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J

Joshua D. Wythe

university of virginia

29H-index
89Paper Count
5.9KCitation Count
Published Papers 41
Publication Date
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ERG preserves endothelial identity to limit atherosclerosis
errNature Communications
IF15.7
err2026-07-13
err0
errOAAI
errSteven R. Botts; Corey A. Scipione; Kristen Schulz; Leandro C. D. Breda; Kai Ellis; Christy Ho; Sneha Raju; Kamalben Prajapati; Kai Yu; Aniqa B. Khan; Chanele K. Polenz; Stylianos Z. Prattas; Sharon J. Hyduk; Christian Cao; Joshua D. Wythe; Clint S. Robbins; Clint L. Miller; Myron I. Cybulsky; Jason E. Fish; Kathryn L. Howe
errShare
errSave
Comparative analysis of clearing methods for 3D imaging of the vasculature in mineralized mouse tissues
erriScience
IF4.1
err2026-03-25
err0
errOAAI
errAzeez O. Ishola; Athira Pillai; Taeyong Ahn; Chih-Wei Hsu; Brendan Lee; Nele Haelterman; Joshua D. Wythe
errShare
errSave
MultiSite Assembly of Gateway Induced Clones (MAGIC) : a flexible cloning toolbox for use in vertebrate model systems
errDEVELOPMENT
IF3.6
err2025-11-01
err0
PREAI
errGillespie, William B.; Zhang, Yuwen; Ruiz, Oscar E.; Cerda, Juan; Ortiz-Guzman, Joshua; Sherman, Michelle; Turner, Williamson D.; Largoza, Gabrielle; Mosser, Lili E.; Fujimoto, Esther; Chien, Chi-Bin; Kwan, Kristen M.; Arenkiel, Benjamin R.; Devine, W. Patrick; Wythe, Joshua D.
errShare
errSave
Segmentation and modeling of large-scale microvascular networks: a survey
errFrontiers in Bioinformatics
IF3.9
err2025-10-31
err0
errOAAI
errHelya Goharbavang; Artem T. Ashitkov; Athira Pillai; Joshua D. Wythe; Guoning Chen; David Mayerich
errShare
errSave
Computational Fluid Dynamic Model Prediction of Enhanced Glymphatic Clearance in Response to Focused Ultrasound-Mediated Blood-Brain Barrier Opening
errAdvanced Science
IF14.1
err2025-09-04
err0
errOAAI
errRyan A. Gladwell; Delaney G. Fisher; Joshua D. Wythe; Christopher B. Highley; John R. Lukens; Richard J. Price
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errSave
From bench to bedside: murine models of inherited and sporadic brain arteriovenous malformations
errANGIOGENESIS
IF9.2
err2025-02-03
err0
errOAAI
errRicciardelli, Ashely R.; Genet, Gael; Genet, Nafiisha; Mcclugage, Samuel T.; Kan, Peter T.; Hirschi, Karen K.; Fish, Jason E.; Wythe, Joshua D.
errShare
errSave
Loss Of The ETS Transcription Factor ERG Disrupts Fate-defining Programs In The Aortic Endothelium And Promotes Expansion Of Endothelial Lineage Cells In Atherosclerotic Plaque
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2024-05-01
err0
PREAI
errBotts, Steven R.; Schulz, Kristen; Scipione, Corey A.; Raju, Sneha; Breda, Leandro C.; Prajapati, Kamalben; Yu, Kai; Khan, Aniqa; Polenz, Chanele K.; Hyduk, Sharon J.; Wythe, Joshua D.; Robbins, Clint S.; Cybulsky, Myron I.; Fish, Jason E.; Howe, Kathryn L.
errShare
errSave
Endothelial cells adopt a pro-reparative immune responsive signature during cardiac injury
errLIFE SCIENCE ALLIANCE
IF2.9
err2023-11-27
err3
errOAAI
errLong, Hali; Steimle, Jeffrey; Canozo, Francisco Jose Grisanti; Kim, Jong Hwan; Li, Xiao; Morikawa, Yuka; Park, Minjun; Turaga, Diwakar; Adachi, Iki; Wythe, Joshua; Samee, Md Abul Hassan; Martin, James F.
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errSave
The Role and Therapeutic Implications of Inflammation in the Pathogenesis of Brain Arteriovenous Malformations
errBIOMEDICINES
IF3.9
err2023-10-24
err10
errOAAI
errRicciardelli, Ashley R.; Robledo, Ariadna; Fish, Jason E.; Kan, Peter T.; Harris, Tajie H.; Wythe, Joshua D.
errShare
errSave
Ifi27l2a Is A Novel Regulator Of Neuroinflammation And Neurodegeneration In The Post-stroke Brain
errSTROKE
IF8.9
err2023-02-01
err0
PREAI
errKim, Gab Seok; Harmon, Elisabeth; Doan, Andrea; Andersohn, Alexander; Wu, Ting; Gutierrez, Manuel C.; Wythe, Joshua D.; Marrelli, Sean P.
errShare
errSave
EZ Clear for simple, rapid, and robust mouse whole organ clearing
errELIFE
IF0
err2022-10-11
err30
errOAAI
errHsu, Chih-Wei; Cerda, Juan; Kirk, Jason M.; Turner, Williamson D.; Rasmussen, Tara L.; Suarez, Carlos P. Flores; Dickinson, Mary E.; Wythe, Joshua D.
errShare
errSave
A human model of arteriovenous malformation (AVM)-on-a-chip reproduces key disease hallmarks and enables drug testing in perfused human vessel networks
errBIOMATERIALS
IF12.9
err2022-09-01
err13
errOAAI
errSoon, Kayla; Li, Mengyuan; Wu, Ruilin; Zhou, Angela; Khosraviani, Negar; Turner, Williamson D.; Wythe, Joshua D.; Fish, Jason E.; Nunes, Sara S.
errShare
errSave
Computational insights on coronary artery function
errcardiovascular research
IF10.8
err2022-08-12
err0
errOAAI
errMayerich, David; Wythe, Joshua D.
errShare
errSave
FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac
errDEVELOPMENT
IF3.6
err2022-04-01
err5
errOAAI
errLi-Villarreal, Nanbing; Wong, Rebecca Lee Yean; Garcia, Monica D.; Udan, Ryan S.; Poche, Ross A.; Rasmussen, Tara L.; Rhyner, Alexander M.; Wythe, Joshua D.; Dickinson, Mary E.
errShare
errSave
RBFOX2 is required for establishing RNA regulatory networks essential for heart development
errNUCLEIC ACIDS RESEARCH
IF13.1
err2022-02-07
err25
errOAAI
errVerma, Sunil K.; Deshmukh, Vaibhav; Thatcher, Kaitlyn; Belanger, KarryAnne K.; Rhyner, Alexander M.; Meng, Shu; Holcomb, Richard Joshua; Bressan, Michael; Martin, James F.; Cooke, John P.; Wythe, Joshua D.; Widen, Steven G.; Lincoln, Joy; Kuyumcu-Martinez, Muge N.
errShare
errSave
Two Novel Interferon Signaling Proteins (Ifi27l2a And Ifitm3) Regulate Microglial Inflammation With Brain Aging And Following Stroke.
errSTROKE
IF8.9
err2022-02-01
err0
PREAI
errKim, Gab Seok; Wu, Ting; Andersohn, Alexander; Harmon, Elisabeth; Doan, Andrea; Gutierrez, Manuel E. Cantu; Wythe, Joshua D.; Marrelli, Sean P.
errShare
errSave
Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease
errcardiovascular research
IF10.8
err2021-12-23
err43
errOAAI
errRohde, David; Vandoorne, Katrien; Lee, I-Hsiu; Grune, Jana; Zhang, Shuang; McAlpine, Cameron S.; Schloss, Maximilian J.; Nayar, Ribhu; Courties, Gabriel; Frodermann, Vanessa; Wojtkiewicz, Gregory; Honold, Lisa; Chen, Qi; Schmidt, Stephen; Iwamoto, Yoshiko; Sun, Yuan; Cremer, Sebastian; Hoyer, Friedrich F.; Iborra-Egea, Oriol; Munoz-Guijosa, Christian; Ji, Fei; Zhou, Bin; Adams, Ralf H.; Wythe, Joshua D.; Hidalgo, Juan; Watanabe, Hideto; Jung, Yookyung; van der Laan, Anja M.; Piek, Jan J.; Kfoury, Youmna; Desogere, Pauline A.; Vinegoni, Claudio; Dutta, Partha; Sadreyev, Ruslan I.; Caravan, Peter; Bayes-Genis, Antoni; Libby, Peter; Scadden, David T.; Lin, Charles P.; Naxerova, Kamila; Swirski, Filip K.; Nahrendorf, Matthias
errShare
errSave
Single-Cell RNA Sequencing Identifies Ifi27l2a as a Novel Gene Involved in Regulating Microglial Inflammation in the Context of Aging and Stroke.
errSTROKE
IF8.9
err2021-03-01
err0
PREAI
errKim, Gab Seok; Stephenson, Jessica; Wu Ting; Gutierrez, Cantu Manuel E.; Wythe, Joshua D.; Marrelli, Sean P.
errShare
errSave
Identification of diverse tumor endothelial cell populations in malignant glioma
errNEURO-ONCOLOGY
IF13.4
err2020-12-23
err36
errOAAI
errCarlson, Jeff C.; Gutierrez, Manuel Cantu; Lozzi, Brittney; Huang-Hobbs, Emmet; Turner, Williamson D.; Tepe, Burak; Zhang, Yiqun; Herman, Alexander M.; Rao, Ganesh; Creighton, Chad J.; Wythe, Joshua D.; Deneen, Benjamin
errShare
errSave
Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling
errCIRCULATION RESEARCH
IF16.2
err2020-08-28
err82
errOAAI
errFish, Jason E.; Flores-Suarez, Carlos Perfecto; Boudreau, Emilie; Herman, Alexander M.; Gutierrez, Manuel Cantu; Gustafson, Dakota; DiStefano, Peter, V; Cui, Meng; Chen, Zhiqi; De Ruiz, Karen Berman; Schexnayder, Taylor S.; Ward, Christopher S.; Radovanovic, Ivan; Wythe, Joshua D.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Eric N. Olson
H-index: 224 · Papers: 979
王
王军 (Jun Wang)
H-index: 222 · Papers: 3.2K
S
Stylianos E. Antonarakis
H-index: 146 · Papers: 918
J
James R. Lupski
H-index: 144 · Papers: 1.1K
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