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J

Joseph Keane

Trinity College Dublin

51H-index
260Paper Count
1.7WCitation Count
Published Papers 92
Publication Date
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Human Macrophages Secrete Both Interferon α and Interferon β Proteins During Infection with Mycobacterium tuberculosis
errJournal of Interferon and Cytokine Research
IF1.8
err2026-08-01
err0
PREAI
errLeisching, Gina; Cox, Donal; Bondet, Vincent; Yennemadi, Anjali S.; Donohue, Sean; Duffy, Darragh; Keane, Joseph
errShare
errSave
Monocyte Metabolic Plasticity and Cytokine Production Differentiate Latent TB Infection from Active Disease
errJournal of Infection
IF11.9
err2026-04-26
err0
errOAAI
errGráinne Jameson; Isabella Batten; Adam H. Dyer; Caoimhe Geoghegan; Moninne Murray; Niamh McDonnell; Dearbhla M. Murphy; Sarah A. Connolly; Anne Marie McLaughlin; Cilian Ó Maoldomhnaigh; Laura E. Gleeson; Joseph Keane; Sharee A. Basdeo
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errSave
Whole genome sequencing confirms reactivation of tuberculosis five years after initial infection despite adequate preventative therapy in a patient with profound immunosuppression
errQJM-AN INTERNATIONAL JOURNAL OF MEDICINE
IF6.4
err2026-01-01
err0
errOAAI
errMcNally, Emma; O'Riordan, Sarahjane; Fitzgibbon, Margaret; Roycroft, Emma; Dolan, Lorraine; Flynn, Catherine; Keane, Joseph; McLaughlin, Annemarie
errShare
errSave
Sex-Specific Metabolic Programming in Human Neutrophil Subsets
errJournal of Leukocyte Biology
IF3.1
err2025-12-12
err0
errOAAI
errAnjali S Yennemadi; Faye K Murphy; Joseph Keane; Gina Leisching
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errSave
Genomic characterisation of recurrent Mycobacterium avium isolates from chronically infected patients reveals patterns of within-host evolution
errGenome Medicine
IF11.2
err2025-10-14
err0
errOAAI
errAaron M. Walsh; Emma Roycroft; Kate Hinchion; Sharee A. Basdeo; Frederick J. Sheedy; Fiona Crispie; Paul D. Cotter; Anne Marie McLaughlin; Joseph Keane; Margaret M. Fitzgibbon; Laura E. Gleeson
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errSave
The Emerging Role of Immunothrombosis in the Control and Pathogenesis of Mycobacterium tuberculosis
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2025-08-01
err0
errOAAI
errDonohue, Sean; Leisching, Gina; Keane, Joseph
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errSave
Mitochondrial bioenergetic failure in SLE immunocytes: Targeting fitness for therapy
errclinical immunology
IF3.8
err2025-07-21
err0
errOAAI
errAnjali S. Yennemadi; Natasha Jordan; Sophie Diong; Mark Little; Joseph Keane; Gina Leisching
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errSave
Human Alveolar Macrophages Detect SARS-CoV-2 Envelope Protein Through TLR2 and TLR4 and Secrete Cytokines in Response
errIMMUNOLOGY
IF5
err2025-05-04
err0
errOAAI
errConor Grant; Emily Duffin; Finbarr O’Connell; Parthiban Nadarajan; Colm Bergin; Joseph Keane; Mary P. O'Sullivan
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errSave
Delayed Tuberculosis Paradoxical Reaction Associated with Tumor Necrosis Factor Inhibitors
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2024-10-15
err0
PREAI
errRoche, Suzanne M.; Ottewill, Ciara; Mulpeter, Rachel; Brown, Kevin; Grant, Conor; Fraughen, Daniel D.; Dolan, Lorraine; Gleeson, Laura E.; Mclaughlin, Anne Marie; Keane, Joseph
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errSave
Microfluidics produced ATRA-loaded PLGA NPs reduced tuberculosis burden in alveolar epithelial cells and enabled high delivered dose under simulated human breathing pattern in 3D printed head models
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2024-05-01
err1
errOAAI
errBahlool, Ahmad Z.; Cavanagh, Brenton; O'Sullivan, Andrew; MacLoughlin, Ronan; Keane, Joseph; O'Sullivan, Mary P.; Cryan, Sally-Ann
errShare
errSave
The Link Between Dysregulated Immunometabolism and Vascular Damage: Implications for the Development of Atherosclerosis in Systemic Lupus Erythematosus and Other Rheumatic Diseases
errJOURNAL OF RHEUMATOLOGY
IF3.4
err2024-01-15
err5
errOAAI
errYennemadi, Anjali S.; Jordan, Natasha; Diong, Sophie; Keane, Joseph; Leisching, Gina
errShare
errSave
Dexamethasone Reduces Metabolic Function and Subsequent Activation of Human Macrophages to Mycobacterium Tuberculosis.
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2023-10-27
err0
PREAI
errThong, Lorraine; Cox, Donal; Keane, Joseph
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errSave
A 15 year Retrospective Analysis of the Impact of Hearing Loss following IV Aminoglycoside use for Multi-Drug Resistant Tuberculosis
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2023-10-27
err0
PREAI
errOttewill, Ciara; Maharaj, Tobias; Kane, Maria; Dolan, Lorraine; Keane, Joseph; Mclaughlin, Anne Marie
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errSave
Immunosuppressed Pets as a Conduit for Zoonotic Tuberculosis
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2023-09-15
err0
PREAI
errOttewill, Ciara; Dolan, Lorraine; Lopez-Bailen, Esther; Roycroft, Emma; Fitzgibbon, Margaret; Donohue, Emer O.; McLaughlin, Anne Marie; McGrath, Guy; Keane, Joseph
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errSave
Chronic IFNα treatment induces leukopoiesis, increased plasma succinate and immune cell metabolic rewiring
errCELLULAR IMMUNOLOGY
IF2.9
err2023-08-01
err4
errOAAI
errYennemadi, Anjali S.; Jameson, Grainne; Glass, Mary; De Pasquale, Carolina; Keane, Joseph; Bianchi, Massimiliano; Leisching, Gina
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errSave
A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-03-15
err21
errOAAI
errBedard, Melissa; van der Niet, Sanne; Bernard, Elliott M.; Babunovic, Gregory; Cheng, Tan-Yun; Aylan, Beren; Grootemaat, Anita E.; Raman, Sahadevan; Botella, Laure; Ishikawa, Eri; O'Sullivan, Mary P.; Mayfield, Jacob A.; O'Leary, Seonadh; Buter, Jeffrey; Minnaard, Adriaan J.; Fortune, Sarah M.; Murphy, Leon O.; Ory, Daniel S.; Keane, Joseph; Yamasaki, Sho; Gutierrez, Maximiliano G.; van der Wel, Nicole; Moody, D. Branch
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errSave
Immunocompromised Host Pneumonia: Definitions and Diagnostic Criteria An Official American Thoracic Society Workshop Report
errANNALS OF THE AMERICAN THORACIC SOCIETY
IF5.4
err2023-03-01
err16
errOAAI
errCheng, Guang-Shing; Crothers, Kristina; Aliberti, Stefano; Bergeron, Anne; Boeckh, Michael; Chien, Jason W.; Cilloniz, Catia; Cohen, Keira; Dean, Nathan; Dela Cruz, Charles S.; Dickson, Robert P.; Greninger, Alexander L.; Hage, Chadi A.; Hohl, Tobias M.; Holland, Steven M.; Jones, Barbara E.; Keane, Joseph; Metersky, Mark; Miller, Rachel; Puel, Anne; Ramirez, Julio; Restrepo, Marcos, I; Sheshadri, Ajay; Staitieh, Bashar; Tarrand, Jeffrey; Winthrop, Kevin L.; Wunderink, Richard G.; Evans, Scott E.
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Defining the role of neutrophils in the lung during infection: Implications for tuberculosis disease
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-09-20
err13
errOAAI
errGaffney, E.; Murphy, D.; Walsh, A.; Connolly, S.; Basdeo, S. A.; Keane, J.; Phelan, J. J.
errShare
errSave
Development of Inhalable ATRA-Loaded PLGA Nanoparticles as Host-Directed Immunotherapy against Tuberculosis
errPHARMACEUTICS
IF5.5
err2022-08-21
err15
errOAAI
errBahlool, Ahmad Z.; Fattah, Sarinj; O'Sullivan, Andrew; Cavanagh, Brenton; MacLoughlin, Ronan; Keane, Joseph; O'Sullivan, Mary P.; Cryan, Sally-Ann
errShare
errSave
Diagnostic Performance of Xpert MTB/RIF Ultra Compared with Predecessor Test, Xpert MTB/RIF, in a Low TB Incidence Setting: a Retrospective Service Evaluation
errMICROBIOLOGY SPECTRUM
IF3.8
err2022-06-29
err6
errOAAI
errMansfield, Mary; McLaughlin, Anne Marie; Roycroft, Emma; Montgomery, Lorraine; Keane, Joseph; Fitzgibbon, Margaret M.; Rogers, Thomas R.
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errSave

Research Directions

No research directions
Co-authors
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Douglas T. Golenbock
H-index: 127 · Papers: 351
J
John G. McHutchison
H-index: 125 · Papers: 1.1K
M
Michael Boeckh
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