Jay W. Hooper - Publications, H-index & Citations

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Jay W. Hooper

united states department of energy (doe)

51H-index

148Paper Count

8.2KCitation Count

Published Papers 74

Publication Date

An mRNA vaccine encoding the Ebola virus glycoprotein induces high neutralizing antibody titers and provides strong protection against lethal infections in mouse models

Frontiers in Immunology

IF5.9

2026-01-05

OAAI

Zachary R. Stromberg†; Elvia E. Silva†; Sara C. Johnston; Dylan M. Johnson; Dominique Hall; Emmanuel F. Adjei; John A. Altin; Abisola Abisoye-Ogunniyan; Travis Gollott; Wei He; Iris K. A. Jones; Steve Kwilas; Sean J. Lund; Heather L. Mead; Georgia A. Nelson; Lisa Ouyang; Sandra K. G. Peters; Jennifer L. Schwedler; Caleb Z. Trecazzi; Matthew W. Turner; Chunyan Ye; Steven B. Bradfute; Nicholas O. Fischer; Jay W. Hooper; Jason T. Ladner; Amy Rasley; Oscar A. Negrete

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A Nanolipoprotein Particle Platform Vaccine Targeting Ebola Virus Elicits a Robust Immune Response In Vivo

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Hall, Dominique Elaine; Abisoye-Ogunniyan, Abisola; Mccool, Jillian L.; Grace Peters, Sandra Kay; Vergez, Lisa; Trecazzi, Caleb; He, Wei; Hooper, Jay; Bradfute, Steven B.; Kwilas, Steve; Fischer, Nicholas O.; Rasley, Amy

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CCHFV-M based DNA vaccine is highly immunogenic in multiple species and protects against challenge in cynomolgus macaques

Antiviral Research

IF4

2025-09-13

PREAI

John J. Suschak; Collin J. Fitzpatrick; Charles J. Shoemaker; Joshua D. Shamblin; Lauren E. White; Curtis R. Cline; Christina E. Douglas; Korey L. Delp; Trevor L.A. Burt; Kenise D. Lewis; Suma Ravulapalli; Susan Coyne; Carmen Ledesma-Feliciano; Gregg Wilson; Sarah L.W. Norris; Jennifer L. Scruggs; Ian Davis; Keersten M. Ricks; Christopher P. Stefan; Scott P. Olshner; Xiankun Zeng; Joseph W. Golden; Jay W. Hooper; Aura R. Garrison

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rVSVΔG-ZEBOV-GP Vaccine Is Highly Immunogenic and Efficacious Across a Wide Dose Range in a Nonhuman Primate EBOV Challenge Model

VIRUSES-BASEL

IF3.5

2025-02-28

OAAI

Shurtleff, Amy C.; Trefry, John C.; Dubey, Sheri; Sunay, Melek M. E.; Liu, Kenneth; Chen, Ziqiang; Eichberg, Michael; Silvera, Peter M.; Kwilas, Steve A.; Hooper, Jay W.; Martin, Shannon; Simon, Jakub K.; Coller, Beth-Ann G.; Monath, Thomas P.

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Mpox mRNA-1769 vaccine inhibits orthopoxvirus replication at intranasal, intrarectal, and cutaneous sites of inoculation

NPJ VACCINES

IF6.5

2024-12-24

OAAI

Cotter, Catherine A.; Ignacio, Maxinne A.; Americo, Jeffrey L.; Earl, Patricia L.; Mucker, Eric M.; Frey, Tiffany R.; Carfi, Andrea; Hooper, Jay W.; Freyn, Alec W.; Moss, Bernard

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Phase 1 clinical trial of Hantaan and Puumala virus DNA vaccines delivered by needle-free injection

NPJ VACCINES

IF6.5

2024-11-17

OAAI

Hooper, Jay W.; Kwilas, Steven A.; Josleyn, Matthew; Norris, Sarah; Hutter, Jack N.; Hamer, Melinda; Livezey, Jeffrey; Paolino, Kristopher; Twomey, Patrick; Koren, Michael; Keiser, Paul; Moon, James E.; Nwaeze, Ugo; Koontz, Jason; Ledesma-Feliciano, Carmen; Landry, Nathalie; Wellington, Trevor

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Preclinical evaluation of a fully human, quadrivalent-hantavirus polyclonal antibody derived from a non-human source

MBIO

IF4.7

2024-10-16

OAAI

Brocato, Rebecca L.; Wu, Hua; Kwilas, Steven A.; Principe, Lucia M.; Josleyn, Matthew; Shamblin, Joshua; Chivukula, Padmanabh; Bausch, Christoph; Luke, Thomas; Sullivan, Eddie J.; Hooper, Jay W.

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Glycoprotein-Specific Polyclonal Antibodies Targeting Machupo Virus Protect Guinea Pigs against Lethal Infection

VACCINES

IF3.4

2024-06-18

OAAI

Golden, Joseph W.; Kwilas, Steven A.; Hooper, Jay W.

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Safety and Immunogenicity of an Accelerated Ebola Vaccination Schedule in People with and without Human Immunodeficiency Virus: A Randomized Clinical Trial

VACCINES

IF3.4

2024-05-04

OAAI

Ake, Julie A.; Paolino, Kristopher; Hutter, Jack N.; Cicatelli, Susan Biggs; Eller, Leigh Anne; Eller, Michael A.; Costanzo, Margaret C.; Paquin-Proulx, Dominic; Robb, Merlin L.; Tran, Chi L.; Anova, Lalaine; Jagodzinski, Linda L.; Ward, Lucy A.; Kilgore, Nicole; Rusnak, Janice; Bounds, Callie; Badorrek, Christopher S.; Hooper, Jay W.; Kwilas, Steven A.; Ilsbroux, Ine; Anumendem, Dickson Nkafu; Gaddah, Auguste; Shukarev, Georgi; Bockstal, Viki; Luhn, Kerstin; Douoguih, Macaya; Robinson, Cynthia

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Safety and Immunogenicity of Accelerated Heterologous 2-Dose Ebola Vaccine Regimens in Adults With and Without Human Immunodeficiency Virus in Africa

CLINICAL INFECTIOUS DISEASES

IF7.3

2024-04-24

PREAI

Mwesigwa, Betty; Sawe, Fredrick; Oyieko, Janet; Mwakisisile, Joel; Viegas, Edna; Akintunde, Gideon Akindiran; Kosgei, Josphat; Kokogho, Afoke; Ntinginya, Nyanda; Jani, Ilesh; Shukarev, Georgi; Hooper, Jay W.; Kwilas, Steven A.; Ward, Lucy A.; Rusnak, Janice; Bounds, Callie; Overman, Rachel; Badorrek, Christopher S.; Eller, Leigh Anne; Eller, Michael A.; Polyak, Christina S.; Moodley, Amber; Tran, Chi L.; Costanzo, Margaret C.; Leggat, David J.; Paquin-Proulx, Dominic; Naluyima, Prossy; Anumendem, Dickson Nkafu; Gaddah, Auguste; Luhn, Kerstin; Hendriks, Jenny; McLean, Chelsea; Douoguih, Macaya; Kibuuka, Hannah; Robb, Merlin L.; Robinson, Cynthia; Ake, Julie A.

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Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability

CLINICAL MICROBIOLOGY AND INFECTION

IF8.5

2023-12-01

OAAI

Huttner, Angela; Agnandji, Selidji Todagbe; Engler, Olivier; Hooper, Jay W.; Kwilas, Steve; Ricks, Keersten; Clements, Tamara L.; Jonsdottir, Hulda R.; Nakka, Sravya Sowdamini; Rothenberger, Sylvia; Kremsner, Peter; Zust, Roland; Medaglini, Donata; Ottenhoff, Tom; Harandi, Ali M.; Siegrist, Claire-Anne

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An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-10-04

PREAI

Freyn, Alec W.; Atyeo, Caroline; Earl, Patricia L.; Americo, Jeffrey L.; Chuang, Gwo-Yu; Natarajan, Harini; Frey, Tiffany R.; Gall, Jason G.; Moliva, Juan I.; Hunegnaw, Ruth; Arunkumar, Guha Asthagiri; Ogega, Clinton O.; Nasir, Arshan; Santos, Genesis; Levin, Rafael H.; Meni, Anusha; Jorquera, Patricia A.; Bennett, Hamilton; Johnson, Joshua A.; Durney, Michael A.; Stewart-Jones, Guillaume; Hooper, Jay W.; Colpitts, Tonya M.; Alter, Galit; Sullivan, Nancy J.; Carfi, Andrea; Moss, Bernard

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Development of a specific MPXV antigen detection immunodiagnostic assay

FRONTIERS IN MICROBIOLOGY

IF4.5

2023-09-07

OAAI

Davis, Ian; Payne, Jackie M.; Olguin, Victoria L.; Sanders, Madison P.; Clements, Tamara; Stefan, Christopher P.; Williams, Janice A.; Hooper, Jay W.; Huggins, John W.; Mucker, Eric M.; Ricks, Keersten M.

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Safety and Immunogenicity of an Andes Virus DNA Vaccine by Needle-Free Injection: A Randomized, Controlled Phase 1 Study

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2023-06-28

PREAI

Paulsen, Grant C.; Frenck Jr, Robert; Tomashek, Kay M.; Alarcon, Rodolfo M.; Hensel, Elizabeth; Lowe, Ashley; Brocato, Rebecca L.; Kwilas, Steve A.; Josleyn, Matthew D.; Hooper, Jay W.

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Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

ELIFE

IF0

2023-03-27

OAAI

Engdahl, Taylor B.; Binshtein, Elad; Brocato, Rebecca L.; Kuzmina, Natalia A.; Principe, Lucia M.; Kwilas, Steven A.; Kim, Robert K.; Chapman, Nathaniel S.; Porter, Monique S.; Guardado-Calvo, Pablo; Rey, Felix A.; Handal, Laura S.; Diaz, Summer M.; Zagol-Ikapitte, Irene A.; Tran, Minh H.; McDonald, W. Hayes; Meiler, Jens; Reidy, Joseph X.; Trivette, Andrew; Bukreyev, Alexander; Hooper, Jay W.; Crowe, James E.

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Improved DNA Vaccine Delivery with Needle-Free Injection Systems

VACCINES

IF3.4

2023-01-28

OAAI

Ledesma-Feliciano, Carmen; Chapman, Ros; Hooper, Jay W.; Elma, Kira; Zehrung, Darin; Brennan, Miles B.; Spiegel, Erin K.

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Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-09-14

OAAI

Ji, Yun; Zhang, Qi; Cheng, Lin; Ge, Jiwan; Wang, Ruoke; Fang, Mengqi; Mucker, Eric M.; Chen, Peng; Ma, Ji; Zhang, Rui; Li, Chunming; Hammond, Holly; Baracco, Lauren; Holbrook, Michael; Frieman, Matthew; Zhang, Zheng; Wang, Xinquan; Hooper, Jay W.; Zhang, Linqi; Zhu, Qing

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SARS-CoV-2 Doggybone DNA Vaccine Produces Cross-Variant Neutralizing Antibodies and Is Protective in a COVID-19 Animal Model

VACCINES

IF3.4

2022-07-09

OAAI

Mucker, Eric M.; Brocato, Rebecca L.; Principe, Lucia M.; Kim, Robert K.; Zeng, Xiankun; Smith, Jeffrey M.; Kwilas, Steven A.; Kim, Sungwon; Horton, Helen; Caproni, Lisa; Hooper, Jay W.

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Lipid nanoparticle delivery of unmodified mRNAs encoding multiple monoclonal antibodies targeting poxviruses in rabbits

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2022-06-01

OAAI

Mucker, Eric M.; Thiele-Suess, Carolin; Baumhof, Patrick; Hooper, Jay W.

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Exposure Route Influences Disease Severity in the COVID-19 Cynomolgus Macaque Model

VIRUSES-BASEL

IF3.5

2022-05-10

OAAI

Bixler, Sandra L.; Stefan, Christopher P.; Jay, Alexandra N.; Rossi, Franco D.; Ricks, Keersten M.; Shoemaker, Charles J.; Moreau, Alicia M.; Zeng, Xiankun; Hooper, Jay W.; Dyer, David N.; Frick, Ondraya M.; Koehler, Jeffrey W.; Kearney, Brian J.; DiPinto, Nina; Liu, Jun; Tostenson, Samantha D.; Clements, Tamara L.; Smith, Jeffrey M.; Johnson, Joshua A.; Berrier, Kerry L.; Esham, Heather L.; Delp, Korey L.; Coyne, Susan R.; Bloomfield, Holly A.; Kuehnert, Paul A.; Akers, Kristen; Gibson, Kathleen M.; Minogue, Timothy D.; Nalca, Aysegul; Pitt, Margaret L. M.

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Research Directions