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David A. Wink

national institutes of health

112H-index
606Paper Count
4.4WCitation Count
Published Papers 231
Publication Date
Nitric Oxide-Driven Warburg Reprogramming at the NOS2-COX2 Axis: An Integrative Engine of Cancer Hallmarks.
err2026-06-02
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errLeandro L. Coutinho; Erika M. Palmieri; Lisa A. Ridnour; Robert Y.S. Cheng; Will F. Heinz; Stephen K. Anderson; Timothy R. Billiar; Jenny Chang; Stephen J. Lockett; M. Cristina Rangel; Douglas D. Thomas; Daniel W. McVicar; David A. Wink
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NOS2 and COX2 impact the spatial landscape of CD8+ T cells in ER- breast cancer, providing novel mechanistic insight that drives tumor progression and poor survival
err2026-04-27
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errLisa A. Ridnour; Robert Y.S. Cheng; William F. Heinz; Leandro L. Coutinho; Erika M. Palmieri; M.Cristina Rangel; Stephen K. Anderson; Daniel W. McVicar; Stephen M. Hewitt; Stephen T.C. Wong; Xiaoxian Li; Stefan Ambs; Timothy R. Billiar; Sharon A. Glynn; Jenny C. Chang; Stephen J. Lockett; David A. Wink
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SPAC: a scalable and integrated enterprise platform for single-cell spatial analysis
err2026-01-29
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errFang Liu; Rui He; Thomas Sheeley; David A. Scheiblin; Stephen J. Lockett; Lisa A. Ridnour; David A. Wink; Mark Jensen; Janelle Cortner; George Zaki
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TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells
err2025-06-01
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PREAI
errKundu, Manjari; Greer, Yoshimi E.; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N.; Ng, Yeap; Ratnayake, Shashi; White, Karley; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett, Stephen J.; Cam, Maggie; Meerzaman, Daoud; Wink, David A.; Weigert, Roberto; Lipkowitz, Stanley
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Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors
err2024-05-21
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errRidnour, Lisa A.; Cheng, Robert Y. S.; Kedei, Noemi; Somasundaram, Veena; Bhattacharyya, Dibyangana D.; Basudhar, Debashree; Wink, Adelaide L.; Walke, Abigail J.; Kim, Caleb; Heinz, William F.; Edmondson, Elijah F.; Butcher, Donna O.; Warner, Andrew C.; Dorsey, Tiffany H.; Pore, Milind; Kinders, Robert J.; Lipkowitz, Stanley; Bryant, Richard J.; Rittscher, Jens; Wong, Stephen T. C.; Hewitt, Stephen M.; Chang, Jenny C.; Shalaby, Aliaa; Callagy, Grace M.; Glynn, Sharon A.; Ambs, Stefan; Anderson, Stephen K.; McVicar, Daniel W.; Lockett, Stephen J.; Wink, David A.
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Tumor necrosis factor related apoptosis inducing ligand (TRAIL)-induced cytokine production in TNBC promotes neutrophil chemotaxis and immune suppression
err2024-03-22
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PREAI
errKundu, Manjari; Greer, Yoshimi Endo; Ridnour, Lisa Ann; Wink, David A.; Ng, Yeap S.; Weigert, Roberto; Lipkowitz, Stan
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Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming
err2023-08-22
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errPalmieri, Erika M.; Holewinski, Ronald; McGinity, Christopher L.; Pierri, Ciro L.; Maio, Nunziata; Weiss, Jonathan M.; Tragni, Vincenzo; Miranda, Katrina M.; Rouault, Tracey A.; Andresson, Thorkell; Wink, David A.; McVicar, Daniel W.
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Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome
err2023-05-11
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errCheng, Robert Y. S.; Ridnour, Lisa A.; Wink, Adelaide L.; Gonzalez, Ana L.; Femino, Elise L.; Rittscher, Helene; Somasundaram, Veena; Heinz, William F.; Coutinho, Leandro; Rangel, M. Cristina; Edmondson, Elijah F.; Butcher, Donna; Kinders, Robert J.; Li, Xiaoxian; Wong, Stephen T. C.; McVicar, Daniel W.; Anderson, Stephen K.; Pore, Milind; Hewitt, Stephen M.; Billiar, Timothy R.; Glynn, Sharon A.; Chang, Jenny C.; Lockett, Stephen J.; Ambs, Stefan; Wink, David A.
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Pyruvate Dehydrogenase Operates as an Intramolecular Nitroxyl Generator During Macrophage Metabolic Reprogramming
err2023-05-01
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errPalmieri, Erika M.; Holewinski, Ronald; McGinity, Christopher; Pierri, Ciro; Maio, Nunziata; Wink, David; McVicar, Daniel W.
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IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium
err2023-04-20
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errAndrews, Caroline; McLean, Mairi H.; Hixon, Julie A.; Pontejo, Sergio M.; Starr, Tregei; Malo, Courtney; Cam, Margaret; Ridnour, Lisa; Hickman, Heather; Steele-Mortimer, Olivia; Wink, David A.; Young, Howard A.; McVicar, Daniel W.; Li, Wenqing; Durum, Scott K.
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Interferon-gamma induces NOS2 and COX2 in ER-breast cancer that drives increase metastatic potential
err2023-04-04
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PREAI
errCheng, Yuk Sing Robert; Ridnour, Lisa; Walke, Abigail; Kedei, Noemi; Wink, Adelaide; Edmonston, Elijah; Butcher, Donna; Dorsey, Tiffany; Heinz, William; Bryant, Richard; Kinders, Robert; Lipkowitz, Stanley; Wong, Stephen; Pore, Milind; Hewitt, Stephen; McVicar, Daniel; Anderson, Stephen; Chang, Jenny; Ambs, Stefan; Lockett, Stephen; Wink, David
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Multiplex proteomics profiling with the imaging mass cytometry (IMC) identifies immune cell phenotypes associated with high NOS2/COX2 expression in ER- negative and TNBC patients
err2023-04-04
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PREAI
errPore, Milind; Ridnour, Lisa; Mallory, Paul; Cardamone, Ashley; Lockett, Stephen; Bocik, William; Wink, David
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New nitrosyl ruthenium complexes with combined activities for multiple cardiovascular disorders
err2023-01-01
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errGouveia Junior, Florencio Sousa; Silveira, Joao Alison de Moraes; Holanda, Thais Muratori; Marinho, Aline Diogo; Ridnour, Lisa A.; Wink, David A.; de Siqueira, Rodrigo Jose Bezerra; Monteiro, Helena Serra Azul; de Sousa, Eduardo Henrique Silva; Lopes, Luiz Gonzaga de Franca
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Targeting Nitric Oxide: Say NO to Metastasis
err2022-12-15
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errReddy, Tejaswini P.; Glynn, Sharon A.; Billiar, Timothy R.; Wink, David A.; Chang, Jenny C.
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Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density
err2022-12-01
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errSomasundaram, Veena; Ridnour, Lisa A.; Cheng, Robert Ys; Walke, Abigail J.; Kedei, Noemi; Bhattacharyya, Dibyangana D.; Wink, Adelaide L.; Edmondson, Elijah F.; Butcher, Donna; Warner, Andrew C.; Dorsey, Tiffany H.; Scheiblin, David A.; Heinz, William; Bryant, Richard J.; Kinders, Robert J.; Lipkowitz, Stanley; Wong, Stephen T. C.; Pore, Milind; Hewitt, Stephen M.; McVicar, Daniel W.; Anderson, Stephen K.; Chang, Jenny; Glynn, Sharon A.; Ambs, Stefan; Lockett, Stephen J.; Wink, David A.
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HNO Protects the Myocardium against Reperfusion Injury, Inhibiting the mPTP Opening via PKCε Activation
err2022-02-14
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errMancardi, Daniele; Pagliaro, Pasquale; Ridnour, Lisa A.; Tocchetti, Carlo G.; Miranda, Katrina; Juhaszova, Magdalena; Sollott, Steven J.; Wink, David A.; Paolocci, Nazareno
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Nitric Oxide and Cancer: When to Give and When to Take Away?
err2021-10-25
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PREAI
errMiranda, Katrina M.; Ridnour, Lisa A.; McGinity, Christopher L.; Bhattacharyya, Dana; Wink, David A.
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