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Inclusion of a retroviral protease enhances the immunogenicity of VLP-forming mRNA vaccines against HIV-1 or SARS-CoV-2 in mice Zhang, Peng; Singh, Mamta; Becker, Vada A.; Croft, Jacob; Tsybovsky, Yaroslav; Gopan, Vinay; Seo, Yuna; Liu, Qingbo; Rogers, Denise; Miao, Huiyi; Lin, Yin; Rogan, Daniel; Shields, Courtney; Elbashir, Sayda M.; Calabrese, Samantha; Renzi, Isabella; Preznyak, Vladimir; Narayanan, Elizabeth; Stewart-Jones, Guillaume; Himansu, Sunny; Connors, Mark; Lee, Kelly; Carfi, Andrea; Lusso, Paolo Share Save
PET imaging of HIV-1 envelope protein gp120 using 18F-labeled nanobodies Martinez-Orengo, Neysha; Shah, Swati; Lai, Jianhao; Basuli, Falguni; Lyndaker, Anna; Turner, Mitchell L.; Peiravi, Morteza; Sourabh, Suman; Sampson, Kevon; Zhang, Peng; Swenson, Rolf E.; Lusso, Paolo; Maldarelli, Frank; Nath, Avindra; Lau, Chuen-Yen; Hammoud, Dima A. Share Save
Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation Zhang, Peng; Gorman, Jason; Tsybovsky, Yaroslav; Lu, Maolin; Liu, Qingbo; Gopan, Vinay; Singh, Mamta; Lin, Yin; Miao, Huiyi; Seo, Yuna; Kwon, Alice; Olia, Adam S.; Chuang, Gwo-Yu; Geng, Hui; Lai, Yen-Ting; Zhou, Tongqing; Mascola, John R.; Mothes, Walther; Kwong, Peter D.; Lusso, Paolo Share Save
Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus- like particles Zhang, Peng; Falcone, Samantha; Tsybovsky, Yaroslav; Singh, Mamta; Gopan, Vinay; Miao, Huiyi; Seo, Yuna; Rogers, Denise; Renzi, Isabella; Lai, Yen-Ting; Narayanan, Elisabeth; Stewart-Jones, Guillaume; Himansu, Sunny; Carfi, Andrea; Fauci, Anthony S.; Lusso, Paolo Share Save
Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters Liu, Xueqiao; Park, Hong-Su; Matsuoka, Yumiko; Santos, Celia; Yang, Lijuan; Luongo, Cindy; Moore, Ian N.; Johnson, Reed F.; Garza, Nicole L.; Zhang, Peng; Lusso, Paolo; Best, Sonja M.; Buchholz, Ursula J.; Le Nouen, Cyril Share Save
Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain Kwon, Young D.; Pegu, Amarendra; Yang, Eun Sung; Zhang, Baoshan; Bender, Michael F.; Asokan, Mangaiarkarasi; Liu, Qingbo; McKee, Krisha; Lin, Bob C.; Liu, Tracy; Louder, Mark K.; Rawi, Reda; Reveiz, Mateo; Schaub, Andrew J.; Shen, Chen-Hsiang; Doria-Rose, Nicole A.; Lusso, Paolo; Mascola, John R.; Kwong, Peter D. Share Save
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Anti-PF4 antibodies associated with disease severity in COVID-19 Liu, Qingbo; Miao, Huiyi; Li, Shuai; Zhang, Peng; Gerber, Gloria F.; Follmann, Dean; Ji, Hongkai; Zeger, Scott L.; Chertow, Daniel S.; Quinn, Thomas C.; Robinson, Matthew L.; Kickler, Thomas S.; Rothman, Richard E.; Fenstermacher, Katherine Z. J.; Braunstein, Evan M.; Cox, Andrea L.; Farci, Patrizia; Fauci, Anthony S.; Lusso, Paolo Share Save
Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants Chen, Zhaochun; Zhang, Peng; Matsuoka, Yumiko; Tsybovsky, Yaroslav; West, Kamille; Santos, Celia; Boyd, Lisa F.; Nguyen, Hanh; Pomerenke, Anna; Stephens, Tyler; Olia, Adam S.; Zhang, Baoshan; De Giorgi, Valeria; Holbrook, Michael R.; Gross, Robin; Postnikova, Elena; Garza, Nicole L.; Johnson, Reed F.; Margulies, David H.; Kwong, Peter D.; Alter, Harvey J.; Buchholz, Ursula J.; Lusso, Paolo; Farci, Patrizia Share Save
A multiclade env-gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques Zhang, Peng; Narayanan, Elisabeth; Liu, Qingbo; Tsybovsky, Yaroslav; Boswell, Kristin; Ding, Shilei; Hu, Zonghui; Follmann, Dean; Lin, Yin; Miao, Huiyi; Schmeisser, Hana; Rogers, Denise; Falcone, Samantha; Elbashir, Sayda M.; Presnyak, Vladimir; Bahl, Kapil; Prabhakaran, Madhu; Chen, Xuejun; Sarfo, Edward K.; Ambrozak, David R.; Gautam, Rajeev; Martin, Malcom A.; Swerczek, Joanna; Herbert, Richard; Weiss, Deborah; Misamore, Johnathan; Ciaramella, Giuseppe; Himansu, Sunny; Stewart-Jones, Guillaume; McDermott, Adrian; Koup, Richard A.; Mascola, John R.; Finzi, Andres; Carfi, Andrea; Fauci, Anthony S.; Lusso, Paolo Share Save
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Rational Engraftment of Quaternary-Interactive Acidic Loops for Anti-HIV-1 Antibody Improvement Liu, Qingbo; Zhang, Peng; Miao, Huiyi; Lin, Yin; Do Kwon, Young; Kwong, Peter D.; Rikhtegaran-Tehrani, Zahra; Seaman, Michael S.; DeVico, Anthony L.; Sajadi, Mohammad M.; Lusso, Paolo Share Save
Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State Zhang, Peng; Kwon, Alice L.; Guzzo, Christina; Liu, Qingbo; Schmeisser, Hana; Miao, Huiyi; Lin, Yin; Cimbro, Raffaello; Huang, Jinghe; Connors, Mark; Schmidt, Stephen D.; Dolan, Michael A.; Armstrong, Anthony A.; Lusso, Paolo Share Save
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HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions Easterhoff, David; Pollara, Justin; Luo, Kan; Janus, Benjamin; Gohain, Neelakshi; Williams, LaTonya D.; Tay, Matthew Zirui; Monroe, Anthony; Peachman, Kristina; Choe, Misook; Min, Susie; Lusso, Paolo; Zhang, Peng; Go, Eden P.; Desaire, Heather; Bonsignori, Mattia; Hwang, Kwan-Ki; Beck, Charles; Kakalis, Matina; O'Connell, Robert J.; Vasan, Sandhya; Kim, Jerome H.; Michael, Nelson L.; Excler, Jean-Louis; Robb, Merlin L.; Rerks-Ngarm, Supachai; Kaewkungwal, Jaranit; Pitisuttithum, Punnee; Nitayaphan, Sorachai; Sinangil, Faruk; Tartaglia, James; Phogat, Sanjay; Wiehe, Kevin; Saunders, Kevin O.; Montefiori, David C.; Tomaras, Georgia D.; Moody, M. Anthony; Arthos, James; Rao, Mangala; Joyce, M. Gordon; Ofek, Gilad; Ferrari, Guido; Haynes, Barton F. Share Save
Improvement of antibody functionality by structure-guided paratope engraftment Liu, Qingbo; Lai, Yen-Ting; Zhang, Peng; Louder, Mark K.; Pegu, Amarendra; Rawi, Reda; Asokan, Mangaiarkarasi; Chen, Xuejun; Shen, Chen-Hsiang; Chuang, Gwo-Yu; Yang, Eun Sung; Miao, Huiyi; Wang, Yuge; Fauci, Anthony S.; Kwong, Peter D.; Mascola, John R.; Lusso, Paolo Share Save
Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation Guzzo, Christina; Zhang, Peng; Liu, Qingbo; Kwon, Alice L.; Uddin, Ferzan; Wells, Alexandra I.; Schmeisser, Hana; Cimbro, Raffaello; Huang, Jinghe; Doria-Rose, Nicole; Schmidt, Stephen D.; Dolan, Michael A.; Connors, Mark; Mascola, John R.; Lusso, Paolo Share Save
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