Kadir C. Akdemir - Publications, H-index & Citations

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Kadir C. Akdemir

The University of Texas MD Anderson Cancer Center

44H-index

200Paper Count

2.3WCitation Count

Published Papers 42

Publication Date

Author Correction: Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer

Nature

IF48.5

2026-08-17

PREAI

Giannicola Genovese; Alessandro Carugo; James Tepper; Frederick Scott Robinson; Liren Li; Maria Svelto; Luigi Nezi; Denise Corti; Rosalba Minelli; Piergiorgio Pettazzoni; Tony Gutschner; Chia-Chin Wu; Sahil Seth; Kadir Caner Akdemir; Elisabetta Leo; Samirkumar Amin; Marco Dal Molin; Haoqiang Ying; Lawrence N. Kwong; Simona Colla; Koichi Takahashi; Papia Ghosh; Virginia Giuliani; Florian Muller; Prasenjit Dey; Shan Jiang; Jill Garvey; Chang-Gong Liu; Jianhua Zhang; Timothy P. Heffernan; Carlo Toniatti; Jason B. Fleming; Michael G. Goggins; Laura D. Wood; Alessandro Sgambato; Abbas Agaimy; Anirban Maitra; Charles W. M. Roberts; Huamin Wang; Andrea Viale; Ronald A. DePinho; Giulio F. Draetta; Lynda Chin

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Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS–chemokine–myeloid axis

Science Advances

IF12.5

2026-03-11

OAAI

Bruno Beernaert; Rose L. Jady-Clark; Parin Shah; Erik Ramon-Gil; Nora M. Lawson; Zack D. Brodtman; Somnath Tagore; Frederik Stihler; Alfie S. Carter; Shannique Clarke; Tong Liu; Winston M. Zhu; Juliet E. Martin; Erkin Erdal; Alistair Easton; Leticia Campo; Molly Browne; Stephen Ash; Rabial Q. Raja; Nicola Waddell; Tom Crosby; Simon R. Lord; Derek A. Mann; Ignacio Melero; Carlos E. de Andrea; Andréa E. Tijhuis; Floris Foijer; Ester M. Hammond; Kadir C. Akdemir; Jack Leslie; Benjamin Izar; Eileen E. Parkes

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Dual phagocytosis-checkpoint blockade revitalizes immune surveillance in mouse models of glioblastoma

Nature Communications

IF15.7

2026-03-09

OAAI

JongHoon Ha; Yifan Wang; Yifan Ma; Annette Wu; Shiyan Dong; Seong Dong Jeong; Jared L. Edwards; Mengyu Chang; Yen-Tzu Chang; Xiaotian Wang; Maurice Dufilho; Michelle Najarro Torres; Shannon McCabe; Weiye Deng; Adam J. Grippin; Jeffrey S. Weinberg; Shaan M. Raza; Franco DeMonte; Ian E. McCutcheon; Sujit Prabhu; Sherise D. Ferguson; Chibawanye I. Ene; Kadir Akdemir; Sreyashi Basu; Sonali Jindal; Benjamin R. Schrank; Jian Hu; Sangeeta Goswami; Vinay K. Puduvalli; Frederick F. Lang; Kristin Huntoon; Padmanee Sharma; Betty Y. S. Kim; Wen Jiang

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Loss of KDM6A-mediated genomic instability and metabolic reprogramming regulates response to therapeutic perturbations in bladder cancer

Nature Communications

IF15.7

2026-01-07

OAAI

Pratishtha Singh; Ranit D’Rozario; Bidisha Chakraborty; Swadhin Meher; Deblina Raychaudhuri; Aminah J. Tannir; Yang Li; Anurag Majumdar; Jessalyn Hawkins; Yun Xiong; Philip Lorenzi; Padmanee Sharma; Kadir Akdemir; Patrick Pilie; Abhinav K. Jain; Byron Hing Lung Lee; Sangeeta Goswami

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Single cell spatial profiling of the matrisome identifies region-specific adhesion and signaling networks in glioblastoma

Communications Biology

IF5.1

2025-12-09

OAAI

Arpan De; Santiago A. Forero; Ali Pirani; John E. Morales; Marisol De La Fuente-Granada; Sumod Sebastian; Jason T. Huse; Leomar Y. Ballester; Jeffrey S. Weinberg; Frederick F. Lang; Kadir C. Akdemir; Joseph H. McCarty

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Multimodal spatial-omics reveal co-evolution of alveolar progenitors and proinflammatory niches in progression of lung precursor lesions

Cancer Cell

IF44.5

2025-11-06

OAAI

Fuduan Peng; Ansam Sinjab; Yibo Dai; Warapen Treekitkarnmongkol; Sujuan Yang; Lorena I. Gomez Bolanos; Tieling Zhou; Minyue Chen; Alejandra G. Serrano; Avantika Krishna; Nastaran Karimi; Manvi Sharma; Akshay Basi; Guangsheng Pei; Jianlong Liao; Yunhe Liu; Jiping Feng; Zahraa Rahal; Yang Liu; Jiahui Jiang; Kai Yu; Tala Noun; Yuejiang Liu; Khaja Khan; Kyung Serk Cho; Jichao Chen; Luisa M. Solis; Sarah Mazzilli; Steven Dubinett; Tina Cascone; Avrum E. Spira; Stephen Swisher; Naoe Jimbo; Takuo Hayashi; Satsuki Kishikawa; Kazuya Takamochi; Tomoo Itoh; Takashi Yao; Kenji Suzuki; Neda Kalhor; Ignacio I. Wistuba; Mingyao Li; Seyed Javad Moghaddam; Junya Fujimoto; Jared Burks; Jeffrey Myers; Kadir Akdemir; Linghua Wang; Humam Kadara

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The oncolytic adenovirus Delta-24-RGD achieves antitumor polarization of the chordoma tumor microenvironment in human and murine models of chordoma

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Wu, Xizi; Ledbetter, Daniel; Wang, Wein-Lien; Singh, Sanjay; Gumin, Joy; Fan, Xuejun; Gillard, Andrew; Shin, Dong Ho; Jiang, Hong; Zhao, Bo; Akdemir, Kadir; Conley, Anthony; Lazar, Alexander; Tatsui, Claudio; Lang, Frederick; Gomez-Manzano, Candelaria; Fueyo, Juan; Rhines, Laurence; Alvarez-Breckenridge, Christopher

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Extra-central nervous system metastasis from high-grade glioma: a single-institution experience

JOURNAL OF NEURO-ONCOLOGY

IF3.1

2025-03-01

PREAI

Faraj, Christina Abi; Mccutcheon, Ian E.; Gubbiotti, Maria A.; Perni, Subha; Gule-Monroe, Maria K.; Akdemir, Kadir; Clark, Victoria E.; Bander, Evan D.; Loghin, Monica E.; Prabhu, Sujit S.; Lang, Frederick F.; Weinberg, Jeffrey S.

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INVESTIGATING EGFR CONTAINING EXTRACHROMOSOMAL DNA DYNAMICS IN GBM

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Zhao, Bo; Cho, Chae Yun; Ye, Lingqun; Akdemir, Kadir

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CONCURRENT AMPLIFICATION OF TBXT AND HIGHLY ACTIVATED ENHANCERS IN EXTRACHROMOSOMAL DNA (ECDNA) DRIVES CHORDOMA TUMORIGENESIS

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Zhao, Bo; Ines, Martin Barrio; Ye, Lingqun; Wu, Xizi; Soragni, Alice; Futreal, Andrew; Akdemir, Kadir

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Investigating oncogene amplifications in brain metastasis of esophageal adenocarcinoma samples

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Lawson, Nora; Ye, Lingqun; Zhao, Bo; Futreal, Andy; Akdemir, Kadir

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Transcriptional analysis of immune microenvironment of chordomas of the skull base and mobile spine

ANNALS OF ONCOLOGY

IF65.4

2023-10-01

OAAI

Roszik, J.; Alvarez-Breckenridge, C.; Akdemir, K. C.; Bird, J.; Patel, S.; Lazar, A.; Wang, W-L.; Ghia, A.; Grosshans, D.; Bishop, A.; Tatsui, C.; Demonte, F.; Rhines, L.; Yee, C.; Patel, S.; Raza, S.; Conley, A. P.

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Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer (vol 52, pg 294, 2020)

NATURE GENETICS

IF31.8

2023-03-21

OAAI

Akdemir, Kadir C.; Le, Victoria T.; Chandran, Sahaana; Li, Yilong; Verhaak, Roel G.; Beroukhim, Rameen; Campbell, Peter J.; Chin, Lynda; Dixon, Jesse R.; Futreal, P. Andrew

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Ubp8 and SAGA Regulate Snf1 AMP Kinase Activity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Wilson, Marenda A.; Koutelou, Evangelia; Hirsch, Calley; Akdemir, Kadir; Schibler, Andria; Barton, Michelle Craig; Dent, Sharon Y. R.

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Pan-cancer landscape of AID-related mutations, composite mutations, and their potential role in the ICI response

NPJ PRECISION ONCOLOGY

IF8

2022-12-01

OAAI

Hernandez-Verdin, Isaias; Akdemir, Kadir C.; Ramazzotti, Daniele; Caravagna, Giulio; Labreche, Karim; Mokhtari, Karima; Hoang-Xuan, Khe; Peyre, Matthieu; Bielle, Franck; Touat, Mehdi; Idbaih, Ahmed; Duval, Alex; Sanson, Marc; Alentorn, Agusti

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Prognostic molecular biomarkers in chordomas: A systematic review and identification of clinically usable biomarker panels

FRONTIERS IN ONCOLOGY

IF3.3

2022-09-29

OAAI

Rubino, Franco; Alvarez-Breckenridge, Christopher; Akdemir, Kadir; Conley, Anthony P.; Bishop, Andrew J.; Wang, Wei-Lien; Lazar, Alexander J.; Rhines, Laurence D.; DeMonte, Franco; Raza, Shaan M.

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Immune Checkpoint Inhibitors Have Clinical Activity in Patients With Recurrent Chordoma

JOURNAL OF IMMUNOTHERAPY

IF2.9

2022-08-04

OAAI

Bishop, Andrew J.; Amini, Behrang; Lin, Heather; Raza, Shaan M.; Patel, Shreyaskumar; Grosshans, David R.; Ghia, Amol; Farooqi, Ahsan; Guadagnolo, B. Ashleigh; Mitra, Devarati; Akdemir, Kadir C.; Lazar, Alexander J.; Wang, Wei-Lien; Alvarez-Breckenridge, Christopher; Bird, Justin; Rhines, Laurence D.; Somaiah, Neeta; Conley, Anthony P.

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Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer

GASTROENTEROLOGY

IF25.1

2021-07-01

OAAI

Inoue, Akira; Robinson, Frederick S.; Minelli, Rosalba; Tomihara, Hideo; Rizi, Bahar Salimian; Rose, Johnathon L.; Kodama, Takahiro; Srinivasan, Sanjana; Harris, Angela L.; Zuniga, Andy M.; Mullinax, Robert A.; Ma, Xiaoyan; Seth, Sahil; Daniele, Joseph R.; Peoples, Michael D.; Loponte, Sara; Akdemir, Kadir C.; Khor, Tin Oo; Feng, Ningping; Roszik, Jason; Sobieski, Mary M.; Brunell, David; Stephan, Clifford; Giuliani, Virginia; Deem, Angela K.; Shingu, Takashi; Deribe, Yonathan Lissanu; Menter, David G.; Heffernan, Timothy P.; Viale, Andrea; Bristow, Christopher A.; Kopetz, Scott; Draetta, Giulio F.; Genovese, Giannicola; Carugo, Alessandro

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Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations

NUCLEIC ACIDS RESEARCH

IF13.1

2021-04-20

OAAI

Yang, Jie; Horton, John R.; Akdemir, Kadir C.; Li, Jia; Huang, Yun; Kumar, Janani; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

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Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure

NATURE GENETICS

IF31.8

2020-10-05

OAAI

Akdemir, Kadir C.; Le, Victoria T.; Kim, Justin M.; Killcoyne, Sarah; King, Devin A.; Lin, Ya-Ping; Tian, Yanyan; Inoue, Akira; Amin, Samirkumar B.; Robinson, Frederick S.; Nimmakayalu, Manjunath; Herrera, Rafael E.; Lynn, Erica J.; Chan, Kin; Seth, Sahil; Klimczak, Leszek J.; Gerstung, Moritz; Gordenin, Dmitry A.; O'Brien, John; Li, Lei; Deribe, Yonathan Lissanu; Verhaak, Roel G.; Campbell, Peter J.; Fitzgerald, Rebecca; Morrison, Ashby J.; Dixon, Jesse R.; Andrew Futreal, P.

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Research Directions