Po‐Ru Loh - Publications, H-index & Citations

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Po‐Ru Loh

Broad Institute of MIT and Harvard

63H-index

190Paper Count

5.2WCitation Count

Published Papers 70

Publication Date

Correlations between causal effect sizes of proximal SNPs vary with functional annotations and implicate stabilizing selection

Nature Genetics

IF29

2026-08-13

PREAI

Martin Jinye Zhang; Arun Durvasula; Colby Chiang; Evan M. Koch; Benjamin J. Strober; Huwenbo Shi; Alison R. Barton; Samuel S. Kim; Omer Weissbrod; Po-Ru Loh; Steven Gazal; Shamil Sunyaev; Alkes L. Price

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Patterns and drivers of 43,617 mosaic chromosomal alterations in blood

Nature Genetics

IF29

2026-05-19

OAAI

David Tang; Nolan Kamitaki; Ronen E. Mukamel; Simone Rubinacci; Po-Ru Loh

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The DNA virome varies with human genes and environments

Nature

IF48.5

2026-03-25

OAAI

Nolan Kamitaki; David Tang; Steven A. McCarroll; Po-Ru Loh

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Human and bacterial genetic variation shape oral microbiomes and health

Nature

IF48.5

2026-01-28

OAAI

Nolan Kamitaki; Robert E. Handsaker; Margaux L. A. Hujoel; Ronen E. Mukamel; Christina L. Usher; Steven A. McCarroll; Po-Ru Loh

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Insights into DNA repeat expansions among 900,000 biobank participants

Nature

IF48.5

2026-01-07

OAAI

Margaux L. A. Hujoel; Robert E. Handsaker; David Tang; Nolan Kamitaki; Ronen E. Mukamel; Simone Rubinacci; Pier Francesco Palamara; Steven A. McCarroll; Po-Ru Loh

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Plasma Proteins Invariant to Diet in Celiac Disease: Results From a Proteomics Study on the UK Biobank

Gastro Hep Advances

IF0

2025-10-01

OAAI

Hujoel, Isabel A.; Loh, Po-Ru; Hujoel, Margaux L. A.

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The Somatic Mosaicism across Human Tissues Network

Nature

IF48.5

2025-07-02

PREAI

Tim H. H. Coorens; Ji Won Oh; Yujin Angelina Choi; Nam Seop Lim; Boxun Zhao; Adam Voshall; Alexej Abyzov; Lucinda Antonacci-Fulton; Samuel Aparicio; Kristin G. Ardlie; Thomas J. Bell; James T. Bennett; Bradley E. Bernstein; Thomas G. Blanchard; Alan P. Boyle; Jason D. Buenrostro; Kathleen H. Burns; Fei Chen; Rui Chen; Sangita Choudhury; Harsha V. Doddapaneni; Evan E. Eichler; Gilad D. Evrony; Melissa A. Faith; Thomas G. Fazzio; Robert S. Fulton; Manuel Garber; Nils Gehlenborg; Soren Germer; Gad Getz; Richard A. Gibbs; Raquel G. Hernandez; Fulai Jin; Jan O. Korbel; Dan A. Landau; Heather A. Lawson; Niall J. Lennon; Heng Li; Yan Li; Po-Ru Loh; Gabor Marth; Michael J. McConnell; Ryan E. Mills; Stephen B. Montgomery; Pradeep Natarajan; Peter J. Park; Rahul Satija; Fritz J. Sedlazeck; Diane D. Shao; Hui Shen; Andrew B. Stergachis; Hunter R. Underhill; Alexander E. Urban; Melissa W. VonDran; Christopher A. Walsh; Ting Wang; Tao P. Wu; Chenghang Zong; Eunjung Alice Lee; Flora M. Vaccarino

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Identifying genetic variants that influence the abundance of cell states in single-cell data

NATURE GENETICS

IF31.8

2024-09-26

PREAI

Rumker, Laurie; Sakaue, Saori; Reshef, Yakir; Kang, Joyce B.; Yazar, Seyhan; Alquicira-Hernandez, Jose; Valencia, Cristian; Lagattuta, Kaitlyn A.; Mah-Som, Annelise; Nathan, Aparna; Powell, Joseph E.; Loh, Po-Ru; Raychaudhuri, Soumya

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Protein-altering variants at copy number-variable regions influence diverse human phenotypes

NATURE GENETICS

IF31.8

2024-03-28

OAAI

Hujoel, Margaux L. A.; Handsaker, Robert E.; Sherman, Maxwell A.; Kamitaki, Nolan; Barton, Alison R.; Mukamel, Ronen E.; Terao, Chikashi; Mccarroll, Steven A.; Loh, Po-Ru

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Uncovering complex trait heritability hidden in the repeatome

CELL GENOMICS

IF9

2023-12-01

OAAI

Loh, Po-Ru

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A pan-tissue survey of mosaic chromosomal alterations in 948 individuals

NATURE GENETICS

IF31.8

2023-10-30

OAAI

Gao, Teng; Kastriti, Maria Eleni; Ljungstrom, Viktor; Heinzel, Andreas; Tischler, Arthur S.; Oberbauer, Rainer; Loh, Po-Ru; Adameyko, Igor; Park, Peter J.; Kharchenko, Peter V.

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Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

CELL GENOMICS

IF9

2023-08-01

OAAI

Maury, Eduardo A.; Sherman, Maxwell A.; Genovese, Giulio; Gilgenast, Thomas G.; Kamath, Tushar; Burris, S. J.; Rajarajan, Prashanth; Flaherty, Erin; Akbarian, Schahram; Chess, Andrew; McCarroll, Steven A.; Loh, Po-Ru; Phillips-Cremins, Jennifer E.; Brennand, Kristen J.; Macosko, Evan Z.; Walters, James T. R.; O'Donovan, Michael; Sullivan, Patrick; Sebat, Jonathan; Lee, Eunjung A.; Walsh, Christopher A.

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The lingering effects of Neanderthal introgression on human complex traits

ELIFE

IF0

2023-03-20

OAAI

Wei, Xinzhu; Robles, Christopher R.; Pazokitoroudi, Ali; Ganna, Andrea; Gusev, Alexander; Durvasula, Arun; Gazal, Steven; Loh, Po-Ru; Reich, David; Sankararaman, Sriram

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Haplotype-aware analysis of somatic copy number variations from single -cell transcriptomes

NATURE BIOTECHNOLOGY

IF41.7

2022-09-26

PREAI

Gao, Teng; Soldatov, Ruslan; Sarkar, Hirak; Kurkiewicz, Adam; Biederstedt, Evan; Loh, Po-Ru; Kharchenko, Peter, V

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Chromosomal phase improves aneuploidy detection in non-invasive prenatal testing at low fetal DNA fractions

SCIENTIFIC REPORTS

IF3.9

2022-07-14

OAAI

Genovese, Giulio; Mello, Curtis J.; Loh, Po-Ru; Handsaker, Robert E.; Kashin, Seva; Whelan, Christopher W.; Bayer-Zwirello, Lucy A.; McCarroll, Steven A.

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Incorporating family history of disease improves polygenic risk scores in diverse populations

CELL GENOMICS

IF9

2022-07-01

OAAI

Hujoel, Margaux L. A.; Loh, Po-Ru; Neale, Benjamin M.; Price, Alkes L.

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A spectrum of recessiveness among Mendelian disease variants in UK Biobank

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2022-07-01

OAAI

Barton, Alison R.; Hujoel, Margaux L. A.; Mukamel, Ronen E.; Sherman, Maxwell A.; Loh, Po-Ru

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Genome-wide mapping of somatic mutation rates uncovers drivers of cancer

NATURE BIOTECHNOLOGY

IF41.7

2022-06-20

OAAI

Sherman, Maxwell A.; Yaari, Adam U.; Priebe, Oliver; Dietlein, Felix; Loh, Po-Ru; Berger, Bonnie

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Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets

NATURE COMMUNICATIONS

IF15.7

2021-10-18

OAAI

Marquez-Luna, Carla; Gazal, Steven; Loh, Po-Ru; Kim, Samuel S.; Furlotte, Nicholas; Auton, Adam; Price, Alkes L.

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GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health

NATURE COMMUNICATIONS

IF15.7

2021-07-07

OAAI

Zhao, Yajie; Stankovic, Stasa; Koprulu, Mine; Wheeler, Eleanor; Day, Felix R.; Allen, Hana Lango; Kerrison, Nicola D.; Pietzner, Maik; Loh, Po-Ru; Wareham, Nicholas J.; Langenberg, Claudia; Ong, Ken K.; Perry, John R. B.

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Research Directions