Christopher M. Madl - Publications, H-index & Citations

Christopher M. Madl

Harvard University

22H指数

44论文数

2.9K被引数

收录论文 24

发表时间

Stress Relaxation Timescale and Hydrogel Network Connectivity Regulate Neural Progenitor Cell Stemness and Differentiation 应力松弛时间尺度和水凝胶网络连接性调控神经祖细胞的干性及分化

j. mater. chem. b

IF0

2026-04-03

OAAI

Lauren Brown; Daphne Bakker; Ping Zhou; Christopher Madl

Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis 选择性抑制基质力感受抑制心脏纤维化

NATURE

IF48.5

2025-04-30

PREAI

Cho, Sangkyun; Rhee, Siyeon; Madl, Christopher M.; Thomas, Dilip; Kim, Hyeonyu; Kojic, Ana; Shin, Hye Sook; Mahajan, Abhay; Jahng, James W.; Wang, Xi; Thai, Phung N.; Paik, David T.; Wang, Mingqiang; Mullen, Mckay; Baker, Natalie M.; Leitz, Jeremy; Mukherjee, Souhrid; Winn, Virginia D.; Woo, Y. Joseph; Blau, Helen M.; Wu, Joseph C.

Hydrogel biomaterials that stiffen and soften on demand reveal that skeletal muscle stem cells harbor a mechanical memory

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-08-20

PREAI

Madl, Christopher M.; Wang, Yu Xin; Holbrook, Colin A.; Su, Shiqi; Shi, Xuechen; Byfield, Fitzroy J.; Wicki, Gwendoline; Flaig, Iris A.; Blau, Helen M.

Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids

NATURE MATERIALS

IF38.5

2024-07-04

PREAI

LeSavage, Bauer L.; Zhang, Daiyao; Huerta-Lopez, Carla; Gilchrist, Aidan E.; Krajina, Brad A.; Karlsson, Kasper; Smith, Amber R.; Karagyozova, Kremena; Klett, Katarina C.; Huang, Michelle S.; Long, Christopher; Kaber, Gernot; Madl, Christopher M.; Bollyky, Paul L.; Curtis, Christina; Kuo, Calvin J.; Heilshorn, Sarah C.

Machine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors

NPJ REGENERATIVE MEDICINE

IF6.5

2023-01-14

OAAI

Togninalli, Matteo; Ho, Andrew T. V.; Madl, Christopher M. M.; Holbrook, Colin A. A.; Wang, Yu Xin; Magnusson, Klas E. G.; Kirillova, Anna; Chang, Andrew; Blau, Helen M. M.

Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments 工程微环境中再生生态位直接肌肉干细胞命运的生物物理矩阵线索

BIOMATERIALS

IF12.9

2021-08-01

OAAI

Madl, Christopher M.; Flaig, Iris A.; Holbrook, Colin A.; Wang, Yu Xin; Blau, Helen M.

Neural Progenitor Cells Alter Chromatin Organization and Neurotrophin Expression in Response to 3D Matrix Degradability 神经祖细胞响应3D基质降解性改变染色质组织和神经营养蛋白表达

ADVANCED HEALTHCARE MATERIALS

IF9.6

2020-08-02

OAAI

Madl, Christopher M.; LeSavage, Bauer L.; Khariton, Margarita; Heilshorn, Sarah C.

Rapid Diels-Alder Cross-linking of Cell Encapsulating Hydrogels

CHEMISTRY OF MATERIALS

IF7

2019-09-27

OAAI

Madl, Christopher M.; Heilshorn, Sarah C.

Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels 基质重塑增强3D水凝胶中神经祖细胞的分化能力

ADVANCED SCIENCE

IF14.1

2019-01-11

OAAI

Madl, Christopher M.; LeSavage, Bauer L.; Dewi, Ruby E.; Lampe, Kyle J.; Heilshorn, Sarah C.

Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates

BIOMATERIALS

IF12.9

2018-07-01

OAAI

Haugh, Matthew G.; Vaughan, Ted J.; Madl, Christopher M.; Raftery, Rosanne M.; McNamara, Laoise M.; O'Brien, Fergal J.; Heilshorn, Sarah C.

Engineering Hydrogel Microenvironments to Recapitulate the Stem Cell Niche 工程水凝胶微环境以重述干细胞生态位

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING

IF0

2018-06-04

130

OAAI

Madl, Christopher M.; Heilshorn, Sarah C.

Bioorthogonal Strategies for Engineering Extracellular Matrices 工程化细胞外基质的生物正交策略

ADVANCED FUNCTIONAL MATERIALS

IF19

2018-01-19

145

OAAI

Madl, Christopher M.; Heilshorn, Sarah C.

Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling

NATURE MATERIALS

IF38.5

2017-10-30

356

OAAI

Madl, Christopher M.; LeSavage, Bauer L.; Dewi, Ruby E.; Dinh, Cong B.; Stowers, Ryan S.; Khariton, Margarita; Lampe, Kyle J.; Duong Nguyen; Chaudhuri, Ovijit; Enejder, Annika; Heilshorn, Sarah C.

In-situ tissue regeneration through SDF-1α driven cell recruitment and stiffness-mediated bone regeneration in a critical-sized segmental femoral defect

ACTA BIOMATERIALIA

IF9.6

2017-09-01

PREAI

Cipitria, Amaia; Boettcher, Kathrin; Schoenhals, Sophia; Garske, Daniela S.; Schmidt-Bleek, Katharina; Ellinghaus, Agnes; Dienelt, Anke; Peters, Anja; Mehta, Manav; Madl, Christopher M.; Huebsch, Nathaniel; Mooney, David J.; Duda, Georg N.

Tyrosine-Selective Functionalization for Bio-Orthogonal Cross Linking of Engineered Protein Hydrogels

BIOCONJUGATE CHEMISTRY

IF3.9

2017-02-02

OAAI

Madl, Christopher M.; Heilshorn, Sarah C.

YAP-dependent mechanotransduction is required for proliferation and migration on native-like substrate topography

BIOMATERIALS

IF12.9

2017-01-01

OAAI

Mascharak, Shamik; Benitez, Patrick L.; Proctor, Amy C.; Madl, Christopher M.; Hu, Kenneth H.; Dewi, Ruby E.; Butte, Manish J.; Heilshorn, Sarah C.

Probing the Metabolomics of Stem Cell Differentiation with Biomaterials

CHEM

IF19.6

2016-08-01

OAAI

Madl, Christopher M.; Heilshorn, Sarah C.

Bio-Orthogonally Crosslinked, Engineered Protein Hydrogels with Tunable Mechanics and Biochemistry for Cell Encapsulation 具有可调力学和生物化学的生物正交交联工程蛋白水凝胶，用于细胞封装

ADVANCED FUNCTIONAL MATERIALS

IF19

2016-03-21

151

OAAI

Madl, Christopher M.; Katz, Lily M.; Heilshorn, Sarah C.

Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation

NATURE MATERIALS

IF38.5

2015-09-14

448

OAAI

Huebsch, Nathaniel; Lippens, Evi; Lee, Kangwon; Mehta, Manav; Koshy, Sandeep T.; Darnell, Max C.; Desai, Rajiv M.; Madl, Christopher M.; Xu, Maria; Zhao, Xuanhe; Chaudhuri, Ovijit; Verbeke, Catia; Kim, Woo Seob; Alim, Karen; Mammoto, Akiko; Ingber, Donald E.; Duda, Georg N.; Mooney, David J.

The collagen I mimetic peptide DGEA enhances an osteogenic phenotype in mesenchymal stem cells when presented from cell-encapsulating hydrogels

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

IF3.9

2015-05-24

OAAI

Mehta, Manav; Madl, Christopher M.; Lee, Shimwoo; Duda, Georg N.; Mooney, David J.

研究方向