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Using gene-environment interactions to explore pathways for colorectal cancer risk Bouras, Emmanouil; Yu, Ren; Kim, Andre E.; Markozannes, Georgios; Murphy, Neil; Albanes, Demetrius; Anderson, Laura N.; Barry, Elizabeth L.; Berndt, Sonja I.; Bishop, D. Timothy; Brenner, Hermann; Burnett-Hartman, Andrea; Campbell, Peter T.; Carreras-Torres, Robert; Chan, Andrew T.; Cheng, Iona; Devall, Matthew A.; Diez-Obrero, Virginia; Dimou, Niki; Drew, David A.; Gruber, Stephen B.; Gsur, Andrea; Hoffmeister, Michael; Hsu, Li; Huyghe, Jeroen R.; Kawaguchi, Eric; Keku, Temitope O.; Kundaje, Anshul; Kury, Sebastien; Le Marchand, Loic; Lewinger, Juan Pablo; Li, Li; Lynch, Brigid M.; Moreno, Victor; Morrison, John L.; Newton, Christina C.; Obon-Santacana, Mireia; Palmer, Julie R.; Papadimitriou, Nikos; Pellatt, Andrew J.; Peoples, Anita R.; Pharoah, Paul D. P.; Platz, Elizabeth A.; Qu, Conghui; Ruiz-Narvaez, Edward; Mendez, Joel Sanchez; Schoen, Robert E.; Stern, Mariana C.; Thomas, Claire E.; Tian, Yu; Um, Caroline Y.; Visvanathan, Kala; Vodicka, Pavel; Vymetalkova, Veronika; White, Emily; Wolk, Alicja; Woods, Michael O.; Wu, Anna H.; Gunter, Marc J.; Gauderman, W. James; Peters, Ulrike; Evangelou, Marina; Tsilidis, Konstantinos K. Share Save
Transcriptome-wide Mendelian randomization exploring dynamic CD4+T cell gene expression in colorectal cancer development Deslandes, Benedita; Wu, Xueyan; Lee, Matthew A.; Goudswaard, Lucy J.; Jones, Gareth W.; Gsur, Andrea; Lindblom, Annika; Ogino, Shuji; Vymetalkova, Veronika; Wolk, Alicja; Wu, Anna H.; Huyghe, Jeroen R.; Peters, Ulrike; Phipps, Amanda, I; Thomas, Claire E.; Pai, Rish K.; Grant, Robert C.; Buchanan, Daniel D.; Yarmolinsky, James; Gunter, Marc J.; Zheng, Jie; Hazelwood, Emma; Vincent, Emma E. Share Save
Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis Hazelwood, Emma; Goudswaard, Lucy J.; Lee, Matthew A.; Vabistsevits, Marina; Pournaras, Dimitri J.; Brenner, Hermann; Buchanan, Daniel D.; Gruber, Stephen B.; Gsur, Andrea; Li, Li; Vodickova, Ludmila; Grant, Robert C.; Samadder, N. Jewel; Timpson, Nicholas J.; Gunter, Marc J.; Schuster-Bockler, Benjamin; Yarmolinsky, James; Richardson, Tom G.; Freisling, Heinz; Murphy, Neil; Vincent, Emma E. Share Save
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Circulating tryptophan-kynurenine pathway metabolites are associated with all-cause mortality among patients with stage I-III colorectal cancer Damerell, Victoria; Klaassen-Dekker, Niels; Brezina, Stefanie; Ose, Jennifer; Ulvik, Arve; van Roekel, Eline H.; Holowatyj, Andreana N.; Baierl, Andreas; Bohm, Juergen; Bours, Martijn J. L.; Brenner, Hermann; de Wilt, Johannes H. W.; Grady, William M.; Habermann, Nina; Hoffmeister, Michael; Keski-Rahkonen, Pekka; Lin, Tengda; Schirmacher, Peter; Schrotz-King, Petra; Ulrich, Alexis B.; van Duijnhoven, Franzel J. B.; Warby, Christy A.; Shibata, David; Toriola, Adetunji T.; Figueiredo, Jane C.; Siegel, Erin M.; Li, Christopher I.; Gsur, Andrea; Kampman, Ellen; Schneider, Martin; Ueland, Per M.; Weijenberg, Matty P.; Ulrich, Cornelia M.; Kok, Dieuwertje E.; Gigic, Biljana Share Save
Genome-wide association studies and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer Laskar, R. S.; Qu, C.; Huyghe, J. R.; Harrison, T.; Hayes, R. B.; Cao, Y.; Campbell, P. T.; Steinfelder, R.; Talukdar, F. R.; Brenner, H.; Ogino, S.; Brendt, S.; Bishop, D. T.; Buchanan, D. D.; Chan, A. T.; Cotterchio, M.; Gruber, S. B.; Gsur, A.; van Guelpen, B.; Jenkins, M. A.; Keku, T. O.; Lynch, B. M.; Le Marchand, L.; Martin, R. M.; McCarthy, K.; Moreno, V.; Pearlman, R.; Song, M.; Tsilidis, K. K.; Vodicka, P.; Woods, M. O.; Wu, K.; Hsu, L.; Gunter, M. J.; Peters, U.; Murphy, N. Share Save
Two genome-wide interaction loci modify the association of nonsteroidal anti-inflammatory drugs with colorectal cancer Drew, David A.; Kim, Andre E.; Lin, Yi; Qu, Conghui; Morrison, John; Lewinger, Juan Pablo; Kawaguchi, Eric; Wang, Jun; Fu, Yubo; Zemlianskaia, Natalia; Diez-Obrero, Virginia; Bien, Stephanie A.; Dimou, Niki; Albanes, Demetrius; Baurley, James W.; Wu, Anna H.; Buchanan, Daniel D.; Potter, John D.; Prentice, Ross L.; Harlid, Sophia; Arndt, Volker; Barry, Elizabeth L.; Berndt, Sonja I.; Bouras, Emmanouil; Brenner, Hermann; Budiarto, Arif; Burnett-Hartman, Andrea; Campbell, Peter T.; Carreras-Torres, Robert; Casey, Graham; Chang-Claude, Jenny; Conti, David V.; Devall, Matthew A. M.; Figueiredo, Jane C.; Gruber, Stephen B.; Gsur, Andrea; Gunter, Marc J.; Harrison, Tabitha A.; Hidaka, Akihisa; Hoffmeister, Michael; Huyghe, Jeroen R.; Jenkins, Mark A.; Jordahl, Kristina M.; Kundaje, Anshul; Le Marchand, Loic; Li, Li; Lynch, Brigid M.; Murphy, Neil; Nassir, Rami; Newcomb, Polly A.; Newton, Christina C.; Obon-Santacana, Mireia; Ogino, Shuji; Ose, Jennifer; Pai, Rish K.; Palmer, Julie R.; Papadimitriou, Nikos; Pardamean, Bens; Pellatt, Andrew J.; Peoples, Anita R.; Platz, Elizabeth A.; Rennert, Gad; Ruiz-Narvaez, Edward; Sakoda, Lori C.; Scacheri, Peter C.; Schmit, Stephanie L.; Schoen, Robert E.; Stern, Mariana C.; Su, Yu-Ru; Thomas, Duncan C.; Tian, Yu; Tsilidis, Konstantinos K.; Ulrich, Cornelia M.; Um, Caroline Y.; van Duijnhoven, Fraenzel J. B.; Van Guelpen, Bethany; White, Emily; Hsu, Li; Moreno, Victor; Peters, Ulrike; Chan, Andrew T.; Gauderman, W. James Share Save
Longitudinal associations of plasma kynurenines and ratios with anxiety and depression scores in colorectal cancer survivors up to 12 months post-treatment Holthuijsen, Danielle D. B.; van Roekel, Eline H.; Bours, Martijn J. L.; Ueland, Per M.; Breukink, Stephanie O.; Janssen-Heijnen, Maryska L. G.; Keulen, Eric T. P.; Gigic, Biljana; Gsur, Andrea; Meyer, Klaus; Ose, Jennifer; Ulvik, Arve; Weijenberg, Matty P.; Eussen, Simone J. P. M. Share Save
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes Chen, Zhishan; Guo, Xingyi; Tao, Ran; Huyghe, Jeroen R.; Law, Philip J.; Fernandez-Rozadilla, Ceres; Ping, Jie; Jia, Guochong; Long, Jirong; Li, Chao; Shen, Quanhu; Xie, Yuhan; Timofeeva, Maria N.; Thomas, Minta; Schmit, Stephanie L.; Diez-Obrero, Virginia; Devall, Matthew; Moratalla-Navarro, Ferran; Fernandez-Tajes, Juan; Palles, Claire; Sherwood, Kitty; Briggs, Sarah E. W.; Svinti, Victoria; Donnelly, Kevin; Farrington, Susan M.; Blackmur, James; Vaughan-Shaw, Peter G.; Shu, Xiao-Ou; Lu, Yingchang; Broderick, Peter; Studd, James; Harrison, Tabitha A.; Conti, David V.; Schumacher, Fredrick R.; Melas, Marilena; Rennert, Gad; Obon-Santacana, Mireia; Martin-Sanchez, Vicente; Oh, Jae Hwan; Kim, Jeongseon; Jee, Sun Ha; Jung, Keum Ji; Kweon, Sun-Seog; Shin, Min-Ho; Shin, Aesun; Ahn, Yoon-Ok; Kim, Dong-Hyun; Oze, Isao; Wen, Wanqing; Matsuo, Keitaro; Matsuda, Koichi; Tanikawa, Chizu; Ren, Zefang; Gao, Yu-Tang; Jia, Wei-Hua; Hopper, John L.; Jenkins, Mark A.; Win, Aung Ko; Pai, Rish K.; Figueiredo, Jane C.; Haile, Robert W.; Gallinger, Steven; Woods, Michael O.; Newcomb, Polly A.; Duggan, David; Cheadle, Jeremy P.; Kaplan, Richard; Kerr, Rachel; Kerr, David; Kirac, Iva; Bohm, Jan; Mecklin, Jukka-Pekka; Jousilahti, Pekka; Knekt, Paul; Aaltonen, Lauri A.; Rissanen, Harri; Pukkala, Eero; Eriksson, Johan G.; Cajuso, Tatiana; Hanninen, Ulrika; Kondelin, Johanna; Palin, Kimmo; Tanskanen, Tomas; Renkonen-Sinisalo, Laura; Mannisto, Satu; Albanes, Demetrius; Weinstein, Stephanie J.; Ruiz-Narvaez, Edward; Palmer, Julie R.; Buchanan, Daniel D.; Platz, Elizabeth A.; Visvanathan, Kala; Ulrich, Cornelia M.; Siegel, Erin; Brezina, Stefanie; Gsur, Andrea; Campbell, Peter T.; Chang-Claude, Jenny; Hoffmeister, Michael; Brenner, Hermann; Slattery, Martha L.; Potter, John D.; Tsilidis, Kostas K.; Schulze, Matthias B.; Gunter, Marc J.; Murphy, Neil; Castells, Antoni; Castellvi-Bel, Sergi; Moreira, Leticia; Arndt, Volker; Shcherbina, Anna; Bishop, D. Timothy; Giles, Graham G.; Southey, Melissa C.; Idos, Gregory E.; McDonnell, Kevin J.; Abu-Ful, Zomoroda; Greenson, Joel K.; Shulman, Katerina; Lejbkowicz, Flavio; Offit, Kenneth; Su, Yu-Ru; Steinfelder, Robert; Keku, Temitope O.; van Guelpen, Bethany; Hudson, Thomas J.; Hampel, Heather; Pearlman, Rachel; Berndt, Sonja I.; Hayes, Richard B.; Martinez, Marie Elena; Thomas, Sushma S.; Pharoah, Paul D. P.; Larsson, Susanna C.; Yen, Yun; Lenz, Heinz-Josef; White, Emily; Li, Li; Doheny, Kimberly F.; Pugh, Elizabeth; Shelford, Tameka; Chan, Andrew T.; Cruz-Correa, Marcia; Lindblom, Annika; Hunter, David J.; Joshi, Amit D.; Schafmayer, Clemens; Scacheri, Peter C.; Kundaje, Anshul; Schoen, Robert E.; Hampe, Jochen; Stadler, Zsofia K.; Vodicka, Pavel; Vodickova, Ludmila; Vymetalkova, Veronika; Edlund, Christopher K.; Gauderman, W. James; Shibata, David; Toland, Amanda; Markowitz, Sanford; Kim, Andre; Chanock, Stephen J.; van Duijnhoven, Franzel; Feskens, Edith J. M.; Sakoda, Lori C.; Gago-Dominguez, Manuela; Wolk, Alicja; Pardini, Barbara; FitzGerald, Liesel M.; Lee, Soo Chin; Ogino, Shuji; Bien, Stephanie A.; Kooperberg, Charles; Li, Christopher I.; Lin, Yi; Prentice, Ross; Qu, Conghui; Bezieau, Stephane; Yamaji, Taiki; Sawada, Norie; Iwasaki, Motoki; Le Marchand, Loic; Wu, Anna H.; Qu, Chenxu; McNeil, Caroline E.; Coetzee, Gerhard; Hayward, Caroline; Deary, Ian J.; Harris, Sarah E.; Theodoratou, Evropi; Reid, Stuart; Walker, Marion; Ooi, Li Yin; Lau, Ken S.; Zhao, Hongyu; Hsu, Li; Cai, Qiuyin; Dunlop, Malcolm G.; Gruber, Stephen B.; Houlston, Richard S.; Moreno, Victor; Casey, Graham; Peters, Ulrike; Tomlinson, Ian; Zheng, Wei Share Save
Associations of circulating levels of tryptophan-kynurenine metabolites and inflammation biomarker neopterin with overall survival among patients with stage I-III colorectal cancer Damerell, Victoria; van Roekel, Eline H.; Brezina, Stefanie; Kok, Dieuwertje E.; Lin, Tengda; Holthuijsen, Danielle D.; Ose, Jennifer; Himbert, Caroline; Eussen, Simone J. P.; Ulvik, Arve; van Duijnhoven, Franzel J.; Figueiredo, Jane C.; Li, Christopher I.; Siegel, Erin M.; Schneider, Martin; Shibata, David; Toriola, Adetunji A.; Ulrich, Alexis B.; Ueland, Per M.; Weijenberg, Matty P.; Gsur, Andrea; Kampman, Ellen; Ulrich, Cornelia M.; Gigic, Biljana Share Save
Assessing microsatellite instability dominance in colorectal cancer phenotype: A multi-study initiative using multi-target transformers for genomic biomarker prediction Gustav, Marco; van Treeck, Marko; Carrero, Zunamys I.; Loeffler, Chiara M.; Reitsam, Nic G.; Markl, Bruno; Meneghetti, Asier Rabasco; Boardman, Lisa A.; French, Amy J.; Goode, Ellen L.; Gsur, Andrea; Brezina, Stefanie; Gunter, Marc J.; Murphy, Neil; Limburg, Paul; Thibodeau, Stephen; Foersch, Sebastian; Steinfelder, Robert; Harrison, Tabitha; Peters, Ulrike; Phipps, Amanda; Kather, Jakob N. Share Save
Epidemiologic Factors in Relation to Colorectal Cancer Risk and Survival by Genotoxic Colibactin Mutational Signature Thomas, Claire E.; Georgeson, Peter; Qu, Conghui; Steinfelder, Robert S.; Buchanan, Daniel D.; Song, Mingyang; Harrison, Tabitha A.; Um, Caroline Y.; Hullar, Meredith A.; Jenkins, Mark A.; Van Guelpen, Bethany; Lynch, Brigid M.; Melaku, Yohannes Adama; Huyghe, Jeroen R.; Aglago, Elom K.; Berndt, Sonja I.; Boardman, Lisa A.; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Drew, David A.; Figueiredo, Jane C.; French, Amy J.; Giannakis, Marios; Goode, Ellen L.; Gruber, Stephen B.; Gsur, Andrea; Gunter, Marc J.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Moreno, Victor; Murphy, Neil; Newcomb, Polly A.; Newton, Christina C.; Nowak, Jonathan A.; Obon-Santacana, Mireia; Ogino, Shuji; Sun, Wei; Toland, Amanda E.; Trinh, Quang M.; Ugai, Tomotaka; Zaidi, Syed H.; Peters, Ulrike; Phipps, Amanda I. Share Save
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations Thomas, Minta; Su, Yu-Ru; Rosenthal, Elisabeth A.; Sakoda, Lori C.; Schmit, Stephanie L.; Timofeeva, Maria N.; Chen, Zhishan; Fernandez-Rozadilla, Ceres; Law, Philip J.; Murphy, Neil; Carreras-Torres, Robert; Diez-Obrero, Virginia; van Duijnhoven, Franzel J. B.; Jiang, Shangqing; Shin, Aesun; Wolk, Alicja; Phipps, Amanda I.; Burnett-Hartman, Andrea; Gsur, Andrea; Chan, Andrew T.; Zauber, Ann G.; Wu, Anna H.; Lindblom, Annika; Um, Caroline Y.; Tangen, Catherine M.; Gignoux, Chris; Newton, Christina; Haiman, Christopher A.; Qu, Conghui; Bishop, D. Timothy; Buchanan, Daniel D.; Crosslin, David R.; Conti, David V.; Kim, Dong-Hyun; Hauser, Elizabeth; White, Emily; Siegel, Erin; Schumacher, Fredrick R.; Rennert, Gad; Giles, Graham G.; Hampel, Heather; Brenner, Hermann; Oze, Isao; Oh, Jae Hwan; Lee, Jeffrey K.; Schneider, Jennifer L.; Chang-Claude, Jenny; Kim, Jeongseon; Huyghe, Jeroen R.; Zheng, Jiayin; Hampe, Jochen; Greenson, Joel; Hopper, John L.; Palmer, Julie R.; Visvanathan, Kala; Matsuo, Keitaro; Matsuda, Koichi; Jung, Keum Ji; Li, Li; Le Marchand, Loic; Vodickova, Ludmila; Bujanda, Luis; Gunter, Marc J.; Matejcic, Marco; Jenkins, Mark A.; Slattery, Martha L.; D'Amato, Mauro; Wang, Meilin; Hoffmeister, Michael; Woods, Michael O.; Kim, Michelle; Song, Mingyang; Iwasaki, Motoki; Du, Mulong; Udaltsova, Natalia; Sawada, Norie; Vodicka, Pavel; Campbell, Peter T.; Newcomb, Polly A.; Cai, Qiuyin; Pearlman, Rachel; Pai, Rish K.; Schoen, Robert E.; Steinfelder, Robert S.; Haile, Robert W.; Vandenputtelaar, Rosita; Prentice, Ross L.; Kuery, Sebastien; Castellvi-Bel, Sergi; Tsugane, Shoichiro; Berndt, Sonja I.; Lee, Soo Chin; Brezina, Stefanie; Weinstein, Stephanie J.; Chanock, Stephen J.; Jee, Sun Ha; Kweon, Sun-Seog; Vadaparampil, Susan; Harrison, Tabitha A.; Yamaji, Taiki; Keku, Temitope O.; Vymetalkova, Veronika; Arndt, Volker; Jia, Wei-Hua; Shu, Xiao-Ou; Lin, Yi; Ahn, Yoon-Ok; Stadler, Zsofia K.; Van Guelpen, Bethany; Ulrich, Cornelia M.; Platz, Elizabeth A.; Potter, John D.; Li, Christopher I.; Meester, Reinier; Moreno, Victor; Figueiredo, Jane C.; Casey, Graham; Lansdorp Vogelaar, Iris; Dunlop, Malcolm G.; Gruber, Stephen B.; Hayes, Richard B.; Pharoah, Paul D. P.; Houlston, Richard S.; Jarvik, Gail P.; Tomlinson, Ian P.; Zheng, Wei; Corley, Douglas A.; Peters, Ulrike; Hsu, Li Share Save
Novel insights into genetic susceptibility for colorectal cancer from transcriptome-wide association and functional investigation Chen, Zhishan; Song, Wenqiang; Shu, Xiao-Ou; Wen, Wanqing; Devall, Matthew; Dampier, Christopher; Moratalla-Navarro, Ferran; Cai, Qiuyin; Long, Jirong; Van Kaer, Luc; Wu, Lan; Huyghe, Jeroen R.; Thomas, Minta; Hsu, Li; Woods, Michael O.; Albanes, Demetrius; Buchanan, Daniel D.; Gsur, Andrea; Hoffmeister, Michael; Vodicka, Pavel; Wolk, Alicja; Le Marchand, Loic; Wu, Anna H.; Phipps, Amanda I.; Moreno, Victor; Ulrike, Peters; Zheng, Wei; Casey, Graham; Guo, Xingyi Share Save
Probing the diabetes and colorectal cancer relationship using gene - environment interaction analyses Dimou, Niki; Kim, Andre E.; Flanagan, Orlagh; Murphy, Neil; Diez-Obrero, Virginia; Shcherbina, Anna; Aglago, Elom K.; Bouras, Emmanouil; Campbell, Peter T.; Casey, Graham; Gallinger, Steven; Gruber, Stephen B.; Jenkins, Mark A.; Lin, Yi; Moreno, Victor; Ruiz-Narvaez, Edward; Stern, Mariana C.; Tian, Yu; Tsilidis, Kostas K.; Arndt, Volker; Barry, Elizabeth L.; Baurley, James W.; Berndt, Sonja I.; Bezieau, Stephane; Bien, Stephanie A.; Bishop, D. Timothy; Brenner, Hermann; Budiarto, Arif; Carreras-Torres, Robert; Cenggoro, Tjeng Wawan; Chan, Andrew T.; Chang-Claude, Jenny; Chanock, Stephen J.; Chen, Xuechen; Conti, David V.; Dampier, Christopher H.; Devall, Matthew; Drew, David A.; Figueiredo, Jane C.; Giles, Graham G.; Gsur, Andrea; Harrison, Tabitha A.; Hidaka, Akihisa; Hoffmeister, Michael; Huyghe, Jeroen R.; Jordahl, Kristina; Kawaguchi, Eric; Keku, Temitope O.; Larsson, Susanna C.; Le Marchand, Loic; Lewinger, Juan Pablo; Li, Li; Mahesworo, Bharuno; Morrison, John; Newcomb, Polly A.; Newton, Christina C.; Obon-Santacana, Mireia; Ose, Jennifer; Pai, Rish K.; Palmer, Julie R.; Papadimitriou, Nikos; Pardamean, Bens; Peoples, Anita R.; Pharoah, Paul D. P.; Platz, Elizabeth A.; Potter, John D.; Rennert, Gad; Scacheri, Peter C.; Schoen, Robert E.; Su, Yu-Ru; Tangen, Catherine M.; Thibodeau, Stephen N.; Thomas, Duncan C.; Ulrich, Cornelia M.; Um, Caroline Y.; van Duijnhoven, Franzel J. B.; Visvanathan, Kala; Vodicka, Pavel; Vodickova, Ludmila; White, Emily; Wolk, Alicja; Woods, Michael O.; Qu, Conghui; Kundaje, Anshul; Hsu, Li; Gauderman, W. James; Gunter, Marc J.; Peters, Ulrike Share Save
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