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Christopher Hoimes

harvard university medical affiliates

41H-index
361Paper Count
7.9KCitation Count
Published Papers 60
Publication Date
Efficacy of erdafitinib before or after enfortumab vedotin in FGFR3-altered advanced urothelial cancer: analysis of the UNITE collaborative study
err2025-11-01
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PREAI
errJiang, Cindy Y.; Hwang, Hyunsoo; Epstein, Ilana Y.; Bakaloudi, Dimitra Rafailia; Talukder, Rafee; Taylor, Amy K.; Nizam, Amanda; Jindal, Tanya; Glover, Michael J.; Khaki, Ali Raza; Barata, Pedro C.; Nguyen, Charles B.; Oh, Eugene; Davis, Nancy B.; Mabey, Hannah; Hoimes, Christopher J.; Evans, Sean T.; Abuqayas, Bashar; Lemke, Emily; Tsung, Irene; Qiao, Wei; Kilari, Deepak; Zakharia, Yousef; Bilen, Mehmet A.; Milowsky, Matthew, I; Shah, Sumit A.; Gupta, Shilpa; Emamekhoo, Hamid; Bellmunt, Joaquim; Alva, Ajjai S.; Grivas, Petros; Msaouel, Pavlos; Koshkin, Vadim S.; Campbell, Matthew T.; Alhalabi, Omar
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Treatment-Related Adverse Events and Associated Outcomes in Patients With Advanced Urothelial Carcinoma Treated With Enfortumab Vedotin: Analysis of the UNITE Study
err2025-10-02
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errOAAI
errNizam, Amanda; Nguyen, Charles B.; Li, Jinju; Zabor, Emily C.; Msaouel, Pavlos; Jiang, Cindy Y.; Alhalabi, Omar; Oh, Eugene; Davidsohn, Matthew P.; Epstein, Ilana B.; Bakaloudi, Dimitra Rafailia; Talukder, Rafee; Jindal, Tanya; Taylor, Amy K.; Glover, Michael J.; Khaki, Ali Raza; Lemke, Emily; Mabey, Hannah; Abuqayas, Bashar; Jang, Albert; Brown, Jason R.; Evans, Sean T.; Pywell, Cameron; Basu, Arnab; Bilen, Mehmet A.; Barata, Pedro C.; Zakharia, Yousef; Milowsky, Matthew I.; Kilari, Deepak; Hoimes, Christopher J.; Shah, Sumit A.; Emamekhoo, Hamid; Davis, Nancy B.; Gupta, Shilpa; Grivas, Petros; Bellmunt, Joaquim; Campbell, Matthew T.; Alva, Ajjai S.; Koshkin, Vadim S.
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A Phase 1, multiple-dose study to evaluate the safety and tolerability of first-in-class XmAb819 (ENPP3 x CD3) in subjects with relapsed or refractory clear cell renal cell carcinoma (ccRCC) (NCT05433)
err2025-10-01
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errOAAI
errBohac, Chet; Pal, Sumanta; Sweis, Randy; Kotecha, Ritesh; Runcie, Karie; Bilen, Mehmet; Braun, David; Tykodi, Scott; Hoimes, Christopher; Suri, Vithika; Kanodia, Jitendra; Salama, Engie; Woo, Jacky; Li, Lingling; Yang, Yuanquan; Franklin, Robert; Maly, Joseph; Grigg, Claud; Gulati, Shuchi; Vanderweele, David J.; Garmezy, Benjamin
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Outcomes with Enfortumab Vedotin in Patients with Histologic Subtypes of Advanced Urothelial Carcinoma: Analysis of the UNITE Study
err2025-09-14
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PREAI
errTanya Jindal; Cindy Y. Jiang; Omar Alhalabi; Charles B. Nguyen; Eugene Oh; Irene Tsung; Dimitra Rafailia Bakaloudi; Rafee Talukder; Matthew Davidsohn; Dory Freeman; Ilana Y. Epstein; Chien-Kuang Cornelia Ding; Amanda Nizam; Michael J. Glover; Ali Raza Khaki; Amy K. Taylor; Emily Lemke; Albert Jang; Sean T. Evans; Denny Shin; Cameron Pywell; Arnab Basu; Mehmet A. Bilen; Yousef Zakharia; Pedro Barata; Matthew I. Milowsky; Jason Brown; Deepak Kilari; Hamid Emamekhoo; Christopher J. Hoimes; Sumit Shah; Nancy B. Davis; Shilpa Gupta; Petros Grivas; Joaquim Bellmunt; Ajjai Alva; Matthew T. Campbell; Vadim S. Koshkin
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Phase 1b/2 study of batiraxcept alone and in combination with cabozantinib with or without nivolumab for advanced clear cell renal cell carcinoma
err2025-06-01
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PREAI
errBeckermann, Kathryn E.; Shah, Neil J.; Campbell, Matthew T.; Haas, Naomi B.; Nelson, Ariel; Ornstein, Moshe C.; Mao, Shifeng; Keshava-Prasad, Holavanahalli S.; Hammers, Hans; Gao, Xin; Gourdin, Theodore; George, Saby; Hoimes, Christopher J.; Hussain, Arif; Jonasch, Eric; Rini, Brian, I; Voss, Martin H.
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Genomic Biomarkers Associated with Enfortumab Vedotin Outcomes for Patients with Advanced Urothelial Carcinoma: Analysis of UNITE Study Data
err2024-12-01
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errOAAI
errJindal, Tanya; Jiang, Cindy; Alhalabi, Omar; Nizam, Amanda; Nguyen, Charles; Talukder, Rafee; Bakaloudi, Dimitra; Davidsohn, Matthew; Freeman, Dory; Glover, Michael; Khaki, Ali Raza; Evans, Sean; Lemke, Emily; Bose, Rohit; Sim, Woogwang; Pywell, Cameron; Basu, Arnab; Kilari, Deepak; Barata, Pedro C.; Bilen, Mehmet A.; Zakharia, Yousef; Milowsky, Matthew I.; Shah, Sumit A.; Bellmunt, Joaquim; Grivas, Petros; Emamekhoo, Hamid; Davis, Nancy B.; Gupta, Shilpa; Hoimes, Christopher; Campbell, Matthew T.; Alva, Ajjai; Koshkin, Vadim S.
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Preliminary safety and anti-tumor activity of TYRA-300, a highly selective FGFR3 inhibitor, in participants with advanced solid tumors with activating FGFR3 mutations/fusions (SURF301)
err2024-10-01
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PREAI
errTran, B.; Boni, A.; Hansen, A.; Boni, V.; Mantia, C.; Yu, E.; Weickhardt, A.; Robert, M.; Gupta, S.; Necchi, A.; Morales-Barrera, R.; Hoimes, C.; Berlin, J.; Iyer, G.; Millward, M.; Burn, T.; Lihou, C.; Gammon, G.; Rosenberg, J.; Loriot, Y.
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A Multicenter, Open-label Phase 1/2 Study of TYRA 300 in Advanced Urothelial Carcinoma and Other Solid Tumors with Activating FGFR3 Gene Alterations (SURF301)
err2024-10-01
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PREAI
errZhang, A.; Boni, V.; Hanson, A.; Mantia, C.; Weickhardt, A.; Yu, E.; Gupta, S.; Robert, M.; Iyer, G.; Millward, M.; Morales-Barrera, R.; Hoimes, C.; Berlin, J.; Mittal, K.; Hill, A.; Racca, F.; Pouessel, D.; Lihou, C.; Tran, B.; Loriot, Y.
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Pre-treatment (Tx) risk factors for enfortumab vedotin-induced peripheral neuropathy (EVIPN) in patients (pts) with advanced urothelial carcinoma (aUC): Analysis of UNITE
err2024-09-01
err0
PREAI
errNizam, A.; Zhang, L.; Jiang, C. Y.; Nguyen, C. B.; Bakaloudi, D. R.; Bilen, M. A.; Barata, P. M. Coelho; Zakharia, Y.; Milowsky, M. I.; Kilari, D.; Hoimes, C. J.; Khaki, A. R.; Emamekhoo, H.; Gupta, S.; Grivas, P.; Bellmunt, J.; Alva, A. S.; Campbell, M. T.; Alhalabi, O.; Koshkin, V. S.
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Efficacy of enfortumab vedotin (EV) in patients (pts) with (w) advanced urothelial carcinoma (aUC) who have baseline neuropathy (N) and/or diabetes mellitus (DM): A UNITE study analysis
err2024-09-01
err0
PREAI
errJang, A.; Jindal, T.; Jiang, C. Y.; Nguyen, C. B.; Nizam, A.; Alva, A. S.; Grivas, P.; Bellmunt, J.; Hoimes, C. J.; Bilen, M. A.; Emamekhoo, H.; Milowsky, M. I.; Khaki, A. R.; Gupta, S.; Campbell, M. T.; Alhalabi, O.; Chen, Z.; Fu, P.; Koshkin, V. S.; Brown, J. R.
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Enfortumab vedotin (EV) plus pembrolizumab (P) outcomes outside clinical trials and biomarkers of benefit in patients (pts) with advanced urothelial carcinoma: Analysis of the UNITE study
err2024-09-01
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PREAI
errJindal, T.; Jiang, C. Y.; Alhalabi, O.; Tsung, I.; Jang, A.; Bakaloudi, D. R.; Sidhom, F.; Taylor, A. K.; Hoimes, C. J.; Bellmunt, J.; Bilen, M. A.; Gupta, S.; Milowsky, M. I.; Shah, S.; Basu, A.; Grivas, P.; Brown, J. R.; Campbell, M. T.; Alva, A. S.; Koshkin, V. S.
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Study EV-103 dose escalation/cohort A (DE/A): 5y follow-up of first-line (1L) enfortumab vedotin (EV) plus pembrolizumab (P) in cisplatin (CIS)-ineligible locally advanced or metastatic urothelial carcinoma (la/mUC)
err2024-09-01
err2
PREAI
errRosenberg, J. E.; Petrylak, D. P.; Flaig, T.; Hoimes, C. J.; Gupta, S.; O'Donnell, P. H.; Mar, N.; Friedlander, T.; Tagawa, S. T.; Bilen, M. A.; Brown, J. R.; McKay, R. R.; Merchan, J. R.; Srinivas, S.; Shetty, A.; Homet Moreno, B.; Davis, G.; Wirtz, H.; Zhu, Y.; Milowsky, M. I.
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Pembrolizumab plus enzalutamide for metastatic castration-resistant prostate cancer progressing on enzalutamide: cohorts 4 and 5 of the phase 2 KEYNOTE-199 study
err2024-08-12
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PREAI
errGraff, Julie N.; Hoimes, Christopher J.; Gerritsen, Winald R.; Vaishampayan, Ulka N.; Elliott, Tony; Hwang, Clara; ten Tije, Albert J.; Omlin, Aurelius; McDermott, Raymond S.; Fradet, Yves; Tagawa, Scott T.; Kilari, Deepak; Ferrario, Cristiano; Uemura, Hiroji; Jones, Robert J.; Fukasawa, Satoshi; Peer, Avivit; Niu, Cuizhen; Poehlein, Christian H.; Qiu, Ping; Suttner, Leah; de Wit, Ronald; Schloss, Charles; de Bono, Johann S.; Antonarakis, Emmanuel S.
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A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma
err2024-08-01
err2
PREAI
errMsaouel, Pavlos; Sweis, Randy F.; Bupathi, Manojkumar; Heath, Elisabeth; Goodman Jr, Oscar B.; Hoimes, Christopher J.; Milowsky, Matthew I.; Davis, Nancy; Kalebasty, Arash Rezazadeh; Picus, Joel; Shaffer, David; Mao, Shifeng; Adra, Nabil; Yorio, Jeffrey; Gandhi, Sunil; Grivas, Petros; Siefker-Radtke, Arlene; Yang, Rui; Latven, Lisa; Olson, Peter; Chin, Curtis D.; Der-Torossian, Hirak; Mortazavi, Amir; Iyer, Gopa
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Safety and efficacy outcomes of early cessation of anti-PD1 therapy in patients 80 years or older: A retrospective cohort study
err2024-08-01
err2
errOAAI
errFletcher, Kylie; Cortellini, Alessio; Ganta, Teja; Kankaria, Roma; Song, Haocan; Ye, Fei; Irlmeier, Rebecca; Debnath, Neha; Saeed, Anwaar; Radford, Maluki; Alahmadi, Asrar; Diamond, Akiva; Hoimes, Christopher; Presley, Carolyn J.; Owen, Dwight H.; Abou Alaiwi, Sarah; Nassar, Amin H.; Lamberti, Giuseppe; Perrone, Fabiana; Buti, Sebastiano; Giusti, Raffaele; Filetti, Marco; Vanella, Vito; Mallardo, Domenico; Sussman, Tamara A.; Galetta, Domenico; Kalofonou, Foteini; Daniels, Ella; Ascierto, Paolo A.; Pinato, David J.; Nebhan, Caroline; Berg, Stephanie; Choueiri, Toni K.; Marron, Thomas U.; Wang, Yinghong; Naqash, Abdul Rafeh; Johnson, Douglas B.
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Association of Tumor-informed Circulating Tumor DNA Detectability Before and After Radical Cystectomy with Disease-free Survival in Patients with Bladder Cancer
err2024-07-01
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errOAAI
errJohn P. Sfakianos; Arnab Basu; George Laliotis; Shivaram Cumarasamy; Jordan M. Rich; Ajitha Kommalapati; Michael Glover; Tamara Mahmood; Neeraja Tillu; Christopher J. Hoimes; Grayce Selig; Revathi Kollipara; Tyler F. Stewart; Samuel Rivero-Hinojosa; Punashi Dutta; Mark Calhoun; Shruti Sharma; Meenakshi Malhotra; Adam C. ElNaggar; Minetta C. Liu; James E. Ferguson; Marcio Diniz; Reza Mehrazin; Peter Wiklund; Alan Tan; Sumit Shah; Matthew D. Galsky
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Initial results from a phase 1a/1b study of STK-012, a first-in-class α/β IL-2 receptor biased partial agonist in advanced solid tumors (NCT05098132)
err2024-04-05
err1
PREAI
errIzar, Benjamin; Zamarin, Dmitriy; Spigel, David R.; Hoimes, Christopher J.; McDermott, David F.; Sehgal, Kartik; Najjar, Yana G.; Schoenfeld, Adam J.; Garon, Edward B.; Sullivan, Ryan J.; Henick, Brian S.; Leal, Ticiana A.; Hurwitz, Michael E.; McKay, Rana R.; Busby, Natalie; Mehta-Damani, Anita; Azrilevich, Alex; Tran, Tony; Rizvi, Naiyer; Oft, Martin; Spira, Alexander I.
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Intratumoural immunotherapy plus focal thermal ablation for localized prostate cancer
err2023-12-19
err4
PREAI
errSeguier, Denis; Adams, Eric S.; Kotamarti, Srinath; D'Anniballe, Vincent; Michael, Zoe D.; Deivasigamani, Sriram; Olivier, Jonathan; Villers, Arnauld; Hoimes, Christopher; Polascik, Thomas J.
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A plain language summary exploring a new treatment combination for untreated locally advanced or metastatic urothelial cancer: enfortumab vedotin plus pembrolizumab
err2023-11-23
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errOAAI
errHoimes, Christopher J.; Flaig, Thomas W.; Milowsky, Matthew, I; Friedlander, Terence W.; Bilen, Mehmet Asim; Gupta, Shilpa; Srinivas, Sandy; Merchan, Jaime R.; Mckay, Rana R.; Petrylak, Daniel P.; Sasse, Carolyn; Moreno, Blanca Homet; Yu, Yao; Carret, Anne-Sophie; Rosenberg, Jonathan E.
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Phase Ib/II study of batiraxcept (BT, AVB-S6-500, an AXL pathway inhibitor) in combination with cabozantinib (cabo) in patients with advanced clear cell renal cell carcinoma (ccRCC) who failed first-line (1L) therapy
err2023-10-01
err1
errOAAI
errShah, N. J.; Campbell, M. T.; Mao, S.; Ornstein, M. C.; Haas, N. B.; Gao, X.; Hammers, H.; Keshava-Prasad, H.; Hoimes, C. J.; Hussain, A.; George, S.; Gourdin, T. S.; Nelson, A.; Yan, H.; Esquibel, V.; McIntyre, G.; Geller, R.; Voss, M. H.; Rini, B. I.; Beckermann, K.
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