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Unconventional receptor functions and location-biased signaling of the lactate GPCR in the nucleus Nezhady, Mohammad Ali Mohammad; Cagnone, Gael; Bajon, Emmanuel; Chaudhari, Prabhas; Modaresinejad, Monir; Hardy, Pierre; Maggiorani, Damien; Quiniou, Christiane; Joyal, Jean-Sebastien; Beausejour, Christian; Chemtob, Sylvain Share Save
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CRISPR Screens Identify Key Regulators of NK Cell Cytotoxicity in Cancer Therapy Rethacker, Louise; Romero, Hugo; Dulong, Joshua; Sasseville, Marc; Lalonde, Marie-Eve; Gadoury, Christine; Beland, Kathie; Beausejour, Christian; Marcotte, Richard; Haddad, Elie Share Save
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Clearance of defective muscle stem cells by senolytics restores myogenesis in myotonic dystrophy type 1 Conte, Talita C. C.; Duran-Bishop, Gilberto; Orfi, Zakaria; Mokhtari, Ines; Deprez, Alyson; Cote, Isabelle; Molina, Thomas; Kim, Tae-Yeon; Tellier, Lydia; Roussel, Marie-Pier; Maggiorani, Damien; Benabdallah, Basma; Leclerc, Severine; Feulner, Lara; Pellerito, Ornella; Mathieu, Jean; Andelfinger, Gregor; Gagnon, Cynthia; Beausejour, Christian; McGraw, Serge; Duchesne, Elise; Dumont, Nicolas A. A. Share Save
Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1 Itahana, K; Zou, Y; Itahana, Y; Martinez, JL; Beausejour, C; Jacobs, JJL; van Lohuizen, M; Band, V; Campisi, J; Dimri, GP Share Save
Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers Apavaloaei, Anca; Hesnard, Leslie; Hardy, Marie-Pierre; Benabdallah, Basma; Ehx, Gregory; Theriault, Catherine; Laverdure, Jean-Philippe; Durette, Chantal; Lanoix, Joel; Courcelles, Mathieu; Noronha, Nandita; Chauhan, Kapil Dev; Lemieux, Sebastien; Beausejour, Christian; Bhatia, Mick; Thibault, Pierre; Perreault, Claude Share Save
Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions Moquin-Beaudry, Gael; Benabdallah, Basma; Maggiorani, Damien; Le, Oanh; Li, Yuanyi; Colas, Chloe; Raggi, Claudia; Ellezam, Benjamin; M'callum, Marie-Agnes; Dal Soglio, Dorothee; Guimond, Jean, V; Paganelli, Massimiliano; Haddad, Elie; Beausejour, Christian Share Save
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Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition Crespo-Garcia, Sergio; Tsuruda, Pamela R.; Dejda, Agnieszka; Ryan, Rathi D.; Fournier, Frederik; Chaney, Shawnta Y.; Pilon, Frederique; Dogan, Taner; Cagnone, Gael; Patel, Priyanka; Buscarlet, Manuel; Dasgupta, Sonali; Girouard, Gabrielle; Rao, Surabhi R.; Wilson, Ariel M.; O'Brien, Robert; Juneau, Rachel; Guber, Vera; Dubrac, Alexandre; Beausejour, Christian; Armstrong, Scott; Mallette, Frederick A.; Yohn, Christopher B.; Joyal, Jean-Sebastien; Marquess, Dan; Beltran, Pedro J.; Sapieha, Przemyslaw Share Save
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Myogenic progenitor cells derived from human induced pluripotent stem cell are immune-tolerated in humanized mice Benabdallah, Basma; Desaulniers-Langevin, Cynthia; Goyer, Marie-Lyn; Colas, Chloe; Maltais, Chantale; Li, Yuanyi; Guimond, Jean V.; Tremblay, Jacques P.; Haddad, Elie; Beausejour, Christian Share Save
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Targeting MYC overexpressing leukemia with cardiac glycoside proscillaridin through downregulation of histone acetyltransferases Da Costa, Elodie Marie; Armaos, Gregory; McInnes, Gabrielle; Beaudry, Annie; Moquin-Beaudry, Gael; Bertrand-Lehouillier, Virginie; Caron, Maxime; St-Onge, Pascal; Jonhson, Jeffrey R.; Krogan, Nevan; Sai, Yuka; Downey, Michale; Rafei, Moutih; Boileau, Meaghan; Eppert, Kolja; Florez-Diaz, Ema; Haman, Andre; Trang Hoang; Sinnett, Daniel; Beausejour, Christian; McGraw, Serge; Raynal, Noel J. Share Save
Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation Da Costa, Elodie M.; Armaos, Gregory; McInnes, Gabrielle; Beaudry, Annie; Moquin-Beaudry, Gael; Bertrand-Lehouillier, Virginie; Caron, Maxime; Richer, Chantal; St-Onge, Pascal; Johnson, Jeffrey R.; Krogan, Nevan; Sai, Yuka; Downey, Michael; Rafei, Moutih; Boileau, Meaghan; Eppert, Kolja; Flores-Diaz, Ema; Haman, Andre; Hoang, Trang; Sinnett, Daniel; Beausejour, Christian; McGraw, Serge; Raynal, Noel J. -M. Share Save
Restored immune cell functions upon clearance of senescence in the irradiated splenic environment Palacio, Lina; Goyer, Marie-Lyn; Maggiorani, Damien; Espinosa, Andrea; Villeneuve, Norbert; Bourbonnais, Sara; Moquin-Beaudry, Gael; Le, Oanh; Demaria, Marco; Davalos, Albert R.; Decaluwe, Helene; Beausejour, Christian Share Save