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J

John E. Dick

Princess Margaret Hospital

107H-index
833Paper Count
6.6WCitation Count
Published Papers 142
Publication Date
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FATP2-mediated lipid metabolism enhances chimeric antigen receptor T-cell therapy resistance in B-cell acute lymphoblastic leukemia
errLeukemia
IF13.4
err2026-06-30
err0
errOAAI
errClarissa Garcia; Kaylyn U. Lyons; Julian Grandvallet Contreras; Tian Liu; Alexis J. Donnelly; Amanda J. Novak; Amy Argabright; Colin Anderson; Abby Grier; Sabrina Smith; Joshua Michlin; Jesutomisin Olusoji; Railey G. Mikeska; Xin Zhou; Huimin Geng; Jeremy T. Rahkola; Hiten N. Patel; Jeffrey G. Jacot; Markus Müschen; Angelo D’Alessandro; John E. Dick; Ilaria Iacobucci; Charles G. Mullighan; Julie A. Reisz; Tzu Phang; M. Eric Kohler; Matthew T. Witkowski
errShare
errSave
Human haematopoietic stem cells remember inflammatory stress
errNature
IF48.5
err2026-05-27
err0
errOAAI
errAndy G. X. Zeng; Murtaza S. Nagree; Niels Asger Jakobsen; Sayyam Shah; Angelica Varesi; Jasmine Ryu Won Kang; Alex Murison; Jin-Gyu Cheong; Sven Turkalj; Xuan Zhang; Felix A. Radtke; Tsega-Ab Abera; Isabel N. X. Lim; Liqing Jin; Joana Araújo; Alicia G. Aguilar-Navarro; Darrien Parris; Jessica McLeod; Hyerin Kim; Ho Seok Lee; Lin Zhang; Mason Boulanger; Elyssa Bader; Elias Gbeha; Christopher N. Parkhurst; Elvin Wagenblast; Eugenia Flores-Figueroa; Bo Wang; Gregory W. Schwartz; Leonard D. Shultz; Anna S. Nam; H. Leighton Grimes; Steven Z. Josefowicz; Philip Awadalla; Paresh Vyas; John E. Dick; Stephanie Z. Xie
errShare
errSave
Transposable elements shape stemness in normal and leukemic hematopoiesis
errNature Genetics
IF29
err2026-05-04
err0
errOAAI
errGiacomo Grillo; Bettina Nadorp; Aditi Qamra; Bryce Drylie; Amanda Mitchell; Christopher Arlidge; Ankita Nand; Naoya Takayama; Alex Murison; Seyed Ali Madani Tonekaboni; Komaldeep Kaur Kang; Andrea Arruda; Jean C. Y. Wang; Mark D. Minden; Özgen Deniz; Héléna Boutzen; John E. Dick; Mathieu Lupien
errShare
errSave
Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation
errBlood
IF23.1
err2025-11-18
err0
errOAAI
errTianyi Ling; Cristiana O’Brien; Jonathan R. St-Germain; Vincent Rondeau; Mary Shi; Jacob M. Berman; Adrianna Cepa; Paula Saez Raez; Mark Wunderlich; Katharine M. Carter; Cody Stillwell; Christina Sexton; Rachel Culp-Hill; Julie A. Reisz; Saeer A. Adeel; Andy G. X. Zeng; Suraj Bansal; Emily Tsao; He Tian Chen; John E Dick
errShare
errSave
Multipotent lineage potential in B cell acute lymphoblastic leukemia is associated with distinct cellular origins and clinical features
errNature Cancer
IF28.5
err2025-06-27
err0
PREAI
errIlaria Iacobucci; Andy G. X. Zeng; Qingsong Gao; Laura Garcia-Prat; Pradyumna Baviskar; Sayyam Shah; Alex Murison; Veronique Voisin; Michelle Chan-Seng-Yue; Cheng Cheng; Chunxu Qu; Colin Bailey; Matthew Lear; Matthew T. Witkowski; Xin Zhou; Airen Zaldivar Peraza; Karishma Gangwani; Anjali S. Advani; Selina M. Luger; Mark R. Litzow; Jacob M. Rowe; Elisabeth M. Paietta; Wendy Stock; John E. Dick; Charles G. Mullighan
errShare
errSave
Moving towards genome-wide data integration for patient stratification with Integrate Any Omics
errNATURE MACHINE INTELLIGENCE
IF23.9
err2025-01-23
err1
PREAI
errMa, Shihao; Zeng, Andy G. X.; Haibe-Kains, Benjamin; Goldenberg, Anna; Dick, John E.
errShare
errSave
ATLAS-AML: An Automated Bioinformatics Pipeline for Drug Target Characterization in Acute Myeloid Leukemia
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errBansal, Suraj; Chen, David; Mitchell, Amanda; Zeng, Andy G. X.; Dick, John E.
errShare
errSave
The Exportin, CSE1L, Regulates Ribosome Biogenesis and Is a Selective Dependency in Childhood and Young Adult Acute Myeloid Leukemia
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errEgan, Grace; Kumar, Amit; Voisin, Veronique; Hurren, Rose; Chegini, Ali; Ling, Dakai; Thomas, Geethu Emily; Yan, Youngran; Feng, Yue; Bansal, Suraj; Zeng, Andy G. X.; Arruda, Andrea; Dick, John Edgar; Bader, Gary D.; Minden, Mark D.; Schimmer, Aaron D.
errShare
errSave
Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties
errLEUKEMIA
IF13.4
err2024-08-21
err0
errOAAI
errBoutzen, Helena; Murison, Alex; Oriecuia, Alexa; Bansal, Suraj; Arlidge, Christopher; Wang, Jean C. Y.; Lupien, Mathieu; Kaufmann, Kerstin B.; Dick, John E.
errShare
errSave
Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging
errCELL STEM CELL
IF20.4
err2024-08-01
err6
errOAAI
errJakobsen, Niels Asger; Turkalj, Sven; Zeng, Andy G. X.; Stoilova, Bilyana; Metzner, Marlen; Rahmig, Susann; Nagree, Murtaza S.; Shah, Sayyam; Moore, Rachel; Usukhbayar, Batchimeg; Salazar, Mirian Angulo; Gafencu, Grigore-Aristide; Kennedy, Alison; Newman, Simon; Kendrick, Benjamin J. L.; Taylor, Adrian H.; Afinowi-Luitz, Rasheed; Gundle, Roger; Watkins, Bridget; Wheway, Kim; Beazley, Debra; Murison, Alex; Aguilar-Navarro, Alicia G.; Flores-Figueroa, Eugenia; Dakin, Stephanie G.; Carr, Andrew J.; Nerlov, Claus; Dick, John E.; Xie, Stephanie Z.; Vyas, Paresh
errShare
errSave
Clonal haematopoiesis is associated with major adverse cardiovascular events in patients with hypertrophic cardiomyopathy
errEUROPEAN JOURNAL OF HEART FAILURE
IF10.8
err2024-08-01
err1
errOAAI
errScolari, Fernando L.; Brahmbhatt, Darshan; Abelson, Sagi; Lee, Deacon; Kim, Raymond H.; Pedarzadeh, Ali; Sakhnini, Ali; Adler, Arnon; Chan, Raymond H.; Dick, John E.; Rakowski, Harry; Billia, Filio
errShare
errSave
Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-07-21
err6
errOAAI
errFan, Huihui; Wang, Feng; Zeng, Andy; Murison, Alex; Tomczak, Katarzyna; Hao, Dapeng; Jelloul, Fatima Zahra; Wang, Bofei; Barrodia, Praveen; Liang, Shaoheng; Chen, Ken; Wang, Linghua; Zhao, Zhongming; Rai, Kunal; Jain, Abhinav K. K.; Dick, John; Daver, Naval; Futreal, Andy; Abbas, Hussein A. A.
errShare
errSave
Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
errCANCER DISCOVERY
IF33.3
err2023-05-16
err6
errOAAI
errKan, Winnie L.; Dhagat, Urmi; Kaufmann, Kerstin B.; Hercus, Timothy R.; Nero, Tracy L.; Zeng, Andy G. X.; Toubia, John; Barry, Emma F.; Broughton, Sophie E.; Gomez, Guillermo A.; Benard, Brooks A.; Dottore, Mara; Shing, Karen S. Cheung Tung; Boutzen, Helena; Samaraweera, Saumya E.; Simpson, Kaylene J.; Jin, Liqing; Goodall, Gregory J.; Begley, C. Glenn; Thomas, Daniel; Ekert, Paul G.; Tvorogov, Denis; D'Andrea, Richard J.; Dick, John E.; Parker, Michael W.; Lopez, Angel F.
errShare
errSave
Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity
errHAEMATOLOGICA
IF7.9
err2023-04-06
err19
errOAAI
errO'Brien, Cristiana; Ling, Tianyi; Berman, Jacob M.; Culp-Hill, Rachel; Reisz, Julie A.; Rondeau, Vincent; Jahangiri, Soheil; St-Germain, Jonathan; Macwan, Vinitha; Astori, Audrey; Zeng, Andy; Hong, Jun Young; Li, Meng; Yang, Min; Jana, Sadhan; Gamboni, Fabia; Tsao, Emily; Liu, Weiyi; Dick, John E.; Lin, Hening; Melnick, Ari; Tikhonova, Anastasia; Arruda, Andrea; Minden, Mark D.; Raught, Brian; D'Alessandro, Angelo; Jones, Courtney L.
errShare
errSave
Hematopoietic cell fate and the initiation of leukemic properties in primitive primary human cells are influenced by Ras activity and farnesyltransferase inhibition
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err35
errOAAI
errDorrell, C; Takenaka, K; Minden, MD; Hawley, RG; Dick, JE
errShare
errSave
In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
errBLOOD CANCER DISCOVERY
IF11.5
err2023-02-09
err8
errOAAI
errVujovic, Ana; de Rooij, Laura; Chahi, Ava Keyvani; Chen, He Tian; Yee, Brian A.; Loganathan, Sampath K.; Liu, Lina; Chan, Derek C. H.; Tajik, Amanda; Tsao, Emily; Moreira, Steven; Joshi, Pratik; Xu, Joshua; Wong, Nicholas; Balde, Zaldy; Jahangiri, Soheil; Zandi, Sasan; Aigner, Stefan; Dick, John E.; Minden, Mark D.; Schramek, Daniel; Yeo, Gene W.; Hope, Kristin J.
errShare
errSave
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition
errLEUKEMIA
IF13.4
err2023-01-31
err9
errOAAI
errBoila, Liberalis Debraj; Ghosh, Subhadeep; Bandyopadhyay, Subham K.; Jin, Liqing; Murison, Alex; Zeng, Andy G. X.; Shaikh, Wasim; Bhowmik, Satyaki; Muddineni, Siva Sai Naga Anurag; Biswas, Mayukh; Sinha, Sayantani; Chatterjee, Shankha Subhra; Mbong, Nathan; Gan, Olga I.; Bose, Anwesha; Chakraborty, Sayan; Arruda, Andrea; Kennedy, James A.; Mitchell, Amanda; Lechman, Eric R.; Banerjee, Debasis; Milyavsky, Michael; Minden, Mark D.; Dick, John E.; Sengupta, Amitava
errShare
errSave
Clonal hematopoiesis confers an increased mortality risk in orthotopic heart transplant recipients
errAMERICAN JOURNAL OF TRANSPLANTATION
IF8.2
err2022-12-01
err13
errOAAI
errScolari, Fernando L.; Brahmbhatt, Darshan H.; Abelson, Sagi; Medeiros, Jessie J. F.; Anker, Markus S.; Fung, Nicole L.; Otsuki, Madison; Calvillo-Arguelles, Oscar; Lawler, Patrick R.; Ross, Heather J.; Luk, Adriana C.; Anker, Stefan; Dick, John E.; Billia, Filio
errShare
errSave
Clinical significance of clonal hematopoiesis in the setting of autologous stem cell transplantation for lymphoma
errAMERICAN JOURNAL OF HEMATOLOGY
IF9.9
err2022-09-26
err10
PREAI
errLackraj, Tracy; Ben Barouch, Sharon; Medeiros, Jessie J. F.; Pedersen, Stephanie; Danesh, Arnavaz; Bakhtiari, Mehran; Hong, Michael; Tong, Kit; Joynt, Jesse; Arruda, Andrea; Minden, Mark D.; Kuruvilla, John; Bhella, Sita; Kukreti, Vishal; Crump, Michael; Prica, Anca; Chen, Christine; Deng, Yangqing; Xu, Wei; Pugh, Trevor J.; Keating, Armand; Dick, John E.; Abelson, Sagi; Kridel, Robert
errShare
errSave
A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome
errLEUKEMIA
IF13.4
err2022-09-21
err6
errOAAI
errBoutzen, Helena; Tonekaboni, Seyed Ali Madani; Chan-Seng-Yue, Michelle; Murison, Alex; Takayama, Naoya; Mbong, Nathan; Wagenblast, Elvin; Orouji, Elias; Arruda, Andrea; Mitchell, Amanda; Notta, Faiyaz; Minden, Mark D.; Lupien, Mathieu; Kaufmann, Kerstin B.; Dick, John E.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Nico van Rooijen
H-index: 165 · Papers: 1.0K
S
Stefan D. Anker
H-index: 162 · Papers: 1.2K
T
Tony Pawson
H-index: 157 · Papers: 751
P
Peter Valent
H-index: 131 · Papers: 1.5K
L
Linghua Wang
H-index: 128 · Papers: 831
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