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Three-dimensional genome landscape of primary human cancers Yost, Kathryn E.; Zhao, Yanding; Hung, King L.; Zhu, Kaiyuan; Xu, Duo; Corces, M. Ryan; Shams, Shadi; Louie, Bryan H.; Sarmashghi, Shahab; Sundaram, Laksshman; Luebeck, Jens; Clarke, Stanley; Doane, Ashley S.; Granja, Jeffrey M.; Choudhry, Hani; Imielinski, Marcin; Cherniack, Andrew D.; Khurana, Ekta; Bafna, Vineet; Felau, Ina; Zenklusen, Jean C.; Laird, Peter W.; Curtis, Christina; Greenleaf, William J.; Chang, Howard Y. Share Save
Molecular characterization of HER2-negative breast cancers reveals a distinct patient subgroup with 17q12 deletion and heterozygous loss of ERBB2 Qiu, X.; Tarantino, P.; Li, R.; Grinshpun, A.; Gupta, H.; Hughes, M. E.; Kirkner, G.; Scholl, L.; Johnson, B. E.; Meyerson, M.; Cherniack, A. D.; Jiang, Y.; Zhou, N.; Lin, N. U.; Long, H. W.; Tolaney, S. M.; Jeselsohn, R. Share Save
Classification of non-TCGA cancer samples to TCGA molecular subtypes using compact feature sets Ellrot, Kyle; Wong, Christopher K.; Yau, Christina; Castro, Mauro A. A.; Lee, Jordan A.; Karlberg, Brian J.; Grewal, Jasleen K.; Lagani, Vincenzo; Tercan, Bahar; Friedl, Verena; Hinoue, Toshinori; Uzunangelov, Vladislav; Westlake, Lindsay; Loinaz, Xavier; Felau, Ina; Wang, Peggy I.; Kemal, Anab; Caesar-Johnson, Samantha J.; Shmulevich, Ilya; Lazar, Alexander J.; Tsamardinos, Ioannis; Hoadley, Katherine A.; Robertson, A. Gordon; Knijnenburg, Theo A.; Benz, Christopher C.; Stuart, Joshua M.; Zenklusen, Jean C.; Cherniack, Andrew D.; Laird, Peter W. Share Save
Intrapatient variation in PD-L1 expression and tumor mutational burden and the impact on outcomes to immune checkpoint inhibitor therapy in patients with non-small-cell lung cancer Di Federico, A.; Alden, S. L.; Smithy, J. W.; Ricciuti, B.; Alessi, J. V.; Wang, X.; Pecci, F.; Lamberti, G.; Gandhi, M. M.; Vaz, V. R.; Spurr, L. F.; Sholl, L. M.; Pfaff, K. L.; Rodig, S. J.; Li, Y. Y.; Cherniack, A. D.; Nishino, M.; Johnson, B. E.; Awad, M. M. Share Save
Molecular profiling of 888 pediatric tumors informs future precision trials and data-sharing initiatives in pediatric cancer (vol 15, 5837, 2024) Forrest, Suzanne J.; Gupta, Hersh; Ward, Abigail; Li, Yvonne Y.; Doan, Duong; Al-Ibraheemi, Alyaa; Alexandrescu, Sanda; Bandopadhayay, Pratiti; Shusterman, Suzanne; Mullen, Elizabeth A.; Collins, Natalie B.; Chi, Susan N.; Wright, Karen D.; Kumari, Priti; Mazor, Tali; Ligon, Keith L.; Shivdasani, Priyanka; Manam, Monica; MacConaill, Laura E.; Ceca, Evelina; Benich, Sidney N.; London, Wendy B.; Schilsky, Richard L.; Bruinooge, Suanna S.; Guidry Auvil, Jaime M.; Cerami, Ethan; Rollins, Barrett J.; Meyerson, Matthew L.; Lindeman, Neal I.; Johnson, Bruce E.; Cherniack, Andrew D.; Church, Alanna J.; Janeway, Katherine A. Share Save
Contemporary prognostic signatures and refined risk stratification of gliomas: An analysis of 4400 tumors Ghosh, Hia S.; Patel, Ruchit, V; Woodward, Eleanor; Greenwald, Noah F.; Bhave, Varun M.; Maury, Eduardo A.; Cello, Gregory; Hoffman, Samantha E.; Li, Yvonne; Gupta, Hersh; Youssef, Gilbert; Spurr, Liam F.; Vogelzang, Jayne; Touat, Mehdi; Dubois, Frank; Cherniack, Andrew D.; Guo, Xiaopeng; Tavakol, Sherwin; Cioffi, Gino; Lindeman, Neal, I; Ligon, Azra H.; Chiocca, E. Antonio; Reardon, David A.; Wen, Patrick Y.; Meredith, David M.; Santagata, Sandro; Barnholtz-Sloan, Jill S.; Ligon, Keith L.; Beroukhim, Rameen; Bi, Wenya Linda Share Save
Molecular profiling of 888 pediatric tumors informs future precision trials and data-sharing initiatives in pediatric cancer Forrest, Suzanne J.; Gupta, Hersh; Ward, Abigail; Li, Yvonne Y.; Doan, Duong; Al-Ibraheemi, Alyaa; Alexandrescu, Sanda; Bandopadhayay, Pratiti; Shusterman, Suzanne; Mullen, Elizabeth A.; Collins, Natalie B.; Chi, Susan N.; Wright, Karen D.; Kumari, Priti; Mazor, Tali; Ligon, Keith L.; Shivdasani, Priyanka; Manam, Monica; MacConaill, Laura E.; Ceca, Evelina; Benich, Sidney N.; London, Wendy B.; Schilsky, Richard L.; Bruinooge, Suanna S.; Auvil, Jaime M. Guidry; Cerami, Ethan; Rollins, Barrett J.; Meyerson, Matthew L.; Lindeman, Neal I.; Johnson, Bruce E.; Cherniak, Andrew D.; Church, Alanna J.; Janeway, Katherine A. Share Save
Velcrin molecular glues induce apoptosis in glioblastomas with high PDE3A and SLFN12 expression Aquilanti, Elisa; Goldoni, Silvia; Baker, Andrew; Kotynkova, Kristyna; Andersen, Sawyer; Bozinov, Vincent; Gao, Galen F.; Cherniack, Andrew D.; Lange, Martin; Lesche, Ralf; Kopitz, Charlotte; Lienau, Philip; Lewis, Timothy A.; Garrido, Marine; Gradl, Stefan; Seidel, Henrik; Tseng, Yuen-Yi; Ligon, Keith L.; Wen, Patrick Y.; Meyerson, Matthew; Greulich, Heidi Share Save
Impact of HER2 expression dynamics on the realworld activity of trastuzumab deruxtecan for metastatic breast cancer (RELIEVE) Tarantino, Paolo; Hughes, Melissa; Kusmick, Ross; Alder, Laura; Pereslete, Alyssa; Noteware, Laura; Moore, Heather; Van Swearingen, Amanda; Li, Tianyu; Gupta, Hersh; Smith, Kalie; Morganti, Stefania; Files, Janet; Sendrick, Kerry; Buck, Simone; Dillon, Deborah; Jeselsohn, Rinath; Li, Yvonne; Cherniack, Andrew; Prat, Aleix; Chan, Nay Nwe Nyein; Rimm, David; Curigliano, Giuseppe; Sammons, Sarah; Anders, Carey; Lin, Nancy; Tolaney, Sara Share Save
Predictors of exceptional response to first line HER2-targeted therapy for metastatic breast cancer Morganti, Stefania; Li, Tianyu; Santos, Katheryn; Hughes, Melissa; Priedigkeit, Nolan; Li, Yvonne; Lipsyc-Sharf, Marla; Kirkner, Gregory; Files, Janet; Kasparian, Julie; Grant, Elizabeth; Gupta, Gunjan; Curigliano, Giuseppe; Tolaney, Sara; Cherniack, Andrew; Tayob, Nabihah; Lin, Nancy; Parsons, Heather Share Save
Comprehensive clinicogenomic characterization of inflammatory breast cancer Priedigkeit, Nolan; Harrison, Beth; Hughes, Melissa; Shue, Robert; Li, Yvonne; Kirkner, Gregory; Remolano, Claire; Strauss, Sarah; Files, Janet; Feeney, Anne-Marie; Mohammed-Abreu, Ayesha; Garrido-Castro, Ana; Barroso-Sousa, Romualdo; Bychkovsky, Brittany; Nakhlis, Faina; Bellon, Jennifer; King, Tari; Johnson, Bruce; Sholl, Lynette; Dillon, Deborah; Overmoyer, Beth; Tolaney, Sara; Cherniack, Andrew; Lin, Nancy; Lynce, Filipa Share Save
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants (Vol 15, 2742, 2024) Hayes, Tikvah K.; Aquilanti, Elisa; Persky, Nicole S.; Yang, Xiaoping; Kim, Erica E.; Brenan, Lisa; Goodale, Amy B.; Alan, Douglas; Sharpe, Ted; Shue, Robert E.; Westlake, Lindsay; Golomb, Lior; Silverman, Brianna R.; Morris, Myshal D.; Fisher, Ty Running; Beyene, Eden; Li, Yvonne Y.; Cherniack, Andrew D.; Piccioni, Federica; Hicks, J. Kevin; Chi, Andrew S.; Cahill, Daniel P.; Dietrich, Jorg; Batchelor, Tracy T.; Root, David E.; Johannessen, Cory M.; Meyerson, Matthew Share Save
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants Hayes, Tikvah K.; Aquilanti, Elisa; Persky, Nicole S.; Yang, Xiaoping; Kim, Erica E.; Brenan, Lisa; Goodale, Amy B.; Alan, Douglas; Sharpe, Ted; Shue, Robert E.; Westlake, Lindsay; Golomb, Lior; Silverman, Brianna R.; Morris, Myshal D.; Fisher, Ty Running; Beyene, Eden; Li, Yvonne Y.; Cherniack, Andrew D.; Piccioni, Federica; Hicks, J. Kevin; Chi, Andrew S.; Cahill, Daniel P.; Dietrich, Jorg; Batchelor, Tracy T.; Root, David E.; Johannessen, Cory M.; Meyerson, Matthew Share Save
Deep mutational scanning of EGFR reveals potential domain-specific TKI sensitivities in lung cancer and glioblastoma Hayes, Tikvah; Aquilanti, Elisa; Kim, Erica; Persky, Nicole; Brenan, Lisa; Goodale, Amy; Sharpe, Ted; Alan, Doug; Shue, Robert; Golomb, Lior; Silverman, Brianna; Li, Yvonne; Westlake, Lindsay; Piccioni, Federica; Cherniack, Andrew; Yang, Xiaoping Yang; Root, David; Hicks, J. Kevin; Chi, Andrew; Dietrich, Jorg; Cahill, Daniel; Johannessen, Cory; Batchelor, Tracy; Meyerson, Matthew Share Save
RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer Singh, Harshabad; Sahgal, Pranshu; Kapner, Kevin; Corsello, Steven M.; Gupta, Hersh; Gujrathi, Rahul; Li, Yvonne Y.; Cherniack, Andrew D.; El Alam, Raquelle; Kerfoot, Joseph; Andrews, Elizabeth; Lee, Annette; Nambiar, Chetan; Hannigan, Alison M.; Remland, Joshua; Brais, Lauren; Leahy, Meghan E.; Rubinson, Douglas A.; Schlechter, Benjamin L.; Meyerson, Matthew; Kuang, Yanan; Paweletz, Cloud P.; Lee, Jessica K.; Quintanilha, Julia C. F.; Aguirre, Andrew J.; Perez, Kimberly J.; Huffman, Brandon M.; Rossi, Humberto; Abrams, Thomas A.; Kabraji, Sheheryar; Trusolino, Livio; Bertotti, Andrea; Sicinska, Ewa T.; Parikh, Aparna R.; Wolpin, Brian M.; Schrock, Alexa B.; Giannakis, Marios; Ng, Kimmie; Meyerhardt, Jeffrey A.; Hornick, Jason L.; Sethi, Nilay S.; Cleary, James M. Share Save
XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells Zou, Tao; Zhou, Meng; Gupta, Akansha; Zhuang, Patrick; Fishbein, Alyssa R.; Wei, Hope Y.; Capcha-Rodriguez, Diego; Zhang, Zhouwei; Cherniack, Andrew D.; Meyerson, Matthew Share Save
XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells Zou, Tao; Zhou, Meng; Gupta, Akansha; Zhuang, Patrick; Fishbein, Alyssa R.; Wei, Hope Y.; Capcha-Rodriguez, Diego; Zhang, Zhouwei; Cherniack, Andrew D.; Meyerson, Matthew Share Save
Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer (vol 14, 7496, 2023) Tarantino, Paolo; Gupta, Hersh; Hughes, Melissa E.; Files, Janet; Strauss, Sarah; Kirkner, Gregory; Feeney, Anne-Marie; Li, Yvonne; Garrido-Castro, Ana C.; Barroso-Sousa, Romualdo; Bychkovsky, Brittany L.; DiLascio, Simona; Sholl, Lynette; MacConaill, Laura; Lindeman, Neal; Johnson, Bruce E.; Meyerson, Matthew; Jeselsohn, Rinath; Qiu, Xintao; Li, Rong; Long, Henry; Winer, Eric P.; Dillon, Deborah; Curigliano, Giuseppe; Cherniack, Andrew D.; Tolaney, Sara M.; Lin, Nancy U. Share Save
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