Coert J. Zuurbier - Publications, H-index & Citations

Coert J. Zuurbier

department of anesthesiology

50H指数

183论文数

7.7K被引数

收录论文 89

发表时间

NLRX1 emerges as the only observed essential regulator of the mPTP, challenging mPTP inhibition as a valid target of cardioprotection NLRX1作为唯一观察到的mPTP必需调节因子出现，挑战了mPTP抑制作为心脏保护有效靶点的观点

Basic Research in Cardiology

IF8

2026-08-19

OAAI

Kielen R. Zuurbier; Coert J. Zuurbier

Metabolic dependency of malonate protection against cardiac ischemia–reperfusion injury 丙二酸保护心脏缺血-再灌注损伤的代谢依赖性

Basic Research in Cardiology

IF8

2026-08-17

OAAI

Qian Wang; Xin Hu; Yang Xiao; Rianne Nederlof; Panagiota-Efstathia Nikolaou; Christina Chania; Diane Bakker; Amrita Kim Singh; Markus W. Hollmann; Nina C. Weber; Bauke Schomakers; Michel van Weeghel; Coert J. Zuurbier

Unravelling mitochondrial succinate transport during I/R and devising a novel transport inhibitor show promise for targeting I/R injury, but will efficacy remain under more human-like conditions present during I/R?阐明缺血再灌注（I/R）期间线粒体琥珀酸盐转运并设计新型转运抑制剂为靶向I/R损伤提供了前景，但在I/R期间更接近人体实际条件的条件下，其疗效能否保持？

Cardiovascular Research

IF13.3

2026-04-01

PREAI

Wang, Qian; Hu, Xin; Zuurbier, Coert J.

The early metabolic cardiac targets of empagliflozin during the development of heart failure, independent of SGLT2 inhibition 恩格列净在心力衰竭发展过程中早期的心脏代谢靶点，独立于SGLT2抑制

Metabolism

IF3.7

2026-02-16

OAAI

Sha Chen; Xin Hu; Qian Wang; Diane Bakker; Inge van der Made; Anna M. Tebbens; Yingyin Guan; Myrto Lykidou; Femke K.J. van Goor; Markus W. Hollmann; Nina C. Weber; Michel van Weeghel; Bauke V. Schomakers; Michael P. Pieper; Ruben Coronel; Esther E. Creemers; Coert J. Zuurbier

Sodium-myo-inositol cotransporter-1, SMIT1, promotes cardiac hypertrophy and fibrosis induced by pressure overload in mice Sodium myo-inositol cotransporter-1, SMIT1，在压力超负荷小鼠心脏中促进心肌肥厚和纤维化。

Cardiovascular Research

IF13.3

2026-02-01

PREAI

Marino, Alice; Cumps, Julien; Guilbert, Laura; Geiser, Angeline; Baufays, Claire; Ginion, Audrey; Ferte, Laura; Battault, Sylvain; De Matos, Fiona; Ambroise, Jerome; Zuurbier, Coert J.; Lezoualc'h, Frank; Pestiaux, Camille; Pyka, Grzegorz; Kerckhofs, Greet; Roderick, H. Llewelyn; Bertrand, Luc; Horman, Sandrine; Beauloye, Christophe

Correction: IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT): a small animal acute myocardial infarction randomized-controlled multicenter study on the effect of ischemic preconditioning 更正：改善心血管保护疗法预临床评估（IMPACT）：一项关于缺血预处理对急性心肌梗死影响的小动物随机对照多中心研究

Basic Research in Cardiology

IF8

2025-11-10

OAAI

Sauri Hernandez-Resendiz; Reinis Vilskersts; David Aluja; Ioanna Andreadou; Péter Bencsik; Maija Dambrova; Panagiotis Efentakis; Fei Gao; Zoltán Giricz; Gábor B. Brenner; Nabil V. Sayour; Tamás G. Gergely; András Makkos; Javier Inserte; Roisin Kelly-Laubscher; Attila Kiss; Thomas Krieg; Brenda R. Kwak; Sandrine Lecour; Gary Lopaschuk; Michał Mączewski; Michał Waszkiewicz; Marta Oknińska; Pasquale Pagliaro; Bruno Podesser; Hiran A. Prag; Marisol Ruiz-Meana; Tamara Szabados; Coert J. Zuurbier; Péter Ferdinandy; Derek J. Hausenloy

Cardiac intermediary metabolism in heart failure: substrate use, signalling roles and therapeutic targets 心力衰竭中的心脏中间代谢: 底物使用，信号作用和治疗靶标

Nature Reviews Cardiology

IF44.2

2025-06-22

PREAI

Mathias Mericskay; Coert J. Zuurbier; Lisa C. Heather; Anja Karlstaedt; Javier Inserte; Luc Bertrand; Georgios Kararigas; Marisol Ruiz-Meana; Christoph Maack; Gabriele G. Schiattarella

The innate immune receptor NLRX1 is a novel required modulator for mPTP opening: implications for cardioprotection 先天免疫受体NLRX1是mPTP开放的必要新型调节因子：对心脏保护的意义

Basic Research in Cardiology

IF8

2025-06-19

OAAI

Y. Xiao; X. Hu; C. F. Rudolphi; E. E. Nollet; R. Nederlof; Q. Wang; D. Bakker; Panagiota Efstathia Nikolaou; J. C. Knol; R. R. Goeij-de Haas; A. A. Henneman; T. V. Pham; C. R. Jimenez; A. E. Grootemaat; N. N. van der Wel; S. E. Girardin; N. Kaludercic; J. van der Velden; Z. Onódi; P. Leszek; Z. V. Varga; P. Ferdinandy; B. Preckel; N. C. Weber; M. W. Hollmann; F. Di Lisa; C. J. Zuurbier

Effects of SGLT2 inhibitors on ion channels in heart failure: focus on the endothelium SGLT2抑制剂对心力衰竭中离子通道的影响：聚焦内皮细胞

BASIC RESEARCH IN CARDIOLOGY

IF8

2025-05-14

OAAI

Mengnan Wang; Benedikt Preckel; Coert J. Zuurbier; Nina C. Weber

Empagliflozin in Acute Myocardial Infarction Reduces No-Reflow and Preserves Cardiac Function by Preventing Endothelial Damage 依格列净在急性心肌梗死中通过预防内皮损伤来减少无复流并保护心脏功能

JACC-BASIC TO TRANSLATIONAL SCIENCE

IF7.2

2025-01-01

OAAI

Nikolaou, Panagiota Efstathia; Konijnenberg, Lara S. F.; V. Kostopoulos, Ioannis; Miliotis, Marios; Mylonas, Nikolaos; Georgoulis, Anastasios; Pavlidis, George; Kuster, Carolien T. A.; Reijmersdal, Vince P. A. van; Luiken, Tom T. J.; Agapaki, Anna; Roverts, Rona; Orologas, Nikolaos; Grigoriadis, Dimitris; Pallot, Gaetan; Boucher, Pierre; Kostomitsopoulos, Nikolaos; Pieper, Michael Paul; Germain, Stephane; Loukas, Yannis; Dotsikas, Yannis; Ikonomidis, Ignatios; Hatzigeorgiou, Artemis G.; Tsitsilonis, Ourania; Zuurbier, Coert J.; Nijveldt, Robin; van Royen, Niels; Andreadou, Ioanna

Empagliflozin prevents TNF-α induced endothelial dysfunction under flow -the potential involvement of calcium and sodium-hydrogen exchanger

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2025-01-01

OAAI

Li, Xiaoling; Wang, Mengnan; Wolfsgruber, Marlene; Klatt, Olivia C.; Hollmann, Markus W.; Preckel, Benedikt; Zuurbier, Coert J.; Weber, Nina C.

Empagliflozin treatment pre- and post- acute myocardial infarction reduces no-reflow, inflammatory cell infiltration and infarct size while preserving cardiac function.

EUROPEAN HEART JOURNAL

IF35.6

2024-10-28

PREAI

Nikolaou, P. E.; Konijnenberg, L.; Kostopoulos, I., V; Milliotis, M.; Mylonas, N.; Georgoulis, A.; Pavlidis, G.; Pieper, M. P.; Ikonomidis, I.; Hatzigeorgiou, A.; Tsitsilonis, O.; Zuurbier, C. J.; Nijveldt, R.; Royen, N., V; Andreadou, I

Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2 Empagliflozin通过抑制NHE1-NO途径预防心力衰竭，独立于SGLT2

BASIC RESEARCH IN CARDIOLOGY

IF8

2024-07-24

OAAI

Chen, Sha; Wang, Qian; Bakker, Diane; Hu, Xin; Zhang, Liping; van der Made, Ingeborg; Tebbens, Anna M.; Kovacshazi, Csenger; Giricz, Zoltan; Brenner, Gabor B.; Ferdinandy, Peter; Schaart, Gert; Gemmink, Anne; Hesselink, Matthijs K. C.; Rivaud, Mathilde R.; Pieper, Michael P.; Hollmann, Markus W.; Weber, Nina C.; Balligand, Jean-Luc; Creemers, Esther E.; Coronel, Ruben; Zuurbier, Coert J.

Empagliflozin mitigates cardiac hypertrophy through cardiac RSK/ NHE-1 inhibition

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2024-05-01

OAAI

Chen, Sha; Overberg, Kenneth; Ghouse, Zakiya; Hollmann, Markus W.; Weber, Nina C.; Coronel, Ruben; Zuurbier, Coert J.

Insulin and glycolysis dependency of cardioprotection by nicotinamide riboside

BASIC RESEARCH IN CARDIOLOGY

IF8

2024-03-25

OAAI

Xiao, Y.; Wang, Q.; Zhang, H.; Nederlof, R.; Bakker, D.; Siadari, B. A.; Wesselink, M. W.; Preckel, B.; Weber, N. C.; Hollmann, M. W.; Schomakers, B. V.; van Weeghel, M.; Zuurbier, C. J.

NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy

CELLS

IF5.2

2023-12-21

OAAI

Liu, Ye; Kors, Lotte; Butter, Loes M.; Stokman, Geurt; Claessen, Nike; Zuurbier, Coert J.; Girardin, Stephen E.; Leemans, Jaklien C.; Florquin, Sandrine; Tammaro, Alessandra

Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells

FRONTIERS IN PHYSIOLOGY

IF3.4

2023-07-26

OAAI

Chen, Sha; Schumacher, Cees A.; Van Amersfoorth, Shirley C. M.; Fiolet, Jan W. T.; Baartscheer, Antonius; Veldkamp, Marieke W.; Coronel, Ruben; Zuurbier, Coert J.

Pharmacological Cardioprotection against Ischemia Reperfusion Injury-The Search for a Clinical Effective Therapy

CELLS

IF5.2

2023-05-20

OAAI

Wang, Qian; Zuurbier, Coert J.; Huhn, Ragnar; Torregroza, Carolin; Hollmann, Markus W.; Preckel, Benedikt; van den Brom, Charissa E.; Weber, Nina C.

Canagliflozin inhibits inflammasome activation in diabetic endothelial cells-Revealing a novel calcium-dependent anti-inflammatory effect of canagliflozin on human diabetic endothelial cells

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2023-03-01

OAAI

Li, Xiaoling; Kerindongo, Raphaela P.; Preckel, Benedikt; Kalina, Jan-Ole; Hollmann, Markus W.; Zuurbier, Coert J.; Weber, Nina C.

Sodium Glucose Cotransporter-2 Inhibitor Empagliflozin Reduces Infarct Size Independently of Sodium Glucose Cotransporter-2 钠葡萄糖Cotransporter-2抑制剂依巴列净独立于钠葡萄糖Cotransporter-2减少梗死面积

CIRCULATION

IF38.6

2023-01-17

PREAI

Chen, Sha; Wang, Qian; Christodoulou, Andriana; Mylonas, Nikolaos; Bakker, Diane; Nederlof, Rianne; Hollmann, Markus W.; Weber, Nina C.; Coronel, Ruben; Wakker, Vincent; Christoffels, Vincent M.; Andreadou, Ioanna; Zuurbier, Coert J.

研究方向