Manuel Tena‐Sempere - Publications, H-index & Citations

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Manuel Tena‐Sempere

hospital universitario reina sofia

101H-index

531Paper Count

3.2WCitation Count

Published Papers 280

Publication Date

A new era in childhood obesity

trends in endocrinology & metabolism

IF0

2026-04-01

OAAI

Gabriel Á. Martos-Moreno; Blanca Guijo; Manuel Tena-Sempere; Julie A. Chowen; Jesús Argente

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Microglia Rank signaling regulates GnRH neuronal function and the hypothalamic-pituitary-gonadal axis

Science

IF45.8

2026-03-12

PREAI

Alejandro Collado-Sole; Nozha Borjini; Jing Zhai; Francisco Ruiz-Pino; Gonzalo Soria-Alcaide; Cintia Folgueira; Celia García-Vilela; Beatriz Romero-de la Rosa; Victor Lopez; Yassine Zouaghi; An Jacobs; Bella Mora-Romero; Alexandra Barranco; Guillermo Yoldi; Karine Rizzoti; Guadalupe Sabio; Gema Perez-Chacon; Patricia G. Santamaria; Jose Antonio Esteban; Nathalie Journiac; Vincent Prevot; Alberto Pascual; Rafael Fernández-Chacón; Manuel Tena-Sempere; Nelly Pitteloud; Eva Gonzalez-Suarez

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EndoCompass Project: Research Roadmap for Reproductive and Developmental Endocrinology

HORMONE RESEARCH IN PAEDIATRICS

IF2.7

2025-12-01

OAAI

Cools, Martine; Krausz, Csilla; Juul, Anders; Macut, Djuro; Andersen, Marianne Skovsager; Andersson, Anna-Maria; Andoniadou, Cynthia L.; Ahmed, S. Faisal; Bakker, Julie; Bashamboo, Anu; Behre, Hermann M.; Bonomi, Marco; Busch, Alexander Siegfried; De Roo, Chloe; Dessens, Arianne; Fakhar-I-Adil, Muhammad; Fanelli, Flaminia; Fisher, Alessandra Daphne; Fluck, Christa; Gambineri, Alessandra; Giwercman, Aleksander; Gravholt, Claus H.; Hannema, Sabine; Heindryckx, Bjorn; Hiort, Olaf; Hornig, Nadine C.; Howard, Sasha; Ibanez, Lourdes; Jensen, Martin Blomberg; Jorgensen, Niels; Livadas, Sarantis; Lucas-Herald, Angela; Mastorakos, George; Meriggiola, Maria Cristina; Ong, Ken; Palibrk, Milica Opalic; Pignatelli, Duarte; Pitteloud, Nelly; Rajpert-De Meyts, Ewa; Rey, Rodolfo; Robeva, Ralitsa; Pozza, Carlotta; Schlatt, Stefan; Spaggiari, Giorgia; Tack, Lloyd; Tena-Sempere, Manuel; Tournaye, Herman; T'sjoen, Guy; Van Mello, Norah; Vena, Walter; Yildiz, Bulent O.; De Zegher, Francis

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OBEClust: joining forces to prevent obesity

Nature Reviews Endocrinology

IF31.8

2025-11-11

PREAI

Manuel Tena-Sempere; Dimitrios-Dionyssios Koutsouris; George Dedoussis; Jeroen Lakerveld; Karl-Heinz Wagner; Itziar Tueros; Philippe Froguel; Torsten Bohn; Paulo J. Oliveira

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Hypothalamic control of puberty: from neuronal circuits to mechanisms for its metabolic regulation

Reviews in Endocrine and Metabolic Disorders

IF8

2025-10-18

OAAI

Manuel Jimenez-Puyer; Verónica Sobrino; William H. Colledge; Susan Jones; Manuel Tena-Sempere

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EndoCompass project: research roadmap for reproductive and developmental endocrinology

EUROPEAN JOURNAL OF ENDOCRINOLOGY

IF5.2

2025-10-01

OAAI

Cools, Martine; Krausz, Csilla; Juul, Anders; Macut, Djuro; Andersen, Marianne Skovsager; Andersson, Anna-Maria; Andoniadou, Cynthia L.; Ahmed, S. Faisal; Bakker, Julie; Bashamboo, Anu; Behre, Hermann M.; Bonomi, Marco; Busch, Alexander Siegfried; De Roo, Chloe; Dessens, Arianne; Fakhar-I-Adil, Muhammad; Fanelli, Flaminia; Fisher, Alessandra Daphne; Fluck, Christa; Gambineri, Alessandra; Giwercman, Aleksander; Gravholt, Claus H.; Hannema, Sabine; Heindryckx, Bjorn; Hiort, Olaf; Hornig, Nadine C.; Howard, Sasha; Ibanez, Lourdes; Blomberg Jensen, Martin; Jorgensen, Niels; Livadas, Sarantis; Lucas-Herald, Angela; Mastorakos, George; Meriggiola, Maria Cristina; Ong, Ken; Opalic Palibrk, Milica; Pignatelli, Duarte; Pitteloud, Nelly; Rajpert-De Meyts, Ewa; Rey, Rodolfo; Robeva, Ralitsa; Pozza, Carlotta; Schlatt, Stefan; Spaggiari, Giorgia; Tack, Lloyd; Tena-Sempere, Manuel; Tournaye, Herman; T'Sjoen, Guy; Van Mello, Norah; Vena, Walter; Yildiz, Bulent O.; de Zegher, Francis

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Corrigendum to “IL-6 decodes sex and diet-dependent circadian and metabolic rhythms” [Mol Metabol 97 (2025) 102171]

Molecular Metabolism

IF6.6

2025-07-09

PREAI

Antía González-Vila; Ali Mohammad Ibrahim-Alasoufi; María Luengo-Mateos; Víctor Pardo-García; Alejandro Diaz-López; Belén Fernández-Rodríguez; Matti Poutanen; Claes Ohlsson; Manuel Tena-Sempere; Carlos Diéguez-González; María Del Carmen García-García; Olga Barca-Mayo

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Cannabidiol improves metabolic profiles and alleviates liver inflammation and fibrosis in conditions of androgenic obesity and polycystic ovary syndrome

diabetes obesity metabolism

IF0

2025-07-09

OAAI

Francisco J. Ponce-Díaz BSc; Francisco Ruiz-Pino PhD; Martín Garrido-Rodriguez PhD; María E. Prados-González PhD; Esperanza Uceda-Rodriguez BSc; Laura Cerero-Tejero BSc; Yolanda Guerrero-Ruiz BSc; Miguel A. Sanchez-Garrido PhD; Eduardo Muñoz MD; Manuel Tena-Sempere MD

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Corrigendum to “Influence of gender and menopausal status on gut microbiota” [Maturitas Vol. 116 (2018) 43-53]

Maturitas

IF3.6

2025-06-12

PREAI

Jose A. Santos-Marcos; Oriol A. Rangel-Zuñiga; Rosa Jimenez-Lucena; Gracia M. Quintana-Navarro; Sonia Garcia-Carpintero; Maria M. Malagon; Blanca B. Landa; Manuel Tena-Sempere; Pablo Perez-Martinez; Jose Lopez-Miranda; Francisco Perez-Jimenez; Antonio Camargo

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Central lipid sensing pathways contribute to the control of puberty and its alterations in conditions of obesity

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

IF3.1

2025-05-01

PREAI

Rodríguez-Vázquez, E; Aranda-Torrecillas, A; López-Sancho, M; Jiménez-Puyer, M; Daza-Dueñas, S; Barroso, A; Sobrino, V; Gaytan, F; Obis, E; Castellano, JM; Tena-Sempere, M

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Hypothalamic SIRT1-mediated regulation of the hormonal trigger of ovulation and its repression in energy deficit

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2025-03-01

OAAI

Vazquez, Maria J.; Daza-Duenas, Silvia; Velasco, Inmaculada; Ruiz-Pino, Francisco; Sanchez-Tapia, Maria J.; Manfredi-Lozano, Maria; Torres-Granados, Carmen; Barroso, Alexia; Roa, Juan; Sanchez-Garrido, Miguel A.; Dieguez, Carlos; Lomniczi, Alejandro; Nogueiras, Ruben; Tena-Sempere, Manuel

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SF1-specific deletion of the energy sensor AMPKg2 induces obesity

MOLECULAR METABOLISM

IF6.6

2025-02-01

OAAI

Freire-Agulleiro, Oscar; Estevez-Salguero, Anxela; Ferreira, Vitor; Holleman, Cassie Lynn; Garcia-Curras, Julia; Gonzalez-Garcia, Ismael; Nogueiras, Ruben; Tena-Sempere, Manuel; Garcia-Caceres, Cristina; Dieguez, Carlos; Lopez, Miguel

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Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy

NATURE COMMUNICATIONS

IF15.7

2024-10-01

OAAI

Sanchez-Garrido, Miguel A.; Serrano-Lopez, Victor; Ruiz-Pino, Francisco; Vazquez, Maria Jesus; Rodriguez-Martin, Andrea; Torres, Encarnacion; Velasco, Inmaculada; Rodriguez, Ana Belen; Chicano-Galvez, Eduardo; Mora-Ortiz, Marina; Ohlsson, Claes; Poutanen, Matti; Pinilla, Leonor; Gaytan, Francisco; Douros, Jonathan D.; Yang, Bin; Mueller, Timo D.; Dimarchi, Richard D.; Tschoep, Matthias H.; Finan, Brian; Tena-Sempere, Manuel

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Emerging roles of lipid and metabolic sensing in the neuroendocrine control of body weight and reproduction

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2024-09-03

OAAI

Rodriguez-Vazquez, Elvira; Aranda-Torrecillas, Alvaro; Lopez-Sancho, Maria; Castellano, Juan M.; Tena-Sempere, Manuel

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The evolutionary conserved miR-137/325 tandem mediates obesity-induced hypogonadism and metabolic comorbidities by repressing hypothalamic kisspeptin

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2024-08-01

OAAI

Avendano, Maria S.; Perdices-Lopez, Cecilia; Guerrero-Ruiz, Yolanda; Ruiz-Pino, Francisco; Rodriguez-Sanchez, Ana B.; Sanchez-Tapia, Maria J.; Sobrino, Veronica; Pineda, Rafael; Barroso, Alexia; Correa-Saez, Alejandro; Lara-Chica, Maribel; Fernandez-Garcia, Jose C.; Garcia-Redondo, Ana B.; Hernanz, Raquel; Ruiz-Cruz, Miguel; Garcia-Galiano, David; Pitteloud, Nelly; Calzado, Marco A.; Briones, Ana M.; Vazquez, Maria J.; Tena-Sempere, Manuel

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Kisspeptins centrally modulate food intake and locomotor activity in mice independently of gonadal steroids in a sexually dimorphic manner

JOURNAL OF NEUROENDOCRINOLOGY

IF4.1

2024-07-23

OAAI

Velasco, Inmaculada; Daza-Duenas, Silvia; Torres, Encarnacion; Ruiz-Pino, Francisco; Vazquez, Maria J.; Tena-Sempere, Manuel

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Kisspeptin signaling in astrocytes modulates the reproductive axis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-06-11

OAAI

Torres, Encarnacion; Pellegrino, Giuliana; Granados-Rodriguez, Melissa; Fuentes-Fayos, Antonio C.; Velasco, Inmaculada; Coutteau-Robles, Adrian; Legrand, Amandine; Shanabrough, Marya; Perdices-Lopez, Cecilia; Leon, Silvia; Yeo, Shel H.; Manchishi, Stephen M.; Sanchez-Tapia, Maria J.; Navarro, Victor M.; Pineda, Rafael; Roa, Juan; Naftolin, Frederick; Argente, Jesus; Luque, Raul M.; Chowen, Julie A.; Horvath, Tamas L.; Prevot, Vincent; Sharif, Ariane; Colledge, William H.; Tena-Sempere, Manuel; Romero-Ruiz, Antonio

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Eating disorders and obesity: bridging clinical , neurobiological, and therapeutic perspectives

Trends in Molecular Medicine

IF13.8

2024-04-01

OAAI

Camacho-Barcia, Lucia; Giel, Katrin Elisabeth; Jimenez-Murcia, Susana; Pitti, Julio Alvarez; Micali, Nadia; Lucas, Ignacio; Miranda-Olivos, Romina; Munguia, Lucero; Tena-Sempere, Manuel; Zipfel, Stephan; Fernandez-Aranda, Fernando

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Metabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra's seminal work

nature reviews endocrinology

IF40

2023-12-04

OAAI

Anderson, Greg M.; Hill, Jennifer W.; Kaiser, Ursula B.; Navarro, Victor M.; Ong, Ken K.; Perry, John R. B.; Prevot, Vincent; Tena-Sempere, Manuel; Elias, Carol F.

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PFAS association with kisspeptin and sex hormones in teenagers of the HBM4EU aligned studies

ENVIRONMENTAL POLLUTION

IF7.3

2023-10-01

PREAI

Rodriguez-Carrillo, Andrea; Remy, Sylvie; Koppen, Gudrun; Wauters, Natasha; Freire, Carmen; Olivas-Martinez, Alicia; Schillemans, Tessa; Akesson, Agneta; Desalegn, Anteneh; Iszatt, Nina; den Hond, Elly; Verheyen, Veerle; Fabelova, Lucia; Murinova, Lubica Palkovicova; Pedraza-Diaz, Susana; Castana, Argelia; Garcia-Lario, Jose Vicente; Cox, Bianca; Govarts, Eva; Baken, Kirsten; Tena-Sempere, Manuel; Olea, Nicolas; Schoeters, Greet; Fernandez, Mariana F.

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Research Directions