João Pedro Ferrari‐Souza - Publications, H-index & Citations

Back

João Pedro Ferrari‐Souza

Universidade Federal do Rio Grande do Sul

18H-index

156Paper Count

1.6KCitation Count

Published Papers 33

Publication Date

Spatiotemporal dynamics of tau extent and load increase in Alzheimer’s disease across four longitudinal cohorts

Nature Aging

IF19.4

2026-07-14

OAAI

Arthur C. Macedo; Lydia Trudel; Joseph Therriault; Nesrine Rahmouni; Étienne Aumont; Gleb Bezgin; Seyyed Ali Hosseini; Cécile Tissot; Tevy Chan; Stijn Servaes; Brandon Hall; Yi-Ting Wang; Kely Quispialaya-Socualaya; Marcel S. Woo; Jaime Fernandez-Arias; Jenna Stevenson; Yansheng Zheng; Marina Pereira Gonçalves; Firoza Z. Lussier; João Pedro Ferrari-Souza; Pamela C. L. Ferreira; Bruna Bellaver; Guilherme Povala; Livia Silva do Amaral; Gassan Massarweh; Jean-Paul Soucy; Karin L. Meeker; Meredith N. Braskie; Tobey J. Betthauser; Bradley T. Christian; Ramiro Eduardo Rea Reyes; Jessica K. Caldwell; Nicholas J. Ashton; Thomas K. Karikari; Henrik Zetterberg; Kaj Blennow; Eduardo R. Zimmer; Andréa L. Benedet; Sterling C. Johnson; Tharick A. Pascoal; Pedro Rosa-Neto

Save

In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer’s disease continuum

Molecular Psychiatry

IF10.1

2025-12-14

PREAI

Douglas Teixeira Leffa; Guilherme Povala; Pamela C. L. Ferreira; João Pedro Ferrari-Souza; Guilherme Bauer-Negrini; Matheus Scarpatto Rodrigues; Livia Amaral; Firoza Z. Lussier; Marina Scop Medeiros; Carolina Soares; Cristiano Schaffer Aguzzoli; Arthur C. Macedo; Joseph Therriault; Pedro Rosa-Neto; Dana L. Tudorascu; Eduardo R. Zimmer; Bruna Bellaver; Tharick A. Pascoal

Save

APOE ε4 potentiates tau related reactive astrogliosis assessed by cerebrospinal fluid YKL40 in Alzheimer’s disease

Communications Medicine

IF6.3

2025-11-20

OAAI

Lydia Trudel; Joseph Therriault; Arthur C. Macedo; Marcel S. Woo; Nesrine Rahmouni; Étienne Aumont; Stijn Servaes; Seyyed Ali Hosseini; João Pedro Ferrari-Souza; Bruna Bellaver; Pamela L. Ferreira; Tevy Chan; Yi-Ting Wang; Jaime Fernandez-Arias; Yansheng Zheng; Brandon Hall; Jenna Stevenson; Robert Hopewell; Chris Hung-Hsin Hsiao; Maxime Montembeault; Jesse Klostranec; Yasser Iturria-Medina; Paolo Vitali; Thomas K. Karikari; Andrea L. Benedet; Nicholas J. Ashton; Eduardo Zimmer; Serge Gauthier; Tharick A. Pascoal; Henrik Zetterberg; Kaj Blennow; Pedro Rosa-Neto

Save

Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer’s disease

Nature Neuroscience

IF20

2025-11-06

OAAI

João Pedro Ferrari-Souza; Guilherme Povala; Nesrine Rahmouni; Bruna Bellaver; Pamela C. L. Ferreira; Marco Antônio De Bastiani; Douglas T. Leffa; Firoza Z. Lussier; Cristiano S. Aguzzoli; Wagner S. Brum; Giovanna Carello-Collar; Wyllians V. Borelli; Joseph Therriault; Arthur C. Macedo; Stijn Servaes; Jenna Stevenson; Ilaria Pola; Serge Gauthier; Diogo O. Souza; Lucas Porcello Schilling; Mychael V. Lourenco; Gallen Triana-Baltzer; Hartmuth C. Kolb; Andréa L. Benedet; Nicholas J. Ashton; Dana L. Tudorascu; Henrik Zetterberg; Kaj Blennow; Sterling C. Johnson; Tharick A. Pascoal; Pedro Rosa-Neto; Eduardo R. Zimmer

Save

Stratifying dementia risk factors: A prediction model and hypothesis-driven analysis

Alzheimer's & Dementia

IF11.1

2025-10-28

OAAI

Daniel Arnold; Rodrigo C Barros; João Pedro Ferrari-Souza; Marco Antonio de Bastiani; Eduardo R Zimmer; Wyllians Vendramini Borelli

Save

Amyloid beta and tau are associated with the dual effect of neuroinflammation on neurodegeneration

ALZHEIMERS & DEMENTIA

IF11.1

2025-09-29

OAAI

Povala, Guilherme; Bellaver, Bruna; Bastiani, Marco Antonio De; Ferrari-Souza, Joao Pedro; Aguzzoli, Cristiano S.; Leffa, Douglas T.; Ferreira, Pamela C. L.; Lussier, Firoza Z.; Rocha, Andreia; Zalzale, Hussein; Soares, Carolina; Bauer-Negrini, Guilherme; Therriault, Joseph; Rahmouni, Nesrine; Stevenson, Jenna; Servaes, Stijn; Tissot, Cecile; Zatt, Bruno; Karikari, Thomas K.; Ikonomovic, Milos D.; Villemagne, Victor L.; Gauthier, Serge; Zimmer, Eduardo R.; Tudorascu, Dana L.; Benedet, Andrea L.; Rosa-Neto, Pedro; Pascoal, Tharick A.

Save

Reversible tau hyperphosphorylation in hibernation: a blood biomarker and brain tissue study

Acta Neuropathologica

IF9.3

2025-09-29

OAAI

Wagner S. Brum; Laia Montoliu-Gaya; Gunnar Brinkmalm; Diana Piotrowska; Elena Camporesi; Carsten Jäger; Helena S. Isaksson; Sven Martin; Jonas Kindberg; Juan Lantero-Rodriguez; João Pedro Ferrari-Souza; Alexis Moscoso; Andrea L. Benedet; Shorena Janelidze; Johan Gobom; Henrik Zetterberg; Oskar Hansson; Eduardo R. Zimmer; Nicholas J. Ashton; Thomas Arendt; Tammaryn Lashley; Jens T. Stieler; Max Holzer; Ole Fröbert; Kaj Blennow

Save

Diagnostic performance of Alzheimer’s disease blood and CSF biomarkers in a Brazilian cohort with low educational attainment

Molecular Psychiatry

IF10.1

2025-09-08

PREAI

Wyllians Vendramini Borelli; Pamela C. L. Ferreira; Wagner S. Brum; João Pedro Ferrari-Souza; Giovanna Carello-Collar; Maila Holz; Victoria Tizeli; Matheus Zschornack Strelow; Carolina Formoso; Marcia Lorena Fagundes Chaves; Andreia Rocha; Cristiano Schaffer Aguzzoli; Francieli Rohden; Débora G. Souza; Artur Francisco Schumacher Schuh; Guilherme Povala; Bruna Bellaver; Pedro Rosa-Neto; Raphael Machado Castilhos; Tharick A. Pascoal; Eduardo R. Zimmer

Save

CSF total tau as a proxy of synaptic degeneration

Nature Communications

IF15.7

2025-08-29

OAAI

Carolina Soares; Bruna Bellaver; Pamela C. L. Ferreira; Guilherme Povala; Cristiano Schaffer Aguzzoli; João Pedro Ferrari-Souza; Hussein Zalzale; Firoza Z. Lussier; Francieli Rohden; Sarah Abbas; Guilherme Bauer-Negrini; Douglas Teixeira Leffa; Andréa Lessa Benedet; Rebecca Langhough; Tobey J. Betthauser; Bradley T. Christian; Rachael E. Wilson; Dana L. Tudorascu; Pedro Rosa-Neto; Thomas K. Karikari; Henrik Zetterberg; Kaj Blennow; Eduardo R. Zimmer; Sterling C. Johnson; Tharick A. Pascoal

Save

Impact of the polygenic risk scores for attention-deficit/hyperactivity disorder in Alzheimer's disease

ALZHEIMERS & DEMENTIA

IF11.1

2025-02-25

OAAI

Leffa, DT; Povala, G; Bellaver, B; Ferrari-Souza, JP; Ferreira, PCL; Lussier, FZ; Aguzzoli, CS; Soares, C; Zalzale, H; Rohden, F; Bauer-Negrini, G; Abbas, S; Schneider, M; Therriault, J; Lopez, OL; Villemagne, VL; Klunk, WE; Tudorascu, DL; Cohen, AD; Rosa-Neto, P; Zimmer, ER; Karikari, TK; Rohde, LA; Molina, BSG; Pascoal, TA

Save

Modeling the progression of neuropsychiatric symptoms in Alzheimer's disease with PET-based Braak staging

NEUROBIOLOGY OF AGING

IF3.5

2024-12-01

OAAI

Macedo, Arthur C.; Therriault, Joseph; Tissot, Cecile; Aumont, Etienne; Servaes, Stijn; Rahmouni, Nesrine; Fernandez-Arias, Jaime; Lussier, Firoza Z.; Wang, Yi-Ting; Ng, Kok Pin; Vermeiren, Marie; Bezgin, Gleb; Socualaya, Kely Quispialaya; Stevenson, Jenna; Hosseini, Seyyed Ali; Chamoun, Mira; Ferrari-Souza, Joao Pedro; Ferreira, Pamela C. L.; Bellaver, Bruna; Leffa, Douglas Teixeira; Vitali, Paolo; Zimmer, Eduardo R.; Ismail, Zahinoor; Pascoal, Tharick A.; Gauthier, Serge; Rosa-Neto, Pedro

Save

Influence of Different Diagnostic Criteria on Alzheimer Disease Clinical Research

NEUROLOGY

IF8.5

2024-09-10

PREAI

Bieger, Andrei; Brum, Wagner S.; Borelli, Wyllians V.; Therriault, Joseph; De Bastiani, Marco A.; Moreira, Amanda G.; Benedet, Andrea L.; Ferrari-Souza, Joao Pedro; Da Costa, Jaderson C.; Souza, Diogo O.; Castilhos, Raphael M.; Schumacher Schuh, Artur Francisco; Fagundes Chaves, Marcia L.; Schoell, Michael; Zetterberg, Henrik; Blennow, Kaj; Pascoal, Tharick A.; Gauthier, Serge; Rosa-Neto, Pedro; Schilling, Lucas P.; Zimmer, Eduardo R.

Save

Omics-derived biological modules reflect metabolic brain changes in Alzheimer's disease

ALZHEIMERS & DEMENTIA

IF11.1

2024-08-14

OAAI

Povala, Guilherme; De Bastiani, Marco Antonio; Bellaver, Bruna; Ferreira, Pamela C. L.; Ferrari-Souza, Joao Pedro; Lussier, Firoza Z.; Souza, Diogo O.; Rosa-Neto, Pedro; Pascoal, Tharick A.; Zatt, Bruno; Zimmer, Eduardo R.

Save

Vascular risk burden is a key player in the early progression of Alzheimer's disease

NEUROBIOLOGY OF AGING

IF3.5

2024-04-01

OAAI

Ferrari-Souza, Joao Pedro; Brum, Wagner S.; Hauschild, Lucas A.; Da Ros, Lucas U.; Ferreira, Pamela C. L.; Bellaver, Bruna; Leffa, Douglas T.; Bieger, Andrei; Tissot, Cecile; Lussier, Firoza Z.; De Bastiani, Marco Antonio; Povala, Guilherme; Benedet, Andrea L.; Therriault, Joseph; Wang, Yi-Ting; Ashton, Nicholas J.; Zetterberg, Henrik; Blennow, Kaj; Martins, Sheila O.; Souza, Diogo O.; Rosa-Neto, Pedro; Karikari, Thomas K.; Pascoal, Tharick A.; Zimmer, Eduardo R.

Save

Predicting functional decline in aging and Alzheimer's disease with PET-based Braak staging

BRAIN COMMUNICATIONS

IF4.5

2024-02-26

OAAI

Macedo, Arthur C.; Therriault, Joseph; Tissot, Cecile; Fernandez-Arias, Jaime; Ferreira, Pamela C. L.; Vitali, Paolo; Servaes, Stijn; Rahmouni, Nesrine; Vermeiren, Marie; Bezgin, Gleb; Lussier, Firoza Z.; Stevenson, Jenna; Wang, Yi-Ting; Socualaya, Kely Quispialaya; Kunach, Peter; Nazneen, Tahnia; Hosseini, Seyyed Ali; Pallen, Vanessa; Stevenson, Alyssa; Ferrari-Souza, Joao Pedro; Bellaver, Bruna; Leffa, Douglas Teixeira; Ng, Kok Pin; Zimmer, Eduardo R.; Pascoal, Tharick A.; Gauthier, Serge; Rosa-Neto, Pedro

Save

The glutamatergic system in Alzheimer's disease: a systematic review with meta-analysis

MOLECULAR PSYCHIATRY

IF10.1

2024-02-16

PREAI

Soares, Carolina; Da Ros, Lucas Uglione; Machado, Luiza Santos; Rocha, Andreia; Lazzarotto, Gabriela; Carello-Collar, Giovanna; De Bastiani, Marco A.; Ferrari-Souza, Joao Pedro; Lussier, Firoza Z.; Souza, Diogo O.; Rosa-Neto, Pedro; Pascoal, Tharick A.; Bellaver, Bruna; Zimmer, Eduardo R.

Save

Neuropsychiatric Symptoms and Microglial Activation in Patients with Alzheimer Disease

JAMA NETWORK OPEN

IF9.7

2023-11-27

OAAI

Schaffer Aguzzoli, Cristiano; Ferreira, Pamela C. L.; Povala, Guilherme; Ferrari-Souza, Joao Pedro; Bellaver, Bruna; Soares Katz, Carolina; Zalzale, Hussein; Lussier, Firoza Z.; Rohden, Francieli; Abbas, Sarah; Leffa, Douglas T.; Scop Medeiros, Marina; Therriault, Joseph; Benedet, Andrea L.; Tissot, Cecile; Servaes, Stijn; Rahmouni, Nesrine; Cassa Macedo, Arthur; Bezgin, Gleb; Kang, Min Su; Stevenson, Jenna; Pallen, Vanessa; Cohen, Ann; Lopez, Oscar L.; Tudorascu, Dana L.; Klunk, William E.; Villemagne, Victor L.; Soucy, Jean Paul; Zimmer, Eduardo R.; Schilling, Lucas P.; Karikari, Thomas K.; Ashton, Nicholas J.; Zetterberg, Henrik; Blennow, Kaj; Gauthier, Serge; Valcour, Victor; Miller, Bruce L.; Rosa-Neto, Pedro; Pascoal, Tharick A.

Save

14-3-3 ζ/δ-reported early synaptic injury in Alzheimer's disease is independently mediated by sTREM2

JOURNAL OF NEUROINFLAMMATION

IF10.1

2023-11-24

OAAI

Woo, Marcel S.; Nilsson, Johanna; Therriault, Joseph; Rahmouni, Nesrine; Brinkmalm, Ann; Benedet, Andrea L.; Ashton, Nicholas J.; Macedo, Arthur C.; Servaes, Stijn; Wang, Yi-Ting; Tissot, Cecile; Arias, Jaime Fernandez; Hosseini, Seyyed Ali; Chamoun, Mira; Lussier, Firoza Z.; Karikari, Thomas K.; Stevenson, Jenna; Mayer, Christina; Ferrari-Souza, Joao Pedro; Kobayashi, Eliane; Massarweh, Gassan; Friese, Manuel A.; Pascoal, Tharick A.; Gauthier, Serge; Zetterberg, Henrik; Blennow, Kaj; Rosa-Neto, Pedro

Save

APOEε4 potentiates amyloid β effects on longitudinal tau pathology

NATURE AGING

IF19.4

2023-09-25

OAAI

Ferrari-Souza, Joao Pedro; Bellaver, Bruna; Ferreira, Pamela C. L.; Benedet, Andrea L.; Povala, Guilherme; Lussier, Firoza Z.; Leffa, Douglas T.; Therriault, Joseph; Tissot, Cecile; Soares, Carolina; Wang, Yi-Ting; Chamoun, Mira; Servaes, Stijn; Macedo, Arthur C.; Vermeiren, Marie; Bezgin, Gleb; Kang, Min Su; Stevenson, Jenna; Rahmouni, Nesrine; Pallen, Vanessa; Poltronetti, Nina Margherita; Cohen, Ann; Lopez, Oscar L.; Klunk, William E.; Soucy, Jean-Paul; Gauthier, Serge; Souza, Diogo O.; Triana-Baltzer, Gallen; Saad, Ziad S.; Kolb, Hartmuth C.; Karikari, Thomas K.; Villemagne, Victor L.; Tudorascu, Dana L.; Ashton, Nicholas J.; Zetterberg, Henrik; Blennow, Kaj; Zimmer, Eduardo R.; Rosa-Neto, Pedro; Pascoal, Tharick A.

Save

Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals

ALZHEIMERS & DEMENTIA

IF11.1

2023-08-03

PREAI

Ferreira, Pamela C. L.; Therriault, Joseph; Tissot, Cecile; Ferrari-Souza, Joao Pedro; Benedet, Andrea L.; Povala, Guilherme; Bellaver, Bruna; Leffa, Douglas T.; Brum, Wagner S.; Lussier, Firoza Z.; Bezgin, Gleb; Servaes, Stijn; Vermeiren, Marie; Macedo, Arthur C.; Cabrera, Arlec; Stevenson, Jenna; Triana-Baltzer, Gallen; Kolb, Hartmuth; Rahmouni, Nesrine; Klunk, William E.; Lopez, Oscar L.; Villemagne, Victor L.; Cohen, Ann; Tudorascu, Dana L.; Zimmer, Eduardo R.; Karikari, Thomas K.; Ashton, Nicholas J.; Zetterberg, Henrik; Blennow, Kaj; Gauthier, Serge; Rosa-Neto, Pedro; Pascoal, Tharick A.

Save

Research Directions