Not logged in Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target Ahmad, Shiekh Tanveer; Li, Yiran; Garcia-Lopez, Jesus; Gudenas, Brian; Hadley, Jennifer; Paul, Leena; Wu, Stephanie; Refaat, Alaa; Kojic, Marija; Batts, Melissa; Soliman, Taha; Pitre, Aaron; Arnskotter, Frederik; Zindy, Frederique; Jones, Alun; Twarog, Nathaniel; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura; Lu, Meifen; Lewis, Sara; Onar-Thomas, Arzu; Pfister, Stefan; Gajjar, Amar; Baker, Suzanne; Roussel, Martine; Rankovic, Zoran; Robinson, Giles; Orr, Brent; Wainwright, Brandon; Shelat, Anang; Waszak, Sebastian; Kutscher, Lena; Lin, Hong; Northcott, Paul Share Save
GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA Tanveer Ahmad, Shiekh; Garcia-Lopez, Jesus; Li, Yiran; Hadley, Jennifer; Paul, Leena; Gudenas, Brian; Batts, Melissa; Soliman, Taha; Pitre, Aaron; Kojic, Marija; Manz, Frederik; Zindy, Frederique; Jones, Alun; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura Janke; Lu, Meifen; Onar-Thomas, Arzu; Pfister, Stefan; Gajjar, Amar; Baker, Suzanne; Roussel, Martine; Rankovic, Zoran; Robinson, Giles; Orr, Brent; Wainwright, Brandon; Kutscher, Lena; Waszak, Sebastian; Lin, Hong; Northcott, Paul Share Save
If you build it, they will come: the convergence of funding, research and collaboration in paediatric brain cancer clinical trials Hansford, Jordan; Valvi, Santosh; de Boer, Jasper; McCowage, Geoff; Govender, Dinisha; Kirby, Maria; Ziegler, David; Manoharan, Neevika; Hassall, Timothy; Wainwright, Brandon; Alvaro, Frank; Wood, Paul J.; Eisenstat, David; Quang, Dong Anh Khuong; Jenkins, Misty; Dun, Matthew; Laughton, Stephen J.; Endersby, Raelene; Dodgshun, Andrew; Gottardo, Nicholas Share Save
GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA Ahmad, Shiekh Tanveer; Garcia-Lopez, Jesus; Li, Yiran; Gudenas, Brian; Hadley, Jennifer; Paul, Leena; Batts, Melissa; Soliman, Taha; Kojic, Marija; Pitre, Aaron; Manz, Frederik; Zindy, Frederique; Jones, Alun; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura; Lu, Meifen; Pfister, Stefan M.; Gajjar, Amar; Baker, Suzanne J.; Roussel, Martine F.; Rankovic, Zoran; Waszak, Sebastian M.; Robinson, Giles W.; Orr, Brent A.; Wainwright, Brandon; Kutscher, Lena M.; Lin, Hong; Northcott, Paul A. Share Save
The Virtual Child Gilbertson, Richard J.; Behjati, Sam; Boettcher, Anna-Lisa; Bronner, Marianne E.; Burridge, Matthew; Clausing, Henrick; Clifford, Harry; Danaher, Tracey; Donovan, Laura K.; Drost, Jarno; Eggermont, Alexander M. M.; Emerson, Chris; Flores, Mona G.; Hamerlik, Petra; Jabado, Nada; Jones, Andrew; Kaessmann, Henrick; Kleinman, Claudia L.; Kool, Marcel; Kutscher, Lena M.; Lindberg, Gavin; Linnane, Emily; Marioni, John C.; Maris, John M.; Monje, Michelle; Macaskill, Alexandra; Niederer, Steven; Northcott, Paul A.; Peeters, Elizabeth; Plieger-van Solkema, Willemijn; Preussner, Liane; Rios, Anne C.; Rippe, Karsten; Sandford, Peter; Sgourakis, Nikolaos G.; Shlien, Adam; Smith, Pete; Straathof, Karin; Sullivan, Patrick J.; Suva, Mario L.; Taylor, Michael D.; Thompson, Emma; Vento-Tormo, Roser; Wainwright, Brandon J.; Wechsler-Reya, Robert J.; Westermann, Frank; Winslade, Shannon; Al-Lazikani, Bissan; Pfister, Stefan M. Share Save
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Efficient detection and monitoring of pediatric brain malignancies with liquid biopsy based on patient-specific somatic mutation screening Kojic, Marija; Maybury, Mellissa K.; Waddell, Nicola; Koufariotis, Lambros T.; Addala, Venkateswar; Millar, Amanda; Wood, Scott; Pearson, John, V; Hansford, Jordan R.; Hassall, Tim; Wainwright, Brandon J. Share Save
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SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation Adolphe, Christelle; Millar, Amanda; Kojic, Marija; Barkauskas, Deborah S.; Sundstrom, Anders; Swartling, Fredrik J.; Hediyeh-Zadeh, Soroor; Tan, Chin Wee; Davis, Melissa J.; Genovesi, Laura A.; Wainwright, Brandon J. Share Save
Tumor cells generate astrocyte-like cells that contribute to SHH-driven medulloblastoma relapse Guo, Duancheng; Wang, Yuan; Cheng, Yan; Liao, Shengyou; Hu, Jian; Du, Fang; Xu, Gang; Liu, Yongqiang; Cai, Kathy Q.; Cheung, Martin; Wainwright, Brandon J.; Lu, Q. Richard; Zhao, Yi; Yang, Zeng-jie Share Save
Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype Kojic, Marija; Gawda, Tomasz; Gaik, Monika; Begg, Alexander; Salerno-Kochan, Anna; Kurniawan, Nyoman D.; Jones, Alun; Drozdzyk, Katarzyna; Koscielniak, Anna; Chramiec-Glabik, Andrzej; Hediyeh-Zadeh, Soroor; Kasherman, Maria; Shim, Woo Jun; Sinniah, Enakshi; Genovesi, Laura A.; Abrahamsen, Rannva K.; Fenger, Christina D.; Madsen, Camilla G.; Cohen, Julie S.; Fatemi, Ali; Stark, Zornitza; Lunke, Sebastian; Lee, Joy; Hansen, Jonas K.; Boxill, Martin F.; Keren, Boris; Marey, Isabelle; Saenz, Margarita S.; Brown, Kathleen; Alexander, Suzanne A.; Mureev, Sergey; Batzilla, Alina; Davis, Melissa J.; Piper, Michael; Boden, Mikael; Burne, Thomas H. J.; Palpant, Nathan J.; Moller, Rikke S.; Glatt, Sebastian; Wainwright, Brandon J. Share Save
Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release Starobova, Hana; Monteleone, Mercedes; Adolphe, Christelle; Batoon, Lena; Sandrock, Cheyenne J.; Tay, Bryan; Deuis, Jennifer R.; Smith, Alexandra V.; Mueller, Alexander; Nadar, Evelyn Israel; Lawrence, Grace Pamo; Mayor, Amanda; Tolson, Elissa; Levesque, Jean-Pierre; Pettit, Allison R.; Wainwright, Brandon J.; Schroder, Kate; Vetter, Irina Share Save
Patient-derived orthotopic xenograft models of medulloblastoma lack a functional blood-brain barrier Genovesi, Laura A.; Puttick, Simon; Millar, Amanda; Kojic, Marija; Ji, Pengxiang; Lagendijk, Anne K.; Brighi, Caterina; Bonder, Claudine S.; Adolphe, Christelle; Wainwright, Brandon J. Share Save
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Elongator mutation in mice induces neurodegeneration and ataxia-like behavior Kojic, Marija; Gaik, Monika; Kiska, Bence; Salerno-Kochan, Anna; Hunt, Sarah; Tedoldi, Angelo; Mureev, Sergey; Jones, Alun; Whittle, Belinda; Genovesi, Laura A.; Adolphe, Christelle; Brown, Darren L.; Stow, Jennifer L.; Alexandrov, Kirill; Sah, Pankaj; Glatt, Sebastian; Wainwright, Brandon J. Share Save
Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction Sheybani-Deloui, Sepideh; Chi, Lijun; Staite, Marian V.; Cain, Jason E.; Nieman, Brian J.; Henkelman, R. Mark; Wainwright, Brandon J.; Potter, S. Steven; Bagli, Darius J.; Lorenzo, Armando J.; Rosenblum, Norman D. Share Save
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