Marcelo B. Sztein - Publications, H-index & Citations

Marcelo B. Sztein

center for vaccine development and global health

68H指数

309论文数

1.3W被引数

收录论文 94

发表时间

Distinct time-dependent S. Typhi-specific CD8+ T cell programs are associated with clinical outcome following Ty21a immunization and wild-type S. Typhi challenge in humans 不同时间依赖性的S. Typhi特异性CD8+ T细胞程序与Ty21a免疫及野生型S. Typhi挑战后的人类临床结局相关

Frontiers in Cellular and Infection Microbiology

IF4.8

2026-10-02

OAAI

JS Jayaum S. Booth; RR Rekha R. Rapaka; MA Monica A. McArthur; SF Stephanie Fresnay; TC Thomas C. Darton; BG Bing Guo; CS Claire S. Waddington; MM Myron M. Levine; AJ Andrew J. Pollard; MB Marcelo B. Sztein

First-in-Human Evaluation of the Safety, Genetic Stability, and Immunogenicity of an Attenuated Shigella flexneri 2a Live Vector Expressing Enterotoxigenic Escherichia coli Antigens, Vaccine Strain CVD 1208S-122 首次人体安全性、遗传稳定性和免疫原性评价：表达产肠毒素大肠杆菌抗原的减毒志贺氏菌2a活载体疫苗株CVD 1208S-122

The Journal of Infectious Diseases

IF0

2026-07-15

PREAI

Wilbur H Chen; Eileen M Barry; Franklin R Toapanta; Marcela F Pasetti; Marcelo B Sztein; Jasnehta Permala-Booth; Sharon M Tennant; Justin R Ortiz; Constance Thomas; Megan McGilvray; Lynnee Roane; Reva Datar; Yuanyuan Liang; Myron M Levine

Safety and Immunogenicity of a Trivalent Salmonella Conjugate Vaccine to S. Typhi, S. Typhimurium, and S. Enteritidis 三价沙门氏菌结合疫苗对S. Typhi、S. Typhimurium和S. Enteritidis的安全性与免疫原性

Journal of Infectious Diseases

IF4.5

2026-03-01

PREAI

Chen, Wilbur H.; Beckett, Charmagne G.; Al-Ibrahim, Mohamed; Datar, Reva; Sikorski, Michael J.; Liang, Yuanyuan; Pasetti, Marcela F.; Sztein, Marcelo B.; Wahid, Rezwanul; Tennant, Sharon M.; Simon, Raphael; Baliban, Scott M.; Galen, James E.; Lees, Andrew; Ella, Raches; Mohan, Krishna; Naidu, M. Gangadhara; Rao, D. Yogeswara; Ella, Krishna M.; Levine, Myron M.

An intranasal adjuvanted, recombinant influenza A/H5 vaccine primes against diverse H5N1 clades: a phase I trial 一种鼻内佐剂重组甲型流感病毒A/H5疫苗可针对多种H5N1亚系产生初始免疫应答：一项I期临床试验

Nature Communications

IF15.7

2025-11-06

OAAI

Meagan E. Deming; Franklin R. Toapanta; Marcela Pasetti; Hana Golding; Surender Khurana; Tarek Hamouda; Ali Fattom; Yuanyuan Liang; Sharon M. Tennant; Megan F. McGilvray; Paula J. Bernal; Jennifer J. Oshinsky; Shrimati Datta; Jasnehta Permala Booth; Lynda Coughlan; Kathleen M. Neuzil; Chad D. Costley; Karen L. Kotloff; Marcelo B. Sztein; Justin R. Ortiz

A combination typhoid and non-typhoidal Salmonella polysaccharide conjugate vaccine in healthy adults: a randomized, placebo-controlled phase 1 trial 一种伤寒与非伤寒沙门氏菌多糖结合疫苗在健康成人中的研究：一项随机、安慰剂对照的1期临床试验

Nature Medicine

IF50

2025-10-08

PREAI

Wilbur H. Chen; Robin S. Barnes; Michael J. Sikorski; Reva Datar; Roohali Sukhavasi; Yuanyuan Liang; Rekha R. Rapaka; Marcela F. Pasetti; Marcelo B. Sztein; Rezwanul Wahid; Sharon M. Tennant; Raphael Simon; Scott M. Baliban; James E. Galen; Andrew Lees; Biana Bernshtein; Galit Alter; Raches Ella; Krishna Mohan; M. Gangadhara Naidu; D. Yogeswar Rao; Krishna M. Ella; Myron M. Levine

Cord blood innate-like T cell responses in neonates born to healthy women and women living with HIV 健康女性及HIV感染者所生新生儿中的脐带血先天样T细胞应答

Frontiers in Immunology

IF5.9

2025-08-22

OAAI

David Rach; Hao-Ting Hsu; Nginache Nampota-Nkomba; Godfrey Mvula; Felix A. Mkandawire; Osward M. Nyirenda; Bernadette Hritzo; Francesca Boldrin; Giulia Degiacomi; Laura Cioetto Mazzabò; Riccardo Manganelli; Andrea G. Buchwald; Franklin R. Toapanta; Marcelo B. Sztein; Miriam K. Laufer; Kirsten E. Lyke; Cristiana Cairo

Safety and immunogenicity in humans of enterotoxigenic Escherichia coli double mutant heat-labile toxin administered intradermally

NPJ VACCINES

IF6.5

2025-02-01

OAAI

Pasetti, Marcela F.; Milletich, Patricia L.; White, Jessica A.; Butts, Jessica; Brady, Rebecca C.; Dickey, Michelle D.; Ballou, Cassandra; Maier, Nicole; Sztein, Marcelo B.; Baqar, Shahida; Bourgeois, A. Louis; Bernstein, David I.

Epigenetic regulation in epithelial cells and innate lymphocyte responses to S. Typhi infection: insights into IFN-γ production and intestinal immunity

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-09-20

OAAI

Salerno-Goncalves, Rosangela; Chen, Haiyan; Bafford, Andrea C.; Sztein, Marcelo B.

Role of circulating T follicular helper subsets following Ty21a immunization and oral challenge with wild type S. Typhi in humans

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-09-12

OAAI

Booth, Jayaum S.; Rapaka, Rekha R.; Mcarthur, Monica A.; Fresnay, Stephanie; Darton, Thomas C.; Blohmke, Christoph J.; Jones, Claire; Waddington, Claire S.; Levine, Myron M.; Pollard, Andrew J.; Sztein, Marcelo B.

Role of cellular effectors in the induction and maintenance of IgA responses leading to protective immunity against enteric bacterial pathogens

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-09-11

OAAI

Carreto-Binaghi, Laura E.; Sztein, Marcelo B.; Booth, Jayaum S.

Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-08-27

OAAI

Toapanta, Franklin R.; Hu, Jingping; Shirey, Kari Ann; Bernal, Paula J.; Levine, Myron M.; Darton, Thomas C.; Waddington, Claire S.; Pollard, Andrew J.; Sztein, Marcelo B.

Early host immune responses in a human organoid-derived gallbladder monolayer to Salmonella Typhi strains from patients with acute and chronic infections: a comparative analysis

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-03-12

OAAI

Salerno-Goncalves, Rosangela; Chen, Haiyan; Bafford, Andrea C.; Izquierdo, Mariana; Hormazabal, Juan Carlos; Lagos, Rosanna; Tettelin, Herve; D'Mello, Adonis; Booth, Jayaum S.; Fasano, Alessio; Levine, Myron M.; Sztein, Marcelo B.

Dietary fiber pectin: challenges and potential anti-inflammatory benefits for preterms and newborns

FRONTIERS IN NUTRITION

IF5.1

2024-01-12

OAAI

Donadio, Janaina L. S.; Fabi, Joao Paulo; Sztein, Marcelo B.; Salerno-Goncalves, Rosangela

Further characterization of Shigella-specific (memory) B cells induced in healthy volunteer recipients of SF2a-TT15, a Shigella flexneri 2a synthetic glycan-based vaccine candidate

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-10-31

OAAI

Toapanta, Franklin R.; Hu, Jingping; Meron-Sudai, Shiri; Mulard, Laurence A.; Phalipon, Armelle; Cohen, Dani; Sztein, Marcelo B.

Reduced immunogenicity of a live Salmonella enterica serovar Typhimurium vaccine in aged mice

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-05-03

OAAI

Allen, Jessica C.; Toapanta, Franklin R.; Baliban, Scott M.; Sztein, Marcelo B.; Tennant, Sharon M.

Secretory-IgA binding to intestinal microbiota attenuates inflammatory reactions as the intestinal barrier of preterm infants matures 随着早产儿肠道屏障的成熟，分泌型IgA与肠道菌群的结合减轻了炎症反应

CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IF3.8

2023-04-18

OAAI

Mahdally, Sarah M.; Izquierdo, Mariana; Viscardi, Rose M.; Magder, Laurence S.; Crowley, Helena M.; Bafford, Andrea C.; Drachenberg, Cinthia B.; Farfan, Mauricio J.; Fasano, Alessio; Sztein, Marcelo B.; Salerno-Goncalves, Rosangela

E6020, a TLR4 Agonist Adjuvant, Enhances Both Antibody Titers and Isotype Switching in Response to Immunization with Hapten-Protein Antigens and Is Diminished in Mice with TLR4 Signaling Insufficiency

JOURNAL OF IMMUNOLOGY

IF3.4

2022-11-15

OAAI

Gopalakrishnan, Archana; Richard, Katharina; Wahid, Rezwanul; Harley, Regina; Sztein, Marcelo B.; Hawkins, Lynn D.; Vogel, Stefanie N.

Controlled human infectious models, a path forward in uncovering immunological correlates of protection: Lessons from enteric fevers studies

FRONTIERS IN MICROBIOLOGY

IF4.5

2022-09-20

OAAI

Sztein, Marcelo B.; Booth, Jayaum S.

Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever

CELLULAR IMMUNOLOGY

IF2.9

2022-08-01

OAAI

Salerno-Goncalves, Rosangela; Fresnay, Stephanie; Magder, Laurence; Darton, Thomas C.; Waddington, Claire S.; Blohmke, Christoph J.; Angus, Brian; Levine, Myron M.; Pollard, Andrew J.; Sztein, Marcelo B.

B Cells Control Mucosal-Associated Invariant T Cell Responses to Salmonella enterica Serovar Typhi Infection Through the CD85j HLA-G Receptor

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-10-01

OAAI

Salerno-Goncalves, Rosangela; Rezwan, Tasmia; Luo, David; Tettelin, Herve; Sztein, Marcelo B.

研究方向