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Spatially Distinct Bone Marrow Sites Are Asymmetrically Impacted by Inflammatory Cardiovascular Disease 空间上不同的骨髓位点受到炎症性心血管疾病的非对称性影响 Deckers, Jeroen; van Elsas, Yuri; Versteeg, Iris; Anbergen, Tom; Toner, Yohana C.; Grao-Roldan, Cristina; Cole, Jennifer E.; Umali, Martin; Wang, William; Nauta, Sheqouia; Demkiw, Krystyna M.; Perez-Medina, Carlos; van Leent, Mandy M. T.; Teunissen, Abraham J. P.; Fayad, Zahi A.; Joosten, Leo A. B.; Swirski, Filip K.; Nahrendorf, Matthias; Divangahi, Maziar; Riksen, Niels P.; Netea, Mihai G.; van der Meel, Roy; Monaco, Claudia; Lutgens, Esther; Beldman, Thijs J.; Mulder, Willem J. M. 分享 收藏
FLASH radiotherapy enables dose escalation resulting in improved survival in an orthotopic muscle-invasive bladder cancer mouse model FLASH放射疗法通过增加剂量实现了在正位肌肉浸润性膀胱癌小鼠模型中的生存改善 Ruan, Jia-Ling; Lee, Carl; Sharma, Osheen; Lovgren, Nathalie; Paillas, Salome; Cooper, Christian; Tullis, Iain D. C.; Giaccia, Amato J.; Kiltie, Anne E.; Petersson, Kristoffer 分享 收藏
Identification of genetic risk loci associated with aquaporin 4-positive neuromyelitis optica spectrum disorder: a genome-wide association study 鉴定与水通道蛋白4阳性视神经脊髓炎谱系障碍相关的遗传风险位点的全基因组关联研究 Attfield, Kathrine E.; Armen, Angelos P.; Kuttikkatte, Subita Balaram; Farooq, Redwan; Francis, Anna G.; Dendrou, Calliope A.; Leite, M. Isabel; Waters, Patrick; Weinshenker, Brian G.; Karczewski, Konrad J.; Neale, Benjamin M.; Jensen, Lise Torp; Rossjohn, Jamie; Gold, Ralf; Korn, Thomas; McVean, Gil; Palace, Jacqueline; Fugger, Lars 分享 收藏
Bowel Urgency in Crohn's Disease: Bridging the Gap Between Patients and Healthcare Providers 克罗恩病中的肠道急迫性:弥合患者与医疗保健提供者之间的差距 Dubinsky, Marla; Bleakman, Alison Potts; Vavricka, Stephan; Travis, Simon; Jairath, Vipul; Panaccione, Remo; Chaparro, Maria; Caron, Benedicte; Fisher, Deborah A.; Moses, Richard; Vadhariya, Aisha; Walsh, Alissa 分享 收藏
Tissue resident memory T cells populate the human uveal tract 组织驻留记忆T细胞分布于人葡萄膜通路 Foers, Andrew D.; Reekie, Ian R.; Wickramasinghe, Lakshanie C.; Ward, Amy; Buckley, Thomas M. W.; Attar, Moustafa; Aguilar-Munoa, Soledad; Pilapil, Queen; Elsayed, Maram E. A. Abdalla; Pledger, Sam; Bhalla, Ananya; Hedley, Robert; Hill, Sarah; Windell, Dylan; Barton, Keith; Masood, Imran; Lim, Kin Sheng; Coles, Mark C.; Sherlock, Jonathan P.; Dick, Andrew D.; Sansom, Stephen N.; Coupland, Sarah E.; Copland, David A.; Buckley, Christopher D.; Sharma, Srilakshmi M. 分享 收藏
Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense 外周位点异质粒细胞生成保障抗菌宿主防御 Silvestre-Roig, Carlos; Chevre, Raphael; Farjia, Merieme; Bender, Alexander; Vocking, Lina M.; Richter, Mathis; Hageb, Ali; Suerdieck, Vincent; Arenas Cerro, Francisco J.; Braster, Quinte; Guzman, Mauricio; Sintes, Jordi; Sharma, Samriti; Lemnitzer, Patricia; Tulotta, Claudia; Borgeling, Yvonne; Herrero-Cervera, Andrea; Flueter, Hannah; Reinartz Groba, Sara Noemi; Ahern, David; Osei-Sarpong, Collins; Zimmer, Ralf; Alonso-Gonzalez, Noelia; Ortega, Eduardo; Lienenklaus, Stefan; Kalinke, Ulrich; Ludwig, Stephan; Engel, Daniel R.; Rosenbauer, Frank; Monaco, Claudia; Dersch, Petra; Kibler, Artur; Cerutti, Andrea; Chavakis, Triantafyllos; Benedito, Rui; Hidalgo, Andres; Jablonska, Jadwiga; Palomino-Segura, Miguel; Soehnlein, Oliver 分享 收藏
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Magnetic resonance enterography to predict disabling disease in newly diagnosed Crohn's disease: the METRIC-EF multivariable prediction model, multicentre diagnostic inception cohort study 磁共振小肠造影预测新诊断克罗恩病的致残性疾病:METRIC-EF多变量预测模型,多中心诊断起始队列研究 Kumar, Shankar; Plumb, Andrew; Mallett, Sue; Clarke, Caroline; Parry, Tom; Weng, Jing Yi Jessica; Bhatnagar, Gauraang; Bloom, Stuart; Hamlin, John; Hart, Ailsa; Travis, Simon; Vega, Roser; Hameed, Maira; Bhagwanani, Anisha; Greenhalgh, Rebecca; Helbren, Emma; Stephenson, James A.; Zealley, Ian; Eze, Vivienne; Franklin, James; Corr, Alison; Gupta, Arun; Isaac, Elizabeth; Tolan, Damian; Hogg, William; Higginson, Antony; Cicchetti, Michela; Gupta, Sunita; Serran, Miguel; Raine, Tim; Ahmed, Mohamed; Brezina, Biljana; Patterson, Ilse; Lee, Louise; Pollok, Richard; Patel, Jaymin; Seward, Abigail; Baillie, Samantha; Chowdary, Kashfia; Philpott, Sue; Wadke, Anvi; Halligan, Steve; Taylor, Stuart A. 分享 收藏
Safety and efficacy of microwave ablation of lung tumours close to the heart and aorta 微波消融靠近心脏和大动脉的肺肿瘤的安全性和有效性 Li, Y. -L.; Tan, Y.; Mitra, M.; Ko, K. L.; Dmytriw, A.; Scott, S.; Shiels, S. A.; Swinson, A.; Lyon, P.; Anderson, E. M. 分享 收藏
Spatial transcriptomics reveals a key role of fibroblast-like vascular smooth muscle cells in human atherosclerotic cell crosstalk and stability 空间转录组学揭示成纤维样血管平滑肌细胞在人类动脉粥样硬化细胞串扰和稳定性中的关键作用 Goncalves, Isabel; Pan, Mengyu; Singh, Pratibha; Wang, Wenqi; Zhao, Jing; Dib, Lea; Sundius, Lena; Persson, Ana; Gialeli, Chrysostomi; Fountas, Panagiotis; Nitulescu, Mihaela; Nilsson, Jan; Malin, Stephen; Monaco, Claudia; Jorgensen, Helle F.; Sun, Jiangming; Edsfeldt, Andreas 分享 收藏
Improvement in quality of life in inflammatory bowel disease patients treated with advanced therapies: Interim findings from IBD-RESPONSE 使用先进疗法治疗的炎症性肠病患者生活质量改善:IBD-RESPONSE研究的阶段性结果 Watson, H.; Beck, L.; Young, G.; Wyatt, N.; Ahmad, T.; Allerton, D.; Bates, G.; Buckley, A.; Collins, S.; Dong, C.; Doona, M.; Doyle, J.; Fachal, L.; Harris, B.; Hart, A.; Hildreth, V; Irving, P. M.; Jacques, K.; Jostins-Dean, L.; Kennedy, N. A.; Khan, U.; Lees, R.; Liddle, T.; Lees, C.; Lindsay, J.; Marchesi, J.; Martin, C. C.; Mcgregor, N.; Mulligan, R.; Parkes, M.; Prescott, N.; Powell, N.; Raine, T.; Satsangi, J.; Speight, A.; Stewart, C.; Strickland, M.; Wood, R.; Lamb, C. A. 分享 收藏
Longitudinal multi-omic profiling of peripheral blood in acute severe ulcerative colitis reveals a myeloid-driven, steroid-resistant, upadacitinib-sensitive cellular phenotype 急性重症溃疡性结肠炎外周血纵向多组学分析揭示髓系细胞驱动的、类固醇耐药的、乌帕替尼敏感的细胞表型 Pakpoor, J.; Dooley, K.; Agarwal, D.; Pledger, S.; Fergusson, J.; Cripps, S.; Coles, M.; Satsangi, J.; Klenerman, P.; Powrie, F.; Uhlig, H.; Walsh, A.; Brain, O.; Friedrich, M.; Dendrou, C.; Travis, S.; Buckley, C. 分享 收藏
Factors associated with hospitalisations, emergency visits and related costs in inflammatory bowel disease: insights from the TrueColours-IBD digital monitoring programme in Oxford 炎症性肠病患者住院、急诊就诊及其相关费用的相关因素:来自牛津TrueColours-IBD数字监测项目的见解 Fierens, L.; Clarke, P.; Dunbar, G.; Kormilitzin, A.; Matini, L.; Punj Sharda, A.; Travis, S.; Walsh, A.; Violato, M. 分享 收藏
Mirikizumab induction response is associated with molecular and cellular-based tissue archetype features of mucosal recovery in ulcerative colitis 米里克珠单抗诱导反应与溃疡性结肠炎黏膜恢复的分子和细胞基础的组织原型特征相关 Fernandes, N.; Sharma, O.; Ma, C.; Yarur, A.; Deepak, P.; Jain, D.; Pellanda, P.; Maier, S.; Uhlig, H.; Reinisch, W.; Dendrou, C.; Friedrich, M.; Steere, B. 分享 收藏
Clinical, demographic and technical drivers of the IBD microbiome: an interim baseline analysis of the IBD-RESPONSE study 炎症性肠病(IBD)微生物组临床、人口和技术的驱动因素:IBD-RESPONSE研究的初步基线分析 Khan, U.; Young, G.; Beck, L.; Wyatt, N.; Ahmad, T.; Allerton, D.; Bates, G.; Buckley, A.; Collins, S.; Doyle, J.; Fachal, L.; Frith, K.; Gibson, R.; Harris, B.; Hart, A.; Hildreth, V; Irving, P. M.; Kennedy, N. A.; Lawrence, S.; Lees, C.; Lindsay, J.; Marchesi, J.; Martin, C. C.; McGregor, N.; Prescott, N.; Powell, N.; Raine, T.; Speight, A.; Strickland, M.; Watson, H.; Whelan, K.; Wood, R.; Xu, Y.; Parkes, M.; Johnson, J.; Anderson, C.; Stewart, C. J.; Lamb, C. A.; Jostins-Dean, L.; IBD Response Researchers 分享 收藏
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Spatial fibroblast niches shaping Crohn's fistula pathogenesis 空间成纤维细胞微环境在克罗恩病瘘管发生机制中的作用 McGregor, C.; Qin, X.; Jagielowicz, M.; Gupta, T.; Yin, Z.; Lentsch, V; Fawkner-Corbett, D.; Lai, V; Castro, P. Gomez; Bridges, E.; Lee, C. H.; Chuang, H. W.; Deng, L.; Aulicino, A.; Teague, R.; Moradi, S.; Park, J. S.; Woo, J.; Xu, K.; Tandon, R.; Cianci, N.; Bornschein, J.; Ho, L. P.; Siejka-Zielinska, P.; Christoforidou, Z.; Hill, S.; Lehmann, J.; Kujawa, R.; Vargas Gutierrez, P.; Cheng, C.; Greco, M.; Baker, K.; Bignell, M.; George, B.; Fryer, E.; Vieth, M.; Antanaviciute, A.; Simmons, A. 分享 收藏
Fibroblast-Neuron interactions Driving persistent Pain in Rheumatoid Arthritis (FiND-Pain RA) - an observational study protocol 成纤维细胞-神经元相互作用驱动类风湿关节炎持续性疼痛(FiND-Pain RA)——一项观察性研究方案 Xenophontos, Mikalena; Baldeweg, Friederike C.; Ross, Rosie; Rutter-Locher, Zoe; Hill, Sarah; Ryan, Sarah; Ali Awadelkareem, Mosab; Law, Shing T.; Bennett, David L.; Buckley, Christopher D.; Humby, Frances; Kirkham, Bruce W.; Denk, Franziska; Taams, Leonie S. 分享 收藏