Natarajan, Pradeep; Libby, Peter
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Machine Learning Uncovers the Contribution of Rare Genetic Variants and Enhances Risk Prediction for Coronary Artery Disease in the Japanese Population
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errIeki, Hirotaka; Ito, Kaoru; Zhang, Sai; Koyama, Satoshi; Miyazawa, Kazuo; Yoshida, Hiroki; Kurosawa, Ryo; Enzan, Nobuyuki; Ozaki, Kouichi; Onouchi, Yoshihiro; Kamatani, Yoichiro; Terao, Chikashi; Snyder, Michael; Komuro, Issei
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Multi-Omic Profiling of Adiposity Distribution Patterns
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errPan, Michael; Dron, Jacqueline; Schuermans, Art; Agrawal, Saaket; Fourman, Lindsay; Koyama, Satoshi; Hornsby, Whitney; Peloso, Gina; Natarajan, Pradeep
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Research Directions

No research directions
Co-authors
Cooperation Journals
P
Peter Libby
H-index: 227 · Papers: 1.2K
M
Mark J. Daly
H-index: 224 · Papers: 1.2K
K
Kāri Stefánsson
H-index: 219 · Papers: 1.2K
R
Ramachandran S. Vasan
H-index: 204 · Papers: 1.9K
E
Emelia J. Benjamin
H-index: 201 · Papers: 1.4K
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