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Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects Kasela, Silva; Aguet, Francois; Kim-Hellmuth, Sarah; Brown, Brielin C.; Nachun, Daniel C.; Tracy, Russell P.; Durda, Peter; Liu, Yongmei; Taylor, Kent D.; Johnson, W. Craig; Berg, David Van Den; Gabriel, Stacey; Gupta, Namrata; Smith, Joshua D.; Blackwell, Thomas W.; Rotter, Jerome I.; Ardlie, Kristin G.; Manichaikul, Ani; Rich, Stephen S.; Barr, R. Graham; Lappalainen, Tuuli Share Save
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The role of depression and antidepressant treatment in antihypertensive medication adherence and persistence: Utilising electronic health record data Kariis, Hanna Maria; Kasela, Silva; Jurgenson, Tuuli; Saar, Aet; Lass, Jana; Krebs, Kristi; Vosa, Urmo; Haan, Elis; Milani, Lili; Lehto, Kelli Share Save
The functional impact of rare variation across the regulatory cascade Li, Taibo; Ferraro, Nicole; Strober, Benjamin J.; Aguet, Francois; Kasela, Silva; Arvanitis, Marios; Ni, Bohan; Wiel, Laurens; Hershberg, Elliot; Ardlie, Kristin; Arking, Dan E.; Beer, Rebecca L.; Brody, Jennifer; Blackwell, Thomas W.; Clish, Clary; Gabriel, Stacey; Gerszten, Robert; Guo, Xiuqing; Gupta, Namrata; Johnson, W. Craig; Lappalainen, Tuuli; Lin, Henry J.; Liu, Yongmei; Nickerson, Deborah A.; Papanicolaou, George; Pritchard, Jonathan K.; Qasba, Pankaj; Shojaie, Ali; Smith, Josh; Sotoodehnia, Nona; Taylor, Kent D.; Tracy, Russell P.; Van den Berg, David; Wheeler, Matthew T.; Rich, Stephen S.; Rotter, Jerome I.; Battle, Alexis; Montgomery, Stephen B. Share Save
Multiset correlation and factor analysis enables exploration of multi-omics data Brown, Brielin C.; Wang, Collin; Kasela, Silva; Aguet, Francois; Nachun, Daniel C.; Taylor, Kent D.; Tracy, Russell P.; Durda, Peter; Liu, Yongmei; Johnson, W. Craig; Van Den Berg, David; Gupta, Namrata; Gabriel, Stacy; Smith, Joshua D.; Gerzsten, Robert; Clish, Clary; Wong, Quenna; Papanicolau, George; Blackwell, Thomas W.; Rotter, Jerome I.; Rich, Stephen S.; Barr, R. Graham; Ardlie, Kristin G.; Knowles, David A.; Lappalainen, Tuuli Share Save
Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countries Shen, Qing; Mikkelsen, Dorte Helenius; Luitva, Laura Birgit; Song, Huan; Kasela, Silva; Aspelund, Thor; Bergstedt, Jacob; Lu, Yi; Sullivan, Patrick F.; Ye, Weimin; Fall, Katja; Tornvall, Per; Pawitan, Yudi; Andreassen, Ole A.; Buil, Alfonso; Milani, Lili; Fang, Fang; Valdimarsdottir, Unnur Share Save
Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans Angelini, Elsa D.; Yang, Jie; Balte, Pallavi P.; Hoffman, Eric A.; Manichaikul, Ani W.; Sun, Yifei; Shen, Wei; Austin, John H. M.; Allen, Norrina B.; Bleecker, Eugene R.; Bowler, Russell; Cho, Michael H.; Cooper, Christopher S.; Couper, David; Dransfield, Mark T.; Garcia, Christine Kim; Han, MeiLan K.; Hansel, Nadia N.; Hughes, Emlyn; Jacobs, David R.; Kasela, Silva; Kaufman, Joel Daniel; Kim, John Shinn; Lappalainen, Tuuli; Lima, Joao; Malinsky, Daniel; Martinez, Fernando J.; Oelsner, Elizabeth C.; Ortega, Victor E.; Paine, Robert; Post, Wendy; Pottinger, Tess D.; Prince, Martin R.; Rich, Stephen S.; Silverman, Edwin K.; Smith, Benjamin M.; Swift, Andrew J.; Watson, Karol E.; Woodruff, Prescott G.; Laine, Andrew F.; Barr, R. Graham Share Save
Canonical correlation analysis for multi-omics: Application to cross-cohort analysis Jiang, Min-Zhi; Aguet, Francois; Ardlie, Kristin; Chen, Jiawen; Cornell, Elaine; Cruz, Dan; Durda, Peter B.; Gabriel, Stacey E.; Gerszten, Robert; Guo, Xiuqing W.; Johnson, Craig; Kasela, Silva A.; Lange, Leslie; Lappalainen, Tuuli; Liu, Yongmei P.; Reiner, Alex; Smith, Josh; Sofer, Tamar D.; Taylor, Kent P.; Tracy, Russell J.; VanDenBerg, David G.; Wilson, James S.; Rich, Stephen I.; Rotter, Jerome I.; Love, Michael M.; Raffield, Laura; Li, Yun Share Save
Arsenic Exposure, Blood DNA Methylation, and Cardiovascular Disease Domingo-Relloso, Arce; Makhani, Kiran; Riffo-Campos, Angela L.; Tellez-Plaza, Maria; Klein, Kathleen Oros; Subedi, Pooja; Zhao, Jinying; Moon, Katherine A.; Bozack, Anne K.; Haack, Karin; Goessler, Walter; Umans, Jason G.; Best, Lyle G.; Zhang, Ying; Herreros-Martinez, Miguel; Glabonjat, Ronald A.; Schilling, Kathrin; Galvez-Fernandez, Marta; Kent, Jack W., Jr.; Sanchez, Tiffany R.; Taylor, Kent D.; Johnson, W. Craig; Durda, Peter; Tracy, Russell P.; Rotter, Jerome I.; Rich, Stephen S.; Van Den Berg, David; Kasela, Silva; Lappalainen, Tuuli; Vasan, Ramachandran S.; Joehanes, Roby; Howard, Barbara V.; Levy, Daniel; Lohman, Kurt; Liu, Yongmei; Fallin, M. Daniele; Cole, Shelley A.; Mann, Koren K.; Navas-Acien, Ana Share Save
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases Wielscher, Matthias; Mandaviya, Pooja R.; Kuehnel, Brigitte; Joehanes, Roby; Mustafa, Rima; Robinson, Oliver; Zhang, Yan; Bodinier, Barbara; Walton, Esther; Mishra, Pashupati P.; Schlosser, Pascal; Wilson, Rory; Tsai, Pei-Chien; Palaniswamy, Saranya; Marioni, Riccardo E.; Fiorito, Giovanni; Cugliari, Giovanni; Karhunen, Ville; Ghanbari, Mohsen; Psaty, Bruce M.; Loh, Marie; Bis, Joshua C.; Lehne, Benjamin; Sotoodehnia, Nona; Deary, Ian J.; Chadeau-Hyam, Marc; Brody, Jennifer A.; Cardona, Alexia; Selvin, Elizabeth; Smith, Alicia K.; Miller, Andrew H.; Torres, Mylin A.; Marouli, Eirini; Gao, Xin; van Meurs, Joyce B. J.; Graf-Schindler, Johanna; Rathmann, Wolfgang; Koenig, Wolfgang; Peters, Annette; Weninger, Wolfgang; Farlik, Matthias; Zhang, Tao; Chen, Wei; Xia, Yujing; Teumer, Alexander; Nauck, Matthias; Grabe, Hans J.; Doerr, Macus; Lehtimaki, Terho; Guan, Weihua; Milani, Lili; Tanaka, Toshiko; Fisher, Krista; Waite, Lindsay L.; Kasela, Silva; Vineis, Paolo; Verweij, Niek; van der Harst, Pim; Iacoviello, Licia; Sacerdote, Carlotta; Panico, Salvatore; Krogh, Vittorio; Tumino, Rosario; Tzala, Evangelia; Matullo, Giuseppe; Hurme, Mikko A.; Raitakari, Olli T.; Colicino, Elena; Baccarelli, Andrea A.; Kahonen, Mika; Herzig, Karl-Heinz; Li, Shengxu; Conneely, Karen N.; Kooner, Jaspal S.; Kottgen, Anna; Heijmans, Bastiaan T.; Deloukas, Panos; Relton, Caroline; Ong, Ken K.; Bell, Jordana T.; Boerwinkle, Eric; Elliott, Paul; Brenner, Hermann; Beekman, Marian; Levy, Daniel; Waldenberger, Melanie; Chambers, John C.; Dehghan, Abbas; Jarvelin, Marjo-Riitta Share Save
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Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus Tin, Adrienne; Schlosser, Pascal; Matias-Garcia, Pamela R.; Thio, Chris H. L.; Joehanes, Roby; Liu, Hongbo; Yu, Zhi; Weihs, Antoine; Hoppmann, Anselm; Grundner-Culemann, Franziska; Min, Josine L.; Kuhns, Victoria L. Halperin; Adeyemo, Adebowale A.; Agyemang, Charles; arnlov, Johan; Aziz, Nasir A.; Baccarelli, Andrea; Bochud, Murielle; Brenner, Hermann; Bressler, Jan; Breteler, Monique M. B.; Carmeli, Cristian; Chaker, Layal; Coresh, Josef; Corre, Tanguy; Correa, Adolfo; Cox, Simon R.; Delgado, Graciela E.; Eckardt, Kai-Uwe; Ekici, Arif B.; Endlich, Karlhans; Floyd, James S.; Fraszczyk, Eliza; Gao, Xu; Gao, Xin; Gelber, Allan C.; Ghanbari, Mohsen; Ghasemi, Sahar; Gieger, Christian; Greenland, Philip; Grove, Megan L.; Harris, Sarah E.; Hemani, Gibran; Henneman, Peter; Herder, Christian; Horvath, Steve; Hou, Lifang; Hurme, Mikko A.; Hwang, Shih-Jen; Kardia, Sharon L. R.; Kasela, Silva; Kleber, Marcus E.; Koenig, Wolfgang; Kooner, Jaspal S.; Kronenberg, Florian; Kuehnel, Brigitte; Ladd-Acosta, Christine; Lehtimaki, Terho; Lind, Lars; Liu, Dan; Lloyd-Jones, Donald M.; Lorkowski, Stefan; Lu, Ake T.; Marioni, Riccardo E.; Marz, Winfried; McCartney, Daniel L.; Meeks, Karlijn A. C.; Milani, Lili; Mishra, Pashupati P.; Nauck, Matthias; Nowak, Christoph; Peters, Annette; Prokisch, Holger; Psaty, Bruce M.; Raitakari, Olli T.; Ratliff, Scott M.; Reiner, Alex P.; Schottker, Ben; Schwartz, Joel; Sedaghat, Sanaz; Smith, Jennifer A.; Sotoodehnia, Nona; Stocker, Hannah R.; Stringhini, Silvia; Sundstrom, Johan; Swenson, Brenton R.; van Meurs, Joyce B. J.; van Vliet-Ostaptchouk, Jana V.; Venema, Andrea; Volker, Uwe; Winkelmann, Juliane; Wolffenbuttel, Bruce H. R.; Zhao, Wei; Zheng, Yinan; Loh, Marie; Snieder, Harold; Waldenberger, Melanie; Levy, Daniel; Akilesh, Shreeram; Woodward, Owen M.; Susztak, Katalin; Teumer, Alexander; Kottgen, Anna Share Save
Meta-analyses identify DNA methylation associated with kidney function and damage Schlosser, Pascal; Tin, Adrienne; Matias-Garcia, Pamela R.; Thio, Chris H. L.; Joehanes, Roby; Liu, Hongbo; Weihs, Antoine; Yu, Zhi; Hoppmann, Anselm; Grundner-Culemann, Franziska; Min, Josine L.; Adeyemo, Adebowale A.; Agyemang, Charles; Arnlov, Johan; Aziz, Nasir A.; Baccarelli, Andrea; Bochud, Murielle; Brenner, Hermann; Breteler, Monique M. B.; Carmeli, Cristian; Chaker, Layal; Chambers, John C.; Cole, Shelley A.; Coresh, Josef; Corre, Tanguy; Correa, Adolfo; Cox, Simon R.; de Klein, Niek; Delgado, Graciela E.; Domingo-Relloso, Arce; Eckardt, Kai-Uwe; Ekici, Arif B.; Endlich, Karlhans; Evans, Kathryn L.; Floyd, James S.; Fornage, Myriam; Franke, Lude; Fraszczyk, Eliza; Gao, Xu; Gao, Xin; Ghanbari, Mohsen; Ghasemi, Sahar; Gieger, Christian; Greenland, Philip; Grove, Megan L.; Harris, Sarah E.; Hemani, Gibran; Henneman, Peter; Herder, Christian; Horvath, Steve; Hou, Lifang; Hurme, Mikko A.; Hwang, Shih-Jen; Jarvelin, Marjo-Riitta; Kardia, Sharon L. R.; Kasela, Silva; Kleber, Marcus E.; Koenig, Wolfgang; Kooner, Jaspal S.; Kramer, Holly; Kronenberg, Florian; Kuhnel, Brigitte; Lehtimaki, Terho; Lind, Lars; Liu, Dan; Liu, Yongmei; Lloyd-Jones, Donald M.; Lohman, Kurt; Lorkowski, Stefan; Lu, Ake T.; Marioni, Riccardo E.; Marz, Winfried; McCartney, Daniel L.; Meeks, Karlijn A. C.; Milani, Lili; Mishra, Pashupati P.; Nauck, Matthias; Navas-Acien, Ana; Nowak, Christoph; Peters, Annette; Prokisch, Holger; Psaty, Bruce M.; Raitakari, Olli T.; Ratliff, Scott M.; Reiner, Alex P.; Rosas, Sylvia E.; Schottker, Ben; Schwartz, Joel; Sedaghat, Sanaz; Smith, Jennifer A.; Sotoodehnia, Nona; Stocker, Hannah R.; Stringhini, Silvia; Sundstrom, Johan; Swenson, Brenton R.; Tellez-Plaza, Maria; van Meurs, Joyce B. J.; van Vliet-Ostaptchouk, Jana V.; Venema, Andrea; Verweij, Niek; Walker, Rosie M.; Wielscher, Matthias; Winkelmann, Juliane; Wolffenbuttel, Bruce H. R.; Zhao, Wei; Zheng, Yinan; Loh, Marie; Snieder, Harold; Levy, Daniel; Waldenberger, Melanie; Susztak, Katalin; Kottgen, Anna; Teumer, Alexander Share Save
ASSOCIATION BETWEEN DEPRESSION DIAGNOSIS, POLYGENIC RISK FOR DEPRESSION AND ANTIHYPERTENSIVE MEDICATION NON-PERSISTENCE Kariis, Hanna; Kasela, Silva; Jurgenson, Tuuli; Saar, Aet; Lass, Jana; Krebs, Kristi; Vosa, Urmo; Milani, Lili; Lehto, Kelli Share Save
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation Min, Josine L.; Hemani, Gibran; Hannon, Eilis; Dekkers, Koen F.; Castillo-Fernandez, Juan; Luijk, Rene; Carnero-Montoro, Elena; Lawson, Daniel J.; Burrows, Kimberley; Suderman, Matthew; Bretherick, Andrew D.; Richardson, Tom G.; Klughammer, Johanna; Iotchkova, Valentina; Sharp, Gemma; Al Khleifat, Ahmad; Shatunov, Aleksey; Iacoangeli, Alfredo; McArdle, Wendy L.; Ho, Karen M.; Kumar, Ashish; Soderhall, Cilia; Soriano-Tarraga, Carolina; Giralt-Steinhauer, Eva; Kazmi, Nabila; Mason, Dan; McRae, Allan F.; Corcoran, David L.; Sugden, Karen; Kasela, Silva; Cardona, Alexia; Day, Felix R.; Cugliari, Giovanni; Viberti, Clara; Guarrera, Simonetta; Lerro, Michael; Gupta, Richa; Bollepalli, Sailalitha; Mandaviya, Pooja; Zeng, Yanni; Clarke, Toni-Kim; Walker, Rosie M.; Schmoll, Vanessa; Czamara, Darina; Ruiz-Arenas, Carlos; Rezwan, Faisal, I; Marioni, Riccardo E.; Lin, Tian; Awaloff, Yvonne; Germain, Marine; Aissi, Dylan; Zwamborn, Ramona; van Eijk, Kristel; Dekker, Annelot; van Dongen, Jenny; Hottenga, Jouke-Jan; Willemsen, Gonneke; Xu, Cheng-Jian; Barturen, Guillermo; Catala-Moll, Francesc; Kerick, Martin; Wang, Carol; Melton, Phillip; Elliott, Hannah R.; Shin, Jean; Bernard, Manon; Yet, Idil; Smarts, Melissa; Gorrie-Stone, Tyler; Shaw, Chris; Al Chalabi, Ammar; Ring, Susan M.; Pershagen, Goran; Melen, Erik; Jimenez-Conde, Jordi; Roquer, Jaume; Lawlor, Deborah A.; Wright, John; Martin, Nicholas G.; Montgomery, Grant W.; Moffitt, Terrie E.; Poulton, Richie; Esko, Tonu; Milani, Lili; Metspalu, Andres; Perry, John R. B.; Ong, Ken K.; Wareham, Nicholas J.; Matullo, Giuseppe; Sacerdote, Carlotta; Panico, Salvatore; Caspi, Avshalom; Arseneault, Louise; Gagnon, France; Ollikainen, Miina; Kaprio, Jaakko; Felix, Janine F.; Rivadeneira, Fernando; Tiemeier, Henning; van IJzendoorn, Marinus H.; Uitterlinden, Andre G.; Jaddoe, Vincent W. V.; Hale, Chris; McIntosh, Andrew M.; Evans, Kathryn L.; Murray, Alison; Raikkonen, Katri; Lahti, Jari; Nohr, Ellen A.; Sorensen, Thorkild I. A.; Hansen, Torben; Morgen, Camilla S.; Binder, Elisabeth B.; Lucae, Susanne; Gonzalez, Juan Ramon; Bustamante, Mariona; Sunyer, Jordi; Holloway, John W.; Karmaus, Wilfried; Zhang, Hongmei; Deary, Ian J.; Wray, Naomi R.; Starr, John M.; Beekman, Marian; VanHeemst, Diana; Slagboom, P. Eline; Morange, Pierre-Emmanuel; Tregouet, David-Alexandre; Veldink, Jan H.; Davies, Gareth E.; de Geus, Eco J. C.; Boomsma, Dorret, I; Vonk, Judith M.; Brunekreef, Bert; Koppelman, Gerard H.; Alarcon-Riquelme, Marta E.; Huang, Rae-Chi; Pennell, Craig E.; van Meurs, Joyce; Ikram, M. Arfan; Hughes, Alun D.; Tillin, Therese; Chaturvedi, Nish; Pausova, Zdenka; Paus, Tomas; Spector, Timothy D.; Kumari, Meena; Schalkwyk, Leonard C.; Visscher, Peter M.; Smith, George Davey; Bock, Christoph; Gaunt, Tom R.; Bell, Jordana T.; Heijmans, Bastiaan T.; Mill, Jonathan; Relton, Caroline L. Share Save
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression Vosa, Urmo; Claringbould, Annique; Westra, Harm-Jan; Bonder, Marc Jan; Deelen, Patrick; Zeng, Biao; Kirsten, Holger; Saha, Ashis; Kreuzhuber, Roman; Yazar, Seyhan; Brugge, Harm; Oelen, Roy; de Vries, Dylan H.; van der Wijst, Monique G. P.; Kasela, Silva; Pervjakova, Natalia; Alves, Isabel; Fave, Marie-Julie; Agbessi, Mawusse; Christiansen, Mark W.; Jansen, Rick; Seppala, Ilkka; Tong, Lin; Teumer, Alexander; Schramm, Katharina; Hemani, Gibran; Verlouw, Joost; Yaghootkar, Hanieh; Flitman, Reyhan Sonmez; Brown, Andrew; Kukushkina, Viktorija; Kalnapenkis, Anette; Rueger, Sina; Porcu, Eleonora; Kronberg, Jaanika; Kettunen, Johannes; Lee, Bernett; Zhang, Futao; Qi, Ting; Hernandez, Jose Alquicira; Arindrarto, Wibowo; Beutner, Frank; Dmitrieva, Julia; Elansary, Mahmoud; Fairfax, Benjamin P.; Georges, Michel; Heijmans, Bastiaan T.; Hewitt, Alex W.; Kahonen, Mika; Kim, Yungil; Knight, Julian C.; Kovacs, Peter; Krohn, Knut; Li, Shuang; Loeffler, Markus; Marigorta, Urko M.; Mei, Hailang; Momozawa, Yukihide; Mueller-Nurasyid, Martina; Nauck, Matthias; Nivard, Michel G.; Penninx, Brenda W. J. H.; Pritchard, Jonathan K.; Raitakari, Olli T.; Rotzschke, Olaf; Slagboom, Eline P.; Stehouwer, Coen D. A.; Stumvoll, Michael; Sullivan, Patrick; 't Hoen, Peter A. C.; Thiery, Joachim; Tonjes, Anke; van Dongen, Jenny; van Iterson, Maarten; Veldink, Jan H.; Voelker, Uwe; Warmerdam, Robert; Wijmenga, Cisca; Swertz, Morris; Andiappan, Anand; Montgomery, Grant W.; Ripatti, Samuli; Perola, Markus; Kutalik, Zoltan; Dermitzakis, Emmanouil; Bergmann, Sven; Frayling, Timothy; van Meurs, Joyce; Prokisch, Holger; Ahsan, Habibul; Pierce, Brandon L.; Lehtimaki, Terho; Boomsma, Dorret, I; Psaty, Bruce M.; Gharib, Sina A.; Awadalla, Philip; Milani, Lili; Ouwehand, Willem H.; Downes, Kate; Stegle, Oliver; Battle, Alexis; Visscher, Peter M.; Yang, Jian; Scholz, Markus; Powell, Joseph; Gibson, Greg; Esko, Tonu; Franke, Lude Share Save
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