Not logged in Sitravatinib in patients with solid tumors selected by molecular alterations: results from a Phase Ib study Bazhenova, Lyudmila; Kim, Dong-Wan; Cho, Byoung Chul; Goel, Sanjay; Heist, Rebecca; Werner, Theresa L.; Eaton, Keith D.; Wang, Judy S.; Pant, Shubham; Adkins, Douglas R.; Blakely, Collin M.; Yan, Xiaohong; Neuteboom, Saskia; Christensen, James G.; Chao, Richard; Bauer, Todd Share Save
Targeting multiple receptor tyrosine kinases with sitravatinib: A Phase 1b study in advanced renal cell carcinoma and castrate-resistant prostate cancer Pant, Shubham; Cho, Byoung Chul; Kyriakopoulos, Christos E.; Spira, Alexander; Tannir, Nizar; Werner, Theresa L.; Yan, Xiaohong; Neuteboom, Saskia; Chao, Richard; Goel, Sanjay Share Save
KRYSTAL-7: Efficacy and safety of adagrasib with pembrolizumab in patients with treatment-naive, advanced non-small cell lung cancer (NSCLC) harboring a KRASG12C mutation Garassino, M. C.; Theelen, W. S. M. E.; Jotte, R.; Laskin, J.; De Marinis, F.; Aguado, C.; Badin, F. B.; Chmielewska, I.; Hochmair, M. J.; Lu, S.; Nadal, E.; Ostoros, G.; Felip, E.; Spira, A. I.; Lane, C. M.; He, J.; Chao, R.; Janne, P. A. Share Save
Early Changes in Circulating Cell-Free KRAS G12C Predict Response to Adagrasib in KRAS Mutant Non-Small Cell Lung Cancer Patients Paweletz, Cloud P.; Heavey, Grace A.; Kuang, Yanan; Durlacher, Emily; Kheoh, Thian; Chao, Richard C.; Spira, Alexander I.; Leventakos, Konstantinos; Johnson, Melissa L.; Ou, Sai-Hong Ignatius; Riely, Gregory J.; Anderes, Kenna; Yang, Wenjing; Christensen, James G.; Janne, Pasi A. Share Save
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Phase I Study Evaluating Glesatinib (MGCD265), An Inhibitor of MET and AXL, in Patients with Non-small Cell Lung Cancer and Other Advanced Solid Tumors Kollmannsberger, Christian; Hurwitz, Herbert; Bazhenova, Lyudmila; Cho, Byoung Chul; Hong, David; Park, Keunchil; Reckamp, Karen L.; Sharma, Sunil; Der-Torossian, Hirak; Christensen, James G.; Faltaos, Demiana; Potvin, Diane; Tassell, Vanessa; Chao, Richard; Shapiro, Geoffrey, I Share Save
Adagrasib in Non-Small-Cell Lung Cancer Harboring a KRASG12C Mutation Jaenne, Pasi A.; Riely, Gregory J.; Gadgeel, Shirish M.; Heist, Rebecca S.; Ou, Sai-Hong I.; Pacheco, Jose M.; Johnson, Melissa L.; Sabari, Joshua K.; Leventakos, Konstantinos; Yau, Edwin; Bazhenova, Lyudmila; Negrao, Marcelo V.; Pennell, Nathan A.; Zhang, Jun; Anderes, Kenna; Der-Torossian, Hirak; Kheoh, Thian; Velastegui, Karen; Yan, Xiaohong; Christensen, James G.; Chao, Richard C.; Spira, Alexander I. Share Save
First-in-human phase 1/1b study to evaluate sitravatinib in patients with advanced solid tumors Bauer, Todd; Cho, Byong Chul; Heist, Rebecca; Bazhenova, Lyudmila; Werner, Theresa; Goel, Sanjay; Kim, Dong-Wan; Adkins, Douglas; Carvajal, Richard D.; Alva, Ajjai; Eaton, Keith; Wang, Judy; Liu, Yong; Yan, Xiaohong; Christensen, Jamie; Neuteboom, Saskia; Chao, Richard; Pant, Shubham Share Save
Phase I Study of Glesatinib (MGCD265) in Combination with Erlotinib or Docetaxel in Patients with Advanced Solid Tumors (vol 17, pg 125, 2022) Patnaik, Amita; Gadgeel, Shirish; Papadopoulos, Kyriakos P.; Rasco, Drew W.; Haas, Naomi B.; Der-Torossian, Hirak; Faltaos, Demiana; Potvin, Diane; Tassell, Vanessa; Tawashi, Manal; Chao, Richard; O'Dwyer, Peter J. Share Save
Phase I Study of Glesatinib (MGCD265) in Combination with Erlotinib or Docetaxel in Patients with Advanced Solid Tumors Patnaik, Amita; Gadgeel, Shirish; Papadopoulos, Kyriakos P.; Rasco, Drew W.; Haas, Naomi B.; Der-Torossian, Hirak; Faltaos, Demiana; Potvin, Diane; Tassell, Vanessa; Tawashi, Manal; Chao, Richard; O'Dwyer, Peter J. Share Save
The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients Hallin, Jill; Engstrom, Lars D.; Hargis, Lauren; Calinisan, Andrew; Aranda, Ruth; Briere, David M.; Sudhakar, Niranjan; Bowcut, Vickie; Baer, Brian R.; Ballard, Joshua A.; Burkard, Michael R.; Fell, Jay B.; Fischer, John P.; Vigers, Guy P.; Xue, Yaohua; Gatto, Sole; Fernandez-Banet, Julio; Pavlicek, Adam; Velastagui, Karen; Chao, Richard C.; Barton, Jeremy; Pierobon, Mariaelena; Baldelli, Elisa; Patricoin, Emanuel F., III; Cassidy, Douglas P.; Marx, Matthew A.; Rybkin, Igor I.; Johnson, Melissa L.; Ou, Sai-Hong Ignatius; Lito, Piro; Papadopoulos, Kyriakos P.; Janne, Pasi A.; Olson, Peter; Christensen, James G. Share Save
Phase II study of sunitinib in Japanese patients with unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumor (vol 31, pg 1265, 2013) Ito, Tetsuhide; Okusaka, Takuji; Nishida, Toshirou; Yamao, Kenji; Igarashi, Hisato; Morizane, Chigusa; Kondo, Shunsuke; Mizuno, Nobumasa; Hara, Kazuo; Sawaki, Akira; Hashigaki, Satoshi; Kimura, Nobuyuki; Murakami, Mami; Ohki, Emiko; Chao, Richard C.; Imamura, Masayuki Share Save
Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes Grivas, Petros; Mortazavi, Amir; Picus, Joel; Hahn, Noah M.; Milowsky, Matthew, I; Hart, Lowell L.; Alva, Ajjai; Bellmunt, Joaquim; Pal, Sumanta K.; Bambury, Richard M.; O'donnell, Peter H.; Gupta, Sumati; Guancial, Elizabeth A.; Sonpavde, Guru P.; Faltaos, Demiana; Potvin, Diane; Christensen, James G.; Chao, Richard C.; Rosenberg, Jonathan E. Share Save
Patient-Reported Outcomes and Quality of Life with Sunitinib Versus Placebo for Pancreatic Neuroendocrine Tumors: Results From an International Phase III Trial Vinik, Aaron; Bottomley, Andrew; Korytowsky, Beata; Bang, Yung-Jue; Raoul, Jean-Luc; Valle, Juan W.; Metrakos, Peter; Hoersch, Dieter; Mundayat, Rajiv; Reisman, Arlene; Wang, Zhixiao; Chao, Richard C.; Raymond, Eric Share Save
f Institutional implementation of clinical tumor profiling on an unselected cancer population Sholl, Lynette M.; Do, Khanh; Shivdasani, Priyanka; Cerami, Ethan; Dubuc, Adrian M.; Kuo, Frank C.; Garcia, Elizabeth P.; Jia, Yonghui; Davineni, Phani; Abo, Ryan P.; Pugh, Trevor J.; van Hummelen, Paul; Thorner, Aaron R.; Ducar, Matthew; Berger, Alice H.; Nishino, Mizuki; Janeway, Katherine A.; Church, Alanna; Harris, Marian; Ritterhouse, Lauren L.; Campbell, Joshua D.; Rojas-Rudilla, Vanesa; Ligon, Azra H.; Ramkissoon, Shakti; Cleary, James M.; Matulonis, Ursula; Oxnard, Geoffrey R.; Chao, Richard; Tassell, Vanessa; Christensen, James; Hahn, William C.; Kantoff, Philip W.; Kwiatkowski, David J.; Johnson, Bruce E.; Meyerson, Matthew; Garraway, Levi A.; Shapiro, Geoffrey I.; Rollins, Barrett J.; Lindeman, Neal I.; MacConaill, Laura E. Share Save
Amethyst NSCLC trial: Phase 2, parallel-arm study of receptor tyrosine kinase (RTK) inhibitor, MGCD265 in patients with advanced or metastatic non-small cell lung cancer (NSCLC) with activating genetic alterations in mesenchymal-epithelial transition factor (MET) Bazhenova, L.; Mehra, R.; Nagy, T.; Cavanna, L.; Lee, J-S.; Han, J-Y.; Kim, H. K.; Halmos, B.; Shum, M.; Schreeder, M.; Rybkin, I.; Badin, F.; Mena, R.; Janne, P. A.; Christensen, J.; Tassell, V.; Chao, R.; Faltaos, D.; Kim, D-W. Share Save
A first-in-human phase 1/1b study of receptor tyrosine kinase (RTK) inhibitor, MGCD516, in patients with advanced solid tumors Schwartz, G.; Adkins, D.; Heist, R.; Werner, T.; Abbott, M.; Barber, S.; Slusarz, K.; Agarwal, N.; Neuteboom, S.; Faltaos, D.; Chen, I.; Christensen, J.; Chao, R.; Bauer, T. Share Save
Phase II study of sunitinib in Japanese patients with unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumor Ito, Tetsuhide; Okusaka, Takuji; Nishida, Toshirou; Yamao, Kenji; Igarashi, Hisato; Morizane, Chigusa; Kondo, Shunsuke; Mizuno, Nobumasa; Hara, Kazuo; Sawaki, Akira; Hashigaki, Satoshi; Kimura, Nobuyuki; Murakami, Mami; Ohki, Emiko; Chao, Richard C.; Imamura, Masayuki Share Save
A randomized, double-blind, phase II study of erlotinib with or without sunitinib for the second-line treatment of metastatic non-small-cell lung cancer (NSCLC) Groen, H. J. M.; Socinski, M. A.; Grossi, F.; Juhasz, E.; Gridelli, C.; Baas, P.; Butts, C. A.; Chmielowska, E.; Usari, T.; Selaru, P.; Harmon, C.; Williams, J. A.; Gao, F.; Tye, L.; Chao, R. C.; Blumenschein, G. R. Share Save
Sunitinib combined with pemetrexed and carboplatin in patients with advanced solid malignancies-results of a phase I dose-escalation study Blais, Normand; Camidge, D. Ross; Jonker, Derek J.; Soulieres, Denis; Laurie, Scott A.; Diab, Sami G.; Ruiz-Garcia, Ana; Thall, Aron; Zhang, Ke; Chao, Richard C.; Chow, Laura Q. Share Save