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T

Timothy E. Sweeney

inflammatix

39H-index
152Paper Count
6.1KCitation Count
Published Papers 73
Publication Date
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Real-world clinical evaluation of the Inflammatix TriVerity test for sepsis at the emergency department: an Acutelines study
errInternal and Emergency Medicine
IF3.8
err2026-07-08
err0
errOAAI
errMichèle A. ter Voert; Jingyi Lu; Carolina Hincapié-Osorno; Tamar J. van der Aart; Sanne Ter Horst; Mehtap Ünal; Martje Visser; Raymond J. van Wijk; Jan ter Maaten; Natalie N. Whitfield; Purvesh Khatri; Timothy E. Sweeney; Fredrike Blokzijl; Jie Li; Hjalmar R. Bouma
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Neutrophil dysregulation differentiates pediatric septic shock biomarker-based mortality-risk strata: insights from weighted gene co-expression network and transcriptomic analyses
errFrontiers in Immunology
IF5.9
err2025-11-19
err0
errOAAI
errLeland Dunwoodie; Min Huang; Andrew R. Moore; Natalja L. Stanski; Stephen W. Standage; Jennifer M. Kaplan; Basilia Zingarelli; Kelli Harmon; Julie C. Fitzgerald; Scott L. Weiss; Michael T. Bigham; Adam J. Schwarz; Riad Lutfi; Neal J. Thomas; Bereketeab Haileselassie; Parag N. Jain; Timothy E. Sweeney; Rishikesan Kamaleswaran; Mihir R. Atreya†; Andrew J. Lautz† for the Sepsis Genomics Collaborative
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International multi-cohort analysis identifies novel framework for quantifying immune dysregulation in sepsis with prognostic and therapeutic significance
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errMoore, Andrew R.; Zheng, Hong; Ganesan, Ananthakrishnan; Hasin-Brumshtein, Yehudit; Sweeney, Timothy E.; Rogers, Angela J.; Khatri, Purvesh
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Author Correction: A consensus immune dysregulation framework for sepsis and critical illnesses
errNature Medicine
IF50
err2025-10-27
err0
errOAAI
errAndrew R. Moore; Hong Zheng; Ananthakrishnan Ganesan; Yehudit Hasin-Brumshtein; Manoj V. Maddali; Joseph E. Levitt; Tom van der Poll; Jingyi Lu; Hjalmar R. Bouma; Brendon P. Scicluna; Evangelos J. Giamarellos-Bourboulis; Antigone Kotsaki; Ignacio Martin-Loeches; Alexis Garduno; Jeremiah Hinson; Richard E. Rothman; Jonathan Sevransky; David W. Wright; Mihir R. Atreya; Lyle L. Moldawer; Philip A. Efron; Marcela Kralovcova; Thomas Karvunidis; Heather M. Giannini; Nuala J. Meyer; Timothy E. Sweeney; Angela J. Rogers; Purvesh Khatri
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A consensus immune dysregulation framework for sepsis and critical illnesses
errNature Medicine
IF50
err2025-09-30
err0
errOAAI
errAndrew R. Moore; Hong Zheng; Ananthakrishnan Ganesan; Yehudit Hasin-Brumshtein; Manoj V. Maddali; Joseph E. Levitt; Tom van der Poll; Jingyi Lu; Hjalmar R. Bouma; Brendon P. Scicluna; Evangelos J. Giamarellos-Bourboulis; Antigone Kotsaki; Ignacio Martin-Loeches; Alexis Garduno; Richard E. Rothman; Jonathan Sevransky; David W. Wright; Mihir R. Atreya; Lyle L. Moldawer; Philip A. Efron; Marcela Kralovcova; Thomas Karvunidis; Heather M. Giannini; Nuala J. Meyer; Timothy E. Sweeney; Angela J. Rogers; Purvesh Khatri
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Clinical validation of an AI-based blood testing device for diagnosis and prognosis of acute infection and sepsis
errNature Medicine
IF50
err2025-09-30
err0
errOAAI
errOliver Liesenfeld; Sanjay Arora; Tom P. Aufderheide; Casey M. Clements; Elizabeth DeVos; Miriam Fischer; Evangelos J. Giamarellos-Bourboulis; Stacey House; Roger L. Humphries; Jasreen Kaur Gill; Edward Liu; Sharon E. Mace; Larissa May; Edward Michelson; Tiffany M. Osborn; Edward Panacek; Richard E. Rothman; Wesley H. Self; Howard A. Smithline; Jay Steingrub; Paul Van Heukelom; Alexandra Weissman; Matthew Wilson; Donna M. Wolk; David W. Wright; Ljubomir Buturovic; Yehudit Hasin-Brumshtein; Nandita Damaraju; Cici Lu; Joshua R. Shak; Natalie N. Whitfield; Purvesh Khatri; Timothy E. Sweeney; Nathan I. Shapiro
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A consensus blood transcriptomic framework for sepsis
errNature Medicine
IF50
err2025-09-30
err0
errOAAI
errBrendon P. Scicluna; Kiki Cano-Gamez; Katie L. Burnham; Emma E. Davenport; Andrew Reese Moore; Soumen Khan; Charles J. Hinds; Olaf L. Cremer; Purvesh Khatri; Timothy E. Sweeney; Julian C. Knight; Tom van der Poll
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29-mRNA host response signatures for classification of bacterial infection, viral infection and disease progression in COVID-19 pneumonia: a post hoc analysis of the SAVE-MORE randomized clinical trial
errIntensive Care Medicine Experimental
IF3.1
err2025-06-30
err0
errOAAI
errEvdoxia Kyriazopoulou; Antigone Kotsaki; Asimina Safarika; Garyfallia Poulakou; Haralampos Milionis; Simeon Metallidis; Georgios Adamis; Archontoula Fragkou; Aggeliki Rapti; Pierluigi Del Vecchio; Ioannis Kalomenidis; Danae Kitzoglou; Andrea Angheben; Ilias Kainis; Konstantina Iliopoulou; Francesco Saverio Serino; Petros Bakakos; Vassiliki Tzavara; Sofia Ioannou; Lorenzo Dagna; Katerina Dimakou; Glykeria Tzatzagou; Maria Chini; Matteo Bassetti; Vasileios Kotsis; George Tsoukalas; Carlo Selmi; Sofia Nikolakopoulou; Michael Samarkos; Michael Doumas; Aikaterini Masgala; Ilias Papanikolaou; Aikaterini Argyraki; Karolina Akinosoglou; Styliani Symbardi; Periklis Panagopoulos; George N. Dalekos; Oliver Liesenfeld; Timothy E. Sweeney; Purvesh Khatri; Evangelos J. Giamarellos-Bourboulis
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Pathogen-specific host response in critically ill patients with blood stream infections: a nested case–control study
erreBioMedicine
IF10.8
err2025-06-11
err0
PREAI
errJoe M. Butler; Hessel Peters-Sengers; Tom D.Y. Reijnders; Tjitske S.R. van Engelen; Fabrice Uhel; Lonneke A. van Vught; Marcus J. Schultz; Pierre-François Laterre; Bruno François; Miguel Sánchez-García; Eleuterio Lombardo; Timothy E. Sweeney; Marc J. Bonten; W. Joost Wiersinga; Dayle Sampson; Leo C. Bolero; Thomas Yager; Olaf L. Cremer; Brendon P. Scicluna; Tom van der Poll
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Early sepsis recognition: a pilot study using a rapid high-multiplex host-response mRNA diagnostic test
errINTENSIVE CARE MEDICINE EXPERIMENTAL
IF3.1
err2025-02-21
err1
errOAAI
errLu, Jingyi; ter Voert, Michele A.; Unal, Mehtap; Whitfield, Natalie N.; Liesenfeld, Oliver; ter Maaten, Jan C.; Sweeney, Timothy E.; Bouma, Hjalmar R.
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Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes
errCRITICAL CARE
IF9.3
err2024-07-17
err0
errOAAI
errAtreya, Mihir R.; Huang, Min; Moore, Andrew R.; Zheng, Hong; Hasin-Brumshtein, Yehudit; Fitzgerald, Julie C.; Weiss, Scott L.; Cvijanovich, Natalie Z.; Bigham, Michael T.; Jain, Parag N.; Schwarz, Adam J.; Lutfi, Riad; Nowak, Jeffrey; Thomas, Neal J.; Quasney, Michael; Dahmer, Mary K.; Baines, Torrey; Haileselassie, Bereketeab; Lautz, Andrew J.; Stanski, Natalja L.; Standage, Stephen W.; Kaplan, Jennifer M.; Zingarelli, Basilia; Sahay, Rashmi; Zhang, Bin; Sweeney, Timothy E.; Khatri, Purvesh; Sanchez-Pinto, L. Nelson; Kamaleswaran, Rishikesan
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Monocyte state 1 (MS1) cells in critically ill patients with sepsis or non-infectious conditions: association with disease course and host response
errCRITICAL CARE
IF9.3
err2024-03-19
err4
errOAAI
errLeite, Giuseppe G. F.; de Brabander, Justin; Michels, Erik H. A.; Butler, Joe M.; Cremer, Olaf L.; Scicluna, Brendon P.; Sweeney, Timothy E.; Reyes, Miguel; Salomao, Reinaldo; Peters-Sengers, Hessel; van der Poll, Tom
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Transitions of blood immune endotypes and improved outcome by anakinra in COVID-19 pneumonia: an analysis of the SAVE-MORE randomized controlled trial
errCRITICAL CARE
IF9.3
err2024-03-12
err5
errOAAI
errKyriazopoulou, Evdoxia; Hasin-Brumshtein, Yehudit; Midic, Uros; Poulakou, Garyfallia; Milionis, Haralampos; Metallidis, Simeon; Astriti, Myrto; Fragkou, Archontoula; Rapti, Aggeliki; Taddei, Eleonora; Kalomenidis, Ioannis; Chrysos, Georgios; Angheben, Andrea; Kainis, Ilias; Alexiou, Zoi; Castelli, Francesco; Serino, Francesco Saverio; Bakakos, Petros; Nicastri, Emanuele; Tzavara, Vasiliki; Ioannou, Sofia; Dagna, Lorenzo; Dimakou, Katerina; Tzatzagou, Glykeria; Chini, Maria; Bassetti, Matteo; Kotsis, Vasileios; Tsoukalas, Dionysios G.; Selmi, Carlo; Konstantinou, Alexandra; Samarkos, Michael; Doumas, Michael; Masgala, Aikaterini; Pagkratis, Konstantinos; Argyraki, Aikaterini; Akinosoglou, Karolina; Symbardi, Styliani; Netea, Mihai G.; Panagopoulos, Periklis; Dalekos, George N.; Liesenfeld, Oliver; Sweeney, Timothy E.; Khatri, Purvesh; Giamarellos-Bourboulis, Evangelos J.
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Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study
errCRITICAL CARE
IF9.3
err2023-07-20
err10
errOAAI
errBalch, Jeremy A.; Chen, Uan-, I; Liesenfeld, Oliver; Starostik, Petr; Loftus, Tyler J.; Efron, Philip A.; Brakenridge, Scott C.; Sweeney, Timothy E.; Moldawer, Lyle L.
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A Spotlight on Disruptors and Innovators
errCLINICAL CHEMISTRY
IF6.3
err2023-02-15
err0
errOAAI
errPatel, Khushbu; Evans, Susan; Lee, Jong; Pamula, Vamsee; Shah, Ajay; Sweeney, Timothy E.; Tadimety, Amogha
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Multisite validation of a host response signature for predicting likelihood of bacterial and viral infections in patients with suspected influenza
errEUROPEAN JOURNAL OF CLINICAL INVESTIGATION
IF3.6
err2023-02-08
err3
errOAAI
errShojaei, Maryam; Chen, Uan-, I; Midic, Uros; Thair, Simone; Teoh, Sally; McLean, Anthony; Sweeney, Timothy E.; Thompson, Matthew; Liesenfeld, Oliver; Khatri, Purvesh; Tang, Benjamin
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A robust host-response-based signature distinguishes bacterial and viral infections across diverse global populations
errCELL REPORTS MEDICINE
IF10.6
err2022-12-01
err14
errOAAI
errRao, Aditya M.; Popper, Stephen J.; Gupta, Sanjana; Davong, Viengmon; Vaidya, Krista; Chanthongthip, Anisone; Dittrich, Sabine; Robinson, Matthew T.; Vongsouvath, Manivanh; Mayxay, Mayfong; Nawtaisong, Pruksa; Karmacharya, Biraj; Thair, Simone A.; Bogoch, Isaac; Sweeney, Timothy E.; Newton, Paul N.; Andrews, Jason R.; Relman, David A.; Khatri, Purvesh
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A new possibility: gene-expression-based diagnostics for presymptomatic diagnosis of hospital-acquired infections
errINTENSIVE CARE MEDICINE
IF21.2
err2022-08-02
err0
errOAAI
errMoita, Luis F.; Sweeney, Timothy E.; Povoa, Pedro
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errSave
Redefining critical illness
errNATURE MEDICINE
IF50
err2022-06-17
err170
errOAAI
errMaslove, David M.; Tang, Benjamin; Shankar-Hari, Manu; Lawler, Patrick R.; Angus, Derek C.; Baillie, J. Kenneth; Baron, Rebecca M.; Bauer, Michael; Buchman, Timothy G.; Calfee, Carolyn S.; dos Santos, Claudia C.; Giamarellos-Bourboulis, Evangelos J.; Gordon, Anthony C.; Kellum, John A.; Knight, Julian C.; Leligdowicz, Aleksandra; McAuley, Daniel F.; McLean, Anthony S.; Menon, David K.; Meyer, Nuala J.; Moldawer, Lyle L.; Reddy, Kiran; Reilly, John P.; Russell, James A.; Sevransky, Jonathan E.; Seymour, Christopher W.; Shapiro, Nathan I.; Singer, Mervyn; Summers, Charlotte; Sweeney, Timothy E.; Thompson, B. Taylor; van der Poll, Tom; Venkatesh, Balasubramanian; Walley, Keith R.; Walsh, Timothy S.; Ware, Lorraine B.; Wong, Hector R.; Zador, Zsolt E.; Marshall, John C.
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Prospective validation of a transcriptomic severity classifier among patients with suspected acute infection and sepsis in the emergency department
errEUROPEAN JOURNAL OF EMERGENCY MEDICINE
IF4.2
err2022-04-21
err20
errOAAI
errGaltung, Noa; Diehl-Wiesenecker, Eva; Lehmann, Dana; Markmann, Natallia; Bergstrom, Wilma H.; Wacker, James; Liesenfeld, Oliver; Mayhew, Michael; Buturovic, Ljubomir; Luethy, Roland; Sweeney, Timothy E.; Tauber, Rudolf; Kappert, Kai; Somasundaram, Rajan; Bauer, Wolfgang
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Research Directions

No research directions
Co-authors
Cooperation Journals
J
John P. A. Ioannidis
H-index: 226 · Papers: 1.9K
M
Mihai G. Netea
H-index: 183 · Papers: 1.7K
J
John A. Kellum
H-index: 153 · Papers: 2.5K
B
Bruce Thompson
H-index: 142 · Papers: 2.0K
D
Derek C. Angus
H-index: 141 · Papers: 799
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