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SaveShare Save Thrombospondin-1 is an endogenous substrate of cereblon responsible for immunomodulatory drug-induced thromboembolism
Hatakeyama, Kiwamu; Kikushige, Yoshikane; Ishihara, Daisuke; Yamamoto, Shunsuke; Kawano, Gentaro; Tochigi, Taro; Miyamoto, Toshihiro; Sakoda, Teppei; Christoforou, Andy; Kunisaki, Yuya; Fukata, Mitsuhiro; Kato, Koji; Ito, Takumi; Handa, Hiroshi; Akashi, Koichi Share Save IMiD/CELMoD-induced growth suppression of adult T-cell leukemia/lymphoma cells via cereblon through downregulation of target proteins and their downstream effectorsWang, Yu; Shimosaki, Shunsuke; Ikebe, Emi; Iha, Hidekatsu; Yamamoto, Jun-ichi; Fife, Nichole; Ichikawa, Tomonaga; Hori, Mitsuo; Ogata, Masao; Tsukamoto, Yoshiyuki; Hijiya, Naoki; Moriyama, Masatsugu; Hagiwara, Shotaro; Kusano, Shuichi; Saito, Masumichi; Ahmed, Kamruddin; Nishizono, Akira; Handa, Hiroshi; Morishita, Kazuhiro Share Save A prospective, multicenter, observational study of ixazomib plus lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma in JapanHorigome, Yuichi; Iino, Masaki; Harazaki, Yoriko; Kobayashi, Takahiro; Handa, Hiroshi; Hiramatsu, Yasushi; Kuroi, Taiga; Tanimoto, Kazuki; Matsue, Kosei; Abe, Masahiro; Ishida, Tadao; Ito, Shigeki; Iwasaki, Hiromi; Kuroda, Junya; Shibayama, Hirohiko; Sunami, Kazutaka; Takamatsu, Hiroyuki; Tamura, Hideto; Hayashi, Toshiaki; Akagi, Kiwamu; Maeda, Takahiro; Yoshida, Takahiro; Mori, Ikuo; Shinozaki, Tomohiro; Iida, Shinsuke Share Save Share Save Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cellsOshima, S; Nakamura, T; Namiki, S; Okada, E; Tsuchiya, K; Okamoto, R; Yamazaki, M; Yokota, T; Aida, M; Yamaguchi, Y; Kanai, T; Handa, H; Watanabe, M Share Save Share Save Drosophila blimp-1 is a transient transcriptional repressor that controls timing of the ecdysone-induced developmental pathwayAgawa, Yasuo; Sarhan, Moustafa; Kageyama, Yuji; Akagi, Kazutaka; Takai, Masayoshi; Hashiyama, Kazuya; Wada, Tadashi; Handa, Hiroshi; Iwamatsu, Akihiro; Hirose, Susumu; Ueda, Hitoshi Share Save Human transcription elongation factor NELF: Identification of novel subunits and reconstitution of the functionally active complexNarita, T; Yamaguchi, Y; Yano, K; Sugimoto, S; Chanarat, S; Wada, T; Kim, DK; Hasegawa, J; Omori, M; Inukai, N; Endoh, M; Yamada, T; Handa, H Share Save Share Save Share Save Share Save Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemiaUrano, A; Endoh, M; Wada, T; Morikawa, Y; Itoh, M; Kataoka, Y; Taki, T; Akazawa, H; Nakajima, H; Komuro, I; Yoshida, N; Hayashi, Y; Handa, H; Kitamura, T; Nosaka, T Share Save Share Save Human Spt6 stimulates transcription elongation by RNA polymerase II in vitroEndoh, M; Zhu, WY; Hasegawa, J; Watanabe, H; Kim, DK; Aida, M; Inukai, N; Narita, T; Yamada, T; Furuya, A; Sato, H; Yamaguchi, Y; Mandal, SS; Remberg, D; Wada, T; Handa, H Share Save Share Save Share Save Share Save Share Save 
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