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张正东 封面图

张正东 (Zhengdong Zhang)

zhejiang chinese medical university

54H指数
410论文数
1.7W被引数
收录论文 160
发表时间
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Identification of Cellular Senescence-Related Hub Genes in Rheumatoid Arthritis from Bioinformatics Analysis Through Machine Learning up to Verifications in Mouse Macrophages and Tests in Patients通过生物信息学分析结合机器学习鉴定类风湿关节炎中细胞衰老相关枢纽基因，并通过小鼠巨噬细胞验证和患者测试进行验证
errInternational Journal of Molecular Sciences
IF4.9
err2026-08-27
err0
errOAAI
errDandan Wang; Linkun Tian; Qingshan Ma; Zhengdong Zhang; Yi Wang; Junhao Fang; Hairong Xu; Qi Chen; Hongdian Chen; Fangyuan Wang; Qiaoyan Zhang; Quanlong Zhang; Luping Qin
err分享
err收藏
Niacin Supplementation Alleviates TCIPP-Induced Lung Injury via Inhibition of the NF-κB Signaling Pathway烟酸补充剂通过抑制NF-κB信号通路缓解TCIPP诱导的肺损伤
errAntioxidants
IF6.6
err2026-03-04
err0
errOAAI
errMeiyu Zhou; Xiaoyu Gao; Ruiyang Tian; Taiyu Gu; Ziwei Dong; Wenjun Shi; Tianyao Mao; Zhengdong Zhang; Haiyan Chu
err分享
err收藏
Extracellular Vesicle-Packaged MIR4435-2HG Facilitates Cigarette Smoke-Induced Bladder Cancer Progression through Enolase 1-Dependent Glycolytic Reprogramming
errACS NANO
IF16
err2025-12-01
err1
PREAI
errZheng, Rui; Xiao, Yanping; Yang, Jialei; Mao, Zhenguang; Tan, Zhiwei; Wei, Chengcheng; Gao, Fang; Wu, Jiajin; Shen, Yang; Huang, Zhengkai; Wang, Meilin; Du, Mulong; Zhang, Zhengdong
err分享
err收藏
Evidence for improved DNA repair in long-lived bowhead whale长寿命弓头鲸DNA修复能力改善的证据
errNature
IF48.5
err2025-10-29
err0
errOAAI
errDenis Firsanov; Max Zacher; Xiao Tian; Todd L. Sformo; Yang Zhao; Gregory Tombline; J. Yuyang Lu; Zhizhong Zheng; Luigi Perelli; Enrico Gurreri; Li Zhang; Jing Guo; Anatoly Korotkov; Valentin Volobaev; Seyed Ali Biashad; Zhihui Zhang; Johanna Heid; Alexander Y. Maslov; Shixiang Sun; Zhuoer Wu; Jonathan Gigas; Eric C. Hillpot; John C. Martinez; Minseon Lee; Alyssa Williams; Abbey Gilman; Nicholas Hamilton; Ekaterina Strelkova; Ena Haseljic; Avnee Patel; Maggie E. Straight; Nalani Miller; Julia Ablaeva; Lok Ming Tam; Chloé Couderc; Michael R. Hoopmann; Robert L. Moritz; Shingo Fujii; Amandine Pelletier; Dan J. Hayman; Hongrui Liu; Yuxuan Cai; Anthony K. L. Leung; Zhengdong Zhang; C. Bradley Nelson; Lisa M. Abegglen; Joshua D. Schiffman; Vadim N. Gladyshev; Carlo C. Maley; Mauro Modesti; Giannicola Genovese; Mirre J. P. Simons; Jan Vijg; Andrei Seluanov; Vera Gorbunova
err分享
err收藏
TRAF6 Exerts Tumor-Promoting Effects via Genetic and Autophagic Modulation in Gastric CancerTRAF6通过遗传和自噬调控在胃癌中发挥促肿瘤作用
errMolecular Carcinogenesis
IF3.2
err2025-08-19
err0
PREAI
errYifan Zou; Zhenguang Mao; Jianghao Xu; Weizhi Wang; Zhihao Wang; Jianghong Dai; Rui Zheng; Mulong Du; Zhengdong Zhang
err分享
err收藏
Addressing osteoblast senescence: Molecular pathways and the frontier of anti-ageing treatments解决成骨细胞衰老：分子通路与抗衰老治疗的 Frontier
errClinical and Translational Medicine
IF6.8
err2025-07-18
err0
errOAAI
errZhengdong Zhang; Pan Liu; Yu Song; Liang Ma; Yan Xu; Jie Lei; Bide Tong; Dingchao Zhu; Huaizhen Liang; Hongchuan Wang; Xingyu Zhou; Zixuan Ou; Junyu Wei
err分享
err收藏
An integrative multi-omics study to identify candidate DNA methylation biomarkers associated with gastric cancer prognosis一项整合多组学研究，以识别与胃癌预后相关的候选DNA甲基化生物标志物
errArchives of Toxicology
IF6.9
err2025-07-05
err0
PREAI
errJingjing Gu; Yanling Wu; Wenyue Tao; Junyi Xin; Hanting Liu; Weida Gong; Qinghong Zhao; Haiyan Chu; Mulong Du; Meilin Wang; Dongmei Wu; Guoquan Tao; Zhengdong Zhang
err分享
err收藏
Tobacco smoking exposure-mediated ELAVL1 regulates bladder cancer cell senescence via autophagy activation烟草烟雾暴露介导的ELAVL1通过自噬激活调节膀胱癌细胞衰老
errToxicology
IF4.6
err2025-06-05
err0
PREAI
errQiuyi Pu; Fang Gao; Yanping Xiao; Jiajin Wu; Chao Wang; Xiaoxiao Mo; Zhengdong Zhang; Rui Zheng; Dongmei Wu
err分享
err收藏
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer ( Apr, 10.1038/s43587-025-00842-0, 2025)单细胞和空间RNA测序识别早期与晚期前列腺癌中不同的微环境和进展特征 (Apr, 10.1038/s43587-025-00842-0, 2025)
errNATURE AGING
IF19.4
err2025-05-12
err0
PREAI
errCheng, Yifei; Liu, Bingxin; Xin, Junyi; Wu, Xiaobin; Li, Wenchao; Shang, Jinwei; Wu, Jiajin; Zhang, Zhengdong; Xu, Bin; Du, Mulong; Cheng, Gong; Wang, Meilin
err分享
err收藏
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer单细胞及空间RNA测序识别早期与晚期前列腺癌中不同的微环境和进展特征
errNATURE AGING
IF19.4
err2025-04-10
err0
PREAI
errCheng, Yifei; Liu, Bingxin; Xin, Junyi; Wu, Xiaobin; Li, Wenchao; Shang, Jinwei; Wu, Jiajin; Zhang, Zhengdong; Cheng, Gong
err分享
err收藏
Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity经微针递送CAR-M样工程巨噬细胞可通过增强清理性吞噬能力缓解椎间盘退变
errCELL REPORTS MEDICINE
IF10.6
err2025-04-01
err0
errOAAI
errZhou, Xingyu; Zhu, Dingchao; Wu, Di; Li, Gaocai; Liang, Huaizhen; Zhang, Weifeng; Wu, Yali; Xu, Hanpeng; Zhang, Zhengdong; Tong, Bide; Song, Yu; Wang, Kun; Feng, Xiaobo; Lei, Jie; Wang, Hongchuan; Zhang, Xiaoguang; Ma, Liang; Chen, Yuhang; Wei, Junyu; Ou, Zixuan; Peng, Shuchang; Wu, Xinghuo; Tan, Lei; Wang, Bingjin; Yang, Cao
err分享
err收藏
Genetic variants reduced POPs-related colorectal cancer risk via altering miRNA binding affinity and m6A modification
errENVIRONMENT INTERNATIONAL
IF9.7
err2024-08-01
err0
errOAAI
errGuo, Mengfan; Li, Shuwei; Cheng, Yifei; Xin, Junyi; Zhou, Jieyu; Xu, Shenya; Ben, Shuai; Wang, Meilin; Zhang, Zhengdong; Gu, Dongying
err分享
err收藏
Colonization of bacterial and viral respiratory pathogens among healthcare workers in China during COVID-19 pandemic
errJOURNAL OF ORAL MICROBIOLOGY
IF5.5
err2024-06-20
err1
errOAAI
errYang, Dandan; Xu, Jianan; Wu, Tao; Zhang, Wei; Zhu, Xiaojun; Zhang, Zhengdong; Zhu, Baoli
err分享
err收藏
Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers独特的多细胞免疫抑制中心为左侧和右侧结肠癌提供了不同的干预策略
errCELL REPORTS MEDICINE
IF10.6
err2024-06-01
err2
errOAAI
errLiu, Bingxin; Li, Shuwei; Cheng, Yifei; Song, Peng; Xu, Menghuan; Li, Zhengyi; Shao, Wei; Xin, Junyi; Fu, Zan; Gu, Dongying; Du, Mulong; Zhang, Zhengdong; Wang, Meilin
err分享
err收藏
Single-cell and multi-omics analyses highlight cancer-associated fibroblasts-induced immune evasion and epithelial mesenchymal transition for smoking bladder cancer
errTOXICOLOGY
IF4.6
err2024-05-01
err1
PREAI
errWu, Jiajin; Gao, Fang; Meng, Rui; Li, Huiqin; Mao, Zhenguang; Xiao, Yanping; Pu, Qiuyi; Du, Mulong; Zhang, Zhengdong; Shao, Qiang; Zheng, Rui; Wang, Meilin
err分享
err收藏
AKR1C2 genetic variants mediate tobacco carcinogens metabolism involving bladder cancer susceptibility
errARCHIVES OF TOXICOLOGY
IF6.9
err2024-04-25
err0
PREAI
errXiao, Yanping; Shen, Yang; Song, Hui; Gao, Fang; Mao, Zhenguang; Lv, Qiang; Qin, Chao; Yuan, Lin; Wu, Dongmei; Chu, Haiyan; Wang, Meilin; Du, Mulong; Zheng, Rui; Zhang, Zhengdong
err分享
err收藏
Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment
errNATURE COMMUNICATIONS
IF15.7
err2024-04-08
err2
errOAAI
errXin, Junyi; Gu, Dongying; Li, Shuwei; Qian, Sangni; Cheng, Yifei; Shao, Wei; Ben, Shuai; Chen, Silu; Zhu, Linjun; Jin, Mingjuan; Chen, Kun; Hu, Zhibin; Zhang, Zhengdong; Du, Mulong; Shen, Hongbing; Wang, Meilin
err分享
err收藏
Choledochoscopic lithotomy for the treatment of massive commonbile-duct stones: A case report and literature review
errASIAN JOURNAL OF SURGERY
IF3.8
err2024-04-01
err0
errOAAI
errFu, Bing; Zhang, Zhengdong; Ji, Hui; Hou, Yafeng
err分享
err收藏
Assessment of human exposure to cadmium and its nephrotoxicity in the Chinese population
errSCIENCE OF THE TOTAL ENVIRONMENT
IF8
err2024-03-01
err20
PREAI
errZhu, Huanhuan; Tang, Xiying; Gu, Chunyan; Chen, Riming; Liu, Yadong; Chu, Haiyan; Zhang, Zhengdong
err分享
err收藏
PM2.5-derived exosomal long noncoding RNA PAET participates in childhood asthma by enhancing DNA damage via m6A-dependent OXPHOS regulation
errENVIRONMENT INTERNATIONAL
IF9.7
err2024-01-01
err5
errOAAI
errZheng, Rui; Gao, Fang; Xiao, Yanping; Liang, Jiayuan; Mao, Zhenguang; Gan, Cong; Song, Hui; Du, Mulong; Wang, Meilin; Tian, Man; Zhang, Zhengdong
err分享
err收藏

研究方向

环境相关重大疾病病因学与发病机制研究主要学术兼职江苏省环境诱变剂学会副理事长江苏省预防医学会常务理事外泌体非编码RNA表观遗传调控机制烟草烟雾源性外泌体蛋白介导巨噬细胞极化诱发儿童哮喘的机制研究高危人群识别技术研发COVID-19的多组学评估环境暴露与哮喘细胞外囊泡信号通路细颗粒物诱导METTL3介导的m6A修饰PM2.5诱导细胞损伤的分子机制lncRNA GCLET在胃癌遗传易感性中的调控机制fine particulate mattergenetic variantscolorectal cancer risk有机磷阻燃剂肺功能损伤IL-6/JAK/STAT信号通路PM2.5来源外泌体长非编码RNA参与儿童哮喘肿瘤遗传学基因组学膀胱癌human exposure to cadmiumnephrotoxicity
合作学者
合作期刊
M
M Snyder
H 指数: 210 · 论文数: 3.3K
M
Mark Gerstein
H 指数: 191 · 论文数: 1.2K
M
Michael J. Owen
H 指数: 164 · 论文数: 1.2K
李金 封面图
李金 (Jin Li)
H 指数: 149 · 论文数: 4.5K
R
Raquel E. Gur
H 指数: 144 · 论文数: 1.2K
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