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Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor Williams, Thomas L.; Verdon, Gregory; Kuc, Rhoda E.; Currinn, Heather; Bender, Brian; Solcan, Nicolae; Schlenker, Oliver; Macrae, Robyn G. C.; Brown, Jason; Schuetz, Marco; Zhukov, Andrei; Sinha, Sanjay; de Graaf, Chris; Graef, Stefan; Maguire, Janet J.; Brown, Alastair J. H.; Davenport, Anthony P. Share Save
Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension Hong, Jason; Medzikovic, Lejla; Sun, Wasila; Wong, Brenda; Ruffenach, Gregoire; Rhodes, Christopher J.; Brownstein, Adam; Liang, Lloyd L.; Aryan, Laila; Li, Min; Vadgama, Arjun; Kurt, Zeyneb; Schwantes-An, Tae-Hwi; Mickler, Elizabeth A.; Graf, Stefan; Eyries, Melanie; Lutz, Katie A.; Pauciulo, Michael W.; Trembath, Richard C.; Perros, Frederic; Montani, David; Morrell, Nicholas W.; Soubrier, Florent; Wilkins, Martin R.; Nichols, William C.; Aldred, Micheala A.; Desai, Ankit A.; Tregouet, David-Alexandre; Umar, Soban; Saggar, Rajan; Channick, Richard; Tuder, Rubin M.; Geraci, Mark W.; Stearman, Robert S.; Yang, Xia; Eghbali, Mansoureh Share Save
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Reversal of pulmonary veno-occlusive disease phenotypes by inhibition of the integrated stress response Prabhakar, Amit; Kumar, Rahul; Wadhwa, Meetu; Ghatpande, Prajakta; Zhang, Jingkun; Zhao, Ziwen; Lizama, Carlos O.; Kharbikar, Bhushan N.; Graef, Stefan; Treacy, Carmen M.; Morrell, Nicholas W.; Graham, Brian B.; Lagna, Giorgio; Hata, Akiko Share Save
Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism Liley, James; Newnham, Michael; Bleda, Marta; Bunclark, Katherine; Auger, William; Barbera, Joan Albert; Bogaard, Harm; Delcroix, Marion; Fernandes, Timothy M.; Howard, Luke; Jenkins, David; Lang, Irene; Mayer, Eckhard; Rhodes, Chris; Simpson, Michael; Southgate, Laura; Trembath, Richard; Wharton, John; Wilkins, Martin R.; Graf, Stefan; Morrell, Nicholas; Zaba, Joanna Pepke; Toshner, Mark Share Save
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Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension Alhathli, Elham; Julian, Thomas; Ul Abideen Girach, Zain; Thompson, A. A. Roger; Rhodes, Christopher; Graf, Stefan; Errington, Niamh; Wilkins, Martin R.; Lawrie, Allan; Wang, Dennis; Cooper-Knock, Johnathan Share Save
Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension Tai, Yi-Yin; Yu, Qiujun; Tang, Ying; Sun, Wei; Kelly, Neil J.; Okawa, Satoshi; Zhao, Jingsi; Schwantes-An, Tae-Hwi; Lacoux, Caroline; Torrino, Stephanie; Al Aaraj, Yassmin; El Khoury, Wadih; Negi, Vinny; Liu, Mingjun; Corey, Catherine G.; Belmonte, Frances; Vargas, Sara O.; Schwartz, Brian; Bhat, Bal; Chau, B. Nelson; Karnes, Jason H.; Satoh, Taijyu; Barndt, Robert J.; Wu, Haodi; Parikh, Victoria N.; Wang, Jianrong; Zhang, Yingze; Mcnamara, Dennis; Li, Gang; Speyer, Gil; Wang, Bing; Shiva, Sruti; Kaufman, Brett; Kim, Seungchan; Gomez, Delphine; Mari, Bernard; Cho, Michael H.; Boueiz, Adel; Pauciulo, Michael W.; Southgate, Laura; Trembath, Richard C.; Sitbon, Olivier; Humbert, Marc; Graf, Stefan; Morrell, Nicholas W.; Rhodes, Christopher J.; Wilkins, Martin R.; Nouraie, Mehdi; Nichols, William C.; Desai, Ankit A.; Bertero, Thomas; Chan, Stephen Y. Share Save
Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension Ulrich, Anna; Wu, Yukyee; Draisma, Harmen; Wharton, John; Swietlik, Emilia M.; Cebola, Ines; Vasilaki, Eleni; Balkhiyarova, Zhanna; Jarvelin, Marjo-Riitta; Auvinen, Juha; Herzig, Karl-Heinz; Coghlan, J. Gerry; Lordan, James; Church, Colin; Howard, Luke S.; Pepke-Zaba, Joanna; Toshner, Mark; Wort, Stephen J.; Kiely, David G.; Condliffe, Robin; Lawrie, Allan; Graf, Stefan; Morrell, Nicholas W.; Wilkins, Martin R.; Prokopenko, Inga; Rhodes, Christopher J. Share Save
SURVIVAL OF IPAH PATIENTS WITH AND WITHOUT COMORBIDITY Reddy, Sa; Polwarth, Gj; Graf, S.; Morrell, Nw; De Bie, Emd; Bunclark, K.; Cannon, J.; Sheares, Kk; Taboada, D.; Toshner, Mr; Pepke-Zaba, J. Share Save
Defining the clinical validity of genes reported to cause pulmonary arterial hypertension Welch, Carrie L.; Aldred, Micheala A.; Balachandar, Srimmitha; Dooijes, Dennis; Eichstaedt, Christina A.; Graef, Stefan; Houweling, Arjan C.; Machado, Rajiv D.; Pandya, Divya; Prapa, Matina; Shaukat, Memoona; Southgate, Laura; Tenorio-Castano, Jair; Chung, Wendy K. Share Save
Molecular Function and Contribution of TBX4 in Development and Disease Karolak, Justyna A.; Welch, Carrie L.; Mosimann, Christian; Bzdega, Katarzyna; West, James D.; Montani, David; Eyries, Melanie; Mullen, Mary P.; Abman, Steven H.; Prapa, Matina; Graf, Stefan; Morrell, Nicholas W.; Hemnes, Anna R.; Perros, Frederic; Hamid, Rizwan; Logan, Malcolm P. O.; Whitsett, Jeffrey; Galambos, Csaba; Stankiewicz, Pawel; Chung, Wendy K.; Austin, Eric D. Share Save
First Genotype-Phenotype Study in TBX4 Syndrome Gain-of-Function Mutations Causative for Lung Disease Prapa, Matina; Lago-Docampo, Mauro; Swietlik, Emilia M.; Montani, David; Eyries, Melanie; Humbert, Marc; Welch, Carrie L.; Chung, Wendy K.; Berger, Rolf M. F.; Bogaard, Harm Jan; Danhaive, Olivier; Escribano-Subias, Pilar; Gall, Henning; Girerd, Barbara; Hernandez-Gonzalez, Ignacio; Holden, Simon; Hunt, David; Jansen, Samara M. A.; Kerstjens-Frederikse, Wilhelmina; Kiely, David G.; Lapunzina, Pablo; McDermott, John; Moledina, Shahin; Pepke-Zaba, Joanna; Polwarth, Gary J.; Schotte, Gwen; Tenorio-Castano, Jair; Thompson, A. A. Roger; Wharton, John; Wort, Stephen J.; Megy, Karyn; Mapeta, Rutendo; Treacy, Carmen M.; Martin, Jennifer M.; Li, Wei; Swift, Andrew J.; Upton, Paul D.; Morrell, Nicholas W.; Graf, Stefan; Valverde, Diana Share Save
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Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood Kariotis, Sokratis; Jammeh, Emmanuel; Swietlik, Emilia M.; Pickworth, Josephine A.; Rhodes, Christopher J.; Otero, Pablo; Wharton, John; Iremonger, James; Dunning, Mark J.; Pandya, Divya; Mascarenhas, Thomas S.; Errington, Niamh; Thompson, A. A. Roger; Romanoski, Casey E.; Rischard, Franz; Garcia, Joe G. N.; Yuan, Jason X. -J.; An, Tae-Hwi Schwantes; Desai, Ankit A.; Coghlan, Gerry; Lordan, Jim; Corris, Paul A.; Howard, Luke S.; Condliffe, Robin; Kiely, David G.; Church, Colin; Pepke-Zaba, Joanna; Toshner, Mark; Wort, Stephen; Graf, Stefan; Morrell, Nicholas W.; Wilkins, Martin R.; Lawrie, Allan; Wang, Dennis Share Save
Genetic counselling and testing in pulmonary arterial hypertension: a consensus statement on behalf of the International Consortium for Genetic Studies in PAH Eichstaedt, Christina A.; Belge, Catharina; Chung, Wendy K.; Graef, Stefan; Gruenig, Ekkehard; Montani, David; Quarck, Rozenn; Tenorio-Castano, Jair A.; Soubrier, Florent; Trembath, Richard C.; Morrell, Nicholas W. Share Save
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