Not logged in A human pan-disease blood atlas of the circulating proteome Alvez, Maria Bueno; Bergstrom, Sofia; Kenrick, Josefin; Johansson, Emil; Aberg, Mikael; Akyildiz, Murat; Altay, Ozlem; Skold, Hilda; Antonopoulos, Konstantinos; Apostolakis, Emmanouil; Balcioglu, Yasin Hasan; Bergstrom, Anna; Bergstrom, Goran; Bjorkander, Sophia; Brage, Suzanne Egyhazi; Brodin, Petter; Butler, Lynn; Cajander, Sara; Danielsson, Hanna; Dayangac, Murat; Dinler-Doganay, Gizem; Doganay, Levent; Enblad, Gunilla; Enblad, Malin; Fagerberg, Linn; Falck-Jones, Sara; Farnert, Anna; Forsberg, Mattias; Gonzalez, Laura; Gummesson, Anders; Gunnarsson, Karin; Gunnarsson, Iva; Gyllensten, Ulf; Hesselager, Goran; Hober, Andreas; Hoglund, Martin; Holmqvist, Marie; Horuluoglu, Begum; Hultgren, Rebecka; Iglesias, Maria Jesus; Janols, Helena; Johansson, Fredric; Johnsson, Anette; Klareskog, Lars; Kotol, David; Kull, Inger; Kvarnstrom, Marika; Lautenbach, Maximilian Julius; Liljedahl, Ulrika; Lindman, Henrik; Lindskog, Cecilia; Lipcsey, Miklos; Lundberg, Ingrid E.; Mardinoglu, Adil; Melen, Erik; Meng, Lingqi; Merritt, Anne-Sophie; Mulder, Jan; Nguyen, Mai Thi-Huyen; Nordlund, Jessica; Norrby-Teglund, Anna; Notarnicola, Antonella; Nowak, Piotr; Odeberg, Jacob; Oksvold, Per; Olsson, Tomas; Padyukov, Leonid; Pauksens, Karlis; Piehl, Fredrik; Pin, Elisa; Ponten, Fredrik; Rameika, Natallia; Reepalu, Anton; Roy, Joy; Schwenk, Jochen M.; Sen, Meltem; Siika, Antti; Simonson, Oscar E.; Sivertsson, Asa; Sjoblom, Tobias; Sjostedt, Evelina; Skoglund, Lovisa; Smed-Sorensen, Anna; Sonden, Klara; Sonnerborg, Anders; Stalberg, Karin; Stralin, Kristoffer; Sunden-Cullberg, Jonas; Sundling, Christopher; Sutantiwanichkul, Thanadol; Svedman, Fernanda Costa; Svensson, Mattias; Svenungsson, Elisabet; Lakshmikanth, Tadepally; Tran-Minh, Khue Hua; Turkez, Hasan; Unge, Christian; Venge, Per; Wahren-Herlenius, Marie; Woessmann, Jakob; Yang, Hong; Yesilkaya, Umit Haluk; Yuan, Meng; Zeybel, Mujdat; Zhang, Cheng; Zhong, Wen; Zwahlen, Martin; Von Feilitzen, Kalle; Nilsson, Peter; Edfors, Fredrik; Uhlen, Mathias Share Save
Detecting TP53 mutations in paired liquid and tissue biopsies from patients with high-grade serous ovarian carcinoma Widjaja, Amanda Olsson; Micallef, Peter; Lycke, Maria; Osterlund, Tobias; Santamaria, Manuel Luna; Lindberg, Julia Hedlund; Carlsson, Therese; Gyllensten, Ulf; Stahlberg, Anders; Ulfenborg, Benjamin; Linder, Anna; Sundfeldt, Karin Share Save
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Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits Keaton, Jacob M.; Kamali, Zoha; Xie, Tian; Vaez, Ahmad; Williams, Ariel; Goleva, Slavina B.; Ani, Alireza; Evangelou, Evangelos; Hellwege, Jacklyn N.; Yengo, Loic; Young, William J.; Traylor, Matthew; Giri, Ayush; Zheng, Zhili; Zeng, Jian; Chasman, Daniel I.; Morris, Andrew P.; Caulfield, Mark J.; Hwang, Shih-Jen; Kooner, Jaspal S.; Conen, David; Attia, John R.; Morrison, Alanna C.; Loos, Ruth J. F.; Kristiansson, Kati; Schmidt, Reinhold; Hicks, Andrew A.; Pramstaller, Peter P.; Nelson, Christopher P.; Samani, Nilesh J.; Risch, Lorenz; Gyllensten, Ulf; Melander, Olle; Riese, Harriette; Wilson, James F.; Campbell, Harry; Rich, Stephen S.; Psaty, Bruce M.; Lu, Yingchang; Rotter, Jerome I.; Guo, Xiuqing; Rice, Kenneth M.; Vollenweider, Peter; Sundstrom, Johan; Langenberg, Claudia; Tobin, Martin D.; Giedraitis, Vilmantas; Luan, Jian'an; Tuomilehto, Jaakko; Kutalik, Zoltan; Ripatti, Samuli; Salomaa, Veikko; Girotto, Giorgia; Trompet, Stella; Jukema, J. Wouter; van der Harst, Pim; Ridker, Paul M.; Giulianini, Franco; Vitart, Veronique; Goel, Anuj; Watkins, Hugh; Harris, Sarah E.; Deary, Ian J.; van der Most, Peter J.; Oldehinkel, Albertine J.; Keavney, Bernard D.; Hayward, Caroline; Campbell, Archie; Boehnke, Michael; Scott, Laura J.; Boutin, Thibaud; Mamasoula, Chrysovalanto; Jarvelin, Marjo-Riitta; Peters, Annette; Gieger, Christian; Lakatta, Edward G.; Cucca, Francesco; Hui, Jennie; Knekt, Paul; Enroth, Stefan; De Borst, Martin H.; Polasek, Ozren; Concas, Maria Pina; Catamo, Eulalia; Cocca, Massimiliano; Li-Gao, Ruifang; Hofer, Edith; Schmidt, Helena; Spedicati, Beatrice; Waldenberger, Melanie; Strachan, David P.; Laan, Maris; Teumer, Alexander; Dorr, Marcus; Gudnason, Vilmundur; Cook, James P.; Ruggiero, Daniela; Kolcic, Ivana; Boerwinkle, Eric; Traglia, Michela; Lehtimaki, Terho; Raitakari, Olli T.; Johnson, Andrew D.; Newton-Cheh, Christopher; Brown, Morris J.; Dominiczak, Anna F.; Sever, Peter J.; Poulter, Neil; Chambers, John C.; Elosua, Roberto; Siscovick, David; Esko, Tonu; Metspalu, Andres; Strawbridge, Rona J.; Laakso, Markku; Hamsten, Anders; Hottenga, Jouke-Jan; de Geus, Eco; Morris, Andrew D.; Palmer, Colin N. A.; Nolte, Ilja M.; Milaneschi, Yuri; Marten, Jonathan; Wright, Alan; Zeggini, Eleftheria; Howson, Joanna M. M.; O'Donnell, Christopher J.; Spector, Tim; Nalls, Mike A.; Simonsick, Eleanor M.; Liu, Yongmei; van Duijn, Cornelia M.; Butterworth, Adam S.; Danesh, John N.; Menni, Cristina; Wareham, Nicholas J.; Khaw, Kay-Tee; Sun, Yan V.; Wilson, Peter W. F.; Cho, Kelly; Visscher, Peter M.; Denny, Joshua C.; Levy, Daniel; Edwards, Todd L.; Munroe, Patricia B.; Snieder, Harold; Warren, Helen R. Share Save
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (vol 51, pg 481, 2019) Shrine, Nick; Guyatt, Anna L.; Erzurumluoglu, A. Mesut; Jackson, Victoria E.; Hobbs, Brian D.; Melbourne, Carl A.; Batini, Chiara; Fawcett, Katherine A.; Song, Kijoung; Sakornsakolpat, Phuwanat; Li, Xingnan; Boxall, Ruth; Reeve, Nicola F.; Obeidat, Ma'en; Zhao, Jing Hua; Wielscher, Matthias; Weiss, Stefan; Kentistou, Katherine A.; Cook, James P.; Sun, Benjamin B.; Zhou, Jian; Hui, Jennie; Karrasch, Stefan; Imboden, Medea; Harris, Sarah E.; Marten, Jonathan; Enroth, Stefan; Kerr, Shona M.; Surakka, Ida; Vitart, Veronique; Lehtimaeki, Terho; Allen, Richard J.; Bakke, Per S.; Beaty, Terri H.; Bleecker, Eugene R.; Bosse, Yohan; Brandsma, Corry-Anke; Chen, Zhengming; Crapo, James D.; Danesh, John; DeMeo, Dawn L.; Dudbridge, Frank; Ewert, Ralf; Gieger, Christian; Gulsvik, Amund; Hansell, Anna L.; Hao, Ke; Hoffman, Joshua D.; Hokanson, John E.; Homuth, Georg; Joshi, Peter K.; Joubert, Philippe; Langenberg, Claudia; Li, Xuan; Li, Liming; Lin, Kuang; Lind, Lars; Locantore, Nicholas; Luan, Jian'an; Mahajan, Anubha; Maranville, Joseph C.; Murray, Alison; Nickle, David C.; Packer, Richard; Parker, Margaret M.; Paynton, Megan L.; Porteous, David J.; Prokopenko, Dmitry; Qiao, Dandi; Rawal, Rajesh; Runz, Heiko; Sayers, Ian; Sin, Don D.; Smith, Blair H.; Artigas, Maria Soler; Sparrow, David; Tal-Singer, Ruth; Timmers, Paul R. H. J.; Van den Berge, Maarten; Whittaker, John C.; Woodruff, Prescott G.; Yerges-Armstrong, Laura M.; Troyanskaya, Olga G.; Raitakari, Olli T.; Kaehoenen, Mika; Polasek, Ozren; Gyllensten, Ulf; Rudan, Igor; Deary, Ian J.; Probst-Hensch, Nicole M.; Schulz, Holger; James, Alan L.; Wilson, James F.; Stubbe, Beate; Zeggini, Eleftheria; Jarvelin, Marjo-Riitta; Wareham, Nick; Silverman, Edwin K.; Hayward, Caroline; Morris, Andrew P.; Butterworth, Adam S.; Scott, Robert A.; Walters, Robin G.; Meyers, Deborah A.; Cho, Michael H.; Strachan, David P.; Hall, Ian P.; Tobin, Martin D.; Wain, Louise V. Share Save
Deep plasma proteome characterization in two independent clinical cohorts identifies clusters of biomarkers separating benign and malign tumors in women with suspicion of ovarian cancer Enroth, Stefan; Moskov, Mikaela; Hedlund, Julia Lindberg; Popova, Svetlana; Forsberg, Simn K.; Diamanti, Klev; Lycke, Maria; Ivansson, Emma; Tolf, Anna; Sundfeldt, Karin; Stalberg, Karin; Gyllensten, Ulf Share Save
High-grade serous ovarian carcinoma detected with TP53 mutation panel and SiMSen-Seq Widjaja, Amanda Olsson; Micallef, Peter; Ulfenborg, Benjamin; Lycke, Maria; Gyllensten, Ulf; Carlsson, Therese; Osterlund, Tobias; Stahlberg, Anders; Linder, Anna; Sundfeldt, Karin Share Save
Whole-genome resequencing facilitates the development of a 50K single nucleotide polymorphism genotyping array for Scots pine (Pinus sylvestris L.) and its transferability to other pine species Barcala, Maximiliano Estravis; van der Valk, Tom; Chen, Zhiqiang; Funda, Tomas; Chaudhary, Rajiv; Klingberg, Adam; Fundova, Irena; Suontama, Mari; Hallingback, Henrik; Bernhardsson, Carolina; Nystedt, Bjorn; Ingvarsson, Par K.; Sherwood, Ellen; Street, Nathaniel; Gyllensten, Ulf; Nilsson, Ove; Wu, Harry X. Share Save
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets (vol 24, pg 1540, 2023) Zhao, Jing Hua; Stacey, David; Eriksson, Niclas; Macdonald-Dunlop, Erin; Hedman, Asa K.; Kalnapenkis, Anette; Enroth, Stefan; Cozzetto, Domenico; Digby-Bell, Jonathan; Marten, Jonathan; Folkersen, Lasse; Herder, Christian; Jonsson, Lina; Bergen, Sarah E.; Gieger, Christian; Needham, Elise J.; Hudjasov, Georgi; Surendran, Praveen; Estonian Biobank Res Team, Ozren; Paul, Dirk S.; Polasek, Ozren; Thorand, Barbara; Grallert, Harald; Roden, Michael; Vosa, Urmo; Esko, Tonu; Hayward, Caroline; Johansson, Asa; Gyllensten, Ulf; Powell, Nick; Hansson, Oskar; Mattsson-Carlgren, Niklas; Joshi, Peter K.; Danesh, John; Padyukov, Leonid; Klareskog, Lars; Landen, Mikael; Wilson, James F.; Siegbahn, Agneta; Wallentin, Lars; Maelarstig, Anders; Butterworth, Adam S.; Peters, James E. Share Save
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets Zhao, Jing Hua; Stacey, David; Eriksson, Niclas; Macdonald-Dunlop, Erin; Hedman, Asa K.; Kalnapenkis, Anette; Enroth, Stefan; Cozzetto, Domenico; Digby-Bell, Jonathan; Marten, Jonathan; Folkersen, Lasse; Herder, Christian; Jonsson, Lina; Bergen, Sarah E.; Gieger, Christian; Needham, Elise J.; Surendran, Praveen; Metspalu, Andres; Milani, Lili; Magi, Reedik; Nelis, Mari; Hudjasov, Georgi; Paul, Dirk S.; Polasek, Ozren; Thorand, Barbara; Grallert, Harald; Roden, Michael; Vosa, Urmo; Esko, Tonu; Hayward, Caroline; Johansson, Asa; Gyllensten, Ulf; Powell, Nick; Hansson, Oskar; Mattsson-Carlgren, Niklas; Joshi, Peter K.; Danesh, John; Padyukov, Leonid; Klareskog, Lars; Landen, Mikael; Wilson, James F.; Siegbahn, Agneta; Wallentin, Lars; Malarstig, Anders; Butterworth, Adam S.; Peters, James E. Share Save
Next generation pan-cancer blood proteome profiling using proximity extension assay Alvez, Maria Bueno; Edfors, Fredrik; von Feilitzen, Kalle; Zwahlen, Martin; Mardinoglu, Adil; Edqvist, Per-Henrik; Sjoblom, Tobias; Lundin, Emma; Rameika, Natallia; Enblad, Gunilla; Lindman, Henrik; Hoglund, Martin; Hesselager, Goran; Stalberg, Karin; Enblad, Malin; Simonson, Oscar E.; Haggman, Michael; Axelsson, Tomas; Aberg, Mikael; Nordlund, Jessica; Zhong, Wen; Karlsson, Max; Gyllensten, Ulf; Ponten, Fredrik; Fagerberg, Linn; Uhlen, Mathias Share Save
Forensic prediction of sex, age, height, body mass index, hip-to-waist ratio, smoking status and lipid lowering drugs using epigenetic markers and plasma proteins Llobet, Monica Ortega; Johansson, Asa; Gyllensten, Ulf; Allen, Marie; Enroth, Stefan Share Save
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia Wen, Jia; Trost, Brett; Engchuan, Worrawat; Halvorsen, Matthew; Pallotto, Linda M.; Mitina, Aleksandra; Ancalade, NaEshia; Farrell, Martilias; Backstrom, Ian; Guo, Keyi; Pellecchia, Giovanna; Thiruvahindrapuram, Bhooma; Giusti-Rodriguez, Paola; Rosen, Jonathan David; Li, Yun; Won, Hyejung; Magnusson, Patrik K. E.; Gyllensten, Ulf; Bassett, Anne S.; Hultman, Christina M.; Sullivan, Patrick F.; Yuen, Ryan K. C.; Szatkiewicz, Jin P. Share Save
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Implementing precision medicine in a regionally organized healthcare system in Sweden Fioretos, Thoas; Wirta, Valtteri; Cavelier, Lucia; Berglund, Eva; Friedman, Mikaela; Akhras, Michael; Botling, Johan; Ehrencrona, Hans; Engstrand, Lars; Helenius, Gisela; Fagerqvist, Therese; Gisselsson, David; Gruvberger-Saal, Sofia; Gyllensten, Ulf; Heidenblad, Markus; Hoglund, Kina; Jacobsson, Bo; Johansson, Maria; Johansson, Asa; Soller, Maria Johansson; Landstrom, Marene; Larsson, Par; Levin, Lars-Ake; Lindstrand, Anna; Lovmar, Lovisa; Lyander, Anna; Melin, Malin; Nordgren, Ann; Nordmark, Gunnel; Molling, Paula; Palmqvist, Lars; Palmqvist, Richard; Repsilber, Dirk; Sikora, Per; Stenmark, Bianca; Soderkvist, Peter; Stranneheim, Henrik; Strid, Tobias; Wheelock, Craig E.; Wadelius, Mia; Wedell, Anna; Edsjo, Anders; Rosenquist, Richard Share Save
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention Wang, Zhe; Emmerich, Andrew; Pillon, Nicolas J.; Moore, Tim; Hemerich, Daiane; Cornelis, Marilyn C.; Mazzaferro, Eugenia; Broos, Siacia; Ahluwalia, Tarunveer S.; Bartz, Traci M.; Bentley, Amy R.; Bielak, Lawrence F.; Chong, Mike; Chu, Audrey Y.; Berry, Diane; Dorajoo, Rajkumar; Dueker, Nicole D.; Kasbohm, Elisa; Feenstra, Bjarke; Feitosa, Mary F.; Gieger, Christian; Graff, Mariaelisa; Hall, Leanne M.; Haller, Toomas; Hartwig, Fernando P.; Hillis, David A.; Huikari, Ville; Heard-Costa, Nancy; Holzapfel, Christina; Jackson, Anne U.; Johansson, Asa; Jorgensen, Anja Moltke; Kaakinen, Marika A.; Karlsson, Robert; Kerr, Kathleen F.; Kim, Boram; Koolhaas, Chantal M.; Kutalik, Zoltan; Lagou, Vasiliki; Lind, Penelope A.; Lorentzon, Mattias; Lyytikainen, Leo-Pekka; Mangino, Massimo; Metzendorf, Christoph; Monroe, Kristine R.; Pacolet, Alexander; Perusse, Louis; Pool, Rene; Richmond, Rebecca C.; Rivera, Natalia, V; Robiou-Du-Pont, Sebastien; Schraut, Katharina E.; Schulz, Christina-Alexandra; Stringham, Heather M.; Tanaka, Toshiko; Teumer, Alexander; Turman, Constance; Van der Most, Peter J.; Vanmunster, Mathias; Van Rooij, Frank J. A.; Van Vliet-Ostaptchouk, Jana V.; Zhang, Xiaoshuai; Zhao, Jing-Hua; Zhao, Wei; Balkhiyarova, Zhanna; Balslev-Harder, Marie N.; Baumeister, Sebastian E.; Beilby, John; Blangero, John; Boomsma, Dorret, I; Brage, Soren; Braund, Peter S.; Brody, Jennifer A.; Bruinenberg, Marcel; Ekelund, Ulf; Liu, Ching-Ti; Cole, John W.; Collins, Francis S.; Cupples, L. Adrienne; Esko, Tonu; Enroth, Stefan; Faul, Jessica D.; Fernandez-Rhodes, Lindsay; Fohner, Alison E.; Franco, Oscar H.; Galesloot, Tessel E.; Gordon, Scott D.; Grarup, Niels; Hartman, Catharina A.; Heiss, Gerardo; Hui, Jennie; Illig, Thomas; Jago, Russell; James, Alan; Joshi, Peter K.; Jung, Taeyeong; Kahonen, Mika; Kilpelainen, Tuomas O.; Koh, Woon-Puay; Kolcic, Ivana; Kraft, Peter P.; Kuusisto, Johanna; Launer, Lenore J.; Li, Aihua; Linneberg, Allan; Luan, Jian'An; Vidal, Pedro Marques; Medland, Sarah E.; Milaneschi, Yuri; Moscati, Arden; Musk, Bill; Nelson, Christopher P.; Nolte, Ilja M.; Pedersen, Nancy L.; Peters, Annette; Peyser, Patricia A.; Power, Christine; Raitakari, Olli T.; Reedik, Magi; Reiner, Alex P.; Ridker, Paul M.; Rudan, Igor; Ryan, Kathy; Sarzynski, Mark A.; Scott, Laura J.; Scott, Robert A.; Sidney, Stephen; Siggeirsdottir, Kristin; Smith, Albert, V; Smith, Jennifer A.; Sonestedt, Emily; Strom, Marin; Tai, E. Shyong; Teo, Koon K.; Thorand, Barbara; Toenjes, Anke; Tremblay, Angelo; Uitterlinden, Andre G.; Vangipurapu, Jagadish; Van Schoor, Natasja; Volker, Uwe; Willemsen, Gonneke; Williams, Kayleen; Wong, Quenna; Xu, Huichun; Young, Kristin L.; Yuan, Jian Min; Zillikens, M. Carola; Zonderman, Alan B.; Ameur, Adam; Bandinelli, Stefania; Bis, Joshua C.; Boehnke, Michael; Bouchard, Claude; Chasman, Daniel, I; Smith, George Davey; De Geus, Eco J. C.; Deldicque, Louise; Dorr, Marcus; Evans, Michele K.; Ferrucci, Luigi; Fornage, Myriam; Fox, Caroline; Garland, Theodore, Jr.; Gudnason, Vilmundur; Gyllensten, Ulf; Hansen, Torben; Hayward, Caroline; Horta, Bernardo L.; Hypponen, Elina; Jarvelin, Marjo-Riitta; Johnson, W. Craig; Kardia, Sharon L. R.; Kiemeney, Lambertus A.; Laakso, Markku; Langenberg, Claudia; Lehtimaki, Terho; Le Marchand, Loic; Magnusson, Patrik K. E.; Martin, Nicholas G.; Melbye, Mads; Metspalu, Andres; Meyre, David; North, Kari E.; Ohlsson, Claes; Oldehinkel, Albertine J.; Orho-Melander, Marju; Pare, Guillaume; Park, Taesung; Pedersen, Oluf; Penninx, Brenda W. J. H.; Pers, Tune H.; Polasek, Ozren; Prokopenko, Inga; Rotimi, Charles N.; Samani, Nilesh J.; Sim, Xueling; Snieder, Harold; Sorensen, Thorkild I. A.; Spector, Tim D.; Timpson, Nicholas J.; Van Dam, Rob M.; Van der Velde, Nathalie; Van Duijn, Cornelia M.; Vollenweider, Peter; Volzke, Henry; Voortman, Trudy; Waeber, Gerard; Wareham, Nicholas J.; Weir, David R.; Wichmann, Heinz-Erich; Wilson, James F.; Hevener, Andrea L.; Krook, Anna; Zierath, Juleen R.; Thomis, Martine A., I; Loos, Ruth J. F.; Den Hoed, Marcel Share Save
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Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas Weishaupt, Holger; Cancer, Matko; Rosen, Gabriela; Holmberg, Karl O.; Haggqvist, Susana; Bunikis, Ignas; Jiang, Yiwen; Sreedharan, Smitha; Gyllensten, Ulf; Becher, Oren J.; Uhrbom, Lene; Ameur, Adam; Swartling, Fredrik J. Share Save
Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability Kierczak, Marcin; Rafati, Nima; Hoglund, Julia; Gourle, Hadrien; Lo Faro, Valeria; Schmitz, Daniel; Ek, Weronica E.; Gyllensten, Ulf; Enroth, Stefan; Ekman, Diana; Nystedt, Bjorn; Karlsson, Torgny; Johansson, Asa Share Save
CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations Hoijer, Ida; Emmanouilidou, Anastasia; Ostlund, Rebecka; van Schendel, Robin; Bozorgpana, Selma; Tijsterman, Marcel; Feuk, Lars; Gyllensten, Ulf; den Hoed, Marcel; Ameur, Adam Share Save
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