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Tuan Zea Tan

Center for Translational Medicine

53H-index
390Paper Count
9.6KCitation Count
Published Papers 118
Publication Date
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Spatial transcriptomic profiling of ovarian clear cell carcinoma reveals heterogeneity in OXPHOS and EMT gradients
errNature Communications
IF15.7
err2026-07-08
err0
errOAAI
errThang Truong Le; Duncan Yi-Te Wang; Sebastian Rui-Gu Yan; Yi-Cian Chen; Ko-Chen Chen; Tuan Zea Tan; Pei-Yu Chu; Denis Ting-Hsian Chen; Yi-Chia Chiu; Jia-Yuh Sheu; Sydney Rechie Necesario; Chen-Hao Huang; Jieru Ye; Ya-Ting Tai; Hsueh-Fen Juan; Feng-Chiao Tsai; Wei-Chou Lin; Ying-Cheng Chiang; Lin-Hung Wei; Ruby Yun-Ju Huang
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Mes/Stem-A ovarian cancer subtypes predict sensitivity to ATR inhibition
errOncogene
IF7.3
err2026-06-11
err0
errOAAI
errVignesh Sundararajan; Fang Ziyu; Gamal Ahmed Elfar; Tuan Zea Tan; Kuee Theng Kuay; Agnes Tan; Clemence Lai; Antje Margret Wengner; Huynh The Hung; Maili Qi; Wen Yee Chay; Chit Fang Cheok; David Shao Peng Tan
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errSave
DP103 as a critical modulator of Wnt signaling and cancer stemness: implications for precision treatment in triple negative breast cancer
errCell Death & Disease
IF9.6
err2026-06-05
err0
errOAAI
errWanpei Cai; Sebastian Öther-Gee Pohl; Xianning Lai; Hiu Yan Lam; Catharine Shi-Yun Low; Vivien Koh; Haoran Ma; Mark Agostino; Arindam Banerjee; Nawat Bunnag; Jahnavi Suresh; Amudha Deivasigamani; Yi Yuan; Tuan Zea Tan; Muthukumar Rajasekaran; Jianxiang Chen; Hannah Lee Foon Swa; San Hue Hua; Shiyuan Guo; Janet Cheng-Fei Teng; Jas Min Chin; Jocelyn Yeen Hui Choy; Aye Aye Thike; Young Bok Lee; Madhu Mathi Kanchi; Karthik Ramesh; Yu Keung Mok; Ruby Yun-Ju Huang; Jayantha Gunaratne; Melissa Jane Fullwood; Puay Hoon Tan; George W. Yip; Gautam Sethi; Jeremy P. Blaydes; Celestial T. Yap; Peter Edward Lobie; Venetia Jing-Tong Kok; Arunasalam Dharmarajan; Kam Man Hui; Deog Joong Kim; Jit Kong Cheong; Nicholas Tolwinski; Wei Peng Yong; Patrick Tan; Kevin B. Myant; Alan Prem Kumar
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errSave
XPO1 inhibitor KPT-330 disrupts the core transcriptional regulatory circuitry of dedifferentiated liposarcoma by modulating the translation process
errOncogene
IF7.3
err2026-04-16
err0
PREAI
errXiaorui Fan; Ying Zhang; Zhengming Yang; Tuan Zea Tan; Xingze Huang; Suya Zheng; Jiyang Liu; Long Xie; Ting Tao; Victor Kwanmin Lee; Chao Yu; H. Phillip Koeffler; Ye Chen; Liang Xu
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errSave
Mitochondrial translocation of MDM2 and TFAM reprograms metabolism in treatment-refractory cancers
errnpj Precision Oncology
IF8
err2026-04-16
err0
errOAAI
errJie Qing Eu; Nur Afiqah Binte Mohamed Salleh; Jayshree Hirpara; Naoto Ohi; Emiri Omori Takaki; Tuan Zea Tan; Ju Ee Seet; Susan Swee-Shan Hue; Shu Jun Chan; Dorothy Xi Yue Lim; Lingzhi Wang; Regina Tong Xin Wong; Azhar Ali; Yaw Chyn Lim; Boon-Cher Goh; Li Ren Kong; Shazib Pervaiz; Andrea LA Wong
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errSave
Bioenergetic diversity and nutrient auxotrophy shape the metabolic landscape of Multiple Myeloma
errBlood Advances
IF7.1
err2025-12-02
err0
errOAAI
errPhyllis S.Y. Chong; Lim Sze Lynn Julia; Tuan Zea Tan; Li Ren Kong; Sanjay de Mel; Aaron Leow Chung Yong; Ernest Yap Gim Seng; Wee-Joo Chng
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errSave
Accelerated ageing predicts earlier onset of ischaemic stroke: a proteomic and transcriptomic investigation
errEUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
IF7.5
err2025-11-01
err0
PREAI
errQuek, Amy May Lin; Teng, Ooiean; Tan, Tuan Zea; Park, Ju Hea; Er, Bernadette Guek Cheng; Goh, Jen-Yin; Jing, Mingxue; Tan, Benjamin Yong Qiang; Yeo, Leonard Y.; Chan, Bernard Poon Lap; Teoh, Hock Luen; Oh, Vernon Min Sen; Lim, Erle Chuen Hian; Seet, Raymond Chee Seong
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A phase 1b, multicentre, dose escalation, safety and pharmacokinetics study of tilvestamab (BGB149) in relapsed, platinum-resistant, high-grade serous ovarian cancer (PROC) patients
errBritish Journal of Cancer
IF6.8
err2025-07-22
err0
errOAAI
errKenneth Sooi; Tuan Zea Tan; Jae-Weon Kim; Jung Yun Lee; Byoung-Gie Kim; David Micklem; Akil Jackson; David J. Pinato; Charlie Gourley; Rebecca Kristeleit; Sarah P. Blagden; Line Bjorge; David Shao Peng Tan
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errSave
Elevated uric acid and impaired triglyceride metabolism predict mortality in women after ischemic stroke
errFree Radical Biology and Medicine
IF8.2
err2025-07-09
err0
PREAI
errAmy May Lin Quek; Ooiean Teng; Ju-Hea Park; Jen-Yin Goh; Tuan Zea Tan; Bernadette Guek Cheng Er; Geelyn Jeng Lin Ng; Erle Chuen Hian Lim; Barry Halliwell; Raymond Chee Seong Seet
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errSave
A multi-task domain-adapted model to predict chemotherapy response from mutations in recurrently altered cancer genes
errISCIENCE
IF4.1
err2025-02-01
err0
errOAAI
errJayagopal, Aishwarya; Walsh, Robert J.; Hariprasannan, Krishna Kumar; Mariappan, Ragunathan; Mahapatra, Debabrata; Jaynes, Patrick William; Lim, Diana; Tan, David Shao Peng; Tan, Tuan Zea; Pitt, Jason J.; Jeyasekharan, Anand D.; Rajan, Vaibhav
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errSave
Spatial Profiling of Ovarian Clear Cell Carcinoma Reveals Immune-Hot Features
errMODERN PATHOLOGY
IF5.5
err2025-01-01
err1
errOAAI
errTai, Ya-Ting; Lin, Wei-Chou; Ye, Jieru; Chen, Denis T. -H.; Chen, Ko-Chen; Wang, Duncan Y. -T.; Tan, Tuan Z.; Wei, Lin-Hung; Huang, Ruby Y. -J.
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errSave
Unlocking the circulating immune landscape of advanced clear-cell ovarian cancer: Insights from the MOCCA trial
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errBlanc-Durand, F.; Ngoi, N.; Kaliaperumal, N.; Au, V. Bijin; Talib, N. B. S. N.; Sng, R.; Chong, J.; Choi, C. H.; Zhu, J.; Lim, D.; Tan, T. Z.; Heong, V. Y. M.; Chay, W. Y.; Kim, H. S.; Lim, Y. W.; Kim, J-W.; Tai, B. C.; Kim, K.; Connolly, J.; Tan, D. S.
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errSave
Integrative multi-omics refine molecular diagnostics in nonsmall cell lung cancer
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errKong, L. R.; Han, I.; Teo, J.; Eu, J. Q.; Salleh, N. A. Mohamed; Goh, G.; Huang, Y.; Goh, B-C.; Tan, T. Z.
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errSave
Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma
errNATURE COMMUNICATIONS
IF15.7
err2024-08-09
err0
errOAAI
errXiong, Sinan; Zhou, Jianbiao; Tan, Tze King; Chung, Tae-Hoon; Tan, Tuan Zea; Toh, Sabrina Hui-Min; Tang, Nicole Xin Ning; Jia, Yunlu; See, Yi Xiang; Fullwood, Melissa Jane; Sanda, Takaomi; Chng, Wee-Joo
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Alternative PER2 (Period2) enhancer usage drives epithelial-mesenchymal transition (EMT) in epithelial ovarian cancer (OC)
errCANCER RESEARCH
IF16.6
err2024-03-04
err0
PREAI
errChiu, Yi Chia; Pang, Qing You; Chen, Yu Jie; Tan, Tuan Zea; Ravinath, Divya Malathy; Hwang-Verslues, Wendy; Huang, Ruby Yun Ju
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errSave
Comprehensive characterization of genomic features and clinical outcomes following targeted therapy and secondary cytoreductive surgery in OCCC: a single center experience
errJOURNAL OF GYNECOLOGIC ONCOLOGY
IF3.7
err2024-01-01
err2
errOAAI
errWijaya, Silvana Talisa; Ngoi, Natalie Y. L.; Loh, Jerold W. Z.; Tan, Tuan Zea; Lim, Diana; Khan, Irfan Sagir; Thian, Yee Liang; Lai, Alexa; Ang, Bertrand W. L.; Tong, Pearl; Ng, Joseph; Low, Jeffrey J. H.; Ilancheran, Arunachalam; Lim, Siew Eng; Lim, Yi Wan; Tan, David S. P.
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SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition
errNPJ PRECISION ONCOLOGY
IF8
err2023-12-15
err0
errOAAI
errLai, Xianning; Lui, Sarah Kit Leng; Lam, Hiu Yan; Adachi, Yuta; Sim, Wen Jing; Vasilevski, Natali; Armstrong, Nicola J.; Bridgeman, Stephanie Claire; Main, Nathan Michael; Tan, Tuan Zea; Tirnitz-Parker, Janina E. E.; Thiery, Jean Paul; Ebi, Hiromichi; Kumar, Alan Prem; Eichhorn, Pieter Johan Adam
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errSave
Intrinsic cancer cell phosphoinositide 3-kinase δ regulates fibrosis and vascular development in cholangiocarcinoma
errLIVER INTERNATIONAL
IF5.2
err2023-10-07
err2
errOAAI
errBou Malham, Vanessa; Benzoubir, Nassima; Vaquero, Javier; Desterke, Christophe; Agnetti, Jean; Song, Pei Xuan; Gonzalez-Sanchez, Ester; Arbelaiz, Ander; Jacques, Sophie; Di Valentin, Emanuel; Rahmouni, Souad; Tan, Tuan Zea; Samuel, Didier; Thiery, Jean Paul; Sebagh, Mylene; Fouassier, Laura; Gassama-Diagne, Ama
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errSave
A gene expression signature to predict benefit from intraperitoneal (IP) carboplatin chemotherapy in ovarian carcinoma (OC): Translational research study from the intraperitoneal therapy for ovarian cancer with carboplatin (iPocc) phase II/III trial
errANNALS OF ONCOLOGY
IF65.4
err2023-10-01
err0
PREAI
errTan, D. S.; Tan, T. Z.; Ye, J.; Ngoi, N. Y. L.; Ogasawara, A.; Shintani, D.; Kurosaki, A.; Yamamoto, K.; Jan, Y-H.; Chen, S-J.; Fujiwara, K.; Huang, R.; Hasegawa, K.
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The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer (vol 6, 660, 2023)
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-07-20
err0
errOAAI
errYeo, Xun Hui; Sundararajan, Vignesh; Wu, Zhengwei; Phua, Zi Jin Cheryl; Ho, Yin Ying; Peh, Kai Lay Esther; Chiu, Yi-Chia; Tan, Tuan Zea; Kappei, Dennis; Ho, Ying Swan; Tan, David Shao Peng; Tam, Wai Leong; Huang, Ruby Yun-Ju
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Research Directions

No research directions
Co-authors
Cooperation Journals
G
Gordon B. Mills
H-index: 231 · Papers: 3.5K
B
Barry Halliwell
H-index: 190 · Papers: 946
L
Laurence Zitvogel
H-index: 165 · Papers: 1.2K
N
Neal G. Copeland
H-index: 150 · Papers: 1.0K
P
Peter ten Dijke
H-index: 147 · Papers: 794
View more