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Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension Hong, Jason; Medzikovic, Lejla; Sun, Wasila; Wong, Brenda; Ruffenach, Gregoire; Rhodes, Christopher J.; Brownstein, Adam; Liang, Lloyd L.; Aryan, Laila; Li, Min; Vadgama, Arjun; Kurt, Zeyneb; Schwantes-An, Tae-Hwi; Mickler, Elizabeth A.; Graf, Stefan; Eyries, Melanie; Lutz, Katie A.; Pauciulo, Michael W.; Trembath, Richard C.; Perros, Frederic; Montani, David; Morrell, Nicholas W.; Soubrier, Florent; Wilkins, Martin R.; Nichols, William C.; Aldred, Micheala A.; Desai, Ankit A.; Tregouet, David-Alexandre; Umar, Soban; Saggar, Rajan; Channick, Richard; Tuder, Rubin M.; Geraci, Mark W.; Stearman, Robert S.; Yang, Xia; Eghbali, Mansoureh Share Save
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Fluorinated perhexiline derivative attenuates vascular proliferation in pulmonary arterial hypertension smooth muscle cells Griffiths, Kayleigh; Grand, Roger J.; Horan, Ian; Certo, Michelangelo; Keeler, Ross C.; Mauro, Claudio; Tseng, Chih-Chung; Greig, Iain; Morrell, Nicholas W.; Zanda, Matteo; Frenneaux, Michael P.; Madhani, Melanie Share Save
Reversal of pulmonary veno-occlusive disease phenotypes by inhibition of the integrated stress response Prabhakar, Amit; Kumar, Rahul; Wadhwa, Meetu; Ghatpande, Prajakta; Zhang, Jingkun; Zhao, Ziwen; Lizama, Carlos O.; Kharbikar, Bhushan N.; Graef, Stefan; Treacy, Carmen M.; Morrell, Nicholas W.; Graham, Brian B.; Lagna, Giorgio; Hata, Akiko Share Save
Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism Liley, James; Newnham, Michael; Bleda, Marta; Bunclark, Katherine; Auger, William; Barbera, Joan Albert; Bogaard, Harm; Delcroix, Marion; Fernandes, Timothy M.; Howard, Luke; Jenkins, David; Lang, Irene; Mayer, Eckhard; Rhodes, Chris; Simpson, Michael; Southgate, Laura; Trembath, Richard; Wharton, John; Wilkins, Martin R.; Graf, Stefan; Morrell, Nicholas; Zaba, Joanna Pepke; Toshner, Mark Share Save
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Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension Tai, Yi-Yin; Yu, Qiujun; Tang, Ying; Sun, Wei; Kelly, Neil J.; Okawa, Satoshi; Zhao, Jingsi; Schwantes-An, Tae-Hwi; Lacoux, Caroline; Torrino, Stephanie; Al Aaraj, Yassmin; El Khoury, Wadih; Negi, Vinny; Liu, Mingjun; Corey, Catherine G.; Belmonte, Frances; Vargas, Sara O.; Schwartz, Brian; Bhat, Bal; Chau, B. Nelson; Karnes, Jason H.; Satoh, Taijyu; Barndt, Robert J.; Wu, Haodi; Parikh, Victoria N.; Wang, Jianrong; Zhang, Yingze; Mcnamara, Dennis; Li, Gang; Speyer, Gil; Wang, Bing; Shiva, Sruti; Kaufman, Brett; Kim, Seungchan; Gomez, Delphine; Mari, Bernard; Cho, Michael H.; Boueiz, Adel; Pauciulo, Michael W.; Southgate, Laura; Trembath, Richard C.; Sitbon, Olivier; Humbert, Marc; Graf, Stefan; Morrell, Nicholas W.; Rhodes, Christopher J.; Wilkins, Martin R.; Nouraie, Mehdi; Nichols, William C.; Desai, Ankit A.; Bertero, Thomas; Chan, Stephen Y. Share Save
Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension Ulrich, Anna; Wu, Yukyee; Draisma, Harmen; Wharton, John; Swietlik, Emilia M.; Cebola, Ines; Vasilaki, Eleni; Balkhiyarova, Zhanna; Jarvelin, Marjo-Riitta; Auvinen, Juha; Herzig, Karl-Heinz; Coghlan, J. Gerry; Lordan, James; Church, Colin; Howard, Luke S.; Pepke-Zaba, Joanna; Toshner, Mark; Wort, Stephen J.; Kiely, David G.; Condliffe, Robin; Lawrie, Allan; Graf, Stefan; Morrell, Nicholas W.; Wilkins, Martin R.; Prokopenko, Inga; Rhodes, Christopher J. Share Save
Allosteric Inhibition Restricts Motion of the SMURF1 Glycine Hinge and Reverses Experimental Pulmonary Arterial Hypertension Rothman, Alex M.; Florentin, Amir; Quigley, Catherine; Zink, Florence; Bonneau, Olivier; Hemming, Rene; Hachey, Amanda; Rejtar, Tomas; Thaker, Maulik; Jain, Rishi; Zhang, Ji-Hu; Cotesta, Simona; Ottl, Johannes; Kordinsky, Alina; Avishid, Reut; Troxler, Thomas; Binmahfooz, Sarah K.; Morrell, Nicholas W.; Humbert, Marc; Cobb, Jennifer; Osterman, Nils; Tallerico, John Share Save
SURVIVAL OF IPAH PATIENTS WITH AND WITHOUT COMORBIDITY Reddy, Sa; Polwarth, Gj; Graf, S.; Morrell, Nw; De Bie, Emd; Bunclark, K.; Cannon, J.; Sheares, Kk; Taboada, D.; Toshner, Mr; Pepke-Zaba, J. Share Save
MUTATIONS IN GCN2 CAUSE PULMONARY VASCULAR DISEASE VIA DYSFUNCTIONAL INFLAMMATORY PATHWAYS Schweining, M.; Southwood, M.; Moore, S.; Crosby, A.; Kay, R.; Kishore, K.; Thompson, R.; Morrell, N. W.; Marciniak, S. J.; Soon, E. Share Save
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SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension Walters, Rachel; Vasilaki, Eleni; Aman, Jurjan; Chen, Chien-Nien; Wu, Yukyee; Liang, Olin D.; Ashek, Ali; Dubois, Olivier; Zhao, Lin; Sabrin, Farah; Cebola, Ines; Ferrer, Jorge; Morrell, Nicholas W.; Klinger, James R.; Wilkins, Martin R.; Zhao, Lan; Rhodes, Christopher J. Share Save
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