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Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients as diagnostic and monitoring biomarker: impact of tumor localization and sampling method Madlener, S; Stepien, N; Senfter, D; Mayr, L; Laemmerer, A; Hedrich, C; Baumgartner, A; Lötsch-Gojo, D; Sterba, J; Pokorna, P; Kiesel, B; Widhalm, G; Eckert, F; Preusser, M; Rössler, K; Azizi, A; Peyrl, A; Czech, T; Haberler, C; Slavc, I; Kasprian, G; Dorfer, C; Furtner, J; Gojo, J Share Save
Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits Curylova, Lucie; Zambo, Iva Staniczkova; Neradil, Jakub; Kyr, Michal; Jurackova, Nicola; Pavlova, Sarka; Polaskova, Kristyna; Mudry, Peter; Sterba, Jaroslav; Veselska, Renata; Skoda, Jan Share Save
Real-World Performance of Integrative Clinical Genomics in Pediatric Precision Oncology Pokorna, Petra; Palova, Hana; Adamcova, Sona; Jugas, Robin; Al Tukmachi, Dagmar; Kyr, Michal; Knoflickova, Dana; Kozelkova, Katerina; Bystry, Vojtech; Mejstrikova, Sona; Merta, Tomas; Trachtova, Karolina; Podlipna, Eliska; Mudry, Peter; Pavelka, Zdenek; Bajciova, Viera; Tinka, Pavel; Jarosova, Marie; Ivkovic, Tina Catela; Madlener, Sibylle; Pal, Karol; Stepien, Natalia; Mayr, Lisa; Tichy, Boris; Drabova, Klara; Jezova, Marta; Kozakova, Sarka; Vanackova, Jitka; Radova, Lenka; Steininger, Karin; Haberler, Christine; Gojo, Johannes; Sterba, Jaroslav; Slaby, Ondrej Share Save
Diagnostic efficacy and clinical utility of whole-exome sequencing in Czech pediatric patients with rare and undiagnosed diseases Slaba, Katerina; Pokorna, Petra; Jugas, Robin; Palova, Hana; Prochazkova, Dagmar; Aulicka, Stefania; Spanelova, Klara; Danhofer, Pavlina; Horak, Ondrej; Tuckova, Jana; Kleiblova, Petra; Gaillyova, Renata; Hrunka, Matej; Jouza, Martin; Pinkova, Blanka; Papez, Jan; Konecna, Petra; Zidkova, Jana; Stourac, Petr; Sterba, Jaroslav; Demlova, Regina; Demlova, Eva; Jabandziev, Petr; Slaby, Ondrej Share Save
A computational workflow for analysis of missense mutations in precision oncology Khan, Rayyan Tariq; Pokorna, Petra; Stourac, Jan; Borko, Simeon; Arefiev, Ihor; Planas-Iglesias, Joan; Dobias, Adam; Pinto, Gaspar; Szotkowska, Veronika; Sterba, Jaroslav; Slaby, Ondrej; Damborsky, Jiri; Mazurenko, Stanislav; Bednar, David Share Save
Personalized dendritic cell vaccine in multimodal individualized combination therapy improves survival in high-risk pediatric cancer patients Kyr, Michal; Mudry, Peter; Polaskova, Kristyna; Dubska, Lenka Zdrazilova; Demlova, Regina; Kubatova, Jana; Hlavackova, Eva; Pilatova, Katerina Cerna; Mazanek, Pavel; Vejmelkova, Klara; Dusek, Vitezslav; Tinka, Pavel; Balaz, Martin; Merta, Tomas; Kuttnerova, Zuzana; Turekova, Terezia; Pavelka, Zdenek; Pokorna, Petra; Palova, Hana; Mlnarikova, Marie; Jezova, Marta; Kellnerova, Renata; Kozakova, Sarka; Slaby, Ondrej; Valik, Dalibor; Sterba, Jaroslav Share Save
22-HDOHE, A PREDICTIVE MARKER IN CSF OF PATIENTS WITH RECURRENT MEDULLOBLASTOMA TREATED WITH MEMMAT Peyrl, Andreas; Hagn, Gerhard; Stepien, Natalia; Senfter, Daniel; Madlener, Sibylle; Sterba, Jaroslav; Lassaletta, Alvaro; Leblond, Pierre; Nysom, Karsten; Haberler, Christine; Bileck, Andrea; Azizi, Amedeo A.; Mayr, Lisa; Gojo, Johannes; Slavc, Irene; Gerner, Christopher Share Save
SUBGROUP AND SUBTYPE-SPECIFIC OUTCOMES IN METASTATIC INFANT MEDULLOBLASTOMA Senapati, Akanksha; Lindsay, Holly; Gilheeney, Stephen; Bale, Tejus; Taylor, Michael; Khuong-Quang, Dong-Anh; Bouffet, Eric; Khan, Sara; van Veelan, Marie-Lise; Kros, Johan M.; Vasiljevic, Alexandre; Pollack, Ian; Chambless, Lola; Gupta, Nalin; Weiss, William A.; Jabado, Nada; Sterba, Jaroslav; Zapotocky, Michal; Hansford, Jordan R.; Ramaswamy, Vijay Share Save
Precision immuno-oncology approach for four malignant tumors in siblings with constitutional mismatch repair deficiency syndrome Palova, Hana; Das, Anirban; Pokorna, Petra; Bajciova, Viera; Pavelka, Zdenek; Jezova, Marta; Pal, Karol; Dimayacyac, Jose R.; Negm, Logine; Stengs, Lucie; Bianchi, Vanessa; Vejmelkova, Klara; Noskova, Kristyna; Jarosova, Marie; Mejstrikova, Sona; Mudry, Peter; Kyr, Michal; Merta, Tomas; Tinka, Pavel; Drabova, Klara; Aulicka, Stefania; Jugas, Robin; Tabori, Uri; Slaby, Ondrej; Sterba, Jaroslav Share Save
Tazemetostat in the therapy of pediatric INI1-negative malignant rhabdoid tumors Vejmelkova, Klara; Pokorna, Petra; Noskova, Kristyna; Faustmannova, Anna; Drabova, Klara; Pavelka, Zdenek; Bajciova, Viera; Broz, Martin; Tinka, Pavel; Jezova, Marta; Palova, Hana; Kren, Leos; Valik, Dalibor; Slaby, Ondrej; Sterba, Jaroslav Share Save
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Targeted treatment of severe vascular malformations harboring PIK3CA and TEK mutations with alpelisib is highly effective with limited toxicity Sterba, Martin; Pokorna, Petra; Faberova, Renata; Pinkova, Blanka; Skotakova, Jarmila; Seehofnerova, Anna; Blatny, Jan; Janigova, Lucia; Koskova, Olga; Palova, Hana; Mahdal, Michal; Pazourek, Lukas; Jabandziev, Petr; Slaby, Ondrej; Mudry, Peter; Sterba, Jaroslav Share Save
THE LANDSCAPE OF TUMOR CELL STATES AND SPATIAL ORGANIZATION IN H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA ACROSS AGE AND LOCATION Liu, Ilon; Jiang, Li; Samuelsson, Erik; Salas, Sergio Marco; Beck, Alexander; Hack, Olivia; Jeong, Daeun; Shaw, McKenzie; Englinger, Bernhard; LaBelle, Jenna; Mire, Hafsa; Madlener, Sibylle; Mayr, Lisa; Quezada, Michael; Trissal, Maria; Panditharatna, Eshini; Ernst, Kati; Vogelzang, Jayne; Gatesman, Taylor; Halbert, Matthew; Palova, Hana; Vesela, Petra; Sterba, Jaroslav; Slaby, Ondrej; Geyeregger, Rene; Diaz, Aaron; Findlay, Izac; Dun, Matt; Resnick, Adam; Suva, Mario; Jones, David; Agnihotri, Sameer; Ostlin, Jessica; Koschmann, Carl; Haberler, Christine; Czech, Thomas; Slavc, Irene; Cotter, Jennifer; Ligon, Keith; Alexandrescu, Sanda; Yung, W. K. Alfred; Arrillaga-Romany, Isabel; Gojo, Johannes; Monje, Michelle; Nilsson, Mats; Filbin, Mariella Share Save
CLINICAL RESPONSE TO THE PDGFRA/KIT INHIBITOR AVAPRITINIB IN PEDIATRIC AND YOUNG ADULT HIGH-GRADE GLIOMA PATIENTS WITH H3K27M OR PDGFRA GENOMIC ALTERATIONS Trissal, Maria; Mayr, Lisa; Schwark, Kallen; LaBelle, Jenna; Kong, Seongbae; Furtner, Julia; Weiler-Wichtl, Liesa; Supko, Jeffrey; Rozowsky, Jacob; Hack, Olivia; Groves, Andrew; Marques, Joana; Leiss, Ulrike; Rosenmayr, Verena; Dubois, Frank; Greenwald, Noah F.; Madlener, Sibylle; Guntner, Armin Sebastian; Palova, Hana; Stepien, Natalia; Lotsch-Gojo, Daniela; Dorfer, Christian; Dieckmann, Karen; Peyrl, Andreas; Azizi, Amadeo A.; Baumgartner, Alicia; Slaby, Ondrej; Pokorna, Petra; Bandopadhayay, Pratiti; Beroukhim, Rameen; Ligon, Keith L.; Kramm, Christof M.; Bronsema, Annika; Bailey, Simon; Stucklin, Ana Guerreiro; Mueller, Sabine Mueller; Jones, David T. W.; Jager, Natalie; Mullauer, Leonhard; Haberler, Christine; Kumar-Sinha, Chandan; Chinnaiyan, Arul; Mody, Rajen; Sterba, Jaroslav; Skrypek, Mary; Martinez, Nina; Bowers, Daniel C.; Koschmann, Carl Koschmann; Gojo, Johannes; Filbin, Mariella Share Save
Clinical response to the PDGFRα inhibitor avapritinib in high-grade glioma patients Mayr, Lisa; Trissal, Maria; Schwark, Kallen; Labelle, Jenna; Groves, Andrew; Furtner-Srajer, Julia; Supko, Jeffrey; Weiler-Wichtl, Liesa; Hack, Olivia; Rozowsky, Jacob; Marques, Joana G.; Pandatharatna, Eshini; Leiss, Ulrike; Rosenmayr, Verena; Dubois, Frank; Greenwald, Noah F.; Madlener, Sibylle; Guntner, Armin S.; Palova, Hana; Stepien, Natalia; Lotsch-Gojo, Daniela; Dorfer, Christian; Dieckmann, Karin; Peyrl, Andreas; Azizi, Amedeo A.; Baumgartner, Alicia; Slaby, Ondrej; Pokorna, Petra; Bandopadhayay, Pratiti; Beroukhim, Rameen; Ligon, Keith; Kramm, Christof; Bronsema, Annika; Bailey, Simon; Stucklin, Ana Guerreiro; Mueller, Sabine; Jones, David T.; Jager, Natalie; Sterba, Jaroslav; Mullauer, Leonhard; Haberler, Christine; Kumar-Sinha, Chandan; Chinnaiyan, Arul; Mody, Rajen; Skrypek, Mary; Martinez, Nina; Bowers, Daniel C.; Koschmann, Carl; Gojo, Johannes; Filbin, Mariella Share Save
Precision medicine and cancer drug repurposing in the management of vascular anomalies Pokorna, Petra; Faberova, Renata; Koskova, Olga; Sterba, Martin; Palova, Hana; Kozelkova, Katerina; Jugas, Robin; Al Tukmachi, Dagmar; Machackova, Tana; Sana, Jiri; Mudry, Peter; Sterba, Jaroslav; Slaby, Ondrej Share Save
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