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The prevalence of ENPP1 deficiency in humans with Ossification of the Posterior Longitudinal Ligament and the preclinical efficacy of ENPP1 enzyme therapy in murine Ossification of the Posterior Longitudinal Ligament Srivastava, Shivani; Kato, Hajime; Von Kroge, Simon; Weise, Keith; Stabach, Paul; Lopez, Sam G.; O'brien, Kevin; Lester, Ethan R.; Kim, Hana; Ishaq, Tayyaba; Dammen-Brower, Kris; Schinke, Thorsten; Kimura, Soichiro; Miyahara, Junya; Doi, Toru; Oshima, Yasushi; Yarema, Kevin J.; Carpenter, Thomas O.; Sabbagh, Yves; Tommasini, Steven M.; Ito, Nobuaki; Oheim, Ralf; Braddock, Demetrios T. Share Save
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The effect of Rsk2 on TNFα-mediated bone loss in the TMJ and craniofacial skeleton Georgi, Gina Marie; Bachmann, Frederic; Luther, Julia; Derer, Anja; Heimel, Patrick; Tangl, Stefan; Kahl-Nieke, Baerbel; Leblanc, Aaron; Helms, Jill; Schett, Georg; Hirsch, Christian; Gruber, Reinhard; Amling, Michael; Schinke, Thorsten; Koehne, Till; Petersen, Julian Share Save
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Correction of osteopetrosis in the neonate oc/oc murine model after lentiviral vector gene therapy and non-genotoxic conditioning Penna, Sara; Zecchillo, Alessandra; Di Verniere, Martina; Fontana, Elena; Iannello, Valeria; Palagano, Eleonora; Mantero, Stefano; Cappelleri, Andrea; Rizzoli, Elena; Santi, Ludovica; Crisafulli, Laura; Filibian, Marta; Forlino, Antonella; Basso-Ricci, Luca; Scala, Serena; Scanziani, Eugenio; Schinke, Thorsten; Ficara, Francesca; Sobacchi, Cristina; Villa, Anna; Capo, Valentina Share Save
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HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis Schneegans, Svenja; Loeptien, Jana; Mojzisch, Angelika; Loreth, Desiree; Kretz, Oliver; Raschdorf, Christoph; Hanssen, Annkathrin; Gocke, Antonia; Siebels, Bente; Gunasekaran, Karthikeyan; Ding, Yi; Oliveira-Ferrer, Leticia; Brylka, Laura; Schinke, Thorsten; Schlueter, Hartmut; Paatero, Ilkka; Voss, Hannah; Werner, Stefan; Pantel, Klaus; Wikman, Harriet Share Save
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Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development Brylka, Laura J.; Alimy, Assil-Ramin; Tschaffon-Mueller, Miriam E. A.; Jiang, Shan; Ballhause, Tobias Malte; Baranowsky, Anke; von Kroge, Simon; Delsmann, Julian; Pawlus, Eva; Eghbalian, Kian; Pueschel, Klaus; Schoppa, Astrid; Haffner-Luntzer, Melanie; Beech, David J.; Beil, Frank Timo; Amling, Michael; Keller, Johannes; Ignatius, Anita; Yorgan, Timur A.; Rolvien, Tim; Schinke, Thorsten Share Save
An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling Hendrickx, Gretl; Boudin, Eveline; Mateiu, Ligia; Yorgan, Timur A.; Steenackers, Ellen; Kneissel, Michaela; Kramer, Ina; Mortier, Geert; Schinke, Thorsten; Van Hul, Wim Share Save
Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage Danyukova, Tatyana; Alimy, Assil-Ramin; Velho, Renata Voltolini; Yorgan, Timur A.; Di Lorenzo, Giorgia; von Kroge, Simon; Tidow, Henning; Wiegert, J. Simon; Hermans-Borgmeyer, Irm; Schinke, Thorsten; Rolvien, Tim; Pohl, Sandra Share Save
TMCO3, a Putative K+:Proton Antiporter at the Golgi Apparatus, Is Important for Longitudinal Growth in Mice and Humans Holling, Tess; Brylka, Laura; Scholz, Tasja; Bierhals, Tatjana; Herget, Theresia; Meinecke, Peter; Schinke, Thorsten; Oheim, Ralf; Kutsche, Kerstin Share Save
Fracture healing in a mouse model of Hajdu-Cheney-Syndrome with high turnover osteopenia results in decreased biomechanical stability Ballhause, Tobias Malte; Jiang, Shan; Xie, Weixin; Sevecke, Jan; Dowling, Christine; Dust, Tobias; Brandt, Sabine; Mertens, Peter R.; Yorgan, Timur Alexander; Schinke, Thorsten; Frosch, Karl-Heinz; Baranowsky, Anke; Keller, Johannes Share Save
Mechanical-induced bone remodeling does not depend on Piezo1 in dentoalveolar hard tissue Nottmeier, Cita; Lavicky, Josef; Gonzalez Lopez, Marcos; Knauth, Sarah; Kahl-Nieke, Baerbel; Amling, Michael; Schinke, Thorsten; Helms, Jill; Krivanek, Jan; Koehne, Till; Petersen, Julian Share Save
RAI2 is a novel bone metastasis-associated gene, mediating a vicious cross talk between breast cancer cells and osteoclasts Veiga, Thais Pereira; Werner, Stefan; Loreth, Desiree; Horn, Michael; Groninger, Melanie; Grabe, Moritz; Baranowsky, Anke; Taipaleenmaki, Hanna; Brylka, Laura; Kropidlowski, Jolanthe; Schinke, Thorsten; Pantel, Klaus; Wikman, Harriet Share Save
Wnt1 Boosts Fracture Healing by Enhancing Bone Formation in the Fracture Callus Haffner-Luntzer, Melanie; Ragipoglu, Deniz; Ahmad, Mubashir; Schoppa, Astrid; Steppe, Lena; Fischer, Verena; Luther, Julia; Yorgan, Timur; Bockamp, Ernesto; Amling, Michael; Schinke, Thorsten; Ignatius, Anita Share Save
Increased concentrations of conjugated bile acids are associated with osteoporosis in PSC patients Stuerznickel, Julian; Behler-Janbeck, Friederike; Baranowsky, Anke; Schmidt, Tobias; Schwinge, Dorothee; John, Clara; Lohse, Ansgar W.; Schramm, Christoph; Heeren, Joerg; Schinke, Thorsten; Amling, Michael Share Save