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收藏分享 收藏 Assessing the impact and risk of immunomodulatory compounds on pregnancy评估免疫调节化合物对妊娠的影响和风险
Kwak-Kim, Joanne; Maier, Curtis C.; Villano, Caren M.; Bowman, Christopher J.; Brennan, Frank R.; Stanislaus, Dinesh; Hillegas, Aimee; Krayer, John; Prell, Rodney A.; Papenfuss, Tracey L.; Cauvin, Annick; Gamse, Joshua; Dahlman, Anna; Enright, Brian; Leshin, Lawrence; Rao, Gautham K.; Helms, Whitney; Fuller, Claudette L.; Yang, Xiuhua; Chen, Connie; Mitchell-Ryan, Shermaine 分享 收藏 Efficacy, safety, and tolerability of JNJ-61393215 (tebideutorexant), a selective orexin-1 receptor antagonist, as adjunctive treatment for major depressive disorder with anxious distress: A double-blind, placebo-controlled, randomized phase 2a studyJNJ-61393215（tebideutorexant）作为选择性食欲素-1受体拮抗剂，在伴有焦虑困扰的重度抑郁症中的疗效、安全性与耐受性：一项双盲、安慰剂对照、随机2a期研究Schmidt, Mark E.; Moyer, John A.; Kezic, Iva; Zhou, Xianhuang; Samtani, Mahesh N.; Bleys, Cathy; Dallas, Shannon; Salvadore, Giacomo; Drevets, Wayne C. 分享 收藏 Pharmacokinetics, Pharmacodynamics, and Safety of Nipocalimab in Healthy Chinese Volunteers: A Single-Dose, Phase I StudyNipocalimab的药代动力学、药效动力学及安全性研究：一项在中国健康志愿者中进行的单剂量、I期研究Li, Haiyan; Liu, Juanfang; Wang, Xiaohong; Zhao, Weilong; Zhang, Lili; Niu, Xiaoye; Liu, Jingyao; Dong, Zhongqi 分享 收藏 Reductive C(sp2)-C(sp3) Coupling Protocol to Enable Linker Exploration of Cereblon E3-Ligase BRD4 Proteolysis-Targeting Chimeras还原性C(sp2)-C(sp3)偶联方法，用于促进cereblon E3连接酶BRD4蛋白水解靶向嵌合体的连接子探索Lovato, Kaitlyn; Loskot, Danielle; Gelin, Christine; Zhu, Lu; Chaudhry, Charu; Vellore, Nadeem A.; Del Rosario, Amanda; Courtney, Taylor; Miller, Seth; Cho, Ji-Hoon; Bell-Temin, Harris; Venable, Jennifer D.; Brazeau, Jean-Francois 分享 收藏 Real-world analysis of treatment patterns, effectiveness, and safety of daratumumab-based regimens in Chinese patients with newly diagnosed or relapsed/refractory multiple myeloma中国新诊断或复发/难治性多发性骨髓瘤患者中达雷木单抗为基础方案的治疗模式、有效性和安全性的真实世界分析Wang, Luqun; Yang, Wei; Wang, Yafei; Niu, Ting; Fu, Rong; Zhong, Yuping; Qian, Wenbin; Ding, Kaiyang; Sun, Kai; Liu, Hong; Fang, Baijun; Liu, Hui; Li, Yanhui; Yang, Yishen; Zhuo, Jianmin; Chen, Xi; Cui, Canchan; Lu, Jin 分享 收藏 One-Year Efficacy of Guselkumab Versus Advanced Therapies for the Treatment of Moderately to Severely Active Crohn's Disease: A Network Meta-Analysisguselkumab与先进疗法治疗中度至重度活动性克罗恩病的一年疗效：一项网络Meta分析Disher, T; Naessens, D; Sanon, M; Bonner, A; Ellis, J; Bartlett, M; Hooper, B; Yang, ZJ; Allegretti, JR; Dignass, A 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Real-world frontline treatments in patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor exon 20 insertions and adjusted comparisons versus amivantamab plus chemotherapy from the PAPILLON study真实世界中，携带表皮生长因子受体外显子20插入突变的晚期非小细胞肺癌患者的前线治疗方案，以及PAPILLON研究中与阿曼曲单抗联合化疗的调整后比较。Chouaid, Christos; Bosquet, Lise; Knott, Craig; Li, Ziming; Schaeffer, Marcy; Lin, Xiwu; Schioppa, Claudio A.; Perualila, Nolen Joy; Diels, Joris; Caparros, Eduardo Quintero; Galea, Francesca; Hulten, Annika; Greystoke, Alastair 分享 收藏 Real-world data on the use of subcutaneous daratumumab plus bortezomib, thalidomide, and dexamethasone in transplant-eligible patients with newly diagnosed multiple myeloma新诊断多发性骨髓瘤移植适合患者中，皮下注射达雷木单抗联合硼替佐米、沙利度胺和地塞米松用药的真实世界数据Hungria, Vania; Moura, Fernanda Lemos; Costa, Abel; Ribeiro, Eduardo Flavio Oliveira; Soares, Paulo; Lima, Juliana Souza; Ricci, Lisa Aquaroni; Arrais-Rodrigues, Celso; Nucci, Fabio Moore; de Moraes Lima, Marinus; de Magalhaes Filho, Roberto Jose Pessoa; Bhaumik, Amitabha; Parekh, Trilok; Borgsten, Fredrik; Carson, Robin; Trufelli, Damila C.; de Queiroz Crusoe, Edvan 分享 收藏 分享 收藏 Physiologically Based Pharmacokinetic Modeling of Biologic Case Studies in Monkeys and Humans Reveals the Necessity of an Additional Clearance Term基于生理学的药代动力学模型对猴和人类生物制剂案例研究揭示需要增加一个清除项Stader, Felix; Sharma, Pradeep; Huang, Weize; Choules, Mary P.; Willemin, Marie-Emilie; Zhang, Xinwen; Yau, Estelle; Derbalah, Abdallah; Zyla, Adriana; Liu, Cong; Sepp, Armin 分享 收藏 分享 收藏 Stereotactic body radiation therapy and thermal ablation for treatment of patients with pulmonary metastases: a systematic literature review and meta-analysis立体定向体部放射治疗和热消融治疗肺转移患者：一项系统文献综述和荟萃分析Laeseke, Paul; Ng, Calvin; Ferko, Nicole; Naghi, Andrada; Wright, George W. J.; Wang, Di; Laidlaw, Alyshia; Kalsekar, Iftekhar; Amos, Tony; Laxmanan, Balaji; Ghosh, Sudip K.; Zhou, Meijia; Szapary, Philippe; Pritchett, Michael 分享 收藏 分享 收藏 分享 收藏 
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