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A Phase Ia/b study of MEK1/2 inhibitor binimetinib with MET inhibitor crizotinib in patients with RAS mutant advanced colorectal cancer (MErCuRIC) Aroldi, Francesca; Elez, Elena; Andre, Thierry; Perkins, Geraldine; Prenen, Hans; Popovici, Vlad; Gallagher, Peter; Houlden, Jennifer; Collins, Linda; Roberts, Corran; Rolfo, Christian; Di Nicolantonio, Federica; Grayson, Margaret; Boyd, Ruth; Bettens, Karolien; Delfavero, Jurgen; Coyle, Victoria; Lawler, Mark; Khawaja, Hajrah; Laurent-Puig, Pierre; Salto-Tellez, Manuel; Maughan, Tim S.; Tabernero, Josep; Adams, Richard; Jones, Robert; Hennessy, Bryan T.; Bardelli, Alberto; Peeters, Marc; Middleton, Mark R.; Wilson, Richard H.; Van Schaeybroeck, Sandra Share Save
Quantitative liver function imaging and whole genome sequencing - Effective modalities for a new era in personalised decision-making for operable colorectal liver metastases? Welsh, Fenella; Sundaravadanan, Senthil; Sethi, Pulkit; Kazeroun, Mohammad; Fichera, Alessandro; Nadziruddin, Irdina; Larkin, Sarah J.; Ansari-Pour, Naser; Maughan, Tim; Brady, Michael; Banerjee, Rajarshi; Gooding, Sarah; Rees, Myrddin Share Save
Standard or high dose chemoradiotherapy, with or without the protease inhibitor nelfinavir, in patients with locally advanced pancreatic cancer: The phase 1/randomised phase 2 SCALOP-2 trial Mukherjee, Somnath; Qi, Cathy; Shaw, Rachel; Jones, Christopher M.; Bridgewater, John A.; Radhakrishna, Ganesh; Patel, Neel; Holmes, Jane; Virdee, Pradeep S.; Tranter, Bethan; Parsons, Philip; Falk, Stephen; Wasan, Harpreet S.; Ajithkumar, Thankamma, V; Holyoake, Daniel; Roy, Rajarshi; Scott-Brown, Martin; Hurt, Christopher N.; O'Neill, Eric; Sebag-Montefiore, David; Maughan, Tim S.; Hawkins, Maria A.; Corrie, Pippa Share Save
Encorafenib plus cetuximab (EC) plus FOLFIRI for BRAF V600E-mutant metastatic colorectal cancer (mCRC): Updated results from the BREAKWATER safety lead-in (SLI) Tabernero, J.; Yoshino, T.; Kim, T. W.; Yaeger, R.; Desai, J.; Wasan, H. S.; Van Cutsem, E.; Ciardiello, F.; Maughan, T.; Eng, C.; Tie, J.; Elez Fernandez, M. E.; Lonardi, S.; Usari, T.; Hahn, E.; Dychter, S.; Ferrier, G.; Zhang, X.; Kopetz, S. Share Save
Stereotactic Magnetic Resonance-Guided Daily Adaptive SABR (SMART) for Localised Non-Metastatic Pancreatic Cancer: First Reported Clinical Outcomes From the UK Nugent, K.; Mukherjee, S.; Teoh, S.; George, B.; Martin, A.; Gaya, A.; Aznar-Garcia, L.; Chu, K.; Robinson, M.; Maughan, T.; Good, J. Share Save
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1 (vol 133, e168277, 2023) Beach, Callum; MacLean, David; Majorova, Dominika; Melemenidis, Stavros; Nambiar, Dhanya K.; Kim, Ryan K.; Valbuena, Gabriel N.; Guglietta, Silvia; Krieg, Carsten; Darvish-Damavandi, Mahnaz; Suwa, Tatsuya; Easton, Alistair; Hillson, Lily V. S.; McCulloch, Ashley K.; McMahon, Ross K.; Pennel, Kathryn; Edwards, Joanne; O'Cathail, Sean M.; Roxburgh, Campbell S.; Domingo, Enric; Moon, Eui Jung; Jiang, Dadi; Jiang, Yanyan; Zhang, Qingyang; Koong, Albert C.; Woodruff, Trent M.; Graves, Edward E.; Maughan, Tim; Buczacki, Simon J. A.; Stucki, Manuel; Le, Quynh-Thu; Leedham, Simon J.; Giaccia, Amato J.; Olcina, Monica M. Share Save
Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy Lafarge, Maxime W.; Domingo, Enric; Sirinukunwattana, Korsuk; Wood, Ruby; Samuel, Leslie; Murray, Graeme; Richman, Susan D.; Blake, Andrew; Sebag-Montefiore, David; Gollins, Simon; Klieser, Eckhard; Neureiter, Daniel; Huemer, Florian; Greil, Richard; Dunne, Philip; Quirke, Philip; Weiss, Lukas; Rittscher, Jens; Maughan, Tim; Koelzer, Viktor H. Share Save
New role of fat-free mass in cancer risk linked with genetic predisposition Harris, Benjamin H. L.; Di Giovannantonio, Matteo; Zhang, Ping; Harris, David A.; Lord, Simon R.; Allen, Naomi E.; Maughan, Tim S.; Bryant, Richard J.; Harris, Adrian L.; Bond, Gareth L.; Buffa, Francesca M. Share Save
Fluoropyrimidine type, patient age, tumour sidedness and mutation status as determinants of benefit in patients with metastatic colorectal cancer treated with EGFR monoclonal antibodies: individual patient data pooled analysis of randomised trials from the ARCAD database Karapetis, C. S.; Liu, H.; Sorich, M. J.; Pederson, L. D.; Van Cutsem, E.; Maughan, T.; Douillard, J. Y.; O'Callaghan, C. J.; Jonker, D.; Bokemeyer, C.; Sobrero, A.; Cremolini, C.; Chibaudel, B.; Zalcberg, J.; Adams, R.; Buyse, M.; Peeters, M.; Yoshino, T.; de Gramont, A.; Shi, Q. Share Save
CHARIOT: a phase I study of berzosertib with chemoradiotherapy in oesophageal and other solid cancers using time to event continual reassessment method Javed, S. R.; Lord, S.; El Badri, S.; Harman, R.; Holmes, J.; Kamzi, F.; Maughan, T.; McIntosh, D.; Mukherjee, S.; Ooms, A.; Radhakrishna, G.; Shaw, P.; Hawkins, M. A. Share Save
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1 Beach, Callum; MacLean, David; Majorova, Dominika; Melemenidis, Stavros; Nambiar, Dhanya K.; Kim, Ryan K.; Valbuena, Gabriel N.; Guglietta, Silvia; Krieg, Carsten; Darvish-Damavandi, Mahnaz; Suwa, Tatsuya; Easton, Alistair; Hillson, Lily V. S.; McCulloch, Ashley K.; McMahon, Ross K.; Pennel, Kathryn; Edwards, Joanne; O'Cathail, Sean M.; Roxburgh, Campbell S.; Domingo, Enric; Moon, Eui Jung; Jiang, Dadi; Jiang, Yanyan; Zhang, Qingyang; Koong, Albert C.; Woodruff, Trent M.; Graves, Edward E.; Maughan, Tim; Buczacki, Simon J. A.; Stucki, Manuel; Le, Quynh-Thu; Leedham, Simon J.; Giaccia, Amato J.; Olcina, Monica M. Share Save
Efficacy of early PET-CT directed switch to carboplatin and paclitaxel based definitive chemoradiotherapy in patients with oesophageal cancer who have a poor early response to induction cisplatin and capecitabine in the UK: a multi-centre randomised controlled phase II trial Mukherjee, Somnath; Hurt, Christopher N.; Adams, Richard; Bateman, Andrew; Bradley, Kevin M.; Bridges, Sarah; Falk, Stephen; Grif, Gareth; Gwynne, Sarah; Jones, Christopher M.; Markham, PhilipJ.; Maughan, Tim; Nixon, Lisette S.; Radhakrishna, Ganesh; Roy, Rajarshi; Schoenbuchner, Simon; Sheikh, Hamid; Spezi, Emiliano; Hawkins, Maria; Crosby, Thomas D. L. Share Save
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Fluoropyrimidine-induced hand-foot syndrome and cardiotoxicity: recommendations for the use of the oral fluoropyrimidine S-1 in metastatic colorectal cancer Punt, C. J. A.; Heinemann, V.; Maughan, T.; Cremolini, C.; Van Cutsem, E.; McDermott, R.; Bodoky, G.; Andre, T.; Osterlund, P.; Teske, A. J.; Pfeiffer, P. Share Save
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Prediction of poor response to oxaliplatin by an RNA signature derived and validated in colorectal cancer clinical trials Hassanieh, S.; Domingo, E.; Blake, A.; Fisher, D.; Redmond, K. L.; Richman, S. D.; Walker, S. M.; Quirke, P.; Wilson, R. H.; Kennedy, R.; Tomlinson, I.; Kaplan, R. S.; Brown, L.; Dunne, P.; Seymour, M. T.; Morton, D.; Adams, R. A.; West, N.; Maughan, T. Share Save
BREAKWATER safety lead-in (SLI): Encorafenib (E) plus cetuximab (C) plus chemotherapy (chemo) for BRAFV600E metastatic colorectal cancer (mCRC) Tabernero, J.; Yoshino, T.; Kim, T. W.; Yaeger, R.; Desai, J.; Wasan, H. S.; Van Cutsem, E.; Ciardiello, F.; Maughan, T.; Eng, C.; Tie, J.; Fernandez, M. E. Elez; Lonardi, S.; Zhang, X.; Chavira, R.; Usari, T.; Hahn, E.; Kopetz, S. Share Save
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