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D

Darren G. Monckton

University of Manchester

44H指数
188论文数
7.2K被引数
收录论文 75
发表时间
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Genetic testing for Huntington's disease: Past, present and future. How could genetic data be used to improve clinical practice?亨廷顿病的基因检测：过去、现在和未来。基因数据如何用于改进临床实践？
errJournal of Huntingtons Disease
IF3.1
err2025-12-01
err0
PREAI
errMoss, Davina J. Hensman; Ireland, Rhiannon; Chapman, Guy; MacLeod, Rhona; Labrum, Robyn; Polke, James M.; Monckton, Darren G.; Holmans, Peter; Massey, Tom H.; Lahiri, Nayana
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Huntington disease: somatic expansion, pathobiology and therapeutics亨廷顿病：体细胞扩展、病理生物学和治疗学
errNature Reviews Neurology
IF33.1
err2025-11-13
err0
PREAI
errJasmine Donaldson; Davina Hensman Moss; Marc Ciosi; Karen Usdin; Gabriel Balmus; Darren G. Monckton; Sarah J. Tabrizi
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Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease脑脊液前强啡肽预测亨廷顿病临床运动诊断前数十年纹状体萎缩
errMovement Disorders
IF7.6
err2025-09-26
err0
errOAAI
errMena Farag MBBS, MRCP; Michael J. Murphy MB BCh BAO, MRCPI; Nicola Z. Hobbs PhD; Michela Leocadi PhD; Kate Fayer MRes; Olivia Thackeray MSc; Johan Gobom PhD; Marc Ciosi PhD; Amanda Heslegrave PhD; Henrik Zetterberg PhD; Douglas R. Langbehn MD, PhD; Darren G. Monckton PhD; Edward J. Wild MB BChir, FRCP, PhD; Sarah J. Tabrizi MBChB, FRCP, PhD, FMedSci; Rachael I. Scahill PhD
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Genetic and Demographic Determinants of Fuchs Endothelial Corneal Dystrophy Risk and SeverityFuchs内皮角膜营养不良风险和严重程度的遗传与人口学决定因素
errJAMA OPHTHALMOLOGY
IF9.2
err2025-04-01
err0
errOAAI
errLiu, Siyin; Sadan, Amanda N.; Bhattacharyya, Nihar; Zarouchlioti, Christina; Szabo, Anita; Abreu Costa, Marcos; Hafford-Tear, Nathaniel J.; Kladny, Anne-Marie S.; Dudakova, Lubica; Ciosi, Marc; Moghul, Ismail; Wilkins, Mark R.; Allan, Bruce; Skalicka, Pavlina; Hardcastle, Alison J.; Pontikos, Nikolas; Bunce, Catey; Monckton, Darren G.; Muthusamy, Kirithika; Liskova, Petra; Tuft, Stephen J.; Davidson, Alice E.
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International collaboration to improve knowledge on myotonic dystrophy type 2国际合作以改进对强直性肌营养不良2型的认知
errJOURNAL OF NEUROMUSCULAR DISEASES
IF3.4
err2024-12-08
err0
errOAAI
errPeric, Stojan; Ivanovic, Vukan; Ashley, Emma-Jayne; Esparis, Belen; Campbell, Craig; Wenninger, Stephan; Monckton, Darren; Marini-Bettolo, Chiara; Walker, Helen; Vohanka, Stanislav; Cumming, Kleed; Lusakowska, Anna; Hodgkinson, Victoria; Cosyns, Marjan; Rodrigues, Miriam; Yiu, Eppie; Mazanec, Radim; Stevenson, Tanya; Kostera-Pruszczyk, Anna; Korngut, Lawrence; Jagut, Marlene; Schoser, Benedikt; Forbes, Robin; Poll, Annie; Roxburgh, Richard
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Age-dependent somatic expansion of the ATXN3 CAG repeat in the blood and buccal swab DNA of individuals with spinocerebellar ataxia type 3/Machado-Joseph disease
errHUMAN GENETICS
IF3.6
err2024-10-08
err1
errOAAI
errSidky, Ahmed M.; Melo, Ana Rosa Vieira; Kay, Teresa T.; Raposo, Mafalda; Lima, Manuela; Monckton, Darren G.
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Ameliorated cellular hallmarks of myotonic dystrophy in hybrid myotubes from patient and unaffected donor cells
errSTEM CELL RESEARCH & THERAPY
IF7.3
err2024-09-15
err0
errOAAI
errRaaijmakers, Renee H. L.; Ausems, C. Rosanne M.; Willemse, Marieke; Cumming, Sarah A.; van Engelen, Baziel G. M.; Monckton, Darren G.; van Bokhoven, Hans; Wansink, Derick G.
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Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onsetdelaying genetic modification in Huntington's disease
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-04-12
err1
errOAAI
errKim, Kyung-Hee; Hong, Eun Pyo; Lee, Yukyeong; Mclean, Zachariah L.; Elezi, Emanuela; Lee, Ramee; Kwak, Seung; Mcallister, Branduff; Massey, Thomas H.; Lobanov, Sergey; Holmans, Peter; Orth, Michael; Ciosi, Marc; Monckton, Darren G.; Long, Jeffrey D.; Lucente, Diane; Wheeler, Vanessa C.; Macdonald, Marcy E.; Gusella, James F.; Lee, Jong- Min
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Phenome-wide analysis reveals epistatic associations between APOL1 variants and chronic kidney disease and multiple other disorders
errEBIOMEDICINE
IF10.8
err2024-03-01
err0
errOAAI
errAdamson, Walt E.; Noyes, Harry; Johnson, Paul; Cooper, Anneli; Monckton, Darren G.; Ogunsola, John; Beckett-Hill, Georgia; Sullivan, Michael; Mark, Patrick; Parekh, Rulan S.; MacLeod, Annette
err分享
err收藏
Modification of Huntington's disease by short tandem repeats
errBRAIN COMMUNICATIONS
IF4.5
err2024-01-23
err2
errOAAI
errHong, Eun Pyo; Ramos, Eliana Marisa; Aziz, N. Ahmad; Massey, Thomas H.; Mcallister, Branduff; Lobanov, Sergey; Jones, Lesley; Holmans, Peter; Kwak, Seung; Orth, Michael; Ciosi, Marc; Lomeikaite, Vilija; Monckton, Darren G.; Long, Jeffrey D.; Lucente, Diane; Wheeler, Vanessa C.; Gillis, Tammy; Macdonald, Marcy E.; Sequeiros, Jorge; Gusella, James F.; Lee, Jong-Min
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Repeat Detector: versatile sizing of expanded tandem repeats and identification of interrupted alleles from targeted DNA sequencing
errgenomics proteomics bioinformatics
IF2.8
err2022-12-05
err6
errOAAI
errTaylor, Alysha S.; Barros, Dinis; Gobet, Nastassia; Schuepbach, Thierry; McAllister, Branduff; Aeschbach, Lorene; Randall, Emma L.; Trofimenko, Evgeniya; Heuchan, Eleanor R.; Barszcz, Paula; Ciosi, Marc; Morgan, Joanne; Hafford-Tear, Nathaniel J.; Davidson, Alice E.; Massey, Thomas H.; Monckton, Darren G.; Jones, Lesley; Xenarios, Ioannis; Dion, Vincent
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A probable cis-acting genetic modifier of Huntington disease frequent in individuals with African ancestry
errHUMAN GENETICS AND GENOMICS ADVANCES
IF3.6
err2022-10-01
err10
errOAAI
errDawson, Jessica; Baine-Savanhu, Fiona K.; Ciosi, Marc; Maxwell, Alastair; Monckton, Darren G.; Krause, Amanda
err分享
err收藏
LONGITUDINAL ANALYSIS OF SOMATIC EXPANSION OF THE HTT REPEAT IN BLOOD AS A POTENTIAL BIOMARKER OF SOMATIC INSTABILITY IN HUNTINGON DISEASE
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2022-09-12
err0
PREAI
errCiosi, Marc; Young, Robin; Kwak, Seung; Monckton, Darren G.
err分享
err收藏
SOMATIC MOSAICISM OF THE HTT CAG REPEAT IN INTERMEDIATE ALLELE CARRIERS WITH NEUROCOGNITIVE SYMPTOMS COMPATIBLE WITH HUNTINGTON DISEASE
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2022-09-12
err0
PREAI
errRuiz de Sabando, Ainara; Ciosi, Marc; Galbete, Arkaitz; Monckton, Darren G.; Ramos-Arroya, Maria R.
err分享
err收藏
MSH3-TARGETING ANTISENSE OLIGONUCLEOTIDES HALT CAG REPEAT EXPANSIONS IN HUNTINGTON'S DISEASE IPSC-DERIVED NEURONS
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2022-09-12
err1
PREAI
errBunting, Emma; Donaldson, Jasmine; Olive, Jessica; Kordasiewicz, Holly; Bennett, Frank; Cumming, Sarah A.; Monckton, Darren G.; Flower, Michael; Tabrizi, Sarah J.
err分享
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THE HD YOUNG ADULT STUDY 2: LONGITUDINAL FOLLOW UP
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2022-09-12
err0
PREAI
errScahill, Rachael I.; Sahakian, Barbara J.; Robbins, Trevor W.; Zhang, Hui; Rees, Geraint; Langbehn, Douglas; Rowe, James B.; Monckton, Darren G.; Tabrizi, Sarah J.
err分享
err收藏
Genetic modifiers of Huntington disease differentially influence motor and cognitive domains亨廷顿病的遗传修饰因子对运动和认知域的影响不同
errAMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
err2022-05-01
err31
errOAAI
errLee, Jong-Min; Huang, Yuan; Orth, Michael; Gillis, Tammy; Siciliano, Jacqueline; Hong, Eunpyo; Mysore, Jayalakshmi Srinidhi; Lucente, Diane; Wheeler, Vanessa C.; Seong, Ihn Sik; McLean, Zachariah L.; Mills, James A.; McAllister, Branduff; Lobanov, Sergey, V; Massey, Thomas H.; Ciosi, Marc; Landwehrmeyer, G. Bernhard; Paulsen, Jane S.; Dorsey, E. Ray; Shoulson, Ira; Sampaio, Cristina; Monckton, Darren G.; Kwak, Seung; Holmans, Peter; Jones, Lesley; MacDonald, Marcy E.; Long, Jeffrey D.; Gusella, James F.
err分享
err收藏
Myotonic dystrophy type 1 (DM1) clinical subtypes and CTCF site methylation status flanking the CTG expansion are mutant allele length-dependent
errHUMAN MOLECULAR GENETICS
IF3.2
err2021-08-25
err13
errOAAI
errMorales, Fernando; Corrales, Eyleen; Zhang, Baili; Vasquez, Melissa; Santamaria-Ulloa, Carolina; Quesada, Hazel; Sirito, Mario; Estecio, Marcos R.; Monckton, Darren G.; Krahe, Ralf
err分享
err收藏
Neurocognitive Features of Motor Premanifest Individuals With Myotonic Dystrophy Type 1
errNEUROLOGY-GENETICS
IF3.7
err2021-04-01
err5
errOAAI
errvan der Plas, Ellen; Koscik, Timothy R.; Magnotta, Vincent; Cumming, Sarah A.; Monckton, Darren; Gutmann, Laurie; Nopoulos, Peggy
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err收藏
Associations Between Variant Repeat Interruptions and Clinical Outcomes in Myotonic Dystrophy Type 1
errNEUROLOGY-GENETICS
IF3.7
err2021-04-01
err11
errOAAI
errWenninger, Stephan; Cumming, Sarah A.; Gutschmidt, Kristina; Okkersen, Kees; Jimenez-Moreno, Aura Cecilia; Daidj, Ferroudja; Lochmuller, Hanns; Hogarth, Fiona; Knoop, Hans; Bassez, Guillaume; Monckton, Darren G.; van Engelen, Baziel G. M.; Schoser, Benedikt
err分享
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