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Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E mutated colorectal cancer-results from the FIRE-4.5 study Klein-Scory, Susanne; Baraniskin, Alexander; Schmiegel, Wolff; Mika, Thomas; Schroers, Roland; Held, Swantje; Heinrich, Kathrin; Tougeron, David; Modest, Dominik P.; Schwaner, Ingo; Eucker, Jan; Pihusch, Rudolf; Stauch, Martina; Kaiser, Florian; Kahl, Christoph; Karthaus, Meinolf; Mueller, Christian; Burkart, Christof; Stintzing, Sebastian; Heinemann, Volker Share Save
Prognostic and predictive value of CA 19-9 in locally advanced pancreatic cancer treated with multiagent induction chemotherapy: results from a prospective, multicenter phase II trial (NEOLAP-AIO-PAK-0113) (vol 7, 100552, 2024) Hartlapp, I.; Valta-Seufzer, D.; Siveke, J. T.; Alguel, H.; Goekkurt, E.; Siegler, G.; Martens, U. M.; Waldschmidt, D.; Pelzer, U.; Fuchs, M.; Kullmann, F.; Boeck, S.; Ettrich, T. J.; Held, S.; Keller, R.; Anger, F.; Germer, C. T.; Stang, A.; Kimmel, B.; Heinemann, V.; Kunzmann, V. Share Save
Alternating gemcitabine plus nab-paclitaxel and gemcitabine alone versus continuous gemcitabine plus nab-paclitaxel after induction treatment of metastatic pancreatic cancer (ALPACA): a multicentre, randomised, open-label, phase 2 trial Dorman, Klara; Boeck, Stefan; Caca, Karel; Reichert, Maximilian; Ettrich, Thomas J.; Oettle, Helmut; Waidmann, Oliver; Modest, Dominik P.; Mueller, Lothar; Michl, Patrick; Kanzler, Stephan; Pink, Daniel; Reinacher-Schick, Anke; Geissler, Michael; Pelz, Henning; Kunzmann, Volker; Held, Swantje; Schichtl, Thomas; Heinemann, Volker; Kullmann, Frank Share Save
Impact of primary tumor sidedness and sex on prognosis and anti-epidermal growth factor receptor antibody efficacy in BRAF-mutant metastatic colorectal cancer: a pooled analysis of AIO studies FIRE-1, CIOX, FIRE-3, XELAVIRI, and VOLFI Alig, A. H. S.; Modest, D. P.; Stintzing, S.; Heinrich, K.; Geissler, M.; von Weikersthal, L. Fischer; Decker, T.; Vehling-Kaiser, U.; Held, S.; Moosmann, N.; Stahler, A.; Tannapfel, A.; Giessen-Jung, C.; Jung, A.; Weiss, L.; Heinemann, V. Share Save
Subgroup analyses from patients with pre-treated metastatic colorectal cancer receiving trifluridine/tipiracil: results of the TALLISUR trial Karthaus, Meinolf; Heinemann, Volker; Riera-Knorrenschild, Jorge; Kretzschmar, Albrecht; Welslau, Manfred; Kaiser, Ulrich; Pelz, Henning; Ettrich, Thomas J.; Held, Swantje; Kehmann, Linde; Hess, Juergen; Reislaender, Timo; Weiss, Lena Share Save
Dermatology-related quality-of-life outcomes in patients with RAS wild-type metastatic colorectal cancer treated with fluorouracil and folinic acid with or without panitumumab (Pmab) maintenance after FOLFOX D Pmab induction: a prespecified secondary analysis of the phase II randomized PanaMa (AIO KRK 0212) trial Ballhausen, A.; Karthaus, M.; Fruehauf, S.; Graeven, U.; Mueller, L.; Koenig, A. O.; von Weikersthal, L. F.; Sommerhaeuser, G.; Jelas, I.; Alig, A. H. S.; Kurreck, A.; Stahler, A.; Goekkurt, E.; Held, S.; Kasper, S.; Heinrich, K.; Heinemann, V.; Stintzing, S.; Trarbach, T.; Modest, D. P. Share Save
Gemcitabine and nab-paclitaxel combined with afatinib in metastatic pancreatic cancer - Results of a phase 1b clinical trial Zhang, Danmei; Westphalen, C. Benedikt; Quante, Michael; Waldschmidt, Dirk T.; Held, Swantje; Kuetting, Fabian; Dorman, Klara; Heinrich, Kathrin; Weiss, Lena; Boukovala, Myrto; Haas, Michael; Boeck, Stefan; Heinemann, Volker; Probst, Victoria Share Save
Prognostic and predictive impact of metastatic organ involvement on maintenance therapy in advanced metastatic colorectal cancer: Subgroup analysis of patients treated within the PanaMa trial (AIO KRK 0212) Sommerhaeuser, Greta; Karthaus, Meinolf; Kurreck, Annika; Ballhausen, Alexej; Meyer-Knees, Johanna W.; Fruehauf, Stefan; Graeven, Ullrich; Mueller, Lothar; Koenig, Alexander O.; Weikersthal, Ludwig Fischer V.; Goekkurt, Eray; Haas, Siegfried; Stahler, Arndt; Heinemann, Volker; Held, Swantje; Alig, Annabel H. S.; Kasper-Virchow, Stefan; Stintzing, Sebastian; Trarbach, Tanja; Modest, Dominik P. Share Save
The systemic proteome of consensus molecular subtypes from patients with RAS wild-type metastatic colorectal cancer: Analysis from the randomized phase II PanaMa (AIO KRK0212) trial Ballhausen, A.; Shomroni, O.; Stahler, A.; Hoppe, B.; Karthaus, M.; Fruehauf, S.; Graeven, U.; Sommerhaeuser, G. M.; Alig, A. H. S.; Goekkurt, E.; Meyer-Knees, J.; Kurreck, A.; Held, S.; Kasper-Virchow, S.; Heinemann, V.; Stintzing, S.; Trarbach, T.; Mulleder, M.; Ralser, M.; Modest, D. P. Share Save
Health-related quality of life in patients with RAS wild- type metastatic colorectal cancer treated with fluorouracil and folinic acid with or without panitumumab as maintenance therapy: a prespecified secondary analysis of the PanaMa (AIO KRK 0212) trial Ballhausen, Alexej; Karthaus, Meinolf; Fruehauf, Stefan; Graeven, Ullrich; Mueller, Lothar; Koenig, Alexander Otto; von Weikersthal, Ludwig Fischer; Sommerhaeuser, Greta; Alig, Annabel Helga Sophie; Goekkurt, Eray; Meyer-Knees, Johanna Wanda; Kurreck, Annika; Stahler, Arndt; Held, Swantje; Kasper, Stefan; Heinrich, Kathrin; Heinemann, Volker; Stintzing, Sebastian; Trarbach, Tanja; Modest, Dominik Paul Share Save
Impact of sex on the efficacy and safety of panitumumab plus fluorouracil and folinic acid versus fluorouracil and folinic acid alone as maintenance therapy in RAS WT metastatic colorectal cancer (mCRC). Subgroup analysis of the PanaMa-study (AIO-KRK-0212)* Heinrich, K.; Karthaus, M.; Fruehauf, S.; Graeven, U.; Mueller, L.; Koenig, A. O.; von Weikersthal, L. Fischer; Caca, K.; Kretzschmar, A.; Goekkurt, E.; Haas, S.; Alig, A. H. S.; Kurreck, A.; Stahler, A.; Held, S.; Sommerhaeuser, G.; Heinemann, V.; Stintzing, S.; Trarbach, T.; Modest, D. P. Share Save
Prognostic and predictive value of CEA before initiation of therapy in the XELAVIRI trial Alig, A.; Heinemann, V.; von Weikersthal, L. Fischer; Decker, T.; Vehling-Kaiser, U.; Uhlig, J.; Schenk, M.; Denzlinger, C.; Stahler, A.; Held, S.; Stintzing, S.; Modest, D.; Heinrich, K. Share Save
Predictive value of computed tomography on surgical resectability in locally advanced pancreatic cancer treated with multiagent induction chemotherapy: Results from a prospective, multicentre phase 2 trial (NEOLAP-AIO-PAK-0113) Guggenberger, KV.; Bley, TA.; Held, S.; Keller, R.; Flemming, S.; Wiegering, A.; Germer, CT.; Kimmel, B.; Kunzmann, V.; Hartlapp, I.; Anger, F. Share Save
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212) Sommerhauser, Greta; Kurreck, Annika; Beck, Alexander; Fehrenbach, Uli; Karthaus, Meinolf; Fruehauf, Stefan; Graeven, Ullrich; Mueller, Lothar; Koenig, Alexander O.; Weikersthal, Ludwig F. v.; Goekkurt, Eray; Haas, Siegfried; Stahler, Arndt; Heinemann, Volker; Held, Swantje; Alig, Annabel H. S.; Kasper, Stefan; Stintzing, Sebastian; Trarbach, Tanja; Modest, Dominik P. Share Save
First-line fluoropyrimidine plus bevacizumab followed by irinotecan-escalation versus initial fluoropyrimidine, irinotecan and bevacizumab in patients with metastatic colorectal cancer - Final survival and per-protocol analysis of the randomised XELAVIRI trial (AIO KRK 0110) Stahler, Arndt; Modest, Dominik P.; von Weikersthal, Ludwig Fischer; Kaiser, Florian; Decker, Thomas; Held, Swantje; Graeven, Ullrich; Schwaner, Ingo; Denzlinger, Claudio; Schenk, Michael; Kurreck, Annika; Heinrich, Kathrin; Giessen-Jung, Clemens; Neumann, Jens; Kirchner, Thomas; Jung, Andreas; Stintzing, Sebastian; Heinemann, Volker Share Save
FOLFOX plus panitumumab or FOLFOX alone as additive therapy following R0/1 resection of RAS wild-type colorectal cancer liver metastases - The PARLIM trial (AIO KRK 0314) Modest, Dominik Paul; Karthaus, Meinolf; Kasper, Stefan; Moosmann, Nicolas; Keitel, Verena; Kiani, Alexander; Uhlig, Jens; Jacobasch, Lutz; Weikersthal, Ludwig Fischer, V; Fuchs, Martin; Kaiser, Florian; Lerchenmueller, Christian; Sent, Dagmar; Junghanss, Christian; Held, Swantje; Lorenzen, Sylvie; Kaczirek, Klaus; Jung, Andreas; Stintzing, Sebastian; Heinemann, Volker Share Save
Impact of depth of response of induction therapy on consecutive maintenance therapy in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212) Sommerhaeser, G. M.; Kurreck, A.; Fehrenbach, U.; Beck, A.; Karthaus, M.; Fruehauf, S.; Graeven, U.; Mueller, L.; Koenig, A. O.; Von Weikersthal, L. Fischer; Goekkurt, E.; Haas, S.; Stahler, A.; Heinemann, V.; Held, S.; Alig, A. H. S.; Kasper, S.; Stintzing, S.; Trarbach, T.; Modest, D. P. Share Save
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