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SaveShare Save Share Save LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells
Kumar, Dhiraj; Gurrapu, Sreeharsha; Wang, Yan; Bae, Seong-Yeon; Pandey, Poonam R.; Chen, Hong; Mondal, Jayanta; Han, Hyunho; Wu, Chang-Jiun; Karaiskos, Spyros; Yang, Fei; Sahin, Aysegul; Wistuba, Ignacio I.; Gao, Jianjun; Tripathy, Debasish; Gao, Hua; Izar, Benjamin; Giancotti, Filippo G. Share Save Share Save Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer ProgressionHsu, Wen-Hao; LaBella, Kyle A.; Lin, Yiyun; Xu, Ping; Lee, Rumi; Hsieh, Cheng-En; Yang, Lei; Zhou, Ashley; Blecher, Jonathan M.; Wu, Chang-Jiun; Lin, Kangyu; Shang, Xiaoying; Jiang, Shan; Spring, Denise J.; Xia, Yan; Chen, Peiwen; Shen, John Paul; Kopetz, Scott; DePinho, Ronald A. Share Save Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancerGulhati, Pat; Schalck, Aislyn; Jiang, Shan; Shang, Xiaoying; Wu, Chang-Jiun; Hou, Pingping; Ruiz, Sharia Hernandez; Soto, Luisa Solis; Parra, Edwin; Ying, Haoqiang; Han, Jincheng; Dey, Prasenjit; Li, Jun; Deng, Pingna; Sei, Emi; Maeda, Dean Y.; Zebala, John A.; Spring, Denise J.; Kim, Michael; Wang, Huamin; Maitra, Anirban; Moore, Dirk; Clise-Dwyer, Karen; Wang, Y. Alan; Navin, Nicholas E.; DePinho, Ronald A. Share Save Share Save Multi-modal molecular programs regulate melanoma cell stateAndrews, Miles C.; Oba, Junna; Wu, Chang-Jiun; Zhu, Haifeng; Karpinets, Tatiana; Creasy, Caitlin A.; Forget, Marie-Andree; Yu, Xiaoxing; Song, Xingzhi; Mao, Xizeng; Robertson, A. Gordon; Romano, Gabriele; Li, Peng; Burton, Elizabeth M.; Lu, Yiling; Sloane, Robert Szczepaniak; Wani, Khalida M.; Rai, Kunal; Lazar, Alexander J.; Haydu, Lauren E.; Bustos, Matias A.; Shen, Jianjun; Chen, Yueping; Morgan, Margaret B.; Wargo, Jennifer A.; Kwong, Lawrence N.; Haymaker, Cara L.; Grimm, Elizabeth A.; Hwu, Patrick; Hoon, Dave S. B.; Zhang, Jianhua; Gershenwald, Jeffrey E.; Davies, Michael A.; Futreal, P. Andrew; Bernatchez, Chantale; Woodman, Scott E. Share Save Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal CancerLee, Rumi; Li, Jiexi; Li, Jun; Wu, Chang-Jiun; Jiang, Shan; Hsu, Wen-Hao; Chakravarti, Deepavali; Chen, Peiwen; LaBella, Kyle A.; Li, Jing; Spring, Denise J.; Zhao, Di; Wang, Y. Alan; DePinho, Ronald A. Share Save Telomerase reverse transcriptase preserves neuron survival and cognition in Alzheimer's disease modelsShim, Hong Seok; Horner, James W.; Wu, Chang-Jiun; Li, Jiexi; Lan, Zheng D.; Jiang, Shan; Xu, Xueping; Hsu, Wen-Hao; Zal, Tomasz; Flores, Ivonne I.; Deng, Pingna; Lin, Yuan-Ta; Tsai, Li-Huei; Wang, Y. Alan; DePinho, Ronald A. Share Save Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancerChen, Ming; Chen, Runzhe; Jin, Ying; Li, Jun; Hu, Xin; Zhang, Jiexin; Fujimoto, Junya; Hubert, Shawna M.; Gay, Carl M.; Zhu, Bo; Tian, Yanhua; McGranahan, Nicholas; Lee, Won-Chul; George, Julie; Hu, Xiao; Chen, Yamei; Wu, Meijuan; Behrens, Carmen; Chow, Chi-Wan; Pham, Hoa H. N.; Fukuoka, Junya; Wu, Jia; Parra, Edwin Roger; Little, Latasha D.; Gumbs, Curtis; Song, Xingzhi; Wu, Chang-Jiun; Diao, Lixia; Wang, Qi; Cardnell, Robert; Zhang, Jianhua; Wang, Jing; Le, Xiuning; Gibbons, Don L.; Heymach, John, V; Lee, J. Jack; William, William N., Jr.; Cheng, Chao; Glisson, Bonnie; Wistuba, Ignacio; Futreal, P. Andrew; Thomas, Roman K.; Reuben, Alexandre; Byers, Lauren A.; Zhang, Jianjun Share Save AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylaseYoshihama, Yohei; LaBella, Kyle A.; Kim, Eiru; Bertolet, Lori; Colic, Medina; Li, Jiexi; Shang, Xiaoying; Wu, Chang-Jiun; Spring, Denise J.; Wang, Y. Alan; Hart, Traver; DePinho, Ronald A. Share Save Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancerNegrao, Marcelo, V; Skoulidis, Ferdinandos; Montesion, Meagan; Schulze, Katja; Bara, Ilze; Shen, Vincent; Xu, Hao; Hu, Sylvia; Sui, Dawen; Elamin, Yasir Y.; Le, Xiuning; Goldberg, Michael E.; Murugesan, Karthikeyan; Wu, Chang-Jiun; Zhang, Jianhua; Barreto, David S.; Robichaux, Jacqulyne P.; Reuben, Alexandre; Cascone, Tina; Gay, Carl M.; Mitchell, Kyle G.; Hong, Lingzhi; Rinsurongkawong, Waree; Roth, Jack A.; Swisher, Stephen G.; Lee, Jack; Tsao, Anne; Papadimitrakopoulou, Vassiliki; Gibbons, Don L.; Glisson, Bonnie S.; Singal, Gaurav; Miller, Vincent A.; Alexander, Brian; Frampton, Garrett; Albacker, Lee A.; Shames, David; Zhang, Jianjun; Heymach, John, V Share Save Telomere dysfunction instigates inflammation in inflammatory bowel diseaseChakravarti, Deepavali; Lee, Rumi; Multani, Asha S.; Santoni, Andrea; Keith, Zachery; Hsu, Wen-Hao; Chang, Kyle; Reyes, Laura; Rashid, Asif; Wu, Chang-Jiun; Li, Jun; Zhang, Jiexin; Shim, Hong Seok; Chandra, Krishna; Deng, Pingna; Spring, Denise J.; Nielsen, Ole Haagen; Riis, Lene Buhl; Mayigegowda, Kavya Kelagere; Blutt, Sarah E.; Zhang, Jianhua; Younes, Mamoun; DuPont, Andrew; Thirumurthi, Selvi; Vilar, Eduardo; Estes, Mary K.; Colla, Simona; Shroyer, Noah F.; DePinho, Ronald A. Share Save Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategyTerranova, Christopher J.; Tang, Ming; Maitituoheti, Mayinuer; Raman, Ayush T.; Ghosh, Archit K.; Schulz, Jonathan; Amin, Samir B.; Orouji, Elias; Tomczak, Katarzyna; Sarkar, Sharmistha; Oba, Junna; Creasy, Caitlin; Wu, Chang-Jiun; Khan, Samia; Lazcano, Rossana; Wani, Khalida; Singh, Anand; Barrodia, Praveen; Zhao, Dongyu; Chen, Kaifu; Haydu, Lauren E.; Wang, Wei-Lien; Lazar, Alexander J.; Woodman, Scott E.; Bernatchez, Chantale; Rai, Kunal Share Save Share Save Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticityLee, Won-Chul; Reuben, Alexandre; Hu, Xin; McGranahan, Nicholas; Chen, Runzhe; Jalali, Ali; Negrao, Marcelo, V; Hubert, Shawna M.; Tang, Chad; Wu, Chia-Chin; San Lucas, Anthony; Roh, Whijae; Suda, Kenichi; Kim, Jihye; Tan, Aik-Choon; Peng, David H.; Lu, Wei; Tang, Ximing; Chow, Chi-Wan; Fujimoto, Junya; Behrens, Carmen; Kalhor, Neda; Fukumura, Kazutaka; Coyle, Marcus; Thornton, Rebecca; Gumbs, Curtis; Li, Jun; Wu, Chang-Jiun; Little, Latasha; Roarty, Emily; Song, Xingzhi; Lee, J. Jack; Sulman, Erik P.; Rao, Ganesh; Swisher, Stephen; Diao, Lixia; Wang, Jing; Heymach, John, V; Huse, Jason T.; Scheet, Paul; Wistuba, Ignacio I.; Gibbons, Don L.; Futreal, P. Andrew; Zhang, Jianhua; Gomez, Daniel; Zhang, Jianjun Share Save Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment, in PTEN-Deficient Prostate CancerZhao, Di; Cai, Li; Lu, Xin; Liang, Xin; Li, Jiexi; Chen, Peiwen; Ittmann, Michael; Shang, Xiaoying; Jiang, Shan; Li, Haoyan; Meng, Chenling; Flores, Ivonne; Song, Jian H.; Horner, James W.; Lan, Zhengdao; Wu, Chang-Jiun; Li, Jun; Chang, Qing; Chen, Ko-Chien; Wang, Guocan; Deng, Pingna; Spring, Denise J.; Wang, Y. Alan; DePinho, Ronald A. Share Save Share Save 
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