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Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity Krause, Christin; Britsemmer, Jan H.; Bernecker, Miriam; Molenaar, Anna; Taege, Natalie; Lopez-Alcantara, Nuria; Geissler, Cathleen; Kaehler, Meike; Iben, Katharina; Judycka, Anna; Wagner, Jonas; Wolter, Stefan; Mann, Oliver; Pfluger, Paul; Cascorbi, Ingolf; Lehnert, Hendrik; Stemmer, Kerstin; Schriever, Sonja C.; Kirchner, Henriette Share Save
A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes Glunk, Viktoria; Laber, Samantha; Sinnott-Armstrong, Nasa; Sobreira, Debora R.; Strobel, Sophie M.; Batista, Thiago M.; Kubitz, Phil; Moud, Bahareh Nemati; Ebert, Hannah; Huang, Yi; Brandl, Beate; Garbo, Garrett; Honecker, Julius; Stirling, David R.; Abdennur, Nezar; Calabuig-Navarro, Virtu; Skurk, Thomas; Ocvirk, Soeren; Stemmer, Kerstin; Cimini, Beth A.; Carpenter, Anne E.; Dankel, Simon N.; Lindgren, Cecilia M.; Hauner, Hans; Nobrega, Marcelo A.; Claussnitzer, Melina Share Save
Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo Kulaj, Konxhe; Harger, Alexandra; Bauer, Michaela; Caliskan, Oezuem S.; Gupta, Tilak Kumar; Chiang, Dapi Menglin; Milbank, Edward; Reber, Josefine; Karlas, Angelos; Kotzbeck, Petra; Sailer, David N.; Volta, Francesco; Lutter, Dominik; Prakash, Sneha; Merl-Pham, Juliane; Ntziachristos, Vasilis; Hauner, Hans; Pfaffl, Michael W.; Tschoep, Matthias H.; Mueller, Timo D.; Hauck, Stefanie M.; Engel, Benjamin D.; Gerdes, Jantje M.; Pfluger, Paul T.; Krahmer, Natalie; Stemmer, Kerstin Share Save
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice Quarta, Carmelo; Stemmer, Kerstin; Novikoff, Aaron; Yang, Bin; Klingelhuber, Felix; Harger, Alex; Bakhti, Mostafa; Bastidas-Ponce, Aimee; Bauge, Eric; Campbell, Jonathan E.; Capozzi, Megan; Clemmensen, Christoffer; Collden, Gustav; Cota, Perla; Douros, Jon; Drucker, Daniel J.; DuBois, Barent; Feuchtinger, Annette; Garcia-Caceres, Cristina; Grandl, Gerald; Hennuyer, Nathalie; Herzig, Stephan; Hofmann, Susanna M.; Knerr, Patrick J.; Kulaj, Konxhe; Lalloyer, Fanny; Lickert, Heiko; Liskiewicz, Arek; Liskiewicz, Daniela; Maity, Gandhari; Perez-Tilve, Diego; Prakash, Sneha; Sanchez-Garrido, Miguel A.; Zhang, Qian; Staels, Bart; Krahmer, Natalie; DiMarchi, Richard D.; Tschoep, Matthias H.; Finan, Brian; Mueller, Timo D. Share Save
Adipose cells and tissues soften with lipid accumulation while in diabetes adipose tissue stiffens Abuhattum, Shada; Kotzbeck, Petra; Schluessler, Raimund; Harger, Alexandra; de Schellenberger, Angela Ariza; Kim, Kyoohyun; Escolano, Joan-Carles; Mueller, Torsten; Braun, Juergen; Wabitsch, Martin; Tschoep, Matthias; Sack, Ingolf; Brankatschk, Marko; Guck, Jochen; Stemmer, Kerstin; Taubenberger, Anna, V Share Save
Gut HIF2α signaling is increased after VSG, and gut activation of HIF2α decreases weight, improves glucose, and increases GLP-1 secretion Evers, Simon S.; Shao, Yikai; Ramakrishnan, Sadeesh K.; Shin, Jae Hoon; Bozadjieva-Kramer, Nadejda; Irmler, Martin; Stemmer, Kerstin; Sandoval, Darleen A.; Shah, Yatrik M.; Seeley, Randy J. Share Save
Vertical sleeve gastrectomy triggers fast (3-cell recovery upon overt diabetes Oppenlaender, Lena; Palit, Subarna; Stemmer, Kerstin; Greisle, Tobias; Sterr, Michael; Salinno, Ciro; Bastidas-Ponce, Aimee; Feuchtinger, Annette; Boettcher, Anika; Ansarullah; Theis, Fabian J.; Lickert, Heiko Share Save
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice Aliluev, Alexandra; Tritschler, Sophie; Sterr, Michael; Oppenlaender, Lena; Hinterdobler, Julia; Greisle, Tobias; Irmler, Martin; Beckers, Johannes; Sun, Na; Walch, Axel; Stemmer, Kerstin; Kindt, Alida; Krumsiek, Jan; Tschop, Matthias H.; Luecken, Malte D.; Theis, Fabian J.; Lickert, Heiko; Boettcher, Anika Share Save
Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists Novikoff, Aaron; O'Brien, Shannon L.; Bernecker, Miriam; Grandl, Gerald; Kleinert, Maximilian; Knerr, Patrick J.; Stemmer, Kerstin; Klingenspor, Martin; Zeigerer, Anja; DiMarchi, Richard; Tschoep, Matthias H.; Finan, Brian; Calebiro, Davide; Mueller, Timo D. Share Save
Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice Sachs, Stephan; Niu, Lili; Geyer, Philipp; Jall, Sigrid; Kleinert, Maximilian; Feuchtinger, Annette; Stemmer, Kerstin; Brielmeier, Markus; Finan, Brian; DiMarchi, Richard D.; Tschop, Matthias H.; Wewer Albrechtsen, Nicolai; Mann, Matthias; Mueller, Timo D.; Hofmann, Susanna M. Share Save
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity Schriever, Sonja C.; Kabra, Dhiraj G.; Pfuhlmann, Katrin; Baumann, Peter; Baumgart, Emily, V; Nagler, Joachim; Seebacher, Fabian; Harrison, Luke; Irmler, Martin; Kullmann, Stephanie; Correa-da-Silva, Felipe; Giesert, Florian; Jain, Ruchi; Schug, Hannah; Castel, Julien; Martinez, Sarah; Wu, Moya; Haering, Hans-Ulrich; de Angelis, Martin Hrabe; Beckers, Johannes; Mueller, Timo D.; Stemmer, Kerstin; Wurst, Wolfgang; Rozman, Jan; Nogueiras, Ruben; De Angelis, Meri; Molkentin, Jeffery D.; Krahmer, Natalie; Yi, Chun-Xia; Schmidt, Mathias, V; Luquet, Serge; Heni, Martin; Tschoep, Matthias H.; Pfluger, Paul T. Share Save
Plasma Proteomic Profiling Delineates Treatment Efficacy of a GLP-1/GIP Coagonist in Female and Male Mice Hofmann, Susanna M.; Albrechtsen, Nicolai J. Wewer; Tschoep, Matthias H.; Feuchtinger, Annette; Brielmeier, Markus; Finan, Brian; Dimarchi, Richard; Kleinert, Maximilian; Sachs, Stephan; Mueller, Timo D.; Stemmer, Kerstin; Mann, Matthias Share Save
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation Fischer, Katrin; Fenzl, Anna; Liu, Dianxin; Dyar, Kenneth A.; Kleinert, Maximilian; Brielmeier, Markus; Clemmensen, Christoffer; Fedl, Anna; Finan, Brian; Gessner, Andre; Jastroch, Martin; Huang, Jianfeng; Keipert, Susanne; Klingenspor, Martin; Bruening, Jens C.; Kneilling, Manfred; Maier, Florian C.; Othman, Ahmed E.; Pichler, Bernd J.; Pramme-Steinwachs, Ines; Sachs, Stephan; Scheideler, Angelika; Thaiss, Wolfgang M.; Uhlenhaut, Henriette; Ussar, Siegfried; Woods, Stephen C.; Zorn, Julia; Stemmer, Kerstin; Collins, Sheila; Diaz-Meco, Maria; Moscat, Jorge; Tschoep, Matthias H.; Mueller, Timo D. Share Save
Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity Jall, Sigrid; De Angelis, Meri; Lundsgaard, Anne-Marie; Fritzen, Andreas M.; Nicolaisen, Trine S.; Klein, Anders B.; Novikoff, Aaron; Sachs, Stephan; Richter, Erik A.; Kiens, Bente; Schramm, Karl-Werner; Tschoep, Matthias H.; Stemmer, Kerstin; Clemmensen, Christoffer; Mueller, Timo D.; Kleinert, Maximilian Share Save
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Glucagon-like peptide 1 (GLP-1) Mueller, T. D.; Finan, B.; Bloom, S. R.; D'Alessio, D.; Drucker, D. J.; Flatt, P. R.; Fritsche, A.; Gribble, F.; Grill, H. J.; Habener, J. F.; Holst, J. J.; Langhans, W.; Meier, J. J.; Nauck, M. A.; Perez-Tilve, D.; Pocai, A.; Reimann, F.; Sandoval, D. A.; Schwartz, T. W.; Seeley, R. J.; Stemmer, K.; Tang-Christensen, M.; Woods, S. C.; DiMarchi, R. D.; Tschoep, M. H. Share Save
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity Seitz, Susanne; Kwon, Yun; Hartleben, Goetz; Juelg, Julia; Sekar, Revathi; Krahmer, Natalie; Najafi, Bahar; Loft, Anne; Gancheva, Sofiya; Stemmer, Kerstin; Feuchtinger, Annette; de Angelis, Martin Hrabe; Mueller, Timo D.; Mann, Matthias; Blueher, Matthias; Roden, Michael; Diaz, Mauricio Berriel; Behrends, Christian; Gilleron, Jerome; Herzig, Stephan; Zeigerer, Anja Share Save
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