Martin Hemberg; Federico Marini; Shila Ghazanfar; Ahmad Al Ajami; Najla Abassi; Benedict Anchang; Bérénice A. Benayoun; Yue Cao; Ken Chen; Yesid Cuesta-Astroz; Zachary DeBruine; Calliope A. Dendrou; Iwijn De Vlaminck; Katharina Imkeller; Ilya Korsunsky; Alex R. Lederer; Jessica Jingyi Li; Pieter Meysman; Clint L. Miller; Kerry A. Mullan; Uwe Ohler; Pratibha Panwar; Nikolaos Patikas; Jonas Schuck; Jacqueline H. Y. Siu; Timothy J. Triche; Alex Tsankov; Sander W. van der Laan; Masanao Yajima; Jean Yang; Fabio Zanini; Ivana Jelic

Smooth muscle expression of RNA editing enzyme ADAR1 controls activation of the RNA sensor MDA5 in atherosclerosis

平滑肌细胞中RNA编辑酶ADAR1的表达调控动脉粥样硬化中RNA传感器MDA5的激活。

cardiovascular research

IF10.8

2025-09-160

Clonal haematopoiesis of indeterminate potential and mortality in coronary artery disease

克隆性中性粒细胞发育异常潜能与冠状动脉疾病死亡率

EUROPEAN HEART JOURNAL

IF35.6

2025-09-013

OAAI

von Scheidt, Moritz; Adkar, Shaunak S.; Krefting, Johannes; Hoermann, Gregor; Meggendorfer, Manja; Bauer, Sabine; Mitchell, Shaneice; Pugach, Irina; Friess, Christian; Ma, Angela; Hao, Ke; Steigerwald, Sophia; Wahle, Maria; Kessler, Thorsten; Schwab, Marius; Voll, Felix; Mokry, Michal; Sofokleous, Charalampos; Palm, Kaylin C. A.; Bongiovanni, Dario; Fleig, Julia; Oldenbuettel, Lilith; Chen, Zhifen; Hecker, Judith S.; Bassermann, Florian; Maegdefessel, Lars; Graw, Matthias; Ruusalepp, Arno; Hilgendorf, Ingo; Leuschner, Florian; Sager, Hendrik B.; Heimlich, J. Brett; Koenig, Wolfgang; Cremer, Sebastian; Leistner, David M.; Abplanalp, Wesley T.; Dimmeler, Stefanie; Zeiher, Andreas M.; van der Laan, Sander W.; Pasterkamp, Gerard; Braun, Christian; Jaiswal, Siddhartha; Kovacic, Jason C.; Kern, Wolfgang; Haferlach, Claudia; Mann, Matthias; Cassese, Salvatore; Kastrati, Adnan; Haferlach, Torsten; Leeper, Nicholas J.; Bjorkegren, Johan L. M.; Schunkert, Heribert

Proteomic profiling reveals a higher presence of glycolytic enzymes in human atherosclerotic lesions with unfavourable histological characteristics

蛋白质组学分析揭示了在具有不良组织学特征的人类动脉粥样硬化斑块中糖酵解酶的含量更高。

CARDIOVASCULAR RESEARCH

IF13.3

2025-06-013

OAAI

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2024-06-011

The Effects of FABP4 on Cardiovascular Disease in the Aging Population

CURRENT ATHEROSCLEROSIS REPORTS

IF5.2

2024-05-033

OAAI

Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis

蛋白质基因组数据整合揭示CXCL10是动脉粥样硬化IL-6信号传导的潜在下游因果介质

CIRCULATION

IF38.6

2024-02-2712

Association between BMD and coronary artery calcification: an observational and Mendelian randomization study

BMD与冠状动脉钙化之间的关系: 一项观察性和孟德尔随机化研究

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2024-02-041

Multi-ancestry genetic analysis of gene regulation in coronary arteries prioritizes disease risk loci

CELL GENOMICS

IF9

2024-01-011

OAAI

Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis

CELL REPORTS

IF6.9

2023-11-0115

Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

全基因组关联荟萃分析确定腹主动脉瘤的风险位点，并强调PCSK9作为治疗靶点

NATURE GENETICS

IF31.8

2023-10-1613

OAAI

Roychowdhury, Tanmoy; Klarin, Derek; Levin, Michael G.; Spin, Joshua M.; Rhee, Yae Hyun; Deng, Alicia; Headley, Colwyn A.; Tsao, Noah L.; Gellatly, Corry; Zuber, Verena; Shen, Fred; Hornsby, Whitney E.; Laursen, Ina Holst; Verma, Shefali S.; Locke, Adam E.; Einarsson, Gudmundur; Thorleifsson, Gudmar; Graham, Sarah E.; Dikilitas, Ozan; Pattee, Jack W.; Judy, Renae L.; Pauls-Verges, Ferran; Nielsen, Jonas B.; Wolford, Brooke N.; Brumpton, Ben M.; Dilme, Jaume; Peypoch, Olga; Juscafresa, Laura Calsina; Edwards, Todd L.; Li, Dadong; Banasik, Karina; Brunak, Soren; Jacobsen, Rikke L.; Garcia-Barrio, Minerva T.; Zhang, Jifeng; Rasmussen, Lars M.; Lee, Regent; Handa, Ashok; Wanhainen, Anders; Mani, Kevin; Lindholt, Jes S.; Obel, Lasse M.; Strauss, Ewa; Oszkinis, Grzegorz; Nelson, Christopher P.; Saxby, Katie L.; van Herwaarden, Joost A.; van der Laan, Sander W.; van Setten, Jessica; Camacho, Mercedes; Davis, Frank M.; Wasikowski, Rachael; Tsoi, Lam C.; Gudjonsson, Johann E.; Eliason, Jonathan L.; Coleman, Dawn M.; Henke, Peter K.; Ganesh, Santhi K.; Chen, Y. Eugene; Guan, Weihua; Pankow, James S.; Pankratz, Nathan; Pedersen, Ole B.; Erikstrup, Christian; Tang, Weihong; Hveem, Kristian; Gudbjartsson, Daniel; Gretarsdottir, Solveig; Thorsteinsdottir, Unnur; Holm, Hilma; Stefansson, Kari; Ferreira, Manuel A.; Baras, Aris; Kullo, Iftikhar J.; Ritchie, Marylyn D.; Christensen, Alex H.; Iversen, Kasper K.; Eldrup, Nikolaj; Sillesen, Henrik; Ostrowski, Sisse R.; Bundgaard, Henning; Ullum, Henrik; Burgess, Stephen; Gill, Dipender; Gallagher, Katherine; Sabater-Lleal, Maria; Surakka, Ida; Jones, Gregory T.; Bown, Matthew J.; Tsao, Philip S.; Willer, Cristen J.; Damrauer, Scott M.

The accumulation of erythrocytes quantified and visualized by Glycophorin C in carotid atherosclerotic plaque reflects intraplaque hemorrhage and pre-procedural neurological symptoms

SCIENTIFIC REPORTS

IF3.9

2023-10-100

OAAI

Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification

多血统全基因组研究确定冠状动脉钙化的效应基因和药物途径

NATURE GENETICS

IF31.8

2023-09-2822

Kavousi, Maryam; Bos, Maxime M.; Barnes, Hanna J.; Cardenas, Christian L. Lino; Wong, Doris; Lu, Haojie; Hodonsky, Chani J.; Landsmeer, Lennart P. L.; Turner, Adam W.; Kho, Minjung; Hasbani, Natalie R.; de Vries, Paul S.; Bowden, Donald W.; Chopade, Sandesh; Deelen, Joris; Benavente, Ernest Diez; Guo, Xiuqing; Hofer, Edith; Hwang, Shih-Jen; Lutz, Sharon M.; Lyytikainen, Leo-Pekka; Slenders, Lotte; Smith, Albert V.; Stanislawski, Maggie A.; van Setten, Jessica; Wong, Quenna; Yanek, Lisa R.; Becker, Diane M.; Beekman, Marian; Budoff, Matthew J.; Feitosa, Mary F.; Finan, Chris; Hilliard, Austin T.; Kardia, Sharon L. R.; Kovacic, Jason C.; Kral, Brian G.; Langefeld, Carl D.; Launer, Lenore J.; Malik, Shaista; Hoesein, Firdaus A. A. Mohamed; Mokry, Michal; Schmidt, Reinhold; Smith, Jennifer A.; Taylor, Kent D.; Terry, James G.; van der Grond, Jeroen; van Meurs, Joyce; Vliegenthart, Rozemarijn; Xu, Jianzhao; Young, Kendra A.; Zilhao, Nuno R.; Zweiker, Robert; Assimes, Themistocles L.; Becker, Lewis C.; Bos, Daniel; Carr, J. Jeffrey; Cupples, L. Adrienne; de Kleijn, Dominique P. V.; de Winther, Menno; den Ruijter, Hester M.; Fornage, Myriam; Freedman, Barry I.; Gudnason, Vilmundur; Hingorani, Aroon D.; Hokanson, John E.; Ikram, M. Arfan; Isgum, Ivana; Jacobs, David R., Jr.; Kahonen, Mika; Lange, Leslie A.; Lehtimaki, Terho; Pasterkamp, Gerard; Raitakari, Olli T.; Schmidt, Helena; Slagboom, P. Eline; Uitterlinden, Andre G.; Vernooij, Meike W.; Bis, Joshua C.; Franceschini, Nora; Psaty, Bruce M.; Post, Wendy S.; Rotter, Jerome I.; Bjorkegren, Johan L. M.; O'Donnell, Christopher J.; Bielak, Lawrence F.; Peyser, Patricia A.; Malhotra, Rajeev; van der Laan, Sander W.; Miller, Clint L.

Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes

CIRCULATION RESEARCH

IF16.2

2023-09-1513

OAAI

Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization

ARTHRITIS & RHEUMATOLOGY

IF10.9

2023-08-0319

OAAI

Zheng, Jie; Wheeler, Eleanor; Pietzner, Maik; Andlauer, Till F. M.; Yau, Michelle S.; Hartley, April E.; Brumpton, Ben Michael; Rasheed, Humaira; Kemp, John P.; Frysz, Monika; Robinson, Jamie; Reppe, Sjur; Prijatelj, Vid; Gautvik, Kaare M.; Falk, Louise; Maerz, Winfried; Gergei, Ingrid; Peyser, Patricia A.; Kavousi, Maryam; de Vries, Paul S.; Miller, Clint L.; Bos, Maxime; van Der Laan, Sander W.; Malhotra, Rajeev; Herrmann, Markus; Scharnagl, Hubert; Kleber, Marcus; Dedoussis, George; Zeggini, Eleftheria; Nethander, Maria; Ohlsson, Claes; Lorentzon, Mattias; Wareham, Nick; Langenberg, Claudia; Holmes, Michael V.; Davey Smith, George; Tobias, Jonathan H.

Sander W. van der Laan

个人简介

教育背景

工作经历

荣誉奖项

研究方向