John O’Leary - Publications, H-index & Citations

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John O’Leary

Trinity College Dublin

59H-index

515Paper Count

1.4WCitation Count

Published Papers 132

Publication Date

Lipid metabolism in γδ T-cell activation: Implications for immunotherapy in ovarian cancer

Translational Oncology

IF4.1

2026-07-27

OAAI

Karolina Stirblyte; Yazid Ghanem; Mark Bates; Steven G. Gray; Feras Abu Saadeh; Cara Martin; Sharon O'Toole; John J. O'Leary; Derek G. Doherty; Bashir M. Mohamed

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Crosstalk Between Inflammasome Signalling and Epithelial-Mesenchymal Transition in Cancer and Benign Disease: Mechanistic Insights, Context-Dependence, and Therapeutic Opportunities

Cells

IF5.2

2026-03-03

OAAI

Abdul L. Shakerdi; Emma Finnegan; Yin-Yin Sheng; Karlo Vidovic; Jessica M. Logan; Mark P. Ward; Sharon A. O’Toole; Cara Martin; Stavros Selemidis; Doug Brooks; John J. O’Leary; Prerna Tewari

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TLR7-mediated inflammation drives PD-L1 upregulation and T cell exhaustion during influenza A virus infection

iScience

IF4.1

2026-01-22

OAAI

Mark A. Miles; Stella Liong; Felicia Liong; John J. O’Leary; Doug A. Brooks; Stavros Selemidis

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Pathogenesis-Guided Biomarker Assessment: A Shift in Prostate Cancer Diagnostics

International Journal of Molecular Sciences

IF4.9

2025-12-05

OAAI

Jessica M. Logan; Victoria Malone; John J. O’Leary; Doug A. Brooks

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Implications of Altered Endosomal–Lysosomal Biogenesis in Melanoma Pathogenesis

International Journal of Molecular Sciences 2025, Vol. 26, Page 10113

IF0

2025-10-17

OAAI

Giang T. Lam; Carmela Martini; Alexandra Sorvina; Shane M. Hickey; Madison T. Hindes; David Waugh; John J. O’Leary; Douglas A. Brooks; Jessica M. Logan

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Circulating tumour cells are a prognostic indicator in advanced high-grade serous ovarian cancer and are associated with platelets and immune cells following dissemination

British Journal of Cancer

IF6.8

2025-10-10

OAAI

Mark P. Ward; Faye Lewis; Catherine O’Gorman; Lucy A. Norris; Sarah E. Lochrin; Laura E. Kane; Tanya E. Kelly; Bashir M. Mohamed; Ashitha Ramesh; Roisin O’Connor; Elaine Kilgour; Brian Henderson; Marika Kanjuga; Sinead Hurley; Laura Edgerton; Prerna Tewari; Kathy Gately; Lorraine O’Driscoll; Karsten Hokamp; Siobhan Cashman; Gavin McManus; Doug A. Brooks; Stavros Selemidis; Niamh Coleman; John Kennedy; Waseem Kamran; James P. Beirne; Patrick Maguire; Feras Abu Saadeh; Karen Cadoo; Cara M. Martin; John J. O’Leary; Sharon A. O’Toole

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Reply to: In reference to “A pilot study evaluating the feasibility of enriching and detecting circulating tumour cells from peripheral and ovarian veins in rare epithelial ovarian carcinomas”

european journal of oncology

IF0

2025-06-02

PREAI

Faye Lewis; Mark P. Ward; Feras Abu Saadeh; John J. O'Leary; Sharon A. O'Toole

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Exploring the Contribution of TLR7 to Sex-Based Disparities in Respiratory Syncytial Virus (RSV)-Induced Inflammation and Immunity

VIRUSES-BASEL

IF3.5

2025-03-16

OAAI

Miles, Mark A.; Huttmann, Thomas D.; Liong, Stella; Liong, Felicia; O'Leary, John J.; Brooks, Doug A.; Selemidis, Stavros

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Genetics And Survival Outcomes In Young-Onset Ovarian Cancer: Insights From An 18-Year Tertiary Referral Center Study

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

IF4.7

2025-02-01

PREAI

Mcnevin, Ciara; Dillion, Rachel; Hollingsworth, Simon; Lewis, Faye; Hurley, Sinead; Norris, Lucy A.; Ward, Mark; Donachie, Vicky; Maguire, Patrick J.; Alken, Scheryll; Coleman, Niamh; Kamran, Waseem; Abu Saadeh, Feras; O'Gorman, Catherine; Donnell, Dearbhaile O.; D'Arcy, Tom; O'Leary, John; Finn, Stephen; O'Toole, Sharon A.; Cadoo, Karen

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Metabolic reprogramming, malignant transformation and metastasis: Lessons from chronic lymphocytic leukaemia and prostate cancer

CANCER LETTERS

IF10.1

2025-02-01

PREAI

Hindes, Madison T.; Mcelligott, Anthony M.; Best, Oliver G.; Ward, Mark P.; Selemidis, Stavros; Miles, Mark A.; Nturubika, Bukuru D.; Gregory, Philip A.; Anderson, Paul H.; Logan, Jessica M.; Butler, Lisa M.; Waugh, David J.; O'Leary, John J.; Hickey, Shane M.; Thurgood, Lauren A.; Brooks, Douglas A.

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Chemotherapy alters thrombomodulin and factor VIIIc expression resulting in acquired activated protein C resistance and enhanced thrombin generation in cancer associated thrombosis

THROMBOSIS RESEARCH

IF3.4

2025-02-01

OAAI

Ward, M. P.; Ibrahim, E. M.; O'Toole, S. A.; Marchocki, Z.; O'Leary, J. J.; Abu Saadeh, F.; Norris, L. A.

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Unravelling the biological and clinical challenges of circulating tumour cells in epithelial ovarian carcinoma

CANCER LETTERS

IF10.1

2024-11-01

OAAI

Lewis, Faye; Beirne, James; Henderson, Brian; Norris, Lucy; Cadoo, Karen; Kelly, Tanya; Martin, Cara; Hurley, Sinead; Kanjuga, Marika; O'Driscoll, Lorraine; Gately, Kathy; Oner, Ezgi; Saini, Volga M.; Brooks, Doug; Selemidis, Stavros; Kamran, Waseem; Haughey, Niamh; Maguire, Patrick; O'Gorman, Catherine; Abu Saadeh, Feras; Ward, Mark P.; O'Leary, John J.; O'Toole, Sharon A.

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Biomarkers in high grade serous ovarian cancer

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

IF8.3

2024-11-01

PREAI

Bates, Mark; Mohamed, Bashir M.; Lewis, Faye; O'Toole, Sharon; O'Leary, John J.

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Altered expression of vesicular trafficking machinery in prostate cancer affects lysosomal dynamics and provides insight into the underlying biology and disease progression

BRITISH JOURNAL OF CANCER

IF6.8

2024-08-31

OAAI

Nturubika, Bukuru D.; Guardia, Carlos M.; Gershlick, David C.; Logan, Jessica M.; Martini, Carmela; Heatlie, Jessica K.; Lazniewska, Joanna; Moore, Courtney; Lam, Giang T.; Li, Ka L.; Ung, Ben S-Y; Brooks, Robert D.; Hickey, Shane M.; Bert, Andrew G.; Gregory, Philip A.; Butler, Lisa M.; O'Leary, John J.; Brooks, Douglas A.; Johnson, Ian R. D.

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Potential role of the CD39-CD73 ATP-adenosine pathway in platelet mediated dissemination of circulating tumour cells

BRITISH JOURNAL OF CANCER

IF6.8

2024-08-11

PREAI

Ward, Mark P.; O'Toole, Sharon A.; O'Leary, John J.

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A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

MOLECULAR ONCOLOGY

IF4.5

2024-08-06

OAAI

Saini, Volga; Oner, Ezgi; Ward, Mark P.; Hurley, Sinead; Henderson, Brian David; Lewis, Faye; Finn, Stephen P.; Fitzmaurice, Gerard J.; O'Leary, John J.; O'Toole, Sharon; O'Driscoll, Lorraine; Gately, Kathy

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Low dose aspirin prevents endothelial dysfunction in the aorta and foetal loss in pregnant mice infected with influenza A virus

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-04-04

OAAI

Coward-Smith, Madison; Liong, Stella; Oseghale, Osezua; Erlich, Jonathan R.; Miles, Mark A.; Liong, Felicia; Brassington, Kurt; Bozinovski, Steven; Vlahos, Ross; Brooks, Robert D.; Brooks, Doug A.; O'Leary, John J.; Selemidis, Stavros

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Exploring the role of sporadic BRAF and KRAS mutations during colorectal cancer pathogenesis: A spotlight on the contribution of the endosome-lysosome system

CANCER LETTERS

IF10.1

2024-03-01

OAAI

Tang, Jingying; Lam, Giang T.; Brooks, Robert D.; Miles, Mark; Useckaite, Zivile; Johnson, Ian R. D.; Ung, Ben S. -Y.; Martini, Carmela; Karageorgos, Litsa; Hickey, Shane M.; Selemidis, Stavros; Hopkins, Ashley M.; Rowland, Andrew; Vather, Ryash; O'Leary, John J.; Brooks, Douglas A.; Caruso, Maria C.; Logan, Jessica M.

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TLR9 Monotherapy in Immune-Competent Mice Suppresses Orthotopic Prostate Tumor Development

CELLS

IF5.2

2024-01-02

OAAI

Miles, Mark A.; Luong, Raymond; To, Eunice E.; Erlich, Jonathan R.; Liong, Stella; Liong, Felicia; Logan, Jessica M.; O'Leary, John; Brooks, Doug A.; Selemidis, Stavros

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Appl1, Sortilin and Syndecan-1 immunohistochemistry on intraductal carcinoma of the prostate provides evidence of retrograde spread

PATHOLOGY

IF3

2023-10-01

OAAI

Sorvina, Alexandra; Martini, Carmela; Prabhakaran, Sarita; Logan, Jessica M.; Ung, Benjamin S-Y.; Moore, Courtney; Johnson, Ian R. D.; Lazniewska, Joanna; Tewari, Prerna; Malone, Victoria; Brooks, Robert D.; Hickey, Shane M.; Caruso, Maria C.; Klebe, Sonja; Karageorgos, Litsa; O'leary, John J.; Delahunt, Brett; Samaratunga, Hemamali; Brooks, Doug A.

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Research Directions