David Dulin - Publications, H-index & Citations

David Dulin

vrije universiteit amsterdam

25H指数

136论文数

2.3K被引数

收录论文 42

发表时间

Integrative structure of norovirus NS3 suggests a role in RNA transport 诺如病毒NS3整合结构提示其在RNA转运中的作用

Nature Communications

IF15.7

2026-09-21

OAAI

Meryl Haas; Tino Hoeksma; Jake T. Mills; Cynthia Kelley; Arnab Das; Kankipati Teja Shyam; Robin Veenstra; Owen Byford; Henrietta Hóf; Coco Niemel; Tim Donselaar; Ieva Drulyte; Frank J. M. van Kuppeveld; David Dulin; Joost Snijder; Morgan R. Herod; Daniel L. Hurdiss

The nucleoside analog CMX521 inhibits coronavirus RNA-dependent RNA polymerase via a two-pronged mechanism 核苷类似物CMX521通过双机制抑制冠状病毒RNA依赖性RNA聚合酶

Journal of Biological Chemistry

IF3.9

2026-09-16

OAAI

Asif Rakib; Calvin J. Gordon; Thomas K. Anderson; John C. Marecki; Quinte Smitskamp; Nathaniel J. Moorman; Mark T. Heise; Heidi M. Colton; Dean Selleseth; Randall Lanier; Kevin D. Raney; Robert N. Kirchdoerfer; Matthias Götte; David Dulin

Copy-back RNA synthesis by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir 冠状病毒聚合酶介导的复制回环RNA合成需要解旋酶活性，并受到瑞德西韦和莫诺拉韦的刺激

Science Advances

IF12.5

2026-06-19

OAAI

Asif Rakib; Arnab Das; Subhas C. Bera; Jelmer Cnossen; Refugio Robles-Sikisaka; Meghan V. Diefenbacher; Pim P. B. America; Misha Klein; Thomas K. Anderson; John C. Marecki; Bing Wang; Eline Bogers; Joy Y. Feng; John P. Bilello; Flávia S. Papini; Quinte Smitskamp; Timothy P. Sheahan; Jamie J. Arnold; Andrew Routh; Irina Artsimovitch; Robert N. Kirchdoerfer; Craig E. Cameron; Kevin D. Raney; David Dulin

RNA virus polymerase-helicase coupling enables rapid elongation through duplex RNA RNA病毒聚合酶-解旋酶偶联通过双链RNA实现快速延伸

Cell Reports

IF6.9

2026-04-16

OAAI

Pim P.B. America; Subhas C. Bera; Arnab Das; Thomas K. Anderson; John C. Marecki; Flávia S. Papini; Jamie J. Arnold; Robert N. Kirchdoerfer; Craig E. Cameron; Kevin D. Raney; Martin Depken; David Dulin

MDA5 generates compact ribonucleoprotein complexes via ATP-dependent double-stranded RNA unwinding MDA5通过ATP依赖的双链RNA解旋生成紧凑的核糖核蛋白复合物

Nucleic Acids Research

IF13.1

2026-04-13

OAAI

Quack, Salina; Maity, Sourav; America, Pim P. B.; Klein, Misha; del Valle, Alba Herrero; Singh, Rahul; Joiner, Joe D.; Rashid, Zainab M.; Smitskamp, Quinte; Rivas, Paula; Papini, Flavia s; Broedersz, Chase P.; Roos, Wouter H.; Modis, Yorgo; Dulin, David

TAV2b Peptide Derivatives Underwind and Stabilize Double-Stranded RNA upon Binding TAV2b肽衍生物在结合时使双链RNA松旋并稳定化

Journal of the American Chemical Society

IF15.6

2026-02-20

OAAI

Zainab M. Rashid; Misha Klein; Thor van Heesch; Salina Quack; Quinte Smitskamp; Pim P. B. America; Paula Rivas; Marvin A. Albers; Jannik Paulus; Jocelyne Vreede; Tom N. Grossmann; David Dulin

Incorporation of arabinose-CTP and arabinose-UTP inhibit viral polymerases by inducing long pauses 阿拉伯糖-CTP和阿拉伯糖-UTP的掺入通过诱导长暂停来抑制病毒聚合酶

Journal of Biological Chemistry

IF3.9

2025-12-09

OAAI

Ziyang Xiao; Arnab Das; Abha Jain; Thomas K. Anderson; Craig E. Cameron; Jamie J. Arnold; David Dulin; Robert N. Kirchdoerfer

A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent 组装后的构象变化使SARS-CoV-2聚合酶获得延伸活性。

NUCLEIC ACIDS RESEARCH

IF13.1

2025-06-10

PREAI

Klein, Misha; Das, Arnab; Bera, Subhas C.; Anderson, Thomas K.; Kocincova, Dana; Lee, Hery W.; Wang, Bing; Papini, Flavia S.; Marecki, John C.; Arnold, Jamie J.; Cameron, Craig E.; Raney, Kevin D.; Artsimovitch, Irina; Gotte, Mathias; Kirchdoerfer, Robert N.; Depken, Martin; Dulin, David

Interfering with nucleotide excision by the coronavirus 3′-to-5′ exoribonuclease

NUCLEIC ACIDS RESEARCH

IF13.1

2022-12-22

OAAI

Chinthapatla, Rukesh; Sotoudegan, Mohamad; Srivastava, Pankaj; Anderson, Thomas K.; Moustafa, Ibrahim M.; Passow, Kellan T.; Kennelly, Samantha A.; Moorthy, Ramkumar; Dulin, David; Feng, Joy Y.; Harki, Daniel A.; Kirchdoerfer, Robert N.; Cameron, Craig E.; Arnold, Jamie J.

Quantitative parameters of bacterial RNA polymerase open-complex formation, stabilization and disruption on a consensus promoter

NUCLEIC ACIDS RESEARCH

IF13.1

2022-07-12

OAAI

Bera, Subhas C.; America, Pim P. B.; Maatsola, Santeri; Seifert, Mona; Ostrofet, Eugeniu; Cnossen, Jelmer; Spermann, Monika; Papini, Flavia S.; Depken, Martin; Malinen, Anssi M.; Dulin, David

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

ELIFE

IF0

2021-10-07

PREAI

Seifert, Mona; Bera, Subhas C.; van Nies, Pauline; Kirchdoerfer, Robert N.; Shannon, Ashleigh; Le, Thi-Tuyet-Nhung; Meng, Xiangzhi; Xia, Hongjie; Wood, James M.; Harris, Lawrence D.; Papini, Flavia S.; Arnold, Jamie J.; Almo, Steven; Grove, Tyler L.; Shi, Pei-Yong; Xiang, Yan; Canard, Bruno; Depken, Martin; Cameron, Craig E.; Dulin, David

The nucleotide addition cycle of the SARS-CoV-2 polymerase

CELL REPORTS

IF6.9

2021-08-01

OAAI

Bera, Subhas Chandra; Seifert, Mona; Kirchdoerfer, Robert N.; van Nies, Pauline; Wubulikasimu, Yibulayin; Quack, Salina; Papini, Flavia S.; Arnold, Jamie J.; Canard, Bruno; Cameron, Craig E.; Depken, Martin; Dulin, David

Temperature controlled high-throughput magnetic tweezers show striking difference in activation energies of replicating viral RNA-dependent RNA polymerases

NUCLEIC ACIDS RESEARCH

IF13.1

2020-04-14

OAAI

Seifert, Mona; van Nies, Pauline; Papini, Flavia S.; Arnold, Jamie J.; Poranen, Minna M.; Cameron, Craig E.; Depken, Martin; Dulin, David

High-yield fabrication of DNA and RNA constructs for single molecule force and torque spectroscopy experiments

NUCLEIC ACIDS RESEARCH

IF13.1

2019-10-04

OAAI

Papini, Flavia S.; Seifert, Mona; Dulin, David

Correction-free force calibration for magnetic tweezers experiments (vol 8, 17811, 2018)

SCIENTIFIC REPORTS

IF3.9

2018-12-10

OAAI

Ostrofet, Eugen; Papini, Flavia Stal; Dulin, David

Correction-free force calibration for magnetic tweezers experiments

SCIENTIFIC REPORTS

IF3.9

2018-10-29

OAAI

Ostrofet, Eugen; Papini, Flavia Stal; Dulin, David

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria

NATURE COMMUNICATIONS

IF15.7

2018-04-16

OAAI

Dulin, David; Bauer, David L. V.; Malinen, Anssi M.; Bakermans, Jacob J. W.; Kaller, Martin; Morichaud, Zakia; Petushkov, Ivan; Depken, Martin; Brodolin, Konstantin; Kulbachinskiy, Andrey; Kapanidis, Achillefs N.

Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers

CELL REPORTS

IF6.9

2017-10-01

OAAI

Dulin, David; Arnold, Jamie J.; van Laar, Theo; Oh, Hyung-Suk; Lee, Cheri; Perkins, Angela L.; Harki, Daniel A.; Depken, Martin; Cameron, Craig E.; Dekker, Nynke H.

Kinetics of CrPV and HCV IRES-mediated eukaryotic translation using single-molecule fluorescence microscopy 使用单分子荧光显微镜观察CrPV和HCV IRES介导的真核翻译动力学

RNA

IF5

2017-08-02

OAAI

Bugaud, Olivier; Barbier, Nathalie; Chommy, Helene; Fiszman, Nicolas; Le Gall, Antoine; Dulin, David; Saguy, Matthieu; Westbrook, Nathalie; Perronet, Karen; Namy, Olivier

Probing the salt dependence of the torsional stiffness of DNA by multiplexed magnetic torque tweezers

NUCLEIC ACIDS RESEARCH

IF13.1

2017-04-29

OAAI

Kriegel, Franziska; Ermann, Niklas; Forbes, Ruaridh; Dulin, David; Dekker, Nynke H.; Lipfert, Jan

研究方向