Not logged inA PI3Kd-Foxo1-FasL signaling amplification loop rewires CD4+T helper cell signaling, differentiation and epigenetic remodeling
Golec, Dominic P.; Gazzinelli-Guimaraes, Pedro; Chauss, Daniel; Nagashima, Hiroyuki; Yu, Kang; Hill, Tom; Cannons, Jennifer L.; Perry, Jillian; Joshi, Ilin; Pereira, Nicolas; Silva Oliveira, Fabricio Marcus; Cruz, Anthony C.; Druey, Kirk M.; Lack, Justin B.; Nutman, Thomas B.; Villarino, Alejandro V.; O'Shea, John J.; Afzali, Behdad; Schwartzberg, Pamela L. .png)
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SaveA deep intronic splice-altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusionOchoa, Sebastian; Hsu, Amy P.; Oler, Andrew J.; Kumar, Dhaneshwar; Chauss, Daniel; van Hamburg, Jan Piet; van Laar, Gustaaf G.; Oikonomou, Vasileios; Ganesan, Sundar; Ferre, Elise M. N.; Schmitt, Monica M.; Dimaggio, Tom; Barber, Princess; Constantine, Gregory M.; Rosen, Lindsey B.; Auwaerter, Paul G.; Gandhi, Bhumika; Miller, Jennifer L.; Eisenberg, Rachel; Rubinstein, Arye; Schussler, Edith; Balliu, Erjola; Shashi, Vandana; Neth, Olaf; Olbrich, Peter; Le, Kim My; Mamia, Nanni; Laakso, Saila; Nevalainen, Pasi I.; Groenholm, Juha; Seppaenen, Mikko R. J.; Boon, Louis; Uzel, Gulbu; Franco, Luis M.; Heller, Theo; Winer, Karen K.; Ghosh, Rajarshi; Seifert, Bryce A.; Walkiewicz, Magdalena; Notarangelo, Luigi D.; Zhou, Qing; Askentijevich, Ivona; Gahl, William; Dalgard, Cliffton L.; Perera, Lalith; Afzali, Behdad; Tas, Sander W.; Holland, Steven M.; Lionakis, Michail S. Share Save Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous systemGao, Yuanyuan; Wang, Yan; Chauss, Daniel; Villarino, Alejandro V.; Link, Verena M.; Nagashima, Hiroyuki; Spinner, Camille A.; Koparde, Vishal N.; Bouladoux, Nicolas; Abers, Michael S.; Break, Timothy J.; Chopp, Laura B.; Park, Jung-Hyun; Zhu, Jinfang; Wiest, David L.; Leonard, Warren J.; Lionakis, Michail S.; O'Shea, John J.; Afzali, Behdad; Belkaid, Yasmine; Lazarevic, Vanja Share Save Share Save Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cellsSahu, Ranjit K.; Xavier, Sandhya; Chauss, Daniel; Wang, Luopin; Chew, Claude; Taylor, Ronald; Stallcup, William B.; Ma, Jennie Z.; Kazemian, Majid; Afzali, Behdad; Kohl, Jorg; Portilla, Didier Share Save Complement activates an autocrine Vitamin D system that recruits a defined transcription factor network to shut down pro-inflammatory programs of Th1 cellsChauss, Daniel C.; Freiwald, Tilo; McGregor, Reuben; Yan, Bingyu; Wang, Luopin; Nova-Lamperti, Estafania; Kumar, Dhaneshwar; Zhang, Zonghao; Teague, Heather; West, Erin; Vannella, Kevin M.; Ramos-Benitez, Marcos J.; Bibby, Jack; Kelly, Audrey; Malik, Amna; Freeman, Alexandra F.; Schwartz, Daniella M.; Portilla, Didier; Chertow, Daniel S.; John, Susan; Lavender, Paul; Kemper, Claudia; Lombardi, Giovanna; Mehta, Nehal N.; Cooper, Nichola; Lionakis, Michail S.; Laurence, Arian; Kazemian, Majid; Afzali, Behdad Share Save Share Save Share Save Reply to Grigoriev et al., Sequences of SARS-CoV-2 'Hybrids' with the Human Genome: Signs of Non-coding RNA?Yan, Bingyu; Chakravorty, Srishti; Mirabelli, Carmen; Wang, Luopin; Trujillo-Ochoa, Jorge L.; Chauss, Daniel; Kumar, Dhaneshwar; Lionakis, Michail S.; Olson, Matthew R.; Wobus, Christiane E.; Afzali, Behdad; Kazemian, Majid Share Save Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cellsChauss, Daniel; Freiwald, Tilo; McGregor, Reuben; Yan, Bingyu; Wang, Luopin; Nova-Lamperti, Estefania; Kumar, Dhaneshwar; Zhang, Zonghao; Teague, Heather; West, Erin E.; Vannella, Kevin M.; Ramos-Benitez, Marcos J.; Bibby, Jack; Kelly, Audrey; Malik, Amna; Freeman, Alexandra F.; Schwartz, Daniella M.; Portilla, Didier; Chertow, Daniel S.; John, Susan; Lavender, Paul; Kemper, Claudia; Lombardi, Giovanna; Mehta, Nehal N.; Cooper, Nichola; Lionakis, Michail S.; Laurence, Arian; Kazemian, Majid; Afzali, Behdad Share Save Response to Comments on Aberrant type 1 immunity drives susceptibility to mucosal fungal infectionsBreak, Timothy J.; Oikonomou, Vasileios; Dutzan, Nicolas; Desai, Jigar V.; Swidergall, Marc; Freiwald, Tilo; Chauss, Daniel; Harrison, Oliver J.; Alejo, Julie; Williams, Drake W.; Pittaluga, Stefania; Lee, Chyi-Chia R.; Bouladoux, Nicolas; Swamydas, Muthulekha; Hoffman, Kevin W.; Greenwell-Wild, Teresa; Bruno, Vincent M.; Rosen, Lindsey B.; Lwin, Wint; Renteria, Andy; Pontejo, Sergio M.; Shannon, John P.; Myles, Ian A.; Olbrich, Peter; Ferre, Elise M. N.; Schmitt, Monica; Martin, Daniel; Barber, Daniel L.; Solis, Norma V.; Notarangelo, Luigi D.; Serreze, David V.; Matsumoto, Mitsuru; Hickman, Heather D.; Murphy, Philip M.; Anderson, Mark S.; Lim, Jean K.; Holland, Steven M.; Filler, Scott G.; Afzali, Behdad; Belkaid, Yasmine; Moutsopoulos, Niki M.; Lionakis, Michail S. Share Save Host-Virus Chimeric Events in SARS-CoV-2-Infected Cells Are Infrequent and ArtifactualYan, Bingyu; Chakravorty, Srishti; Mirabelli, Carmen; Wang, Luopin; Trujillo-Ochoa, Jorge L.; Chauss, Daniel; Kumar, Dhaneshwar; Lionakis, Michail S.; Olson, Matthew R.; Wobus, Christiane E.; Afzali, Behdad; Kazemian, Majid Share Save Share Save SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivationYan, Bingyu; Freiwald, Tilo; Chauss, Daniel; Wang, Luopin; West, Erin; Mirabelli, Carmen; Zhang, Charles J.; Nichols, Eva-Maria; Malik, Nazish; Gregory, Richard; Bantscheff, Marcus; Ghidelli-Disse, Sonja; Kolev, Martin; Frum, Tristan; Spence, Jason R.; Sexton, Jonathan Z.; Alysandratos, Konstantinos D.; Kotton, Darrell N.; Pittaluga, Stefania; Bibby, Jack; Niyonzima, Nathalie; Olson, Matthew R.; Kordasti, Shahram; Portilla, Didier; Wobus, Christiane E.; Laurence, Arian; Lionakis, Michail S.; Kemper, Claudia; Afzali, Behdad; Kazemian, Majid Share Save BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells (vol 22, pg 370, 2021)Yao, Chen; Lou, Guohua; Sun, Hong-Wei; Zhu, Ziang; Sun, Yi; Chen, Zeyu; Chauss, Daniel; Moseman, E. Ashley; Cheng, Jun; D'Antonio, Marc A.; Shi, Wangke; Shi, Junwei; Kometani, Kohei; Kurosaki, Tomohiro; Wherry, E. John; Afzali, Behdad; Gattinoni, Luca; Zhu, Yuwen; McGavern, Dorian B.; O'Shea, John J.; Schwartzberg, Pamela L.; Wu, Tuoqi Share Save BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cellsYao, Chen; Lou, Guohua; Sun, Hong-Wei; Zhu, Ziang; Sun, Yi; Chen, Zeyu; Chauss, Daniel; Moseman, E. Ashley; Cheng, Jun; D'Antonio, Marc A.; Shi, Wangke; Shi, Junwei; Kometani, Kohei; Kurosaki, Tomohiro; Wherry, E. John; Afzali, Behdad; Gattinoni, Luca; Zhu, Yuwen; McGavern, Dorian B.; O'Shea, John J.; Schwartzberg, Pamela L.; Wu, Tuoqi Share Save Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune CellsKolev, Martin; West, Erin E.; Kunz, Natalia; Chauss, Daniel; Moseman, E. Ashley; Rahman, Jubayer; Freiwald, Tilo; Balmer, Maria L.; Lotscher, Jonas; Dimeloe, Sarah; Rosser, Elizabeth C.; Wedderburn, Lucy R.; Mayer-Barber, Katrin D.; Bohrer, Andrea; Lavender, Paul; Cope, Andrew; Wang, Luopin; Kaplan, Mariana J.; Moutsopoulos, Niki M.; McGavern, Dorian; Holland, Steven M.; Hess, Christoph; Kazemian, Majid; Afzali, Behdad; Kemper, Claudia Share Save Integrated Pan-Cancer Map of EBV-Associated Neoplasms Reveals Functional Host-Virus InteractionsChakravorty, Srishti; Yan, Bingyu; Wang, Chong; Wang, Luopin; Quaid, Joseph Taylor; Lin, Chin Fang; Briggs, Scott D.; Majumder, Joydeb; Canaria, D. Alejandro; Chauss, Daniel; Chopra, Gaurav; Olson, Matthew R.; Zhao, Bo; Afzali, Behdad; Kazemian, Majid Share Save Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosaPovoleri, Giovanni A. M.; Nova-Lamperti, Estefania; Scotta, Cristiano; Fanelli, Giorgia; Chen, Yun-Ching; Becker, Pablo D.; Boardman, Dominic; Costantini, Benedetta; Romano, Marco; Pavlidis, Polychronis; McGregor, Reuben; Pantazi, Eirini; Chauss, Daniel; Sun, Hong-Wei; Shih, Han-Yu; Cousins, David J.; Cooper, Nichola; Powell, Nick; Kemper, Claudia; Pirooznia, Mehdi; Laurence, Arian; Kordasti, Shahram; Kazemian, Majid; Lombardi, Giovanna; Afzali, Behdad Share Save Share Save 
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