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Duplan, Eric; Bernardin, Aurore; Goiran, Thomas; Leroudier, Nathalie; Casimiro, Mathew; Pestell, Richard; Tanaka, Shinya; Malleval, Celine; Honnorat, Jerome; Idbaih, Ahmed; Martin, Lucie; Castel, Helene; Checler, Frederic; Alves da Costa, Cristine Share Save Share Save Share Save Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17Dolla, Guillaume; Nicolas, Sarah; dos Santos, Ligia Ramos; Bourgeois, Alexandre; Pardossi-Piquard, Raphaelle; Bihl, Franck; Zaghrini, Christelle; Justino, Joana; Payre, Christine; Mansuelle, Pascal; Garbers, Christoph; Ronco, Pierre; Checler, Frederic; Lambeau, Gerard; Petit-Paitel, Agnes Share Save Mitochondrial alterations in fibroblasts from sporadic Alzheimer's disease (AD) patients correlate with AD-related clinical hallmarksEysert, Fanny; Kinoshita, Paula-Fernanda; Lagarde, Julien; Lacas-Gervais, Sandra; Xicota, Laura; Dorothee, Guillaume; Bottlaender, Michel; Checler, Frederic; Potier, Marie-Claude; Sarazin, Marie; Chami, Mounia Share Save The amyloid precursor protein and its derived fragments concomitantly contribute to the alterations of mitochondrial transport machinery in Alzheimer's diseaseVaillant-Beuchot, Loan; Eysert, Fanny; Duval, Blandine; Kinoshita, Paula Fernanda; Pardossi-Piquard, Raphaelle; Bauer, Charlotte; Eddarkaoui, Sabiha; Buee, Luc; Checler, Frederic; Chami, Mounia Share Save Share Save Correction to: Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology (vol 132, 257, 2016)Lauritzen, Inger; Pardossi-Piquard, Raphaelle; Bourgeois, Alexandre; Pagnotta, Sophie; Biferi, Maria-Grazia; Barkats, Martine; Lacor, Pascale; Klein, William; Bauer, Charlotte; Checler, Frederic Share Save The η-secretase-derived APP fragment ηCTF is localized in Golgi, endosomes and extracellular vesicles and contributes to Aβ productionAfram, Elissa; Lauritzen, Inger; Bourgeois, Alexandre; El Manaa, Wejdane; Duplan, Eric; Chami, Mounia; Valverde, Audrey; Charlotte, Bauer; Pardossi-Piquard, Raphaelle; Checler, Frederic Share Save Share Save Share Save MT5-MMP controls APP and β-CTF/C99 metabolism through proteolytic-dependent and -independent mechanisms relevant for Alzheimer's diseaseGarcia-Gonzalez, Laura; Paumier, Jean-Michel; Louis, Laurence; Pilat, Dominika; Bernard, Anne; Stephan, Delphine; Jullien, Nicolas; Checler, Frederic; Nivet, Emmanuel; Khrestchatisky, Michel; Baranger, Kevin; Rivera, Santiago Share Save Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiologyEl Manaa, Wejdane; Duplan, Eric; Goiran, Thomas; Lauritzen, Inger; Vaillant Beuchot, Loan; Lacas-Gervais, Sandra; Morais, Vanessa Alexandra; You, Han; Qi, Ling; Salazar, Mario; Ozcan, Umut; Chami, Mounia; Checler, Frederic; Alves da Costa, Cristine Share Save Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer's disease (AD) mouse model and is increased at early stage in sporadic AD brainValverde, Audrey; Dunys, Julie; Lorivel, Thomas; Debayle, Delphine; Gay, Anne-Sophie; Lacas-Gervais, Sandra; Roques, Bernard P.; Chami, Mounia; Checler, Frederic Share Save Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner (Nov, 10.1038/s41380-020-00926-w, 2020)Eysert, Fanny; Coulon, Audrey; Boscher, Emmanuelle; Vreulx, Anais-Camille; Flaig, Amandine; Mendes, Tiago; Hughes, Sandrine; Grenier-Boley, Benjamin; Hanoulle, Xavier; Demiautte, Florie; Bauer, Charlotte; Marttinen, Mikael; Takalo, Mari; Amouyel, Philippe; Desai, Shruti; Pike, Ian; Hiltunen, Mikko; Checler, Frederic; Farinelli, Melissa; Delay, Charlotte; Malmanche, Nicolas; Hebert, Sebastien S.; Dumont, Julie; Kilinc, Devrim; Lambert, Jean-Charles; Chapuis, Julien Share Save Share Save Share Save 
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