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SaveA Phase Ia/b study of MEK1/2 inhibitor binimetinib with MET inhibitor crizotinib in patients with RAS mutant advanced colorectal cancer (MErCuRIC)
Aroldi, Francesca; Elez, Elena; Andre, Thierry; Perkins, Geraldine; Prenen, Hans; Popovici, Vlad; Gallagher, Peter; Houlden, Jennifer; Collins, Linda; Roberts, Corran; Rolfo, Christian; Di Nicolantonio, Federica; Grayson, Margaret; Boyd, Ruth; Bettens, Karolien; Delfavero, Jurgen; Coyle, Victoria; Lawler, Mark; Khawaja, Hajrah; Laurent-Puig, Pierre; Salto-Tellez, Manuel; Maughan, Tim S.; Tabernero, Josep; Adams, Richard; Jones, Robert; Hennessy, Bryan T.; Bardelli, Alberto; Peeters, Marc; Middleton, Mark R.; Wilson, Richard H.; Van Schaeybroeck, Sandra Share Save Share Save BRAF plus EGFR plus /- MEK inhibitors after immune checkpoint inhibitors in BRAF V600E mutated and deficient mismatch repair or microsatellite instability high metastatic colorectal cancerAmbrosini, Margherita; Tougeron, David; Modest, Dominik; Guimbaud, Rosine; Kopetz, Scott; Decraecker, Marie; Kim, Stefano; Coutzac, Clelia; Perkins, Geraldine; Alouani, Emily; Marmorino, Federica; Pernot, Simon; Sinicrope, Frank A.; Elez, Elena; Parent, Pauline; Cremolini, Chiara; Pietrantonio, Filippo; Lonardi, Sara; Gallois, Claire; Taieb, Julien Share Save Efficacy and safety of the combination of encorafenib/cetuximab with or without binimetinib in patients with BRAF V600E-mutated metastatic colorectal cancer: an AGEO real-world multicenter studyGallois, C.; Bergen, E. S.; Auclin, E.; Pernot, S.; Higue, J.; Trouilloud, I.; Touchefeu, Y.; Turpin, A.; Mazard, T.; Sartore-Bianchi, A.; Prenen, H.; Alberti, A.; Pilla, L.; Cuissy, S.; Wookey, V.; Perret, A.; Melchior, C.; Artru, P.; Dubreuil, O.; Drouillard, A.; Doat, S.; Lavole, J.; Basile, D.; Perkins, G.; Jary, M.; Stintzing, S.; Jos, J.; Tougeron, D.; Taieb, J. Share Save Ampullary tumors: French Intergroup Clinical Practice Guidelines for diagnosis, treatments and follow-up (TNCD, SNFGE, FFCD, UNICANCER, GERCOR, SFCD, SFED, ACHBT, AFC, SFRO, RENAPE, SNFCP, AFEF, SFP, SFR)Hautefeuille, Vincent; Williet, Nicolas; Turpin, Anthony; Napoleon, Bertrand; Dupre, Aurelien; Huguet, Florence; Bignon, Anne Laure; Camus, Marine; Chevaux, Jean-Baptiste; Coriat, Romain; Cros, Jerome; Edeline, Julien; Koch, Stephane; Neuzillet, Cindy; Perkins, Geraldine; Regimbeau, Jean Marc; Sefrioui, David; Vitellius, Carole; Vullierme, Marie-Pierre; Bouche, Olivier; Gaujoux, Sebastien Share Save A multicenter study evaluating efficacy of immune checkpoint inhibitors in advanced non-colorectal digestive cancers with microsatellite instabilityMoreau, Mathilde; Alouani, Emily; Flecchia, Clemence; Falcoz, Antoine; Gallois, Claire; Auclin, Edouard; Andre, Thierry; Cohen, Romain; Hollebecque, Antoine; Turpin, Anthony; Pernot, Simon; Masson, Therese; Di Fiore, Frederic; Dutherge, Marie; Mazard, Thibault; Hautefeuille, Vincent; Van Laethem, Jean-Luc; De la Fouchardiere, Christelle; Perkins, Geraldine; Ben-Abdelghani, Meher; Sclafani, Francesco; Aparicio, Thomas; Kim, Stefano; Vernerey, Dewi; Taieb, Julien; Guimbaud, Rosine; Tougeron, David Share Save Features of colorectal adenomas among young patients with Lynch syndrome according to path_MMR: Results from the PRED-IdF registryAlric, Hadrien; Coffin, Elise; Lekhal, Celine; Benusiglio, Patrick R.; Dhooge, Marion; Colas, Chrystelle; Caron, Olivier; Cusin, Veronica; Becq, Aymeric; Robles, Enrique Perez Cuadrado; Leenhardt, Romain; Perkins, Geraldine; Buecher, Bruno; Bellanger, Jerome; Rahmi, Gabriel; Malka, David; Laurent-Puig, Pierre; Chaussade, Stanislas; Benamouzig, Robert; Parc, Yann; Cellier, Christophe; Perrod, Guillaume Share Save Primary resistance to immunotherapy in patients with a dMMR/MSI metastatic gastrointestinal cancer: who is at risk? An AGEO real-world studyFlecchia, Clemence; Auclin, Edouard; Alouani, Emily; Mercier, Mathilde; Hollebecque, Antoine; Turpin, Anthony; Mazard, Thibault; Pernot, Simon; Dutherage, Marie; Cohen, Romain; Borg, Christophe; Hautefeuille, Vincent; Sclafani, Francesco; Ben-Abdelghani, Meher; Aparicio, Thomas; De La Fouchardiere, Christelle; Herve, Camille; Perkins, Geraldine; Heinrich, Kathrin; Kunzmann, Volker; Gallois, Claire; Guimbaud, Rosine; Tougeron, David; Taieb, Julien Share Save Efficacy of immunotherapy in mismatch repair-deficient advanced colorectal cancer in routine clinical practice. An AGEO studyAlouani, E.; Mercier, M.; Flecchia, C.; Auclin, E.; Hollebecque, A.; Mazard, T.; Turpin, A.; Pernot, S.; Cohen, R.; Dutherage, M.; Kim, S.; Sclafani, F.; Ben-Abdelghani, M.; Herve, C.; Aparicio, T.; De La Fouchardiere, C.; Perkins, G.; Hautefeuille, V.; Jaffrelot, M.; Gallois, C.; Bongard, V.; Tougeron, D.; Taieb, J.; Guimbaud, R. Share Save Lynch syndrome: influence of additional susceptibility variants on cancer riskVibert, Roseline; Hasnaoui, Jasmine; Perrier, Alexandre; Lefebvre, Alexandra; Colas, Chrystelle; Dhooge, Marion; Basset, Noemie; Chansavang, Albain; Desseignes, Camille; Duval, Alex; Farelly, Solenne; Hamzaoui, Nadim; Laurent-Puig, Pierre; Metras, Julie; Moliere, Diane; Muleris, Martine; Netter, Jeanne; Touat, Mehdi; Bielle, Franck; Labreche, Karim; Nicolle, Romain; Perkins, Geraldine; Warcoin, Mathilde; Coulet, Florence; Benusiglio, Patrick R. Share Save Feasibility of high-throughput sequencing in clinical routine cancer care: lessons from the cancer pilot project of the France Genomic Medicine 2025 planAuzanneau, Celine; Bacq, Delphine; Bellera, Carine; Blons, Helene; Boland, Anne; Boucheix, Marlene; Bourdon, Aurelien; Chollet, Emmanuelle; Chomienne, Christine; Deleuze, Jean-Francois; Delmas, Christelle; Dinart, Derek; Esperou, Helene; Geillon, Flore; Geneste, Damien; Italiano, Antoine; Jean, Delphine; Khalifa, Emmanuel; Laizet, Yec'han; Laurent-Puig, Pierre; Lethimonnier, Franck; Levy-Marchal, Claire; Lucchesi, Carlo; Malle, Carine; Mancini, Pierre; Mathoulin-Pelissier, Simone; Meyer, Vincent; Marie-Ange, Palomares; Perkins, Geraldine; Sellan-Albert, Sabrina; Soubeyran, Isabelle; Wallet, Cedric Share Save Can we classify ampullary tumours better? Clinical, pathological and molecular features. Results of an AGEO studyPerkins, Geraldine; Svrcek, Magali; Bouchet-Doumenq, Cecile; Voron, Thibault; Colussi, Orianne; Debove, Clotilde; Merabtene, Fatiha; Dumont, Sylvie; Sauvanet, Alain; Hammel, Pascal; Cros, Jerome; Andre, Thierry; Bachet, Jean-Baptiste; Bardier, Armelle; Douard, Richard; Meatchi, Tchao; Peschaud, Frederique; Emile, Jean-Francois; Cojean-Zelek, Isabelle; Laurent-Puig, Pierre; Taieb, Julien Share Save Vemurafenib and cobimetinib overcome resistance to vemurafenib in BRAF-mutant gangliogliomaTouat, Mehdi; Gratieux, Julie; Auliac, Stephanie Condette; Sejean, Karine; Aldea, Sorin; Savatovsky, Julien; Perkins, Geraldine; Blons, Helene; Ligon, Keith L.; Idbaih, Ahmed; Hollebecque, Antoine; Gimenez-Roqueplo, Anne-Paule; Laurent-Puig, Pierre; Sanson, Marc; Villa, Chiara; Di Stefano, Anna Luisa Share Save Impact of an optimized colonoscopic screening program for patients with Lynch syndrome: 6-year results of a specialized French networkPerrod, Guillaume; Samaha, Elia; Rahmi, Gabriel; Khater, Sherine; Abbes, Leila; Savale, Camille; Perkins, Geraldine; Zaanan, Aziz; Chatellier, Gilles; Malamut, Georgia; Cellier, Christophe Share Save Early Evaluation of Circulating Tumor DNA as Marker of Therapeutic Efficacy in Metastatic Colorectal Cancer Patients (PLACOL Study)Garlan, Fanny; Laurent-Puig, Pierre; Sefrioui, David; Siauve, Nathalie; Didelot, Audrey; Sarafan-Vasseur, Nasrin; Michel, Pierre; Perkins, Geraldine; Mulot, Claire; Blons, Helene; Taieb, Julien; Di Fiore, Frederic; Taly, Valerie; Zaanan, Aziz Share Save Adjuvant FOLFOX plus /- cetuximab in full RAS and BRAF wildtype stage III colon cancer patientsTaieb, J.; Balogoun, R.; Le Malicot, K.; Tabernero, J.; Mini, E.; Folprecht, G.; Van Laethem, J. -L.; Emile, J. -F.; Mulot, C.; Fratte, S.; Levache, C. -B.; Saban-Roche, L.; Thaler, J.; Petersen, L. N.; Bridgewater, J.; Perkins, G.; Lepage, C.; Van Cutsem, E.; Zaanan, A.; Laurent-Puig, P. Share Save Share Save Whole exome sequencing (WES) and RNA sequencing (RNA-seq) in routine clinical practice for colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) patients (pts)Perkins, G.; Fabre, E.; Fallet, V.; Blons, H.; Pecuchet, N.; Gounant, V.; Gibault, L.; Michel-Jeljeli, E.; Antoine, M.; Roux, E.; Wislez, M.; Le Corre, D.; Leroy, K.; Lacave, R.; Taieb, J.; Cadranel, J.; Laurent-Puig, P. Share Save Adjuvant FOLFOX plus cetuximab vs FOLFOX in full RAS and BRAF wild type stage III colon cancer patients: Results from the PETACC8 trialTaieb, J.; Le Malicot, K.; Balogoum, R.; Tabernero, J.; Mini, E.; Folprecht, G.; van Laethem, J-L.; Emile, J-F.; Mulot, C.; Fratte, S.; Levache, C-B.; Saban-Roche, L.; Thaler, J.; Petersen, L. Norgard; Sanchez, E.; Bridgewater, J.; Perkins, G.; Lepage, C.; Zaanan, A.; Laurent-Puig, P. Share Save 
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