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D

Deepak Nagrath

Rice University

40H指数
224论文数
8.0K被引数
收录论文 115
发表时间
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Author Correction: Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer作者更正：苹果酸酶2基因组缺失赋予胰腺癌共致死性
errNature
IF48.5
err2026-09-17
err0
PREAI
errPrasenjit Dey; Joelle Baddour; Florian Muller; Chia Chin Wu; Huamin Wang; Wen-Ting Liao; Zangdao Lan; Alina Chen; Tony Gutschner; Yaan Kang; Jason Fleming; Nikunj Satani; Di Zhao; Abhinav Achreja; Lifeng Yang; Jiyoon Lee; Edward Chang; Giannicola Genovese; Andrea Viale; Haoqiang Ying; Giulio Draetta; Anirban Maitra; Y. Alan Wang; Deepak Nagrath; Ronald A. DePinho
err分享
err收藏
Oral nano-delivery of a gut microbial metabolite enhances T cell stemness for cancer immunotherapy口服纳米递送肠道微生物代谢物可增强T细胞干性以用于癌症免疫治疗
errNature Nanotechnology
IF34.9
err2026-08-10
err0
errOAAI
errKai Han; Young Seok Cho; Mariko Takahashi; Xingwu Zhou; Hannah E. Dobson; Kim Hutchings; Yuesong Wu; Youngseo Na; Fang Xie; Julia Crowther; Jinmei Wu; Jin Xu; Chuan Lee; Himani Jasewicz; Yujin Kim; Minal Nenwani; Olamide Animasahun; Fulei Wuchu; Anthony Andren; Harrison Wong; Emma Camp; Ziye Wan; Qi Wu; Li Zhang; Cheng Xu; Katherine Dong; Yao Xu; Anna Schwendeman; Grace Y. Chen; Yuying Xie; Costas A. Lyssiotis; Martin Clasby; Deepak Nagrath; Yu Leo Lei; James J. Moon
err分享
err收藏
Dual targeting of PI3Kγ and STING overcomes regulatory B cell- and myeloid cell-driven immune suppression in pancreatic cancer通过同时靶向PI3Kγ和STING克服胰腺癌中调节性B细胞和髓系细胞介导的免疫抑制
errNature Cancer
IF28.5
err2026-04-28
err0
PREAI
errChengyi Li; Fang Ke; Hongyi Zhao; Shuai Mao; Mahamadou Djibo; Linqi Huang; Miao He; Meilin Wang; Hanning Wen; Zhongwei Liu; Zhixin Yu; Zhihong Qi; Ana R. Xavier; Minal Nenwani; Bo Wen; Nicole Peterson; Vaibhav Sahai; Deepak Nagrath; Carrie L. Lucas; Matthias P. Wymann; Wei Gao; Lawrence Fong; Duxin Sun
err分享
err收藏
Mitochondrial targets in IDH1-mutated cholangiocarcinomaIDH1突变胆管癌的线粒体靶点
errHepatology Communications
IF4.6
err2026-02-26
err0
errOAAI
errCarvalho, Camila; Wuchu, Fulei; Peterson, Nicole; Nagrath, Deepak; Mohan, Arathi; Sahai, Vaibhav
err分享
err收藏
ZFTA-RELA ependymomas make itaconate to epigenetically drive fusion expression
errNature
IF48.5
err2026-02-01
err2
PREAI
errNatarajan, Siva Kumar; Lum, Joanna; Skeans, James Haggerty; Nenwani, Minal; Eyunni, Sanjana; Mota, Mateus; Bayliss, Jill M.; Deogharkar, Akash; Hamanishi, Erin Taya; Pun, Matthew; Sweha, Stefan R.; Hoffman, Simon; Young, Eleanor; Zhang, Qiuyang; Mehta, Rijul; Animasahun, Olamide; Narayanan, Pranav; Sunil, Sushanth; Parolia, Abhijit; Sajjakulnukit, Peter; Panwalkar, Pooja; Doherty, Robert; Clausen, Madison; Dang, Derek; Hawes, Debra; Yang, Fusheng; Santi, Mariarita; Judkins, Alexander R.; Wilson, Yelena; Vigil, Thomas; Franson, Andrea; Mortensen, Richard M.; Ozawa, Tatsuya; Griesinger, Andrea; Holland, Eric C.; Foreman, Nicholas K.; Michealraj, Kulandaimanuvel Antony; Agnihotri, Sameer; Taylor, Michael; Gilbertson, Richard J.; Koschmann, Carl; Chinnaiyan, Arul M.; Lyssiotis, Costas A.; Nagrath, Deepak; Venneti, Sriram
err分享
err收藏
BATF2 is a glutamine-responsive tumour suppressor required for type-I interferon-dependent anti-tumour immunityBATF2是一种对谷氨酰胺敏感的肿瘤抑制因子，是I型干扰素依赖性抗肿瘤免疫所必需的。
errNature Communications
IF15.7
err2025-12-29
err0
errOAAI
errWang Gong; Hülya F. Taner; Yuesong Wu; Yumin He; Xingwu Zhou; Zaiye Li; Xin Hu; Charisse Ursin; Kala Chand Debnath; Kohei Okuyama; Qiang Hu; Christopher R. Donnelly; Felipe Nör; Chamila D. Perera; Emily Bellile; Arash Yunesi; Zhiqian Zhai; Mei Zhao; Wanqing Cheng; Zackary R. Fitzsimonds; Luke Broses; Jiaqian Li; Shadmehr Demehri; Deepak Nagrath; Gregory T. Wolf; Andrew G. Sikora; Yanbao Yu; Haitao Wen; Lei Wei; Steven B. Chinn; Jeffrey N. Myers; Shizuo Akira; Yuying Xie; James J. Moon; Yu Leo Lei
err分享
err收藏
PNPLA3-I148M genetic variant rewires lipid metabolism to drive programmed cell death in human hepatocytesPNPLA3-I148M基因变异重编程脂质代谢，驱动人肝细胞程序性死亡。
errJCI INSIGHT
IF6.1
err2025-12-08
err1
errOAAI
errFlorentino, Rodrigo M.; Animasahun, Olamide; Haep, Nils; Nenwani, Minal; Omoloja, Kehinde; Altay, Leyla Nurcihan; Achreja, Abhinav; Morita, Kazutoyo; Motomura, Takashi; Diaz-Aragon, Ricardo; Faccioli, Lanuza A. P.; Sun, Yiyue; Liu, Zhenghao; Hu, Zhiping; Yang, Bo; Wuchu, Fulei; Shankaran, Ajay; Paserba, Miya; Baratta, Annalisa M.; Arazov, Shohrat; Kocas-Kilicarslan, Zehra N.; Meurs, Noah; Behari, Jaideep; Tafaleng, Edgar N.; Franks, Jonathan; Ostrowska, Alina; Tomiyama, Takahiro; Yugawa, Kyohei; Morinaga, Akinari; Wang, Zi; Takeishi, Kazuki; Gavlock, Dillon C.; Miedel, Mark; Taylor, D. Lansing; Fox, Ira J.; Yoshizumi, Tomoharu; Nagrath, Deepak; Soto-Gutierrez, Alejandro
err分享
err收藏
ZFTA-RELA ependymomas produce macrophage-associated itaconate as an oncometabolite to epigenetically sustain pathogenic fusion expressionZFTA-RELA室管膜瘤产生与巨噬细胞相关的衣康酸作为表观遗传学上维持致病融合表达的一种肿瘤代谢物。
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errNatarajan, Siva Kumar; Lum, Joanna; Haggerty-Skeans, James; Nenwani, Minal; Eyunni, Sanjana; Mota, Mateus; Bayliss, Jill; Deogharkar, Akash; Hamanishi, Erin; Hoffman, Simon; Young, Eleanor; Zhang, Qiuyang; Mehta, Rijul; Parolia, Abhijit; Sajjakulnukit, Peter; Doherty, Robert; Koschmann, Carl; Chinnaiyan, Arul; Lyssiotis, Costas; Nagrath, Deepak; Venneti, Sriram
err分享
err收藏
Microenvironment-derived acetylated amino acids promote glioblastoma DNA repair by rerouting glucose fates and enhancing histone acetylation微环境衍生的乙酰化氨基酸通过重定向葡萄糖命运和增强组蛋白乙酰化来促进胶质母细胞瘤DNA修复
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errPalavalasa, Sravya; Freeman, Jack; Gokul, Aditri; Singer, Ava; Scott, Andrew; Wilder-Romans, Kari; Baker, Emily; Korimerla, Navyateja; O'brien, Alexandra; Lin, Angelica; Peterson, Erik; Liang, Ningning; Xu, Jie; Ravikumar, Visweswaran; Sajjakulnukit, Peter; Wong, Harrison; Andren, Anthony; Zhang, Li; Shankar, Sunita; Bhadury, Sagnik; Heth, Jason; Zhou, Weihua; Rao, Arvind; Nagrath, Deepak; Al-Holou, Wajd; Lyssiotis, Costas; Wahl, Daniel
err分享
err收藏
Integrating scRNA-seq and13C-tracing delineates metabolic heterogeneity in the glioblastoma tumor microenvironment整合单细胞RNA测序和13C示踪技术揭示了胶质母细胞瘤肿瘤微环境中的代谢异质性
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errMeghdadi, Baharan; Al-Holou, Wajd; Scott, Andrew; Mittal, Anjali; Liang, Ningning; Palavalasa, Sravya; Achreja, Abhinav; Qi, Nathan; O'brien, Alexandra; Tarnal, Vijay; Zhou, Weihua; Lawrence, Theodore; Lyssiotis, Costas; Wahl, Daniel; Nagrath, Deepak
err分享
err收藏
Rewiring of cortical glucose metabolism fuels human brain cancer growth皮层葡萄糖代谢的重编程为人类脑癌的生长提供能量。
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errScott, Andrew; Mittal, Anjali; Meghdadi, Baharan; O'brien, Alexandra; Bailleul, Justine; Palavalasa, Sravya; Achreja, Abhinav; Zhou, Weihua; Xu, Jie; Lin, Angelica; Wilder-Romans, Kari; Liang, Ningning; Kothari, Ayesha; Korimerla, Navyateja; Edwards, Donna; Wu, Zhe; Feng, Jiane; Zhang, Li; Sajjakulnukit, Peter; Andren, Anthony; Park, Junyoung; Ten Hoeve, Johanna; Tarnal, Vijay; Redic, Kimberly; Qi, Nathan; Fischer, Joshua; Yang, Ethan; Regan, Michael; Stopka, Sylwia; Baquer, Gerard; Suresh, Krithika; Sarkaria, Jann; Lawrence, Theodore; Venneti, Sriram; Agar, Nathalie; Vlashi, Erina; Lyssiotis, Costas; Al-Holou, Wajd; Nagrath, Deepak; Wahl, Daniel
err分享
err收藏
BATF2 is a glutamine-responsive tumor suppressor essential for type I interferon-dependent anti-tumor immunity
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errLei, Y. Leo; Gong, Wang; Taner, Hulya F.; Wu, Yuesong; Li, Zaiye; Cheng, Wanqing; Hu, Qiang; Donnelly, Christopher R.; Nor, Felipe; He, Yumin; Zhai, Zhiqian; Fitzsimonds, Zackary Ray; Broses, Luke; Li, Jiaqian; Bellile, Emily; Okuyama, Kohei; Demehri, Shadmehr; Nagrath, Deepak; Wolf, Gregory T.; Yu, Yanbao; Wen, Haitao; Wei, Lei; Sikora, Andrew G.; Chinn, Steven B.; Akira, Shizuo; Xie, Yuying; Moon, James
err分享
err收藏
Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer苹果酸酶2、从头丝氨酸合成与苹果酸-天冬氨酸穿梭之间的相互作用驱动三阴性乳腺癌的代谢适应性
errCancer & Metabolism
IF5.3
err2025-10-15
err0
errOAAI
errJin Heon Jeon; Mark D. Slayton; Ben Krinkel; Olamide Animasahun; Ajay Shankaran; Fulei Wuchu; Minal Nenwani; Zackariah Farah; Julia Burke; Abhinav Achreja; Brisilda Nilaj; Kerslee Kohagen; Yi-Hsien Eu; Alyssa Rosenfeld; Mason Collard; Liwei Bao; Xu Cheng; Celina Kleer; Christopher Squire; Kerry Loomes; Deepak Nagrath; Sofia D. Merajver
err分享
err收藏
Local photocrosslinking of native tissue matrix regulates lung epithelial cell mechanosensing and function原位组织基质的光交联调控肺上皮细胞的力感受和功能
errNature Materials
IF38.5
err2025-09-05
err0
PREAI
errDonia W. Ahmed; Matthew L. Tan; Yuchen Liu; Jackson Gabbard; Esther Gao; Avinava Roy; Michael M. Hu; Firaol S. Midekssa; Miriam Stevens; Fulei Wuchu; Minal Nenwani; Jingyi Xia; Adam Abraham; Deepak Nagrath; Lin Han; Rachel L. Zemans; Brendon M. Baker; Claudia Loebel
err分享
err收藏
eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR-Mediated Metabolic RewiringeIF4E富集的外泌体通过HMGCR介导的代谢重编程诱导免疫抑制性巨噬细胞
errAdvanced Science
IF14.1
err2025-08-18
err0
errOAAI
errSonam Mittal; Minal Nenwani; Ishaque Pulikkal Kadamberi; Sudhir Kumar; Olamide Animasahun; Jasmine George; Shirng-Wern Tsaih; Prachi Gupta; Mona Singh; Anjali Geethadevi; Chandrima Dey; Noah Meurs; Ajay Shankaran; Pradeep Chaluvally Raghavan; Deepak Nagrath; Sunila Pradeep
err分享
err收藏
Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosis异柠檬酸脱氢酶1为组3型髓母细胞瘤的铜死亡做准备
errCancer Cell
IF44.5
err2025-05-15
err0
PREAI
errDerek Dang; Akash Deogharkar; John McKolay; Kyle S. Smith; Pooja Panwalkar; Simon Hoffman; Wentao Tian; Sunjong Ji; Ana P. Azambuja; Siva Kumar Natarajan; Joanna Lum; Jill Bayliss; Katie Manzeck; Stefan R. Sweha; Erin Hamanishi; Matthew Pun; Diya Patel; Sagar Rau; Olamide Animasahun; Abhinav Achreja; Martin P. Ogrodzinski; Jutta Diessl; Jennifer Cotter; Debra Hawes; Fusheng Yang; Robert Doherty; Andrea T. Franson; Allison R. Hanaford; Charles G. Eberhart; Eric H. Raabe; Brent A. Orr; Robert J. Wechsler-Reya; Brandon Chen; Costas A. Lyssiotis; Yatrik M. Shah; Sophia Y. Lunt; Ruma Banerjee; Alexander R. Judkins; John R. Prensner; Carl Koschmann; Sebastian M. Waszak; Deepak Nagrath; Marcos Simoes-Costa; Paul A. Northcott; Sriram Venneti
err分享
err收藏
REWIRING OF CORTICAL GLUCOSE METABOLISM FUELS HUMAN BRAIN CANCER GROWTH
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errScott, Andrew; Mittal, Anjali; Meghdadi, Baharan; Palavalasa, Sravya; Achreja, Abhinav; O'Brien, Alexandra; Kothari, Ayesha; Zhou, Weihua; Xu, Jie; Lin, Angelica; Wilder-Romans, Kari; Edwards, Donna; Wu, Zhe; Feng, Jiane; Andren, Anthony; Zhang, Li; Tarnal, Vijay; Redic, Kimberly; Qi, Nathan; Fischer, Joshua; Yang, Ethan; Regan, Michael; Stopka, Sylwia; Baquer, Gerard; Lawrence, Theodore; Venneti, Sriram; Agar, Nathalie; Lyssiotis, Costas; Al-Holou, Wajd; Nagrath, Deepak; Wahl, Daniel
err分享
err收藏
MACHINE LEARNING-BASED IDENTIFICATION OF METABOLIC FLUXES IN PATIENT BRAIN TUMORS
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errMeghdadi, Baharan; Mittal, Anjali; Scott, Andrew; Liang, Ningning; Palavalasa, Sravya; Achreja, Abhinav; O'Brien, Alexandra; Kothari, Ayesha; Zhou, Weihua; Xu, Jie; Lin, Angelica; Wilder-Romans, Kari; Edwards, Donna; Wu, Zhe; Feng, Jiane; Andren, Anthony; Zhang, Li; Tarnal, Vijay; Redic, Kimberly; Qi, Nathan; Lawrence, Theodore; Lyssiotis, Costas; Al-Holou, Wajd; Wahl, Daniel; Nagrath, Deepak
err分享
err收藏
Human-induced pluripotent stem cell-based hepatic modeling of lipid metabolism-associated TM6SF2-E167K variant基于人类诱导多能干细胞的脂质代谢相关TM6SF2-E167K变体的肝脏建模
errHEPATOLOGY
IF15.8
err2024-08-27
err0
errOAAI
errFaccioli, Lanuza A. P.; Sun, Yiyue; Animasahun, Olamide; Motomura, Takashi; Liu, Zhenghao; Kurihara, Takeshi; Hu, Zhiping; Yang, Bo; Cetin, Zeliha; Baratta, Annalisa M.; Shankaran, Ajay; Nenwani, Minal; Altay, Leyla Nurcihan; Huang, Linqi; Meurs, Noah; Franks, Jonathan; Stolz, Donna; Gavlock, Dillon C.; Miedel, Mark T.; Ostrowska, Alina; Florentino, Rodrigo M.; Fox, Ira J.; Nagrath, Deepak; Soto-Gutierrez, Alejandro
err分享
err收藏
Norovirus NS1/2 protein increases glutaminolysis for efficient viral replication
errPLOS PATHOGENS
IF4.9
err2024-07-08
err4
errOAAI
errHafner, Adam; Meurs, Noah; Garner, Ari; Azar, Elaine; Kannan, Aditya; Passalacqua, Karla D.; Nagrath, Deepak; Wobus, Christiane E.
err分享
err收藏

研究方向

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合作学者
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